Format:
Online-Ressource
ISSN:
1099-0690
Content:
Abstract: The first transition‐metal‐catalyzed cross‐coupling reactions of 2,3,5‐tribromo‐1H‐inden‐1‐one are reported. The Suzuki–Miyaura reaction of 2,3,5‐tribromo‐1H‐inden‐1‐one with three equivalents of arylboronic acid gave 2,3,5‐triaryl‐1H‐inden‐1‐ones. The reaction with one and two equivalents of arylboronic acid gave 2,5‐dibromo‐3‐aryl‐1H‐inden‐1‐ones and 5‐bromo‐2,3‐diaryl‐1H‐inden‐1‐ones, respectively, with very good site‐selectivity. The one‐pot reaction of 2,3,5‐tribromo‐1H‐inden‐1‐one with one equivalent of two different arylboronic acids afforded 5‐bromo‐2,3‐diaryl‐1H‐inden‐1‐ones containing two different terminal aryl groups. Other one‐pot reactions allowed the synthesis of 2,3,5‐triaryl‐1H‐inden‐1‐ones containing different aryl groups.
In:
volume:2011
In:
number:22
In:
year:2011
In:
pages:4212-4221
In:
extent:10
In:
European journal of organic chemistry, Weinheim : Wiley-VCH Verl., 1998-, 2011, Heft 22 (2011), 4212-4221 (gesamt 10), 1099-0690
Language:
English
DOI:
10.1002/ejoc.201100313
URN:
urn:nbn:de:101:1-2023032006073424457643
URL:
https://doi.org/10.1002/ejoc.201100313
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023032006073424457643
URL:
https://d-nb.info/1283853728/34
URL:
https://doi.org/10.1002/ejoc.201100313
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