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  • 1
    Online Resource
    Online Resource
    Modeling and control of infectious diseases in the host : with Matlab and R (2019)
    London ; San Diego, CA : Academic Press
    Details
    UID:
    (DE-602)b3kat_BV046623371
    Format: 1 online resource ( xiii, 242 pages.)
    ISBN: 9780128131114 , 012813111X
    Note: Description based on print version record
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9780128130520
    Additional Edition: ISBN 0128130520
    Additional Edition: ebook version ISBN 9780128131114
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Charité
    KOBV
  • 2
    Online Resource
    Online Resource
    Feedback control for personalized medicine (2022)
    London, UK : Academic Press | [Amsterdam] : Elsevier ScienceDirect
    Details
    UID:
    (DE-603)501267166
    ISBN: 9780323906654 , 0323906656
    Note: Includes index
    Additional Edition: 9780323901710
    Language: English
    URL: https://www.sciencedirect.com/science/book/9780323901710
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    HeBIS
  • 3
    Online Resource
    Online Resource
    Modeling and control of infectious diseases in the host : with Matlab and R (2019)
    London ; San Diego, CA : Academic Press
    Details
    UID:
    (DE-604)BV046623371
    Format: 1 online resource ( xiii, 242 pages.)
    ISBN: 9780128131114 , 012813111X
    Note: Description based on print version record
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9780128130520
    Additional Edition: ISBN 0128130520
    Additional Edition: ebook version ISBN 9780128131114
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Charité
    BVB
  • 4
    Online Resource
    Online Resource
    Feedback control for personalized medicine (2022)
    London, UK : Academic Press
    Details
    UID:
    (DE-627)1833030079
    Format: 1 Online-Ressource
    ISBN: 9780323906654 , 0323906656
    Note: Includes index , Front Cover -- Feedback Control for Personalized Medicine -- Copyright -- Contents -- Contributors -- About the editor -- Preface -- Acknowledgments -- 1 Closing the loop in personalized medicine -- References -- 2 Optimal control strategies to tailor antivirals for acute infectious diseases in the host: a study case of COVID-19 -- 2.1 Introduction -- 2.1.1 Notation -- 2.2 Review of the target cell limited model for in-host infection -- 2.3 Equilibrium characterization and stability -- 2.3.1 Asymptotic stability of the equilibrium sets -- 2.3.2 Stability theory , 2.6.3 Quasioptimal single interval treatment -- 2.6.4 Short-term treatment -- 2.6.5 Two-step treatment, lowering the peak of V -- 2.7 Conclusions and future works -- References -- 3 Input-output approaches for personalized drug dosing of antibiotics -- 3.1 Introduction -- 3.2 Population pharmacokinetic model -- 3.2.1 State-space representation -- 3.2.2 System analysis -- 3.2.3 Case study: model of meropenem -- 3.3 Individualized drug dosing -- 3.3.1 Input-output analysis -- 3.3.2 Input-output formula for drug dosing -- 3.3.3 ``Worst-case'' analysis -- 3.3.4 PTA analysis , 4.5.3 The switching signal -- 4.5.4 Coupling the safety layer with the offset-free strategy -- 4.6 Conclusion -- References -- 5 Deep neuronal network-based glucose prediction for personalized medicine -- 5.1 Introduction -- 5.2 Deep neural networks -- 5.2.1 Recurrent neuronal networks -- 5.2.2 Long short-term memory recurrent neural network -- 5.2.3 Bidirectional LSTM -- 5.2.4 Multilayer networks -- 5.3 Direct multistep ahead prediction strategy -- 5.4 System description -- 5.4.1 Dataset description -- 5.4.2 Neuronal network configuration using CGM -- 5.5 Results -- 5.6 Conclusion and discussion
    Additional Edition: 0323901719
    Additional Edition: Erscheint auch als Online-Ausgabe 9780323906654
    Additional Edition: Erscheint auch als 0323901719
    Additional Edition: 9780323901710
    Language: English
    URL: lizenzpflichtig
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    GBV
  • 5
    Online Resource
    Online Resource
    Modeling and control of infectious diseases in the host : with MATLAB and R (2019)
    London : Elsevier AP Academic Press
    Details
    UID:
    (DE-605)HT020030551
    Format: 1 Online-Ressource (xiii, 243 Seiten) , Illustrationen
    ISBN: 9780128131114
    Additional Edition: Erscheint auch als Druck-Ausgabe 9780128130520
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    HBZ
  • 6
    Book
    Book
    Modeling and control of infectious diseases in the host : with MATLAB and R (2019)
    [Amsterdam] : Elsevier
    Details
    UID:
    (DE-603)446776009
    Format: xiii, 242 Seiten , Illustrationen, Diagramme
    ISBN: 9780128130520
    Note: Literaturverzeichnis Seite 221-235
    Language: English
    Subjects: Mathematics
    RVK:
    SK 950
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    HeBIS
  • 7
    Online Resource
    Online Resource
    Feedback Control for Personalized Medicine (2022)
    San Diego : Elsevier Science & Technology
    Details
    UID:
    (DE-627)1800554974
    Format: 1 online resource (248 pages)
    ISBN: 9780323906654
    Content: Front Cover -- Feedback Control for Personalized Medicine -- Copyright -- Contents -- Contributors -- About the editor -- Preface -- Acknowledgments -- 1 Closing the loop in personalized medicine -- References -- 2 Optimal control strategies to tailor antivirals for acute infectious diseases in the host: a study case of COVID-19 -- 2.1 Introduction -- 2.1.1 Notation -- 2.2 Review of the target cell limited model for in-host infection -- 2.3 Equilibrium characterization and stability -- 2.3.1 Asymptotic stability of the equilibrium sets -- 2.3.2 Stability theory -- 2.3.3 Attractivity of set Xsst -- 2.3.4 Local ε-δ stability of Xsst -- 2.3.5 Asymptotic stability of Xsst -- 2.3.6 U∞ as a function of initial conditions -- 2.3.7 Simulation example -- 2.4 Inclusion of PK and PD of antiviral treatment -- 2.4.1 Impulsive scheme -- 2.4.2 Simulation example -- 2.5 Control strategies to tailor therapies -- 2.5.1 First control objective: maximizing the final value of the uninfected cells -- 2.5.2 Second control objective: minimizing the virus peak -- 2.6 Simulation results -- 2.6.1 Strong long-term treatment. Virus rebound -- 2.6.2 Soft long-term treatment -- 2.6.3 Quasioptimal single interval treatment -- 2.6.4 Short-term treatment -- 2.6.5 Two-step treatment, lowering the peak of V -- 2.7 Conclusions and future works -- References -- 3 Input-output approaches for personalized drug dosing of antibiotics -- 3.1 Introduction -- 3.2 Population pharmacokinetic model -- 3.2.1 State-space representation -- 3.2.2 System analysis -- 3.2.3 Case study: model of meropenem -- 3.3 Individualized drug dosing -- 3.3.1 Input-output analysis -- 3.3.2 Input-output formula for drug dosing -- 3.3.3 ``Worst-case'' analysis -- 3.3.4 PTA analysis -- 3.3.5 Drawbacks and advantages of the I/O approach -- 3.4 State estimation and feedback control law -- 3.5 Conclusion.
    Note: Description based on publisher supplied metadata and other sources
    Additional Edition: 9780323901710
    Additional Edition: Erscheint auch als Druck-Ausgabe 9780323901710
    Language: English
    URL: lizenzpflichtig
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    BSZ
    GBV
  • 8
    Online Resource
    Online Resource
    Feedback control for personalized medicine (2022)
    London, UK : Academic Press
    Details
    UID:
    (DE-627)1827632003
    Format: 1 Online-Ressource
    ISBN: 0323906656
    Note: Includes index , Front Cover -- Feedback Control for Personalized Medicine -- Copyright -- Contents -- Contributors -- About the editor -- Preface -- Acknowledgments -- 1 Closing the loop in personalized medicine -- References -- 2 Optimal control strategies to tailor antivirals for acute infectious diseases in the host: a study case of COVID-19 -- 2.1 Introduction -- 2.1.1 Notation -- 2.2 Review of the target cell limited model for in-host infection -- 2.3 Equilibrium characterization and stability -- 2.3.1 Asymptotic stability of the equilibrium sets -- 2.3.2 Stability theory , 2.6.3 Quasioptimal single interval treatment -- 2.6.4 Short-term treatment -- 2.6.5 Two-step treatment, lowering the peak of V -- 2.7 Conclusions and future works -- References -- 3 Input-output approaches for personalized drug dosing of antibiotics -- 3.1 Introduction -- 3.2 Population pharmacokinetic model -- 3.2.1 State-space representation -- 3.2.2 System analysis -- 3.2.3 Case study: model of meropenem -- 3.3 Individualized drug dosing -- 3.3.1 Input-output analysis -- 3.3.2 Input-output formula for drug dosing -- 3.3.3 ``Worst-case'' analysis -- 3.3.4 PTA analysis , 4.5.3 The switching signal -- 4.5.4 Coupling the safety layer with the offset-free strategy -- 4.6 Conclusion -- References -- 5 Deep neuronal network-based glucose prediction for personalized medicine -- 5.1 Introduction -- 5.2 Deep neural networks -- 5.2.1 Recurrent neuronal networks -- 5.2.2 Long short-term memory recurrent neural network -- 5.2.3 Bidirectional LSTM -- 5.2.4 Multilayer networks -- 5.3 Direct multistep ahead prediction strategy -- 5.4 System description -- 5.4.1 Dataset description -- 5.4.2 Neuronal network configuration using CGM -- 5.5 Results -- 5.6 Conclusion and discussion
    Additional Edition: 9780323906654
    Additional Edition: 9780323901710
    Additional Edition: 0323901719
    Additional Edition: Erscheint auch als Online-Ausgabe 9780323906654
    Additional Edition: Erscheint auch als 0323901719
    Additional Edition: 9780323901710
    Language: English
    URL: lizenzpflichtig
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    BSZ
  • 9
    Book
    Book
    Modeling and control of infectious diseases in the host : with MATLAB and R (2019)
    London, United Kingdom : Academic Press, an imprint of Elsevier
    Details
    UID:
    (DE-627)1663082707
    Format: xiii, 242 Seiten , Illustrationen
    ISBN: 9780128130520
    Series Statement: Engineering
    Note: Literaturangaben
    Language: English
    Keywords: Programm
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    GBV
  • 10
    Online Resource
    Online Resource
    Modeling and Control of Infectious Diseases in the Host : With MATLAB and R (2019)
    London, United Kingdom : Academic Press, an imprint of Elsevier
    Details
    UID:
    (DE-627)1734930306
    Format: 1 Online-Ressource
    ISBN: 012813111X , 9780128131114
    Content: Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R
    Content: Mathematical Modeling Principles --Model Parameter Estimation --Modeling Influenza Virus Infection --Modeling Ebola Virus Infection --Modeling HIV Infection --HIV Evolution During Treatment --Optimal Therapy Scheduling --Suboptimal Therapy Scheduling --PK/PD-based Impulsive Control --Bibliography --Index.
    Note: Includes bibliographical references and index
    Additional Edition: 9780128130520
    Additional Edition: 0128130520
    Additional Edition: 9780128131114
    Additional Edition: 9780128130520
    Additional Edition: 0128130520
    Additional Edition: Erscheint auch als Druck-Ausgabe 9780128130520
    Additional Edition: 0128130520
    Additional Edition: ebook version 9780128131114
    Language: English
    Keywords: Electronic books
    URL: lizenzpflichtig
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    BSZ
    GBV
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