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  • 1
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    Online Resource
    Mobitz Type II Second-Degree Atrioventricular Block in a Pilot : To Pace or Not to Pace?
    Indonesian Journal of Cardiology ; 2020
    In:  Indonesian Journal of Cardiology Vol. 41, No. 1 ( 2020-08-17), p. 25-31
    Details
    In: Indonesian Journal of Cardiology, Indonesian Journal of Cardiology, Vol. 41, No. 1 ( 2020-08-17), p. 25-31
    Abstract: Background: Atrioventricular (AV) block is a threatening condition that caused sudden loss of consciousness and death, notably if happened to aircraft pilot will compromise the reliability of flight operations and safety. Cardiac arrhythmia is well known as one of the main disqualifier for loss of flying license, and discriminating between benign and potentially significant rhythm abnormalities remains a challenge. The present case describes the electrophysiological feature of a high-grade AV block in an aircraft pilot. Case illustration: A 60-year-old male worked as commercial aircraft pilot presented with asymptomatic high-grade AV block during inflight Holter monitoring. He had never experienced any remarkable symptoms nor history of near syncope, but had a history of percutaneous coronary intervention (PCI) with one stent at left circumflex (LCx) coronary artery. Electrophysiology (EP) study revealed AH interval of 105 ms, HV interval of 50 ms, AV node effective refractory period of 280 ms and Weckenbach point of 330 ms, suggesting a normal EP study. Stimulation with atrial pacing and ATP showed prolongation of AH interval without changes in HV interval, showing the presence of a supra-Hisian AV node dysfunction. The highly demanding physiological environment in aircraft elucidate the likelihood of vagotonic cause of his condition and pacemaker implantation was not warranted. Conclusion: Atrioventricular (AV) block is an AV conduction disorder that can manifests in various symptoms and severity. Electrophysiology study is considered as a modality to locate the site of block that allows the avoidance of unnecessary permanent pacing and the appropriate prophylactic pacing.
    Type of Medium: Online Resource
    ISSN: 2620-4762 , 0126-3773
    URL: Article
    DOI: 10.30701/ijc.950
    Language: Unknown
    Publisher: Indonesian Journal of Cardiology
    Publication Date: 2020
    detail.hit.zdb_id: 2932484-1
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  • 2
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    Table1.docx
    Frontiers Media SA ; 2023
    In:  Frontiers in Cardiovascular Medicine Vol. 10 ( 2023-4-28)
    Details
    In: Frontiers in Cardiovascular Medicine, Frontiers Media SA, Vol. 10 ( 2023-4-28)
    Abstract: Genetic factors contribute to the AF pathophysiology by altering the structural and functional properties of proteins involved in different cellular activities. MicroRNAs (miRNAs), which take part in structural and electrical remodeling during the AF evolution, are important genetic elements that must be considered. The aim of study is to determine correlation between the expression of miRNAs and the development of AF, as well as to explain any potential importance of genetic factors in the AF diagnosis. Methods and Results Online scientific databases, including Cochrane, ProQuest, PubMed, and Web of Science were used to conduct the literature search. The keywords were associated with or characterized the relationship between miRNAs and AF. The pooled sensitivity and specificity statistical parameters were analyzed using a random-effects model. The miRNAs had a combined sensitivity and specificity of 0.80 (95% CI = 0.70–0.87) and 0.75 (95% CI = 0.64–0.83) for the diagnosis of AF, respectively. The area under the SROC was 0.84 (95% CI = 0.81–0.87). The DOR was 11.80 (95% CI = 6.79–20.50). This study also revealed that miRNAs had a pooled PLR of 3.16 (95% CI = 2.24–4.45) and NLR of 0.27 (95% CI = 0.18–0.39) for the diagnosis of AF. The miR-425-5p demonstrated the highest sensitivity (0.96, 95% CI, 0.89–0.99). Conclusion The meta-analysis revealed substantial connection between miRNA expression dysregulation and AF, supporting the potential diagnostic role of miRNAs. The miR-425-5p has potential role as a biomarker for AF.
    Type of Medium: Online Resource
    ISSN: 2297-055X
    URL: Article
    URL: Article
    DOI: 10.3389/fcvm.2023.1128708
    DOI: 10.3389/fcvm.2023.1128708.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2781496-8
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  • 3
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    A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation
    MDPI AG ; 2022
    In:  Journal of Personalized Medicine Vol. 12, No. 2 ( 2022-02-17), p. 298-
    Details
    In: Journal of Personalized Medicine, MDPI AG, Vol. 12, No. 2 ( 2022-02-17), p. 298-
    Abstract: The superiority of second-generation cryoballoon (2G-CB) ablation versus contact force-sensing radiofrequency (CF-RF) ablation in patients with paroxysmal atrial fibrillation (AF) was assessed in this systematic review and meta-analysis. Freedom from atrial tachyarrhythmias (ATAs) (OR = 0.89; 95% confidence interval [CI] = 0.68 to 1.17; p = 0.41), freedom from AF (OR = 0.93; 95% CI = 0.65 to 1.35; p = 0.72), and acute pulmonary vein isolation (PVI) (OR = 1.17; 95% CI = 0.54 to 2.53; p = 0.70) between 2G-CB ablation and CF-RF ablation were not different. The procedure time for the 2G-CB ablation was shorter (MD = −18.78 min; 95% CI = −27.72 to −9.85 min; p 〈 0.01), while the fluoroscopy time was similar (MD = 2.66 min; 95% CI = −0.52 to 5.83 min; p = 0.10). In the 2G-CB ablation group, phrenic nerve paralysis was more common (OR = 5.74; 95% CI = 1.80 to 18.31; p = 〈 0.01). Regarding freedom from ATAs, freedom from AF, and acute PVI, these findings imply that 2G-CB ablation is not superior to CF-RF ablation in paroxysmal AF. Although faster than CF-RF ablation, 2G-CB ablation has a greater risk of phrenic nerve paralysis.
    Type of Medium: Online Resource
    ISSN: 2075-4426
    URL: Article
    DOI: 10.3390/jpm12020298
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662248-8
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  • 4
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    Mengatasi Aritmia, Mencegah Kematian Mendadak
    Faculty of Medicine Universitas Indonesia ; 2018
    In:  eJournal Kedokteran Indonesia Vol. 5, No. 3 ( 2018-01-17)
    Details
    In: eJournal Kedokteran Indonesia, Faculty of Medicine Universitas Indonesia, Vol. 5, No. 3 ( 2018-01-17)
    Type of Medium: Online Resource
    ISSN: 2338-6037 , 2338-1426
    URL: Article
    DOI: 10.23886/ejki.5.8192.
    Language: Unknown
    Publisher: Faculty of Medicine Universitas Indonesia
    Publication Date: 2018
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  • 5
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    Percutaneous transluminal septal myocardial ablation (PTSMA) of hypertrophic cardiomyopathy: Indonesian initial experience
    Faculty of Medicine, Universitas Indonesia ; 2010
    In:  Medical Journal of Indonesia
    Details
    In: Medical Journal of Indonesia, Faculty of Medicine, Universitas Indonesia
    Type of Medium: Online Resource
    ISSN: 2252-8083 , 0853-1773
    URL: Article
    DOI: 10.13181/mji.v19i3.401
    Language: Unknown
    Publisher: Faculty of Medicine, Universitas Indonesia
    Publication Date: 2010
    detail.hit.zdb_id: 2716886-4
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  • 6
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    SCN 5A gene mutations and the risk of ventricular fibrillation and syncope in Brugada syndrome patients: A meta‐analysis
    Wiley ; 2018
    In:  Journal of Arrhythmia Vol. 34, No. 5 ( 2018-10), p. 473-477
    Details
    In: Journal of Arrhythmia, Wiley, Vol. 34, No. 5 ( 2018-10), p. 473-477
    Abstract: Mutations in the gene encoding the main cardiac sodium channel (SCN5A) are the commonest genetic cause of Brugada syndrome (BrS). However, the effect of SCN5A mutations on the outcomes of ventricular fibrillation ( VF ) and syncope remains uncertain. To clarify this relationship, a meta‐analysis was performed. A comprehensive search was conducted to identify all eligible studies from PubMed, MEDLINE , EBSCO , ProQuest, Science Direct, Clinical Key, and Cochrane database for cohort studies of BrS populations that had been systematically tested for SCN 5A mutations. We did meta‐analysis to see the relationship between SCN 5A mutations and the occurrence of VF and/or syncope using RevMan 5.3. Five clinical studies met our criteria and included a total of 665 BrS patients. These studies included 45 patients with VF and 178 patients with syncope. We found that in BrS patients with SCN 5A mutations the rate of VF event was 30.7% while in patients without mutations was 28.5% (Risk Ratio [ RR ] = 1.11, [95% CI : 0.61, 2.00], P = 0.73, I 2 = 0%). The occurrence of syncope events was 35.9% in patients with SCN 5A mutations and 34.5% in patients without mutations ( RR = 1.12, [95% CI : 0.87, 1.45], P = 0.37, I 2 = 39%). Furthermore, the occurrence of combined VF and syncope events were similar between the 2 groups ( RR = 1.12, [95% CI : 0.89, 1.42], P = 0.34, I 2 = 11%). BrS patients with SCN 5A mutations exhibit a similar risk of future occurence of VF and/or syncope as compared to those without SCN 5A mutations.
    Type of Medium: Online Resource
    ISSN: 1880-4276 , 1883-2148
    URL: Issue
    URL: Article
    DOI: 10.1002/joa3.2018.34.issue-5
    DOI: 10.1002/joa3.12097
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2696593-8
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  • 7
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    Longer diagnosis‐to‐ablation time is associated with recurrence of atrial fibrillation after catheter ablation—Systematic review and meta‐analysis
    Wiley ; 2020
    In:  Journal of Arrhythmia Vol. 36, No. 2 ( 2020-04), p. 289-294
    Details
    In: Journal of Arrhythmia, Wiley, Vol. 36, No. 2 ( 2020-04), p. 289-294
    Abstract: Diagnosis‐to‐ablation time (DTAT) has been postulated to be one of the predictors of atrial fibrillation (AF) recurrence, and it is a “modifiable” risk factor unlike that of many electrocardiographic or echocardiographic parameters. This development may change our consideration for ablation. In this systematic review and meta‐analysis, we aim to analyze the latest evidence on the importance of DTAT and whether they predict the AF recurrence after catheter ablation. Methods We performed a comprehensive search on topics that assess diagnosis‐to‐ablation time (DTAT) and AF recurrence from inception up until August 2019 through PubMed, EuropePMC, Cochrane Central Database, and ClinicalTrials.gov . Results There was a total of 3548 patients from six studies. Longer DTAT was associated with increased risk for AF recurrence in all studies included. Meta‐analysis of these studies showed that DTAT had a hazard ratio (HR) of 1.19 [1.02, 1.39], P  = .03; I 2 : 92% for AF recurrence. Upon sensitivity analysis by removing a study, HR became 1.24 [1.16, 1.32], P   〈  .001; I 2 : 29%. Meta‐analysis on DTAT time 〉 3 years had HR 1.73 [1.54, 1.93], P   〈  .001; I 2 : 45% for the recurrence of AF. Upon subgroup analysis of data that compared 〉 6 years to 〈 1 year, the HR was 1.93 [1.62, 2.29], P   〈  .001; I 2 : 0%. Conclusion Longer DTAT time is associated with an increased risk of AF recurrence. Hence, determining management at the earliest possible moment to avoid delay is of utmost importance.
    Type of Medium: Online Resource
    ISSN: 1880-4276 , 1883-2148
    URL: Issue
    URL: Article
    DOI: 10.1002/joa3.v36.2
    DOI: 10.1002/joa3.12294
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2696593-8
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  • 8
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    Left atrial appendage closure device implantation guided with fluoroscopy only: Long‐term results
    Wiley ; 2019
    In:  Journal of Arrhythmia Vol. 35, No. 2 ( 2019-04), p. 262-266
    Details
    In: Journal of Arrhythmia, Wiley, Vol. 35, No. 2 ( 2019-04), p. 262-266
    Abstract: Left atrial appendage (LAA) closure device is an alternative to anticoagulants for stroke prevention in selected atrial fibrillation (AF) patients. The LAA device implantation is safe with short period of learning curve. The standard implantation technique warrants a transesophageal echocardiography (TEE) guided and general anesthesia. In region of Asia Pacific as well as Indonesia, both TEE and general anesthesia are not always available in district hospital. We studied the safety and efficacy of Amplatzer Cardiac Plug (ACP) implantation guided by fluoroscopy only and without general anesthesia. Methods Consecutive nonvalvular AF patients with CHA 2 DS 2 VASc score of ≥2 and HASBLED score of ≥3 are participated. Patients requiring long‐life anticoagulant for any other indication are excluded. The choice of implanted first or second‐generation ACP is that with excess size of 2‐4 mm of measured landing zone diameter. Results Twenty‐five subjects were implanted ACP by means fluoroscopy only (Group A) and 28 subjects using standard technique group (Group B). The median AF duration was 36 months (6‐276 months) and majority of patients (49%) are having permanent AF. The mean CHA2DS2VASc score is 3.9 ± 1.63. Successful implantation of ACPs was 96% in both groups. Nonfatal pericardial effusion occurred in three patients. During 75 weeks of follow‐up period, there were no significant differences of stroke event and death between groups. Conclusion ACP implantation guided with fluoroscopy only is feasible and safe.
    Type of Medium: Online Resource
    ISSN: 1880-4276 , 1883-2148
    URL: Issue
    URL: Article
    DOI: 10.1002/joa3.2019.35.issue-2
    DOI: 10.1002/joa3.12151
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2696593-8
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  • 9
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    Antibiotic envelope is associated with reduction in cardiac implantable electronic devices infections especially for high‐power device—Systematic review and meta‐analysis
    Wiley ; 2020
    In:  Journal of Arrhythmia Vol. 36, No. 1 ( 2020-02), p. 166-173
    Details
    In: Journal of Arrhythmia, Wiley, Vol. 36, No. 1 ( 2020-02), p. 166-173
    Abstract: Infections after cardiac implantable electronic device (CIED) placement are associated with significant morbidity and mortality. The incidence of CIED is increasing overtime despite the optimal use of antimicrobial agents. This systematic review and meta‐analysis will address the latest evidence on the use of AE to mitigate the risk of CIED infection, and which subset of patients will they benefit the most. Methods We performed a comprehensive search on topics that assesses antibiotic envelope and implantable cardiac electronic device up until August 2019. Results There were a total of 32,329 subjects from six studies. Antibiotic envelope was associated with a lower risk of major infection with OR 0.42 [0.19, 0.97], P  = .04; I 2 : 58% and HR 0.52 [0.32, 0.85], P  = .009; I 2 : 80%. Upon sensitivity analysis by removing a study, the OR became 0.40 [0.27, 0.59], P   〈  .001; I 2 : 46%. Subgroup analysis for 12 months’ infection was OR 0.65 [0.43, 0.99], P  = .04; I 2 : 49%. Meta‐analysis of propensity‐matched cohort showed a reduced risk of infection with AE (OR of 0.14 [0.05, 0.41], P   〈  .001; I 2 :0%). Mortality was similar in both AE and control groups. Antibiotic envelope reduced the incidence of infection in patients receiving high‐power device (OR 0.44 [0.27, 0.73], P  = .001; I 2 :0%) but not low‐power device. Conclusion Antibiotic envelope (TYRX) was found to be safe and effective in reducing the risk of major infections in high‐risk patients receiving CIED implantation, especially in those receiving high‐power CIED.
    Type of Medium: Online Resource
    ISSN: 1880-4276 , 1883-2148
    URL: Issue
    URL: Article
    DOI: 10.1002/joa3.v36.1
    DOI: 10.1002/joa3.12270
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2696593-8
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  • 10
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    Fibrilasi Atrial dengan Takikardia QRS Lebar
    Indonesian Journal of Cardiology ; 2015
    In:  Indonesian Journal of Cardiology ( 2015-05-08), p. 134-6
    Details
    In: Indonesian Journal of Cardiology, Indonesian Journal of Cardiology, ( 2015-05-08), p. 134-6
    Abstract: Seorang pria Bngladesh, 65 tahun datng ke UGD dengan keluhan mau pingsan. Pasien adalah pasien lama dengan 3VD yang sudah dilakukan revaskularisasi lengkap dengan pemasangan stent. Riwayat medis sebelumnya adalah rawat inap berulang karena ADHF. Hasil ekokardiografi menunjukkan suatu disfungsi ventrikel kiri berat, fraksi ejeksi (EF) 35%, dimensi end diastolik ventrikel kiri (EDD) 66 mm dan dimensi atrium kiri (LAD) 52 mm. Pemeriksaan fisik dalam batas normal.
    Type of Medium: Online Resource
    ISSN: 2620-4762 , 0126-3773
    URL: Article
    DOI: 10.30701/ijc.v35i2.399
    Language: Unknown
    Publisher: Indonesian Journal of Cardiology
    Publication Date: 2015
    detail.hit.zdb_id: 2932484-1
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