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  • 1
    Book
    Book
    Neurotransmitter transporters / (1998)
    San Diego [u.a.] :Acad. Press,
    Details
    UID:
    almafu_BV012223353
    Format: XXXIV, 784 S. : Ill., graph. Darst.
    ISBN: 0-12-182197-8
    Series Statement: Methods in enzymology 296
    Language: English
    Subjects: Biology
    RVK:
    WC 4355
    RVK:
    WD 5050
    Keywords: Neurotransmitter ; Carrier-Proteine ; Methode ; Neurotransmitter ; Carrier-Proteine ; Biochemische Methode ; Neurotransmitter ; Carrier-Proteine ; Aufsatzsammlung
    URL: Inhaltsverzeichnis
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  • 2
    Online Resource
    Online Resource
    Reviews of Physiology, Biochemistry and Pharmacology 161 (2011)
    Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg
    Details
    UID:
    gbv_165128704X
    Format: Online-Ressource (V, 110p. 13 illus., 10 illus. in color, digital)
    ISBN: 9783540876311 , 1283369532 , 9781283369534
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology 161
    Content: This title includes: F. Schweda and A. Kurtz: ""Regulation of Renin Release by Local and Systemic Factors""; M. Krauss and V. Haucke: ""Shaping Membranes for Endocytosis; B.M. Jockusch and P.L. Graumann: ""The Long Journey: Actin on the Road to Pro- and Eukaryotic Cells""; B. Colsoul, R. Vennekens and B. Nilius: ""Transient Receptor Potential (TRP) Cation Channels in Pancreatic ss cells
    Content: 1 Basic Mechanisms of Insulin Secretion in Beta Cells2 Role of Ion Channels: The Classical View; 3 Expression of TRP Channels in Pancreatic b Cells; 4 Modulation of Insulin Release by TRP Channels; 4.1 TRP Canonicals; 4.2 TRPM2; 4.3 TRPM3; 4.4 TRPM4; 5 TRPM5 as a Modulator of Ca 2+ Oscillations; 6 Lessons Form Knock-Out Models: TRPM2 and TRPM5; 7 An Intestinal TRPM5 Connection: Incretins; 8 TRPM3: A Zinc Connection; 9 TRP Channels and a Possible Role in Diabetes Type II; 10 TRPM5 as a Drug Target; 11 A Critical View: From Mouse to Man; References
    Content: A Matter of Stretching and Squeezing: Mechanical Forces Sculpt the MembraneOutlook; References; The Long Journey: Actin on the Road to Pro- and Eukaryotic Cells; 1 Actin Homologues Are Present in Pro- and Eukaryotes; 2 Actin Filament-Based Dynamics in Eukaryotic and Prokaryotic Cells; 3 Involvement of Eukaryotic Actins in Nuclear Functions; 4 Comparing Pro- and Eukaryotic Actins: Dissimilarities and Similarities; 5 Evolution of the Eukaryotic Cell; 6 The Pathway of the Actin Ancestor; 7 Conclusion; References; Transient Receptor Potential Cation Channels in Pancreatic b Cells
    Content: Blood pressureRegulation of renin release by salt load; References; Shaping Membranes for Endocytosis; Taking a Trip into the Cell; Clathrin-Mediated Endocytosis; Caveolae-Mediated Endocytosis; Clathrin- and Caveolin-Independent Endocytosis; Phagocytosis; Generating Membrane Curvature at the Plasma Membrane; Asymmetric Membrane Expansion: Dipping Fingers into the Sea; Stabilizing Curved Membrane Domains by Biological Basket Weaving; Curving Through BARs; Assisting Curvature Induction: Local Changes in Lipid Composition and Organization
    Content: Reviews of Physiology, Biochemistryand Pharmacology; Contents; Regulation of Renin Release by Local and Systemic Factors; Introduction; The Process of Renin secretion; Intracellular signaling pathways controlling renin release; Cyclic AMP; Cyclic GMP; Calcium; Electrophysiology of JG cells; Role of intercellular communication for renin secretion; Locally acting factors that regulate renin release; Atrial natriuretic peptide; Angiotensin II; Prostaglandins E 2 and I 2; Nitric oxide; The macula densa mechanism; Renal baroreceptor mechanism; Systemic factors controlling renin release
    Note: Includes bibliographical references
    Additional Edition: ISBN 9783540876281
    Additional Edition: Buchausg. u.d.T. ISBN 978-3-540-87628-1
    Language: English
    DOI: 10.1007/978-3-540-87631-1
    URL: Volltext
    URL: Volltext  (lizenzpflichtig)
    Author information: Offermanns, Stefan 1964-
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  • 3
    Online Resource
    Online Resource
    Reviews of Physiology, Biochemistry and Pharmacology (2007)
    Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg
    Details
    UID:
    gbv_1647127955
    Format: Online-Ressource (IV, 160 p. 14 illus, digital)
    ISBN: 9783540717911
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology 158
    Content: Igor Smurov
    Content: Contents E.I. Christensen and R. Nielsen: Role of Megalin and Cubilin in Renal Physiology and Pathophysiology G. Zifarelli and M. Pusch: CLC Chloride Channels and Transporters: A Biophysical and Physiological Perspective S.F.J. van de Graaf, R.J.M. Bindels and J.G.J. Hoenderop: Physiology of Epithelial Ca2 and Mg2+ Transport
    Note: Description based upon print version of record , Role of megalin and cubilin in renal physiology and pathophysiology; CLC chloride channels and transporters: a biophysical and physiological perspective; Physiology of epithelial Ca2+ and Mg2+ transport;
    Additional Edition: ISBN 9783540717904
    Additional Edition: Buchausg. u.d.T. Reviews of physiology, biochemistry and pharmacology ; 158 2007 ISBN 9783540717904
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
    RVK:
    VT 5000
    RVK:
    WW 1584
    DOI: 10.1007/978-3-540-71791-1
    URL: Volltext
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 4
    Online Resource
    Online Resource
    Reviews of Physiology, Biochemistry and Pharmacology (2007)
    Berlin, Heidelberg : Springer Berlin Heidelberg
    Details
    UID:
    gbv_1647381932
    Format: Online-Ressource (digital)
    ISBN: 9783540738008
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology 159
    Additional Edition: ISBN 9783540737995
    Additional Edition: Buchausg. u.d.T. ISBN 978-3-540-73799-5
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
    RVK:
    VT 5000
    RVK:
    WW 1584
    DOI: 10.1007/978-3-540-73800-8
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 5
    Online Resource
    Online Resource
    Reviews of Physiology, Biochemistry and Pharmacology, Vol. 164 (2013)
    Cham : Springer International Publishing
    Details
    UID:
    gbv_1653018275
    Format: Online-Ressource (V, 116 p. 16 illus., 14 illus. in color, online resource)
    ISBN: 9783319009964
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology 164
    Content: T. Hara, I. Kimura, D. Inoue, A. Ichimura, and A. Hirasawa: Free fatty acid receptors and their role in regulation of energy metabolism. B. Nilius and G. Appendino. Spices: the savory and healthy science of pungency
    Note: Description based upon print version of record , Contents; Spices: The Savory and Beneficial Science of Pungency; 1 Introduction; 2 A Historical Cultural Sojourn: The Role of Spices in History; 3 The Taste Machinery; 4 The Alien Taste Receptors; 5 The Chemesthetic System; 6 Spicy Plants; 6.1 The Case of TRPV1; 6.2 ``Irritant´´ Pungency: TRPA1 A New Player; 6.3 A Gustatory and Beneficial TRPM5 Connection; 7 Spices, TRPs and Health; 7.1 Spices and Obesity; 7.2 A Skeletal Muscle Connection; 7.3 Spices Against Pain; 7.4 Spices Against Cancer; 7.5 A Cytoprotective and Anti-inflammatory Action of Spices; 7.6 Antimicrobic Action of Spices , 7.7 Spices in Gastro-intestinal Diseases7.8 Do Spices Go Cardio-vascular?; 7.9 TRPA1 and Cough; 7.10 A Spicy Pancreas Connection?; 7.11 An Action of Spicy Channel Activators in the Brain?; 7.12 A Bone Connection?; 7.12.1 Bioavailability: The Gray Side of Spices; 7.12.2 Spices as Double-Edged Swords: Do They Have a Toxic Dark Side?; 8 Concluding Remarks; References; Free Fatty Acid Receptors and Their Role in Regulation of Energy Metabolism; 1 Introduction; 2 FFA2 (GPR43); 2.1 Ligands; 2.2 Selective Compound; 2.3 Signal Transduction; 2.4 Expression and Physiological Functions , 2.4.1 Adipose Tissues2.4.2 Adipogenesis; 2.4.3 Lipolysis; 2.4.4 Leptin Secretion; 2.4.5 Intestine; 2.4.6 PYY Secretion; 2.4.7 GLP-1 Secretion; 2.4.8 Intestinal Motility; 3 FFA3 (GPR41); 3.1 Ligands; 3.2 Signal Transduction; 3.3 Expression and Physiological Functions; 3.3.1 Adipose Tissue; 3.3.2 Intestine; 3.3.3 Sympathetic Nervous System (SNS); 4 FFA1 (GPR40); 4.1 Ligands; 4.2 Selective Ligands; 4.3 Signal Transduction; 4.4 Expression and Physiological Functions; 4.4.1 Pancreas; 4.4.2 Intestine; 4.4.3 Taste Buds; 4.4.4 Brain; 4.4.5 Mammary Gland; 4.5 Polymorphism , 4.6 Structure-Activity Relationships (SARs)4.7 Binding Assay; 4.8 Clinical Trials; 5 GPR84; 5.1 Ligands; 5.2 Signal Transduction; 5.3 Expression and Physiological Functions; 5.3.1 Immune System; 5.3.2 Adipose Tissue; 6 GPR120; 6.1 Ligands; 6.2 Signal Transduction; 6.3 Expression and Physiological Functions; 6.3.1 Intestine; 6.3.2 Macrophages; 6.3.3 Adipocytes; 6.3.4 Taste Buds; 6.3.5 Lung; 6.4 Genetic Contribution to Type 2 Diabetes; 6.5 The Future; References
    Additional Edition: ISBN 9783319009957
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-331-90099-5-7
    Language: English
    DOI: 10.1007/978-3-319-00996-4
    URL: Volltext
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Author information: Offermanns, Stefan 1964-
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  • 6
    Online Resource
    Online Resource
    Reviews of Physiology, Biochemistry and Pharmacology : Volume 162 (2012)
    Berlin, Heidelberg : Springer Berlin Heidelberg
    Details
    UID:
    gbv_1651500150
    Format: Online-Ressource (V, 119 p. 20 illus., 16 illus. in color, digital)
    ISBN: 9783642292569 , 128362706X , 9781283627061
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology 162
    Content: Cardiac ion channels and mechanisms for protection against atrial fibrillation. Intrinsically photosensitive retinal ganglion cells. Quantifying and modeling the temperature-dependent gating of TRP channels.
    Content: Cardiac ion channels and mechanisms for protection against atrial fibrillation. Intrinsically photosensitive retinal ganglion cells. Quantifying and modeling the temperature-dependent gating of TRP channels
    Note: Description based upon print version of record , Reviews of Physiology, Biochemistry and Pharmacology 162; Contents; Cardiac Ion Channels and Mechanisms for Protection Against Atrial Fibrillation; Introduction; Mechanisms and Aetiology of Arrhythmias; Triggers of Arrhythmias; Substrates of Arrhythmias; Atrial Fibrillation; Ion Channel Composition in Atria and Ventricles; Phase 0; Phase 1; Phase 2; Phase 3; Phase 4; Remodeling; Remodeling of Atria-Selective Currents; Cardiac Calcium Activated K+ Channels; Literature on SK Channels in the Atria; Discussion of Data on the Effects of Apamin in Atrial SK Channels; Management of AF , IKACh BlockersNTC-801; NIP-151 and NIP-142; IKur Blockers; AVE0118; DPO-1; S9947; KVI-020/WYE-160020; XEN-D0101 and XEN-D0103; Atria-Selective Sodium Channel Block; Ranolazine; Multichannel Blockers; Amiodarone; K201 (JVT-519); Tedisamil; AZD1305; Derivatives of Existing Drugs; Dronedarone; Budiodarone (ATI-2042); Celivarone; Novel Drugs Approved for the Treatment of AF; Vernakalant; Conclusion; References; Intrinsically Photosensitive Retinal Ganglion Cells; Early Hints of a Third Photoreceptor in the Mammalian Retina; The Convergence of Retinal Physiology and Internal Time Keeping , Melanopsin, the Photopigment of Intrinsically Photosensitive Retinal Ganglion CellsSCN-Projecting RGCs Are Intrinsically Photosensitive and Express Melanopsin; Melanopsin Is a Photopigment; ipRGC Physiological Responses to Light; ipRGC Response Kinetics; Photon Capture in ipRGCs Results in Membrane Depolarization; Chromophore Recycling and Bistability; Multiple ipRGC Subtypes with Widespread Axonal Projections; ipRGCs Targets in the Brain; ipRGC Intraretinal Signaling; ipRGCs Provide Excitatory Drive to Dopaminergic Amacrine Cells , ipRGCs Are Coupled to GABAergic Amacrine Cells via Gap JunctionsDifferent Types of ipRGC Have Different Central Targets; ipRGC Input to the Ventrolateral Preoptic Nucleus; ipRGC Input to the SCN and Seasonal Affective Disorder; ipRGCs and Retinal Disease; The Future; References; Quantifying and Modeling the Temperature-Dependent Gating of TRP Channels; 1 Introduction; 1.1 Thermosensation in Mammals; 1.2 A Definition of ThermoTRPs; 2 Parametrizing ThermoTRPs: Q10 and Thermal Threshold?; 3 Basic Characteristic of Prototype ThermoTRPs: TRPM8 and TRPV1; 4 Models of Thermosensitive Gating , 4.1 Linear Models4.1.1 The Two-State Model; 4.1.2 Multistate Linear Models; 4.2 Allosteric Models; 4.2.1 The Monod-Wyman-Changeux-Type Allosteric Model; 4.2.2 The Dual-Allosteric Coupling Model; 5 What Is the Best Model?; 6 What Can We Learn from Structure-Function Studies (and What Not)?; 7 Conclusions and Outlook; References;
    Additional Edition: ISBN 9783642292552
    Additional Edition: Buchausg. u.d.T. ISBN 978-3-642-29255-2
    Language: English
    Subjects: Chemistry/Pharmacy
    RVK:
    VT 5000
    Keywords: Physiologie ; Biochemie ; Pharmakologie
    DOI: 10.1007/978-3-642-29256-9
    URL: Volltext
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Author information: Offermanns, Stefan 1964-
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  • 7
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    Online Resource
    Reviews of Physiology, Biochemistry and Pharmacology, Vol. 163 (2012)
    Berlin : Springer
    Details
    UID:
    gbv_1651969140
    Format: Online-Ressource (V, 131 p. 9 illus., 5 illus. in color, digital)
    ISBN: 9783642335211
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology 163
    Content: D. Sinnecker, R. J. Dirschinger, A. Goedel, A. Moretti, P. Lipp, K.-L. LaugwitzInduced Pluripotent Stem Cells in Cardiovascular ResearchR. Vennekens, A. Menigoz, B. NiliusTRPs in the brainA. Oláh, A. Gábor Szöllösi, T. BíróThe Channel Physiology of the Skin
    Note: Description based upon print version of record , Induced pluripotent stem cells in cardiovascular research -- TRPs in the brain -- Chemosensory receptors and channels in the respiratory tract: role in toxic lung injury and potential  as "sweet spots" for targeted therapies.​- The channel physiology of the skin.
    Additional Edition: ISBN 9783642335204
    Additional Edition: Buchausg. u.d.T. ISBN 978-3-642-33520-4
    Language: English
    DOI: 10.1007/978-3-642-33521-1
    URL: Volltext
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Author information: Offermanns, Stefan 1964-
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  • 8
    Online Resource
    Online Resource
    Reviews of Physiology, Biochemistry and Pharmacology, Vol. 165 (2013)
    Cham : Springer International Publishing
    Details
    UID:
    gbv_1653044233
    Format: Online-Ressource (V, 96 p. 12 illus., 9 illus. in color, online resource)
    ISBN: 9783319009995
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology 165
    Content: T. Büch, E. Schäfer, D. Steinritz, A. Dietrich, T. Gudermann: Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as 'Sweet Spots' for Targeted Therapies. D.C. Zebrowski and F. B. Engel: The Cardiomyocyte Cell Cycle in Hypertrophy, Tissue Homeostasis, and Regeneration. P. Hegyi and O.H. Petersen: The Exocrine Pancreas: The Acinar -Ductal Tango in Physiology and Pathophysiology.
    Content: T. Büch, E. Schäfer, D. Steinritz, A. Dietrich, T. Gudermann: Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as "Sweet Spots" for Targeted Therapies. D.C. Zebrowski and F. B. Engel: The Cardiomyocyte Cell Cycle in Hypertrophy, Tissue Homeostasis, and Regeneration. P. Hegyi and O.H. Petersen: The Exocrine Pancreas: The Acinar -Ductal Tango in Physiology and Pathophysiology.
    Note: Description based upon print version of record , T. Büch, E. Schäfer, D. Steinritz, A. Dietrich, T. Gudermann: Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as "Sweet Spots" for Targeted TherapiesD.C. Zebrowski and F. B. Engel: The Cardiomyocyte Cell Cycle in Hypertrophy, Tissue Homeostasis, and Regeneration -- P. Hegyi and O.H. Petersen: The Exocrine Pancreas: The Acinar -Ductal Tango in Physiology and Pathophysiology. .
    Additional Edition: ISBN 9783319009988
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-331-90099-8-8
    Language: English
    DOI: 10.1007/978-3-319-00999-5
    URL: Volltext
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Author information: Offermanns, Stefan 1964-
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