Format:
Online-Ressource
ISSN:
1099-0690
Content:
Abstract: The stereoselective synthesis of the three major fragments (C1–C9, C10–C17, and C19–C26) of an antimitotic marine macrolide, (–)‐dictyostatin, has been achieved with a desymmetrization strategy and Oppolzer syn and anti aldol protocols as the key reactions. Takai olefination and Sonogashira coupling reactions were successfully utilized to establish the 2Z,4E‐dienoate portion of the C1–C9 fragment and Stille coupling for the Z‐diene core of C19–C26.
In:
volume:2010
In:
number:11
In:
year:2010
In:
pages:2148-2156
In:
extent:9
In:
European journal of organic chemistry, Weinheim : Wiley-VCH Verl., 1998-, 2010, Heft 11 (2010), 2148-2156 (gesamt 9), 1099-0690
Language:
English
DOI:
10.1002/ejoc.200901448
URN:
urn:nbn:de:101:1-2023060504550622596818
URL:
https://doi.org/10.1002/ejoc.200901448
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023060504550622596818
URL:
https://d-nb.info/1292050535/34
URL:
https://doi.org/10.1002/ejoc.200901448
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