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  • 1
    Online Resource
    Online Resource
    MDPI AG ; 2023
    In:  Metals Vol. 13, No. 3 ( 2023-02-24), p. 468-
    In: Metals, MDPI AG, Vol. 13, No. 3 ( 2023-02-24), p. 468-
    Abstract: Compared with cubic Continuously Variable Crown (CVC), quintic CVC presents integrated control capability of quadratic and quartic crown. In order to take full advantage of quintic CVC and have better comprehensive control of the edge wave, center wave, high order wave and complex wave in practical application, it is necessary to further clarify the complicated profile control characteristics of quintic CVC. In this paper, quintic CVC technology in a 1500 mm continuous hot rolling mill production line has been taken as the research object and use finite element method to study its profile control characteristics. Through finite element simulation, an integrated model of rolls and strip was established to analyze the influence of the shifting, bending force and rolling force on strip profile with different strip widths. Both crown adjustment area and transverse stiffness are gained to study the control capability of quintic CVC. The simulation results show that the positive shifting and positive bending of CVC work roll reduce the quadratic crown and increase the quartic crown, and the controlling effect of shifting on both quadratic and quartic crown is more remarkable than that of bending. The control capability of the crown increases with the increase of strip width. That is, wider strip has a larger crown adjustment area. Meanwhile, there is a strong coupling relationship that the increase of quadratic crown can lead to the decrease of the quartic crown, which is not good for the flexible control of strip profile. With the increase of rolling force, the quadratic crown of strip increases significantly, while the quartic crown does not change obviously. Additionally, the increase of strip width significantly increases the transverse stiffness of mill.
    Type of Medium: Online Resource
    ISSN: 2075-4701
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2662252-X
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  • 2
    In: British Journal of Haematology, Wiley, Vol. 189, No. 3 ( 2020-05), p. 428-437
    Abstract: We explored the relationships between lymphocyte subsets, cytokines, pulmonary inflammation index (PII) and disease evolution in patients with (corona virus disease 2019) COVID‐19. A total of 123 patients with COVID‐19 were divided into mild and severe groups. Lymphocyte subsets and cytokines were detected on the first day of hospital admission and lung computed tomography results were quantified by PII. Difference analysis and correlation analysis were performed on the two groups. A total of 102 mild and 21 severe patients were included in the analysis. There were significant differences in cluster of differentiation 4 (CD4 + T), cluster of differentiation 8 (CD8 + T), interleukin 6 (IL‐6), interleukin 10 (IL‐10) and PII between the two groups. There were significant positive correlations between CD4 + T and CD8 + T, IL‐6 and IL‐10 in the mild group ( r 2  = 0·694, r 2  = 0·633, respectively; P   〈  0·01). After ‘five‐in‐one’ treatment, all patients were discharged with the exception of the four who died. Higher survival rates occurred in the mild group and in those with IL‐6 within normal values. CD4 + T, CD8 + T, IL‐6, IL‐10 and PII can be used as indicators of disease evolution, and the PII can be used as an independent indicator for disease progression of COVID‐19.
    Type of Medium: Online Resource
    ISSN: 0007-1048 , 1365-2141
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 1475751-5
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  • 3
    Online Resource
    Online Resource
    MDPI AG ; 2023
    In:  Metals Vol. 13, No. 2 ( 2023-02-13), p. 385-
    In: Metals, MDPI AG, Vol. 13, No. 2 ( 2023-02-13), p. 385-
    Abstract: The back-up rolls of hot strip mills wear considerably under the conditions of high temperature and heavy load, which affects the roll service period and the stability of strip profile control. Serious uneven wear, short service periods, and spalling problems occurred on conventional back-up rolls of upstream stand CVC mills in 1500 mm continuous hot rolling production lines. Through finite element simulations, the problems are determined to be caused by the configuration of a flat roll contour of the back-up roll and the CVC roll contour of the work roll, which leads to uneven contact pressure between the rolls. The wear distribution form is ‘anti-CVC’ shape, and there is peak contact pressure between the rolls on both sides of the roll body. In particular, the long-term negative shifting of CVC on site further increases the peak contact pressure between the rolls, resulting in uneven wear and spalling accident. Based on the design technology of VCR back-up roll contours with variable contact lengths, and considering the cooperation between the middle of the back-up roll and the CVC work roll contour, the roll contour of the back-up roll has been improved. The designed VCRplus roll contour was analyzed and evaluated by finite element simulation, including the distribution of contact pressure between rolls, the control effect of bending force, and the transverse stiffness of the roll gap. The simulation results show that the VCRplus roll contour can effectively improve the uneven distribution of contact pressure between the rolls, and effectively improve the control effect of bending force and the transverse stiffness of the roll gap. Industrial tests demonstrate that VCRplus back-up roll contours have the advantages of uniform back-up roll wear, enhanced self-sustaining of the roll contour, and further extension of the back-up roll service life. The roll contour has now stably been put into industrial production, and the rolling capacity during the back-up roll service period has been extended from 150,000,000 kg to 250,000,000 kg.
    Type of Medium: Online Resource
    ISSN: 2075-4701
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2662252-X
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  • 4
    In: Blood, American Society of Hematology, Vol. 140, No. Supplement 1 ( 2022-11-15), p. 8468-8469
    Type of Medium: Online Resource
    ISSN: 0006-4971 , 1528-0020
    RVK:
    RVK:
    Language: English
    Publisher: American Society of Hematology
    Publication Date: 2022
    detail.hit.zdb_id: 1468538-3
    detail.hit.zdb_id: 80069-7
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  • 5
    In: International Immunopharmacology, Elsevier BV, Vol. 46 ( 2017-05), p. 56-61
    Type of Medium: Online Resource
    ISSN: 1567-5769
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2017
    detail.hit.zdb_id: 2049924-3
    SSG: 15,3
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  • 6
    In: Iranian Journal of Public Health, Knowledge E DMCC, ( 2020-07-11)
    Abstract: Background: COVID-19(2019 novel coronavirus disease)has brought tremendous pressure to the prevention and control of the national epidemic due to its concealed onset, strong infectivity and fast transmission speed. Methods: In this retrospective study, 226 patients diagnosed with 2019 novel coronavirus pneumonia (NCP) in the Chongqing University Three Gorges Hospital were included. The patients' clinical data, including general information, initial symptoms at the onset, time of disease diagnosis, time to treatment in hospital, time of nucleic acid conversion to negative, disease classification, total time of hospitalization were collected. The clinical data of the mild and severe patients were compared. Results: Fever, cough, sore throat, poor appetite andfatigue were the main symptoms of the diagnosed patients. The time of diagnosis was significantly shorter in the mild patients (4.96 ± 4.10 days) than severe patients (7.63 ± 9.17 days) (P=0.004). Mild patients had shorter time to treatment in hospital (6.09 ± 4.47 vs. 8.71 ± 9.04 days) and less time of nucleic acid conversion to negative (7.58 ± 2.51 vs. 11.6 ± 4.67 days) compared to the severe patients. Conclusion: The above results can be used as a quantitative basis for the “five-early"(early detection, early screening, early diagnosis, early isolation treatment, and early recovery) model. The government, the masses, and the hospitals' joint prevention and optimization of the "five-early" model will provide important scientific reference for further prevention and control of the epidemics.
    Type of Medium: Online Resource
    ISSN: 2251-6093 , 2251-6085
    Language: Unknown
    Publisher: Knowledge E DMCC
    Publication Date: 2020
    detail.hit.zdb_id: 2240935-X
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  • 7
    In: Acupuncture & Electro-Therapeutics Research, Cognizant, LLC
    Abstract: Objective: This study aims to examine the incidence of post-chemotherapy perianal infection and its influencing factors in patients with acute leukemia. 〈 br 〉 Methods: A total of 243 patients with acute leukemia who underwent chemotherapy in the Three Gorges Hospital affiliated to Chongqing University, China, between January 2019 and December 2020 were selected as study subjects. In the present retrospective study, patients with post-chemotherapy perianal infection were monitored, and the perianal infection rate and clinical features of perianal infection were determined. Categorical variables were compared using the Chi-square test, and the influencing factors of post-chemotherapy perianal infection in patients with acute leukemia were evaluated using logistic analysis. 〈 br 〉 Results: A total of 24 patients (9.88%) with acute leukemia suffered post-chemotherapy perianal infection. Age, basic perianal disease (hemorrhoids) history, constipation, diarrhea, duration of agranulocytosis, and length of hospital stay were compared among the patients. Perianal disease classification, perianal ultrasound, colonoscopy, postoperative pathology, and other clinical data were compared and discussed in relation to the occurrence and development of the disease. The results showed that there were no significant differences in perianal infection degrees between genders and among different types of leukemia (p 〉 0.05). There were no statistically significant differences in age, pain score, minimum white blood cell count, deficiency duration, and length of hospital stay among patients with different degrees of infection. The Spearman rank correlation test showed that the perianal infection degree was positively correlated with the highest hypersensitive C-reactive protein (hs-CRP) level (p 〈 0.05). The difference was statistically significant; the higher the maximum hs-CRP/procalcitonin levels, the more serious the perianal infection. 〈 br 〉 Conclusions: Perianal infections are common in the procession of chemotherapy or myelosuppression. This is worthy of clinical recognition. Early recognition of perianal infection and the strengthening of infection risk factor control may be beneficial to improving the subjective feelings of patients with acute leukemia undergoing chemotherapy.
    Type of Medium: Online Resource
    ISSN: 0360-1293
    Language: English
    Publisher: Cognizant, LLC
    Publication Date: 2024
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