Format:
Online-Ressource
ISSN:
1521-3773
Content:
Abstract: Activatable fluorescent and chemiluminescent dyes with near‐infrared emission have indispensable roles in the fields of bioimaging, molecular prodrugs, and phototheranostic agents. As one of the most popular fluorophore scaffolds, the dicyanomethylene‐4H‐pyran scaffold has been applied to fabricate a large number of versatile activatable optical dyes for analytes detection and diseases diagnosis and treatment by virtue of its high photostability, large Stokes shift, considerable two‐photon absorption cross‐section, and structural modifiability. This review discusses the molecular design strategies, recognition mechanisms, and both in vitro and in vivo bio‐applications (especially for diagnosis and therapy of tumors) of activatable dicyanomethylene‐4H‐pyran dyes. The final section describes the current shortcomings and future development prospects of this topic.
In:
day:06
In:
month:11
In:
year:2023
In:
extent:17
In:
Angewandte Chemie / International edition, Weinheim : Wiley-VCH, 1962-, (06.11.2023) (gesamt 17), 1521-3773
Language:
English
DOI:
10.1002/anie.202311764
URN:
urn:nbn:de:101:1-2023110714173445456262
URL:
https://doi.org/10.1002/anie.202311764
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023110714173445456262
URL:
https://d-nb.info/1308999402/34
URL:
https://doi.org/10.1002/anie.202311764
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