Format:
1 Online-Ressource (16 Seiten)
ISSN:
2314-6141
Content:
The Sonic Hedgehog (SHH) pathway plays a central role in the developing mammalian CNS. In our study, we aimed to investigate the spatiotemporal SHH pathway expression pattern in human fetal brains. We analyzed 22 normal fetal brains for Shh, Patched, Smoothened, and Gli1-3 expression by immunohistochemistry. In the telencephalon, strongest expression of Shh, Smoothened, and Gli2 was found in the cortical plate (CP) and ventricular zone. Patched was strongly upregulated in the ventricular zone and Gli1 in the CP. ...
Note:
Systemvoraussetzungen: PDF-Reader
In:
BioMed research international, New York [u.a.] : Hindawi, 2013-, (2015), Artikel-ID: 494269, 2314-6141
In:
year:2015
In:
elocationid:494269
Language:
English
URN:
urn:nbn:de:hebis:30:3-393893
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