Format:
Online-Ressource (XVI, 198 p. 33 illus., 20 illus. in color, online resource)
ISBN:
9783709106877
Series Statement:
SpringerLink
Content:
This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson`s disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders
Note:
Includes bibliographical references and index
,
1. Historical Review2. Epidemiology -- 3. Neuropathology -- 4. Etiopathogenesis -- 5. Animal Models -- 6. Clinical Presentation -- 7. Clinical diagnostic Criteria -- 8. Natural History -- 9. Investigations -- 10. Tratment.
Additional Edition:
9783709106860
Additional Edition:
Erscheint auch als Druck-Ausgabe Multiple system atrophy Wien : Springer, 2014 9783709106860
Language:
English
Subjects:
Medicine
Keywords:
Multisystematrophie
DOI:
10.1007/978-3-7091-0687-7
URL:
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