Format:
Online-Ressource
ISSN:
1099-0690
Content:
Abstract: A telescoped sequence involving palladium‐catalysed intramolecular enolate arylation followed by an in situ HWE olefination has been developed to provide rapid access to 3‐alkenyl‐oxindoles. This “one‐pot” process, which is greatly accelerated by microwave irradiation, proceeds with low loadings of palladium (II) acetate (0.2–1.0 mol‐%), and has been used to prepare a range of adducts derived from aromatic, heteroaromatic and aliphatic aldehydes as well as formaldehyde. In addition, further elaboration of the formaldehyde adducts are described. The applicability of the process has been established by carrying out the first synthesis of Soulieotine, a constituent of a traditional Chinese medicine. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
In:
volume:2009
In:
number:18
In:
year:2009
In:
pages:2947-2952
In:
extent:6
In:
European journal of organic chemistry, Weinheim : Wiley-VCH Verl., 1998-, 2009, Heft 18 (2009), 2947-2952 (gesamt 6), 1099-0690
Language:
English
DOI:
10.1002/ejoc.200900294
URN:
urn:nbn:de:101:1-2023041605094104042606
URL:
https://doi.org/10.1002/ejoc.200900294
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023041605094104042606
URL:
https://d-nb.info/1286352959/34
URL:
https://doi.org/10.1002/ejoc.200900294
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