Format:
1 online resource (345 pages)
Edition:
1st ed.
ISBN:
9789086868391
Content:
This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant's gut microbiota, such as early diet and (postnatal) medical interventions. They further describe the interplay between gut microbiota and functional systems of the body, from the immune system to the central nervous system.The book discusses a range of infant and childhood diseases that are associated with microbial changes or dysbiosis, such as gastrointestinal disorders, allergic diseases, autoimmune disorders and respiratory disorders. Additionally mechanisms by which microbial dysbiosis may influence behaviour in infants are discussed. Other topics include the use of current tools in molecular microbiology for microbiota-related research and clinical practice. In the management of particular paediatric disorders, the potential of microbial manipulation with pre- and probiotics during infancy and childhood is increasingly being investigated. This book presents the evidence supporting their use in practice and reviews safety aspects.Microbiota in health and disease: from pregnancy to childhood has the ambition to provide the reader with an overview of the most recent and stunning advances in the field of infant and child microbiota and their role in health, disease and prevention. As such, it is an excellent resource for health care professionals, students and researchers in the field of life sciences.
Content:
Intro -- Table of contents -- Part I. The 'healthy' infant gut microbiota -- Chapter 1 Infant and child microbiota: current status and directions for future research -- P.D. Browne1,2,3*, M.B. Van der Waal2,3 and E. Claassen2 -- Abstract -- 1.1 Introduction -- 1.2 The infant and child microbiota -- 1.3 Factors influencing the gut microbiota development -- 1.4 Intestinal microbiota and physiological systems and it's role in paediatric diseases -- 1.5 From bowel to infant behaviour -- 1.6 Consequences of dysbiosis outside of the gut -- 1.7 Assessment of microbiota -- 1.8 Manipulating the gut microbiota -- 1.9 Conclusions -- References -- Part II. Factors influencing the gut microbiota development -- Chapter 2 Development of the neonatal microbiota -- G.R. Young1, S. Zalewski2, S.P. Cummings3 and C. Lanyon1* -- Abstract -- 2.1 Acquisition of initial gastrointestinal microbiota -- 2.2 Symbiosis and dysbiosis -- 2.3 Disease states and the microbiota -- 2.4 Management strategies and microbiota associated disease -- 2.5 Future research -- References -- Chapter 3 Impact of maternal prenatal psychosocial stress and maternal obesity on infant microbiota -- P.D. Browne1,2*, E. Van den Berg3 and C. De Weerth1 -- Abstract -- 3.1 Introduction -- 3.2 Early life programming -- 3.3 Maternal prenatal psychosocial stress -- 3.4 Maternal pregnancy obesity -- 3.5 Conclusions -- References -- Chapter 4 The impact of birth and postnatal medical interventions on infant gut microbiota -- A.L. Kozyrskyj1*, S.L. Bridgman1 and M.H. Tun2 -- Abstract -- 4.1 Introduction -- 4.2 Caesarean section delivery -- 4.3 Maternal intrapartum antibiotics -- 4.5 Hospitalisation post birth -- 4.6 Infant postnatal antibiotics -- 4.7 Conclusions -- References -- Appendix 4.1 Study details of infant gut microbial dysbiosis by medical intervention type and taxon category.
Note:
Description based on publisher supplied metadata and other sources
Additional Edition:
9789086862948
Additional Edition:
Erscheint auch als Druck-Ausgabe 9789086862948
Language:
English
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