Format:
Online-Ressource
ISSN:
2192-6549
Content:
Abstract: The total synthesis of the non‐peptide fibrinogen receptor antagonists, sibrafiban (1) (Ro 48–3657) and lamifiban (2) (Ro 44–9883), is described. Both contain 4‐hydroxypiperidine unit and the same solid‐phase synthesis method was used as a key step. Connection of a secondary alcohol to the DHP‐resin, followed by iterative saponification and coupling sequences, provided novel drugs.
In:
volume:48
In:
number:2
In:
year:2013
In:
pages:133-135
In:
extent:3
In:
Zhongguo-Huaxuehui 〈Taiwan〉, Journal of the Chinese Chemical Society, Malden, Mass. : Wiley-Blackwell, 1954-, 48, Heft 2 (2013), 133-135 (gesamt 3), 2192-6549
Language:
English
DOI:
10.1002/jccs.200100024
URN:
urn:nbn:de:101:1-2023102505501371867663
URL:
https://doi.org/10.1002/jccs.200100024
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023102505501371867663
URL:
https://d-nb.info/1307183484/34
URL:
https://doi.org/10.1002/jccs.200100024
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