In:
Medical review, National Library of Serbia, Vol. 74, No. 3-4 ( 2021), p. 127-133
Abstract:
Introduction. Beta blockers play an essential role in the treatment of
cardiovascular diseases, but also various other endocrinological,
gastroenterological, ophthalmological and neurological disorders. The most
important effects of beta blockers are a reduction in myocardial oxygen
consumption and inhibition of renin secretion. Beta blockers are divided
into three generations according to their selectivity - non-selective,
cardioselective and vasodilating beta blockers. Beta blockers and
obstructive pulmonary diseases. Patients with obstructive pulmonary diseases
are significantly more likely to develop cardiovascular diseases compared to
general population, largely due to common risk factors such as smoking,
systemic inflammation, age, and genetic predisposition. The use of
nonselective beta blockers carries a great risk for patients with
obstructive pulmonary diseases, while cardioselective beta blockers can be
used more extensively. Reversible airway obstruction is predominantly
present in asthma, so that the adverse effects of beta blockers on the
airways are significantly more pronounced in asthma compared to chronic
obstructive pulmonary disease. Conclusion. In both asthma and chronic
obstructive pulmonary disease, the use of highly cardioselective beta
blockers such as bisoprolol and nebivolol is preferred. The use of beta
blockers in patients with asthma requires great caution due to the
possibility of bronchial obstruction, while in patients with chronic
obstructive pulmonary disease they are somewhat safer. Patients must be
closely monitored by a physician, with special attention focused on clinical
signs of airway obstruction such as wheezing, shortness of breath, and
prolonged expiration.
Type of Medium:
Online Resource
ISSN:
0025-8105
,
1820-7383
DOI:
10.2298/MPNS2104129P
Language:
English
Publisher:
National Library of Serbia
Publication Date:
2021
detail.hit.zdb_id:
2381028-2
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