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  • 1
    UID:
    almafu_BV017109796
    Format: XIV, 246 S.
    ISBN: 0-471-27398-8
    Series Statement: Wiley series in probability and statistics
    Note: Includes bibliographical references and index
    Language: English
    Subjects: Biology
    RVK:
    RVK:
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  • 2
    UID:
    almafu_9959328266602883
    Format: 1 online resource
    Edition: Second edition.
    ISBN: 9781118364529 , 111836452X , 9781118364536 , 1118364538 , 9781118364543 , 1118364546 , 9781118364505 , 1118364503
    Content: Praise for the First Edition " ... extremely well written ... a comprehensive and up-to-date overview of this important field."--Journal of Environmental Quality Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition provides comprehensive coverage of recent advancements in microarray data analysis. A cutting-edge guide, the Second Edition demonstrates various methodologies for analyzing data in biomedical research and offers an overview of the modern techniques used in microarray technology to.
    Note: Cover; Title Page; Contents; Preface; Chapter 1 A Brief Introduction; 1.1 A Note on Exploratory Data Analysis; 1.2 Computing Considerations and Software; 1.3 A Brief Outline of the Book; 1.4 Data Sets and Case Studies; 1.4.1 The Golub Data; 1.4.2 The Mouse5 Data; 1.4.3 The Khan Data; 1.4.4 The Sialin Data; 1.4.5 The Behavioral Study Data; 1.4.6 The Spiked-In Data; 1.4.7 The APOAI Study; 1.4.8 The Breast Cancer Data; 1.4.9 Platinum Spike Data Set; 1.4.10 Human Epidermal Squamous Carcinoma Cell Line A431 Experiment; 1.4.11 Note: Public Repositories of Microarray Data; Chapter 2 Genomics Basics. , 2.1 Genes2.2 Deoxyribonucleic Acid; 2.3 Gene Expression; 2.4 Hybridization Assays and Other Laboratory Techniques; 2.5 The Human Genome; 2.6 Genome Variations and Their Consequences; 2.7 Genomics; 2.8 The Role of Genomics in Pharmaceutical Research and Clinical Practice; 2.9 Proteins; 2.10 Bioinformatics; Supplementary Reading; Chapter 3 Microarrays; 3.1 Types of Microarray Experiments; 3.1.1 Experiment Type 1: Tissue-Specific Gene Expression; 3.1.2 Experiment Type 2: Developmental Genetics; 3.1.3 Experiment Type 3: Genetic Diseases; 3.1.4 Experiment Type 4: Complex Diseases. , 3.1.5 Experiment Type 5: Pharmacological Agents3.1.6 Experiment Type 6: Plant Breeding; 3.1.7 Experiment Type 7: Environmental Monitoring; 3.2 A Very Simple Hypothetical Microarray Experiment; 3.3 A Typical Microarray Experiment; 3.3.1 Microarray Preparation; 3.3.2 Sample Preparation; 3.3.3 The Hybridization Step; 3.3.4 Scanning the Microarray; 3.3.5 Interpreting the Scanned Image; 3.4 Multichannel cDNA Microarrays; 3.5 Oligonucleotide Microarrays; 3.6 Bead-Based Arrays; 3.7 Confirmation of Microarray Results; Supplementary Reading and Electronic References. , Chapter 4 Processing the Scanned Image4.1 Converting the Scanned Image to the Spotted Image; 4.1.1 Gridding; 4.1.2 Segmentation; 4.1.3 Quantification; 4.2 Quality Assessment; 4.2.1 Visualizing the Spotted Image; 4.2.2 Numerical Evaluation of Array Quality; 4.2.3 Spatial Problems; 4.2.4 Spatial Randomness; 4.2.5 Quality Control of Arrays; 4.2.6 Assessment of Spot Quality; 4.3 Adjusting for Background; 4.3.1 Estimating the Background; 4.3.2 Adjusting for the Estimated Background; 4.4 Expression-Level Calculation for Two-Channel cDNA Microarrays. , 4.5 Expression-Level Calculation for Oligonucleotide Microarrays4.5.1 The Average Difference; 4.5.2 A Weighted Average Difference; 4.5.3 Perfect Matches Only; 4.5.4 Background Adjustment Approach; 4.5.5 Model-Based Approach; 4.5.6 Absent-Present Calls; Supplementary Reading; Software Notes; Chapter 5 Preprocessing Microarray Data; 5.1 Logarithmic Transformation; 5.2 Variance Stabilizing Transformations; 5.3 Sources of Bias; 5.4 Normalization; 5.5 Intensity-Dependent Normalization; 5.5.1 Smooth Function Normalization; 5.5.2 Quantile Normalization; 5.5.3 Stagewise Normalization.
    Additional Edition: Print version: Amaratunga, Dhammika, 1956- Exploration and analysis of DNA microarray and other high dimensional data. Hoboken, New Jersey : John Wiley & Sons, Inc., [2013] ISBN 9781118356333
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books.
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  • 3
    UID:
    edocfu_9959327459502883
    Format: 1 online resource (xiv, 246 pages) : , illustrations
    ISBN: 9780470317129 , 0470317124 , 9780470317969 , 0470317965 , 9780471273981 , 0471273988
    Content: A cutting-edge guide to the analysis of DNA microarray data. Genomics is one of the major scientific revolutions of this century, and the use of microarrays to rapidly analyze numerous DNA samples has enabled scientists to make sense of mountains of genomic data through statistical analysis. Today, microarrays are being used in biomedical research to study such vital areas as a drug's therapeutic value-or toxicity-and cancer-spreading patterns of gene activity. Exploration and Analysis of DNA Microarray and Protein Array Data answers the need for a comprehensive, cutting-edge overview of this.
    Note: Exploration and Analysis of DNA Microarray and Protein A rray Data; Contents; Preface; 1. A Brief Introduction; 2. Genomics Basics; 3. Microarrays; 4. Processing the Scanned Image; 5. Preprocessing Microarray Data; 6. Summarization; 7. Two-Group Comparative Experiments; 8. Model-Based Inference and Experimental Design Considerations; 9. Pattern Discovery; 10. Class Prediction; 11. Protein Arrays; References; Author Index; Subject Index. , English.
    Additional Edition: Print version: Amaratunga, Dhammika, 1956- Exploration and analysis of DNA microarray and protein array data. Hoboken, NJ : John Wiley, ©2004 ISBN 0471273988
    Additional Edition: ISBN 9780471273981
    Language: English
    Keywords: Electronic books.
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    UID:
    almahu_9948197190202882
    Format: 1 online resource (xiv, 246 pages) : , illustrations
    ISBN: 9780470317129 , 0470317124 , 9780470317969 , 0470317965 , 9780471273981 , 0471273988
    Content: A cutting-edge guide to the analysis of DNA microarray data. Genomics is one of the major scientific revolutions of this century, and the use of microarrays to rapidly analyze numerous DNA samples has enabled scientists to make sense of mountains of genomic data through statistical analysis. Today, microarrays are being used in biomedical research to study such vital areas as a drug's therapeutic value-or toxicity-and cancer-spreading patterns of gene activity. Exploration and Analysis of DNA Microarray and Protein Array Data answers the need for a comprehensive, cutting-edge overview of this.
    Note: Exploration and Analysis of DNA Microarray and Protein A rray Data; Contents; Preface; 1. A Brief Introduction; 2. Genomics Basics; 3. Microarrays; 4. Processing the Scanned Image; 5. Preprocessing Microarray Data; 6. Summarization; 7. Two-Group Comparative Experiments; 8. Model-Based Inference and Experimental Design Considerations; 9. Pattern Discovery; 10. Class Prediction; 11. Protein Arrays; References; Author Index; Subject Index. , English.
    Additional Edition: Print version: Amaratunga, Dhammika, 1956- Exploration and analysis of DNA microarray and protein array data. Hoboken, NJ : John Wiley, ©2004 ISBN 0471273988
    Additional Edition: ISBN 9780471273981
    Language: English
    Keywords: Electronic books.
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    UID:
    almahu_9948319477102882
    Format: 1 online resource (346 pages) : , illustrations.
    Edition: Second edition.
    ISBN: 9781118364536 (e-book)
    Series Statement: Wiley series in probability and statistics
    Additional Edition: Print version: Amaratunga, Dhammika, 1956- Exploration and analysis of DNA microarray and other high dimensional data. Hoboken, New Jersey : John Wiley & Sons, c2014 ISBN 9781118356333
    Language: English
    Keywords: Electronic books.
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  • 6
    UID:
    almahu_BV041579038
    Format: XVI, 317 S. : , Ill., graph. Darst.
    Edition: 2. ed.
    ISBN: 978-1-11-835633-3
    Series Statement: Wiley series in probability and statistics
    Note: Includes bibliographical references and index
    Language: English
    Subjects: Biology
    RVK:
    Keywords: DNS-Chip ; Datenanalyse
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  • 7
    UID:
    edocfu_9958352736802883
    Format: 1 online resource (352 p.) : , 10 halftones 1 frontispiece
    Edition: Course Book
    ISBN: 9781400851607
    Series Statement: Princeton Legacy Library ; 401
    Content: This collection of essays brings together many of the world's most distinguished statisticians to discuss a wide array of the most important recent developments in data analysis. The book honors John W. Tukey, one of the most influential statisticians of the twentieth century, on the occasion of his eightieth birthday. Contributors, some of them Tukey's former students, use his general theoretical work and his specific contributions to Exploratory Data Analysis as the point of departure for their papers. They cover topics from "pure" data analysis, such as gaussianizing transformations and regression estimates, and from "applied" subjects, such as the best way to rank the abilities of chess players or to estimate the abundance of birds in a particular area.Tukey may be best known for coining the common computer term "bit," for binary digit, but his broader work has revolutionized the way statisticians think about and analyze sets of data. In a personal interview that opens the book, he reviews these extraordinary contributions and his life with characteristic modesty, humor, and intelligence. The book will be valuable both to researchers and students interested in current theoretical and practical data analysis and as a testament to Tukey's lasting influence.The essays are by Dhammika Amaratunga, David Andrews, David Brillinger, Christopher Field, Leo Goodman, Frank Hampel, John Hartigan, Peter Huber, Mia Hubert, Clifford Hurvich, Karen Kafadar, Colin Mallows, Stephan Morgenthaler, Frederick Mosteller, Ha Nguyen, Elvezio Ronchetti, Peter Rousseeuw, Allan Seheult, Paul Velleman, Maria-Pia Victoria-Feser, and Alessandro Villa.Originally published in 1998.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
    Note: Frontmatter -- , Contents -- , Preface -- , Opening Material -- , Introductory Remarks by the Editors -- , Biographical Information -- , Curriculum Vitae of John Wilder Tukey -- , Ph.D. Theses Directed by John W. Tukey Princeton University, 1940-1990 -- , Partial List of John W. Tukey's Grandstudents -- , A Conversation with John W. Tukey -- , Elizabeth Tukey's Speech -- , Program of the Conference in Honor of John W. Tukey on His 80th Birthday -- , List of Participants -- , Scientific Papers -- , Errors-in-Variables Regression Estimators That Have High Breakdown and High Gaussian Efficiency -- , The Analytic Jackknife -- , Assessing Connections in Networks of Biological Neurons -- , Estimating Abundances for a Breeding Bird Atlas -- , Statistical Methods, Graphical Displays, and Tukey's Ladder of Re-Expression in the Analysis of Nonindependence in Contingency Tables: Correspondence Analysis, Association Analysis, and the Midway View of Nonindependence -- , Some Additional Notes on the "Princeton Robustness Year" -- , Tracking Chess Players' Abilities -- , Speculations on the Path of Statistics -- , A Regression Analysis with Categorical Covariables, Two-way Heteroscedasticity, and Hidden Outliers -- , Mean Square over Degrees of Freedom: New Perspectives on a Model Selection Treasure -- , Geographical Trends in Cancer Mortality: Spatial Smoothers and Adjustment -- , Covering Designs in Random Environments -- , Gaussianizing Transformations and Estimation -- , The Tennessee Study of Class Size in the Early School Grades -- , On the Distribution of Order Statistics from a p-wild Distribution -- , Resistant Modeling of Income Distributions and Inequality Measures -- , Bonus Decompositions for Robust Analysis of 2™ Factorial Experiments -- , The Philosophical Past and the Digital Future of Data Analysis: 375 Years of Philosophical Guidance for Software Design on the Occasion of John W. Tukey's 80th Birthday -- , REFERENCES , In English.
    Language: English
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  • 8
    UID:
    almafu_9959327459502883
    Format: 1 online resource (xiv, 246 pages) : , illustrations
    ISBN: 9780470317129 , 0470317124 , 9780470317969 , 0470317965 , 9780471273981 , 0471273988
    Content: A cutting-edge guide to the analysis of DNA microarray data. Genomics is one of the major scientific revolutions of this century, and the use of microarrays to rapidly analyze numerous DNA samples has enabled scientists to make sense of mountains of genomic data through statistical analysis. Today, microarrays are being used in biomedical research to study such vital areas as a drug's therapeutic value-or toxicity-and cancer-spreading patterns of gene activity. Exploration and Analysis of DNA Microarray and Protein Array Data answers the need for a comprehensive, cutting-edge overview of this.
    Note: Exploration and Analysis of DNA Microarray and Protein A rray Data; Contents; Preface; 1. A Brief Introduction; 2. Genomics Basics; 3. Microarrays; 4. Processing the Scanned Image; 5. Preprocessing Microarray Data; 6. Summarization; 7. Two-Group Comparative Experiments; 8. Model-Based Inference and Experimental Design Considerations; 9. Pattern Discovery; 10. Class Prediction; 11. Protein Arrays; References; Author Index; Subject Index. , English.
    Additional Edition: Print version: Amaratunga, Dhammika, 1956- Exploration and analysis of DNA microarray and protein array data. Hoboken, NJ : John Wiley, ©2004 ISBN 0471273988
    Additional Edition: ISBN 9780471273981
    Language: English
    Keywords: Electronic books.
    Library Location Call Number Volume/Issue/Year Availability
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