UID:
almahu_9948595853102882
Format:
1 online resource (2190 p.)
Edition:
3rd ed. / editor-in-chief, David Feldman ; associate editors, J. Wesley Pike, John S. Adams.
ISBN:
1-283-11471-2
,
9786613114716
,
0-12-381979-2
Content:
Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This 3e includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must-have resource for anyone working in endocrinology, osteology, bone biology, or cancer research.*Most comprehensive, up-to-date two-volume set o
Note:
Description based upon print version of record.
,
e9780123819789v1.pdf; Front Cover; Preface to the 3rd Edition; Chapter 92 -Control of Adaptive Immunity by Vitamin D Receptor Agonists; Chapter 95 -Vitamin D and Multiple Sclerosis; Preface to the 2nd Edition; Chapter 45 -Extrarenal 1α-Hydroxylase; Chapter 87 -The Vitamin D System and Colorectal Cancer Prevention; Introduction; Discovery of the Physiological Functions of Vitamin D; Renal Tubular Defects and Hypophosphatemia; Conclusion; Hepatic Diseases; Studies of Sun Exposure; Discovery of the Hormonal Form of Vitamin D; Histological Diagnosis of Osteomalacia; Biochemical Abnormalities
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AcknowledgmentsReferences; Chapter 2 - Photobiology of Vitamin D; Historical Perspective; Chapter 4 - CYP24A1: Structure, Function, and Physiological Role; Chapter 22 - Vitamin D Regulation of Type I Collagen Expression in Bone; Chapter 83 -Vitamin D: Cancer and Differentiation; Chapter 97 -Psoriasis and Other Skin Diseases; Section XII -Therapeutic Applications and New Advances; Sunlight, Vitamin D, and Skin Cancer; Vitamin D and Other Predictors of Calcium Retention; Vitamin D Intoxication And Cardiovascular Calcification: Pharmacological Considerations; Acknowledgment; References
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Vitamin DChapter 3 - The Activating Enzymes of Vitamin D Metabolism (25- and 1α-Hydroxylases); General Information Regarding Vitamin D Hydroxylases; Chapter 5 - The Vitamin D Binding Protein DBP; Chapter 23 - Target Genes: Bone Proteins; Procreative Relevance - Animal Models; Vitamin D Metabolism and Mechanism of Action; Chapter 56 -Genetics of the Vitamin D Endocrine System; The Clinical Features of HVDRR; Section IX -Analogs; Overview of Hematopoiesis; Immune Activity of 1,25-Dihydroxyvitamin D; Chapter 98 -The Role of Vitamin D in Type 2 Diabetes and Hypertension
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CYP24A1-Catalyzed PathwaysVitamin D Modulates Fracture Risk in Two Ways: By Increasing Bone Density and Decreasing Falls; CYP24A1: Properties, Function and Expression; Structure-Function Relationships; New World Primates; 1,25-Dihydroxyvitamin D3 Actions on Voltage-Sensitive Ca2+ Channels; Pancreatic Diseases; Perspectives; References; Vitamin D Binding Protein: Protein and Gene Structure; Properties of Mature Osteoblasts and Osteocytes; Conclusions and Perspectives; Cell-Type Specificity of Inhibition of Cell Proliferation by Vitamin D and Analogs Without Evidence of Differentiation
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Economic AspectsClosing Remarks; Future Research on Vitamin D and Respiratory/Allergic Disorders; Storage and Shipping; Vitamin D Biology; Localization and Proposed Functional Significance of the Calbindins; Idiopathic Hypercalciuria; VDR Research: The Biochemical Era; Assessment of Mineralization; Physiological and Pharmacological Actions of Vitamin D Analogs in Normal and Psoriatic Skin; VDR Research: The Molecular Biological Era; Concluding Comments; Vitamin D Amelioration of Established EAE; Acknowledgment
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Chapter 8 - Nuclear Vitamin D Receptor: Natural Ligands, Molecular Structure-Function, and Transcriptional Control of Vital ...
,
English
Additional Edition:
ISBN 0-12-381978-4
Language:
English
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