UID:
almahu_9949598802502882
Format:
1 online resource (xvi, 242 pages)
Edition:
First edition.
ISBN:
9781003386698
,
1003386695
,
9781000928648
,
1000928640
,
9781000928662
,
1000928667
Content:
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the obesity and metabolic syndrome epidemics, which this up-to-date book deals with comprehensively. The contents outline disease mechanisms, diagnostic tests, management, varying manifestations, and special populations. It covers the mechanistic pathways that contribute to NAFLD development, including the role of genetic variants and the gut microbiome. It elaborates on noninvasive diagnostic tests to screen for NAFLD, determine its severity, and monitor response to lifestyle intervention and pharmacologic treatment. This book helps clinicians diagnose and treat this common and potentially deadly disease. Key Features: Reviews current drugs in development and provides practical advice to clinicians on the diagnosis and management of fatty liver. Proves attractive to primary care providers who are on the front line of managing patients with NAFLD, to gastroenterologists and hepatologists who would benefit from updated data on how to risk-stratify patients and identify those who will be eligible for pharmacologic treatment, and other specialists such as cardiologists, endocrinologists, and nephrologists who will find this book to be a useful reference on the extrahepatic manifestations of NAFLD. Focuses on extrahepatic manifestations and new insights on the mechanistic drivers of the disease.
Note:
Includes index.
,
Preface - Naim Alkhouri and Stephen A HarrisonSection 1. Mechanisms of NAFLD Development1.Historical Perspectives and Clinical Presentation - Imad Asaad, Naim Alkouri2.Epidemiology and Natural History of Non-Alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis - Linda Henry, Zobair M Younossi3.Genetics of NAFLD - Luca Valenti, Cristiana Bianco4.Mechanisms of hepatocyte injury and inflammation in NAFLD - Gopanandan Parthasarathy, Harmeet Malhi5.The role of the microbiome - Carlos J Pirola and Silvia SookoianSection 2. Diagnostic Tests6.Simple Algorithms in Primary Care - Xixi Xu, and Michelle T. Long7.Ultrasound based techniques in NAFLD - Vikas Taneja, Nezam H Afdhal, and Michelle J Lai8.MRI-based technologies - Victor de Lédinghen9.Artificial intelligence in NAFLD diagnosis - Joseph C. Ahn, and Samer GawriehSection 3. Management10.Dietary interventions - Monica Tincopa11.Weight Loss Medications - Mohammad Qasim Khan, Manhal Izzy, Kymberly D. Watt12.De novo lipogenesis inhibitors - Brent A. Neuschwander-Tetri13.Targeting bile acids (FXRs and FGF19) - Daniel Garrido, Rukaiya Bashir Hamidu, Dina Halegoua-DeMarzio14.PPAR agonists - Sven MA Francque15.Anti-inflammatory drugs: Metabolic inflammation in NASH as a therapeutic target - Angelo Armandi, Jörn M. Schattenberg16.Practical Aspects of Pharmacologic Management - Naim Alkhouri and Stephen A. HarrisonSection 4. Extrahepatic Manifestations17.Endocrinology: Diabetes and other endocrinopathies - Scott Isaacs, Julio Leey18.Obstructive Sleep Apnea and Non-Alcoholic Fatty Liver Disease - Dania Brigham and Shikha S. Sundaram19.Extrahepatic Gastrointestinal Manifestations of Non-alcoholic Fatty Liver Disease - Rinjal Brahmbhatt, Mousab Tabbaa20.Extrahepatic and Hepatic cancers - Maryam Ibrahim, Tracey G. SimonSection 5. NAFLD in special populations21.NAFLD in Children: Unique Aspects and Controversies - Samar H Ibrahim, Rohit Kohli22.NAFLD in HIV patients - Giada Sebastiani23.NAFLD in Liver Transplant Recipients - Liyun Yuan and Norah Terrault24.NAFLD in lean individuals - Donghee Kim and Vincent Wai-Sun Wong
Language:
English
DOI:
10.1201/9781003386698
URL:
https://www.taylorfrancis.com/books/9781003386698
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