Format:
Online-Ressource (686 p.)
Edition:
Online-Ausg. Electronic reproduction; Mode of access: World Wide Web
ISBN:
9783527318209
,
3527623116
,
1281947121
,
9783527623112
,
9781281947123
Content:
Edited by one of the main driving forces behind the field's momentous rise in recent years, this one-stop reference is the first comprehensive resource to integrate recent advances. The first part addresses biochemical aspects and applications, the second and third parts are devoted to compounds with therapeutic potential, with the third part focusing on newly introduced anticancer nucleoside drugs. Essential reading for every scientist working in this area.
Content:
Edited by one of the main driving forces behind the field's momentous rise in recent years, this one-stop reference is the first comprehensive resource to integrate recent advances.The first part addresses biochemical aspects and applications, the second and third parts are devoted to compounds with therapeutic potential, with the third part focusing on newly introduced anticancer nucleoside drugs.Essential reading for every scientist working in this area
Note:
Description based upon print version of record
,
Modified Nucleosides; Contents; Preface; List of Contributors; Part I Biochemistry and Biophysics; 1 Investigations on Fluorine-Labeled Ribonucleic Acids by (19)F NMR Spectroscopy; 2 8-Oxo-7,8-Dihydro-2´-Deoxyguanosine: A Major DNA Oxidation Product; 3 Modified DNA Bases: Probing Base-Pair Recognition by Polymerases; 4 2´-Deoxyribose-Modified Nucleoside Triphosphates and their Recognition by DNA Polymerases; 5 Pyrimidine Dimers: UV-Induced DNA Damage; 6 Locked Nucleic Acids: Properties, Applications, and Perspectives
,
7 Synthesis and Properties of Oligonucleotides Incorporating Modified Nucleobases Capable of Watson-Crick-Type Base-Pair Formation8 The Properties of 4´-Thionucleosides; 9 S-Adenosyl-L-methionine and Related Compounds; Part II Biotechnology; 10 5-Substituted Nucleosides in Biochemistry and Biotechnology; 11 Universal Base Analogues and their Applications to Biotechnology; Part III Medicinal Chemistry; 12 The Properties of Locked Methanocarba Nucleosides in Biochemistry, Biotechnology, and Medicinal Chemistry
,
13 Synthesis, Chemical Properties and Biological Activities of Cyclic Bis(3´-5´)diguanylic Acid (c-di-GMP) and its Analogues14 Siderophore Biosynthesis Inhibitors; 15 Synthesis and Biological Activity of Selected Carbocyclic Nucleosides; 16 4´-C-Ethynyl-2´-Deoxynucleosides; 17 Modified Nucleosides as Selective Modulators of Adenosine Receptors for Therapeutic Use; 18 The Design of Forodesine HCl and Other Purine Nucleoside Phosphorylase Inhibitors; 19 Formycins and their Analogues: Purine Nucleoside Phosphorylase Inhibitors and their Potential Application in Immunosuppression and Cancer
,
20 1-(3-C-Ethynyl-ß-D-ribo-pentofuranosyl)cytosine (ECyd)21 Syntheses and Biological Activity of Neplanocin and Analogues; 22 Clitocine and Its Analogues; Part IV Antitumorals and Antivirals; 23 Capecitabine Preclinical Studies: From Discovery to Translational Research; 24 Tenofovir and Adefovir as Antiviral Agents; 25 Clofarabine: From Design to Approval; Index;
,
Electronic reproduction; Mode of access: World Wide Web
Additional Edition:
9783527623129
Additional Edition:
3527623124
Additional Edition:
9783527623129
Additional Edition:
3527318208
Additional Edition:
9783527318209
Additional Edition:
Print version Modified Nucleosides in Biochemistry, Biotechnology and Medicine
Language:
English
Keywords:
Electronic books
DOI:
10.1002/9783527623112
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