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  • 1
    Online Resource
    Online Resource
    [Erscheinungsort nicht ermittelbar] : Alma Mater Studiorum - Università di Bologna
    UID:
    (DE-627)1802824030
    Content: I pazienti con glomerulopatie con sindrome nefrosica hanno poche opzioni di trattamento efficace. Riportiamo la nostra esperienza sull'utilizzo della fotochemioterapia extracorporea ( ECP) in 9 pazienti in cui non era stata osservata una risposta efficace/duratura alla convenzionale terapia farmacologica. L'ECP è una promettente terapia immunomodulante, che è stata utilizzata con successo nel trattamento di altre condizioni immunomediate come il rigetto nel trapianto e il GvHD. METODI: In questo studio abbiamo arruolato 9 pazienti, 5 maschi e 4 femmine, età media 32.7±8.9 anni, affetti da sindrome nefrosica e non responsivi/resistenti alle comuni terapie. Il follow-up medio è stato di 41.3±21.7 mesi. Tutti i pazienti sono stati sottoposti a cicli di fotochemioterapia extracorporea secondo il seguente schema: 1ciclo (2 sedute in 2 giorni consecutivi) ogni 15 giorni per tre mesi, seguito da 1ciclo al mese per tre mesi. Il follow up è stato effetuatio ogni 3 mesi durante il primo anno e poi ogni 12 mesi. Durante il follow up sono stati monitorati pressione arteriosa, funzione renale, marcatori diretti ed indiretti di attività della malattia e indici di flogosi. RISULTATI: attraverso l'analisi dei parametri ematochimici indici di attività di malattia, e monitorando l'eventuale progressione della malattia renale, è stato possibile dimostrare che l' ECP può rappresentare per casi selezionati di pazienti una valida ulteriore opzione terapeutica. Secondo i risultati preliminari tale trattamento risulta inoltre caratterizzato da un eccellente profilo di sicurezza . CONCLUSIONI: I risultati osservati suggeriscono che l'ECP è un trattamento efficace per i pazienti con glomenulonefriti con sindrome nefrosica, soprattutto in coloro che presentano ancora una buona funzionalità renale. Valutazioni cliniche aggiuntive dovranno aiuteranno a definire meglio la popolazione di pazienti in cui ECP sia più efficace e raccomandabile. ; Patients with glomerulopathies associated with nephrotic syndrome have few effective treatment options. Here we report on the use of extracorporeal photochemotherapy (ECP) in 9 patients in whom glomerulopathy failed to respond to pharmacologic therapy. ECP is a promising immunomodulatory therapy associated with few side effects, that has been successfully used in the treatment of other immune-mediated conditions such as solid organ transplant rejection and graft-versus-host disease. METHODS: In this study, we enrolled 9 patients, 5 males and 4 females, mean age 32.7±8.9 years, suffering from nephrotic syndrome. The mean follow-up was 41.3±21.7 months. All patients were subjected to cycles of extracorporeal photochemotherapy according to the following scheme: 1 cycle (2 sessions on 2 consecutive days) every 15 days for three months, followed by 1 cycle per month for three months. The follow-up was performed every 3 months during the first year and then every 12 months. during follow-up were monitored blood pressure, renal function, indirect markers of disease activity and phlogosis indexes. RESULTS: through the analysis of blood chemistry parameters markers of disease activity, and by monitoring eventual progression of chronic kidney disease, it has been possible to show that the ECP may represent for selected cases of patients a viable additional option. This treatment also would be, according to preliminary results, characterized by an excellent safety profile. CONCLUSIONS: The results suggest that ECP is a feasible treatment for patients with glomerulopathies associated with nephrotic syndrome who have adequate baseline renal function. Additional clinical evaluation will have to be performed to better define the patient population in which ECP is most effective.
    Note: Dissertation Alma Mater Studiorum - Università di Bologna 2014
    Language: Italian
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  • 2
    UID:
    (DE-604)BV038053961
    ISBN: 88-7970-044-8
    In: pages:39-45
    In: Il restauro della Locanda a Pratolino / Scuola Professionale Edile di Firenze. A cura di Luigi Zangheri, Firenze, 1996, S. 39-45, 88-7970-044-8
    Language: Italian
    Keywords: Parco Mediceo ; Restaurierung ; Geschichte 1989-1993
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  • 3
    UID:
    (DE-604)BV039516973
    Format: viii, 333 p. , ill. (some col.) , 21 cm
    ISBN: 9788870966305
    Note: Includes bibliographical references
    Language: Italian
    Keywords: Toscanini, Arturo 1867-1957 ; Aufsatzsammlung
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  • 4
    UID:
    (DE-604)BV038948931
    Format: 143 S. , Ill. , 27 cm
    ISBN: 8881250926
    Series Statement: Manuali di assistenza tecnica 25 : Tecnologie, materiali, cornici
    Language: Italian
    Keywords: Bauornament ; Kunststein ; Baudenkmal
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  • 5
    UID:
    (DE-604)BV037681187
    Format: 47 S. , zahlr. Ill. , 24 cm
    Edition: 1. ed.
    ISBN: 9788889999479 , 8889999470
    Language: Italian
    Keywords: Cavallini, Marco 1946-
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  • 6
    UID:
    (DE-604)BV038874109
    Format: 180 S. , graph. Darst., Ill.
    ISBN: 8881254158
    Series Statement: Manuali / Università Internazionale dell'Arte 〈Firenze; Venezia〉 46 : tecnologie, materiali, colori
    Language: Italian
    Keywords: Steinschneidekunst ; Kunststein ; Steinbearbeitung
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  • 7
    UID:
    (DE-101)1197454896
    Format: Online-Ressource , online resource.
    ISSN: 1436-2813 , 1436-2813
    In: volume:31
    In: number:3
    In: pages:277-279
    In: date:3.2001
    In: Surgery today, Tokyo : Springer, 1971-, 31, Heft 3, 277-279, 3.2001, 1436-2813
    Language: English
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  • 8
    UID:
    (DE-101)1050119118
    Format: 2 CDs , Beil. , 12 cm
    Note: P-Jahr: 2013.
    Language: German
    Keywords: CD
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  • 9
    Online Resource
    Online Resource
    Hauppauge : Nova Science Publishers, Incorporated
    UID:
    (DE-627)1041589379
    Format: 1 Online-Ressource (118 pages)
    ISBN: 9781536100235
    Series Statement: Hospitality, Tourism and Marketing Studies
    Content: Intro -- Contents -- Preface -- List of Figures -- List of Tables -- Chapter 1 -- Introduction on Tourism in Europe and in the Italy-France Cross-Border Area -- Abstract -- Tourism Impact on European Economy -- Reflections on the Impact of EU Policy on Tourism, and on the Maritime and Coastal Tourism -- Conclusive Remarks on Tourism Competitiveness in the Italy - France Cross-Border Area -- References -- Chapter 2 -- Objectives and Methodology of the ART2 Project for Tourism Competitiveness -- Abstract -- Introduction -- Methods -- Participants -- Background and Objectives -- Methodology -- Organisation of the Project -- Organisation Structure -- Execution Activities -- Conclusion -- References -- Map of the Scientific Competences on Tourism and in the Priority Sectors in the Italy-France Cross-Border Area -- Abstract -- Introduction -- Methods -- General Approach -- Undergraduate, Graduate, Post-Graduate Courses, and Professionals Course -- Research Activities -- Strategic Projects -- Results -- General Approach about Results on Undergraduate, Graduate, Post-Graduate Courses, and Professionals Course -- Corsica -- Sardinia -- Liguria -- Tuscany -- Research Centres and Activities -- Strategic Projects -- Conclusion -- References -- Chapter 4 -- European Funds and Opportunities for Tourism Competitiveness Through Synergies with the Priority Sectors -- Abstract -- Introduction -- Methods -- Recognition of Funding for Tourism -- Horizon 2020 -- COSME -- LIFE Programme -- Creative Europe -- Erasmus + -- EaSI -- European Regional Development Fund (ERDF) -- European Social Fund (ESF) -- European Agriculture Fund for Rural Development (EAFRD) -- European Maritime and Fisheries Fund (EMFF) -- Results -- The Existing New Opportunities in Cross-Border Regions -- Conclusion -- References -- Chapter 5
    Content: Conclusions about the Network of Priority Sectors for the Competitiveness of Cross-Border Tourism -- Abstract -- Introduction -- Methods -- Results -- Conclusion -- References -- About the Authors -- Index
    Additional Edition: 9781634850285
    Additional Edition: Erscheint auch als Druck-Ausgabe Cavallini, Iacopo Tourism Competitiveness in the Italy-France Cross-Border Area: The Role of Knowledge and Innovation Transfer Hauppauge : Nova Science Publishers, Incorporated,c2017 9781634850285
    Language: English
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  • 10
    UID:
    (DE-627)881786535
    Format: 1 Online-Ressource
    Edition: Online-Ausg.
    Series Statement: Hospitality, tourism and marketing studies
    Content: Introduction on tourism in Europe and in the cross-border Italy-France -- Objectives and methodology of the ART Project for the Tourism Competitiveness -- Map of the scientific competences on tourism and in the priority sectors in the Italy-France cross-border area -- European funds and opportunities for the tourism competitiveness through synergies with the priority sectors -- Conclusions about the network of priority sectors for the competitiveness of cross-border tourism
    Note: Includes index
    Additional Edition: 1536100234
    Additional Edition: 9781634850285
    Additional Edition: 9781536100235
    Additional Edition: Erscheint auch als Druck-Ausgabe Cavallini, Iacopo, author Tourism competitiveness in the Italy-France cross-border area Hauppauge, New York : Nova Science Publishers, Inc., 2016
    Language: English
    URL: Volltext  (lizenzpflichtig)
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