UID:
almafu_9959327635502883
Umfang:
1 online resource (400 pages)
ISBN:
9783527630332
,
3527630333
,
9783527325856
,
3527325859
,
9783527630349
,
3527630341
,
1282687786
,
9781282687783
Inhalt:
A collection of highly valuable statistical and computational approaches designed for developing powerful methods to analyze large-scale high-throughput data derived from studies of complex diseases. Such diseases include cancer and cardiovascular disease, and constitute the major health challenges in industrialized countries. They are characterized by the systems properties of gene networks and their interrelations, instead of individual genes, whose malfunctioning manifests in pathological phenotypes, thus making the analysis of the resulting large data sets particularly challenging. This is.
Anmerkung:
Front Matter -- General Biological and Statistical Basics. The Biology of in Health and Disease: A High Altitude View / Brian C Turner, Gregory A Bird, Yosef Refaeli -- Cancer Stem Cells : Finding and Capping the Roots of Cancer / Eike C Buss, Anthony D Ho -- Multiple Testing Methods / Alessio Farcomeni -- Statistical and Computational Analysis Methods. Making Mountains out of Molehills: Moving from Single Gene to Pathway Based Models of Colon Cancer Progression / Elena Edelman, Katherine Garman, Anil Potti, Sayan Mukherjee -- Gene-Set Expression Analysis: Challenges and Tools / Assaf P Oron -- Multivariate Analysis of Microarray Data Using Hotelling's Test / Yan Lu, Peng-Yuan Liu, Hong-Wen Deng -- Interpreting Differential Coexpression of Gene Sets / Ju Han Kim, Sung Bum Cho, Jihun Kim -- Multivariate Analysis of Microarray Data: Application of MANOVA / Taeyoung Hwang, Taesung Park -- Testing Significance of a Class of Genes / James J Chen, Chen-An Tsai -- Differential Dependency Network Analysis to Identify Topological Changes in Biological Networks / Bai Zhang, Huai Li, Robert Clarke, Leena Hilakivi-Clarke, Yue Wang -- An Introduction to Time-Varying Connectivity Estimation for Gene Regulatory Networks / Andř Fujita, Joo Ricardo Sato, Marcos Angelo Almeida Demasi, Satoru Miyano, Mari Cleide Sogayar, Carlos Eduardo Ferreira -- A Systems Biology Approach to Construct a Cancer-Perturbed Protein-Protein Interaction Network for Apoptosis by Means of Microarray and Database Mining / Liang-Hui Chu, Bor-Sen Chen -- A New Gene Expression Meta-Analysis Technique and its Application to Co-Analyze Three Independent Lung Cancer Datasets / Irit Fishel, Alon Kaufman, Eytan Ruppin -- Kernel Classification Methods for Cancer Microarray Data / Tsuyoshi Kato, Wataru Fujibuchi -- Predicting Cancer Survival Using Expression Patterns / Anupama Reddy, Louis-Philippe Kronek, A Rose Brannon, Michael Seiler, Shridar Ganesan, W Kimryn Rathmell, Gyan Bhanot -- Integration of Microarray Datasets / Ki-Yeol Kim, Sun Young Rha -- Model Averaging for Biological Networks with Prior Information / Sach Mukherjee, Terence P Speed, Steven M Hill.
Weitere Ausg.:
Print version: Medical biostatistics for complex diseases. Weinheim : Wiley-VCH ; Chichester : John Wiley [distributor], 2010 ISBN 9783527325856
Weitere Ausg.:
ISBN 3527325859
Sprache:
Englisch
Schlagwort(e):
Electronic books.
;
Electronic books.
;
Electronic books.
DOI:
10.1002/9783527630332
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527630332
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527630332
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527630332
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