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An Overview of Oxygen Reduction Electrocatalysts for Rechargeable Zinc-Air Batteries Enabled by Carbon and Carbon Composites

Zhao, Junkai ; Beijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing 100875 China ; Wei, Daina ; [et al.]

Engineered Science Publisher ; 2021

In: Engineered Science ( 2021)

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In: Engineered Science, Engineered Science Publisher, ( 2021)

Type of Medium: Online Resource

ISSN: 2576-988X , 2576-9898

URL: Article

DOI: 10.30919/es8d420

Language: Unknown

Publisher: Engineered Science Publisher

Publication Date: 2021

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Metagenome-wide analysis uncovers gut microbial signatures and implicates taxon-specific functions in end-stage renal disease

Zhang, Pan ; Wang, Xifan ; Li, Shenghui ; [et al.]

Springer Science and Business Media LLC ; 2023

In: Genome Biology Vol. 24, No. 1 ( 2023-10-12)

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In: Genome Biology, Springer Science and Business Media LLC, Vol. 24, No. 1 ( 2023-10-12)

Abstract: The gut microbiota plays a crucial role in regulating host metabolism and producing uremic toxins in patients with end-stage renal disease (ESRD). Our objective is to advance toward a holistic understanding of the gut ecosystem and its functional capacity in such patients, which is still lacking. Results Herein, we explore the gut microbiome of 378 hemodialytic ESRD patients and 290 healthy volunteers from two independent cohorts via deep metagenomic sequencing and metagenome-assembled-genome-based characterization of their feces. Our findings reveal fundamental alterations in the ESRD microbiome, characterized by a panel of 348 differentially abundant species, including ESRD-elevated representatives of Blautia spp., Dorea spp., and Eggerthellaceae, and ESRD-depleted Prevotella and Roseburia species. Through functional annotation of the ESRD-associated species, we uncover various taxon-specific functions linked to the disease, such as antimicrobial resistance, aromatic compound degradation, and biosynthesis of small bioactive molecules. Additionally, we show that the gut microbial composition can be utilized to predict serum uremic toxin concentrations, and based on this, we identify the key toxin-contributing species. Furthermore, our investigation extended to 47 additional non-dialyzed chronic kidney disease (CKD) patients, revealing a significant correlation between the abundance of ESRD-associated microbial signatures and CKD progression. Conclusion This study delineates the taxonomic and functional landscapes and biomarkers of the ESRD microbiome. Understanding the role of gut microbiota in ESRD could open new avenues for therapeutic interventions and personalized treatment approaches in patients with this condition.

Type of Medium: Online Resource

ISSN: 1474-760X

URL: Article

DOI: 10.1186/s13059-023-03056-y

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2023

detail.hit.zdb_id: 2040529-7

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Wissenschaftspark Albert Einstein

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TH Wildau

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Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity

Han, Junyan ; Zhang, Ning ; Chen, Danying ; [et al.]

Springer Science and Business Media LLC ; 2022

In: Science China Life Sciences Vol. 65, No. 1 ( 2022-01), p. 223-226

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In: Science China Life Sciences, Springer Science and Business Media LLC, Vol. 65, No. 1 ( 2022-01), p. 223-226

Type of Medium: Online Resource

ISSN: 1674-7305 , 1869-1889

URL: Article

DOI: 10.1007/s11427-020-1947-y

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2022

detail.hit.zdb_id: 2546732-3

detail.hit.zdb_id: 2133225-3

SSG: 12

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Hypersensitive Ethylene Signaling and ZMdPG1 Expression Lead to Fruit Softening and Dehiscence

Li, Min ; Zhang, Yanmin ; Zhang, Zongying ; [et al.]

Public Library of Science (PLoS) ; 2013

In: PLoS ONE Vol. 8, No. 3 ( 2013-3-20), p. e58745-

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In: PLoS ONE, Public Library of Science (PLoS), Vol. 8, No. 3 ( 2013-3-20), p. e58745-

Type of Medium: Online Resource

ISSN: 1932-6203

URL: Article

DOI: 10.1371/journal.pone.0058745

DOI: 10.1371/journal.pone.0058745.g001

DOI: 10.1371/journal.pone.0058745.g002

DOI: 10.1371/journal.pone.0058745.g003

DOI: 10.1371/journal.pone.0058745.g004

DOI: 10.1371/journal.pone.0058745.g005

DOI: 10.1371/journal.pone.0058745.g006

DOI: 10.1371/journal.pone.0058745.s001

DOI: 10.1371/journal.pone.0058745.s002

DOI: 10.1371/journal.pone.0058745.s003

DOI: 10.1371/journal.pone.0058745.s004

DOI: 10.1371/journal.pone.0058745.s005

DOI: 10.1371/journal.pone.0058745.s006

DOI: 10.1371/journal.pone.0058745.s007

DOI: 10.1371/journal.pone.0058745.s008

DOI: 10.1371/journal.pone.0058745.s009

DOI: 10.1371/journal.pone.0058745.s010

DOI: 10.1371/journal.pone.0058745.s011

DOI: 10.1371/journal.pone.0058745.s012

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2013

detail.hit.zdb_id: 2267670-3

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Severe acute respiratory infection risk following glucocorticosteroid treatment in uncomplicated influenza-like illness resulting from pH1N1 influenza infection: a case control study

Xing, Xuesen ; Hu, Shixiong ; Chen, Meihua ; [et al.]

Springer Science and Business Media LLC ; 2019

In: BMC Infectious Diseases Vol. 19, No. 1 ( 2019-12)

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In: BMC Infectious Diseases, Springer Science and Business Media LLC, Vol. 19, No. 1 ( 2019-12)

Abstract: Current studies regarding glucocorticosteroid treatment of influenza have only estimated risk of critical illness or death which can be easily confounded by timing of treatment administration. We used severe acute respiratory infection (sARI) as an endpoint and investigated risk associated with receiving glucocorticosteroids before sARI onset. Methods sARI cases were defined as influenza-like illness (ILI) with pH1N1 infection and respiratory distress. Controls were defined as pH1N1 cases other than sARI and randomly selected from the community. We compared glucocorticosteroids and other medications used before sARI onset using a matched case control study adjusted for age group as well as underlying disease. Time-dependent risk and dose responses at different time periods over the course of sARI cases were also examined. Results Of the sARI cases, 34% received glucocorticosteroids before sARI onset compared to 3.8% of controls during equivalent days (OR M-H = 17,95%CI = 2.1–135). Receiving glucocorticosteroids before sARI onset increased risk of developing subsequent critical illness or death (OR M-H = 5.7,95%CI = 1.6–20.2), and the OR M-H increased from 5.7 to 8.5 for continued glucocorticosteroid use after sARI onset. However, only receiving glucocorticosteroids after sARI onset did not increase risk of severe illness (OR M-H = 1.1,95%CI = 0.3–4.6). Each increase in glucocorticosteroids dose of 1 mg/kg/day before sARI onset resulted in an increase of 0.62 ( R 2 = 0.87) in the pMEWS score at the time of sARI onset. Conclusions Early glucocorticosteroid treatment increased risk of sARI and subsequent critical illness or death; however, only receiving glucocorticosteroids after sARI onset did not increase risk of severe illness.

Type of Medium: Online Resource

ISSN: 1471-2334

URL: Article

DOI: 10.1186/s12879-019-4669-9

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2019

detail.hit.zdb_id: 2041550-3

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Wissenschaftspark Albert Einstein

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FH Potsdam

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Transcriptome analysis reveals that PbMYB61 and PbMYB308 are involved in the regulation of lignin biosynthesis in pear fruit stone cells

Zhu, Yansong ; Wang, Yicheng ; Jiang, Huiyan ; [et al.]

Wiley ; 2023

In: The Plant Journal Vol. 116, No. 1 ( 2023-10), p. 217-233

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In: The Plant Journal, Wiley, Vol. 116, No. 1 ( 2023-10), p. 217-233

Abstract: In this study, we used WGCNA with a phylogenetic approach to obtain two candidate MYB TFs. We experimentally validated and characterized candidate transcription factors and revealed a module of PbMYB61 with PbMYB308 regulating PbLAC1 involved in the regulation of pear stone cell biosynthesis. The results presented herein are useful for elucidating the complex mechanisms underlying lignin biosynthesis during pear fruit stone cell development.

Type of Medium: Online Resource

ISSN: 0960-7412 , 1365-313X

URL: Issue

URL: Article

DOI: 10.1111/tpj.v116.1

DOI: 10.1111/tpj.16372

Language: English

Publisher: Wiley

Publication Date: 2023

detail.hit.zdb_id: 2020961-7

SSG: 12

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Analysis of the Postharvest Storage Characteristics of Two New Pear Cultivars ‘Shannongsu’ and ‘Xincixiang’

zhang, Susu ; Qi, Sumin ; Li, Bin ; [et al.]

Elsevier BV ; 2022

In: SSRN Electronic Journal

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In: SSRN Electronic Journal, Elsevier BV

Type of Medium: Online Resource

ISSN: 1556-5068

URL: Article

DOI: 10.2139/ssrn.4239488

Language: English

Publisher: Elsevier BV

Publication Date: 2022

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Analysis of the Postharvest Storage Characteristics of Two New Pear Cultivars ‘Shannongsu’ and ‘Xincixiang’

Zhang, Susu ; Qi, Sumin ; Li, Bin ; [et al.]

MDPI AG ; 2023

In: Horticulturae Vol. 9, No. 2 ( 2023-02-19), p. 281-

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In: Horticulturae, MDPI AG, Vol. 9, No. 2 ( 2023-02-19), p. 281-

Abstract: ‘Shannongsu’ and ‘Xincixiang’ were two new late-ripening pear cultivars with high quality, that were bred by our team. In order to clear the postharvest storage characteristics, mature pears were collected and stored at room temperature. Several fruit characteristics were evaluated over time, such as firmness, ethylene release rate, content of aroma components, softening-related enzyme activity, and gene expression. Both ‘Shannongsu’ and ‘Xincixiang’ were crisp and juicy stored after 60 d at room temperature, which exhibited excellent storage characteristics. The storability may be comprehensive result of low levels of ethylene production, aroma synthesis, softening-related activities, and gene expression. The research cleared the storage characteristics of ‘Shannongsu’ and ‘Xincixiang’ at room temperature for the first time, which will provide scientific theoretical guidance for fruit production and marketing.

Type of Medium: Online Resource

ISSN: 2311-7524

URL: Article

DOI: 10.3390/horticulturae9020281

Language: English

Publisher: MDPI AG

Publication Date: 2023

detail.hit.zdb_id: 2813983-5

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TH Wildau

FH Potsdam

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Analysis of enzymes and phenolic metabolites which affecting the anti-browning property of ‘Shannongsu’ pear

Hou, Xukai ; Liu, Wenjun ; Zuo, Weifang ; [et al.]

Elsevier BV ; 2022

In: LWT Vol. 168 ( 2022-10), p. 113919-

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In: LWT, Elsevier BV, Vol. 168 ( 2022-10), p. 113919-

Type of Medium: Online Resource

ISSN: 0023-6438

URL: Article

DOI: 10.1016/j.lwt.2022.113919

Language: English

Publisher: Elsevier BV

Publication Date: 2022

detail.hit.zdb_id: 1469139-5

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Synthesis of pyrazolone fused benzodiazepines via Rh( iii )-catalyzed [4 + 3] annulation of 1-phenylpyrazolidinones with propargyl alcohols

Zhang, Linghua ; Xu, Yuanshuang ; Zhang, Xiaopeng ; [et al.]

Royal Society of Chemistry (RSC) ; 2020

In: Organic Chemistry Frontiers Vol. 7, No. 16 ( 2020), p. 2284-2290

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In: Organic Chemistry Frontiers, Royal Society of Chemistry (RSC), Vol. 7, No. 16 ( 2020), p. 2284-2290

Type of Medium: Online Resource

ISSN: 2052-4129

URL: Article

DOI: 10.1039/D0QO00657B

Language: English

Publisher: Royal Society of Chemistry (RSC)

Publication Date: 2020

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