In:
SVOA Microbiology, ScienceVolks Limited, Vol. 5, No. 1 ( 2024-2-23), p. 15-21
Abstract:
Given the current disastrous situation of bacterial resistance resulting in deaths worldwide due to the misuse of antibiotics, it is necessary to explore natural means that can reverse this situation. Thus, the essential oil of Astronium urundeuva, which possesses properties directly related to its antibacterial effects, was the focus of this research. The objective was to analyze the antibacterial activity of the essential oil from A. urundeuva leaves, as well as its antibiotic-enhancing action. Initially, approval was obtained from the Biodiversity Authorization and Information Systems (SISBio) and the National System for Management of Genetic Heritage and Associated Traditional Knowledge (SisGen). Subsequently, collections were made, and extracts from A. urundeuva leaves were obtained. In addition, in vitro tests were conducted to determine the minimum inhibitory concentration (MIC) of the essential oil, along with tests to identify any modifying activity on antibiotic action. Bacterial strains such as Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus were used for these tests. It was found through the minimum inhibitory concentration that the essential oil (EO) alone could not prevent bacterial growth, considering that its result was 〉 512 µg/mL. However, it was observed that the essential oil, in conjunction with certain antibiotics, had a potentiating effect on its antibacterial action. The most significant enhancers were Norfloxacin, as it achieved higher action against all three tested strains when combined with the EO, and Gentamicin, which, when combined with the EO, strengthened its action against E. coli and S. aureus. However, Ampicillin, when combined with the EO, showed significance only against S. aureus. Therefore, this study revealed that the essential oil of A. urundeuva may be promising, as it can enhance the action of antibiotics against bacterial growth.
Type of Medium:
Online Resource
ISSN:
2634-534X
DOI:
10.58624/SVOAMB.2024.05.038
Language:
Unknown
Publisher:
ScienceVolks Limited
Publication Date:
2024
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