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  • 1
    Online Resource
    Online Resource
    London, [England] ; : Academic Press,
    UID:
    almahu_9949697942302882
    Format: 1 online resource (1393 p.)
    Edition: Fifth edition.
    ISBN: 0-12-407738-2
    Uniform Title: Neurology and general medicine (Aminoff)
    Content: Aminoff's Neurology and General Medicine is the standard and classic reference providing comprehensive coverage of the relationship between neurological practice and general medicine. As neurologists are asked to consult on general medical conditions, this reference provides an authoritative tool linking general medical conditions to specific neurological issues and disorders. This is also a valuable tool for the general practitioner seeking to understand the neurological aspects of their medical practice. Completely revised with new chapters covering metastatic disease, bladder disease, psychogenic disorders, dementia, and pre-operative and post-operative care of patients with neurologic disorders, this new edition will again be the go-to reference for both neurologists and general practitioners.
    Note: Description based upon print version of record. , Front Cover -- Aminoff's Neurology and General Medicine -- Copyright Page -- Contributors -- Preface to the Fifth Edition -- Preface to the First Edition -- Contents -- I: Respiratory and Cardiovascular Disorders -- 1 Breathing and the Nervous System -- Control of Breathing -- Respiratory Muscles -- Chemical Control of Breathing -- Brainstem Respiratory Centers -- Voluntary Control of Breathing -- Integrated Neural Control of Breathing -- Evaluation of Pulmonary Function -- Clinical Assessment -- Tests of Respiratory Functions -- Arterial Blood Gas Studies -- Imaging -- Pulmonary Function Tests -- Polysomnography -- Patterns of Respiratory Dysfunction -- Disorders of Involuntary Breathing -- Disorders of Voluntary Breathing -- Central Neurogenic Hyperventilation -- Apraxia of Breathing -- Posthyperventilation Apnea -- Apneustic Breathing -- Cheyne-Stokes Breathing -- Ataxic Breathing -- Cluster Breathing -- Other Conditions -- Respiratory Dysfunction from Neurologic Disorders -- Central Nervous System -- Acute Respiratory Dysfunction -- Neurogenic Pulmonary Edema -- Trauma to Brain and Spinal Cord -- Acute Nontraumatic High Myelopathies -- Multiple Sclerosis -- Stroke -- Brain Tumors -- Chronic Respiratory Dysfunction -- Parkinson Disease -- Multiple System Atrophy -- Other Neurologic Disorders -- Peripheral Nervous System -- Anterior Horn Cell Disorders -- Amyotrophic Lateral Sclerosis -- Other Anterior Horn Cell Disorders -- Neuropathies -- Guillain-Barré Syndrome -- Phrenic Nerve Mononeuropathies -- Critical Illness Polyneuropathy -- Other Neuropathies -- Neuromuscular Junction Disorders -- Myopathies -- Muscular Dystrophies -- Critical Illness Myopathy -- Other Muscle Disorders -- Disorders of Breathing Associated with Sleep -- Upper Airway Obstruction -- Central Sleep Apnea Syndrome -- Sleep Hypoventilation Syndrome. , Respiratory Dysrhythmias -- Neurologic Effects of Respiratory Dysfunction -- Dysfunction Related to Pulmonary Pathology -- Hypoxia -- Hypercapnia -- Hypocapnia -- Dysfunction Related to Obstructive Sleep Apnea -- Vascular Disorders -- Headache -- Cognitive Dysfunction and Dementia -- References -- 2 Neurologic Complications of Aortic Disease and Surgery -- Clinical Neurologic Syndromes Due to Aortic Pathology -- Spinal Cord Ischemia -- Anatomy -- Embryologic Development -- Anterior Spinal Artery -- Posterior Spinal Arteries -- Intrinsic Blood Supply of the Spinal Cord -- Ischemic Cord Syndromes -- Anterior Spinal Artery Syndrome -- Motor Neuron Disease -- Posterior Spinal Artery Syndrome -- Unilateral Cord Syndromes -- Intermittent Claudication -- Cerebral Ischemia -- Anatomy -- Strokes and Transient Ischemic Attacks -- Atherosclerosis -- Transient Emboligenic Aortoarteritis -- Subclavian (Cerebral) Steal -- Peripheral Neuropathy -- Mononeuropathies -- Left Recurrent Laryngeal Nerve -- Femoral Nerve -- Obturator Nerve -- Radiculopathies -- Polyneuropathies -- Ischemic Monomelic Neuropathy -- Autonomic Neuropathies -- Anatomy -- Postsympathectomy Neuralgia -- Disorders of Sexual Function -- Aortic Diseases and Surgery -- Aortitis -- Syphilitic Aortitis -- Takayasu Arteritis -- Giant Cell Arteritis -- Aortic Aneurysms -- Nondissecting Aneurysms -- Dissecting Aortic Aneurysms -- Traumatic Aortic Injury -- Coarctation of the Aorta -- Surgery and other Procedures -- Aortic Surgery -- Aortography and other Procedures on the Aorta -- Intraoperative Adjuncts to Avoid Spinal Cord Ischemia -- References -- 3 Neurologic Complications of Cardiac Surgery -- Extracorporeal Circulation -- Technique -- Neurologic Sequelae of Cardiac Surgery -- Acute Brain Disorders -- Peripheral Nerve Disorders -- Neuro-ophthalmologic Disorders -- Neurocognitive Decline. , Risk Factors for Stroke -- Prevention of Neurologic Complications -- Cardiac Transplantation -- References -- 4 Neurologic Complications of Congenital Heart Disease and Cardiac Surgery in Children -- Neurologic Abnormalities before Cardiac Surgery -- Preoperative Neurologic Disorders of Fetal Onset -- Cerebral Dysgenesis -- Chromosomal Disorders -- Preoperative Neurologic Injury of Postnatal Onset -- Neurologic Injury During Cardiac Surgery -- Mechanisms of Intraoperative Brain Injury -- Focal or Multifocal Hypoxic-Ischemic Injury -- Global Hypoxic-Ischemic Injury -- Neurologic Abnormalities in the Postoperative Period -- Mechanisms of Postoperative Brain Injury -- Manifestations of Postoperative Neurologic Dysfunction -- Delayed Recovery of Consciousness -- Postoperative Seizures -- Periventricular White Matter Injury -- Stroke -- Movement Disorders -- Spinal Cord Injury -- Brachial Plexus and Peripheral Nerve Injury -- References -- 5 Neurologic Manifestations of Acquired Cardiac Disease, Arrhythmias, and Interventional Cardiology -- Cardiogenic Embolism -- Clinical Features -- Investigations -- Causes -- Atrial Fibrillation and Flutter -- Cardioversion in Atrial Fibrillation or Flutter -- Chronic Sinoatrial Disorder (Sick Sinus Syndrome) -- Cardiomyopathies -- Myocardial Infarction and Left Ventricular Dysfunction -- Rheumatic Heart Disease -- Atrial Myxoma -- Marantic (Nonbacterial Thrombotic) Endocarditis -- Other Echocardiographic Abnormalities Linked to Stroke -- Patent Foramen Ovale and Atrial Septal Aneurysm -- Left Atrial Spontaneous Echo Contrast -- Mitral Annular Calcification -- Mitral Valve Prolapse -- Aortic Valve Sclerosis and Stenosis -- Acute Medical Treatment of Cardiogenic Embolism -- Syncope -- Interventional Procedures -- Coronary Catheterization -- Percutaneous Transluminal Coronary Angioplasty and Stenting. , Thrombolytic Therapy for Acute Myocardial Infarction -- Acknowledgments -- References -- 6 Neurologic Manifestations of Infective Endocarditis -- Epidemiology of Neurologic Complications -- Pathophysiology of Neurologic Complications -- Risk Factors for Neurologic Complications -- Site of Infection -- Infecting Organism -- Acuteness of Infection -- Valvular Vegetations -- Hematologic Risk Factors -- Ischemic and Hemorrhagic Stroke -- Clinical Presentation -- Seizures -- Evaluation of Patients -- Brain Imaging -- Vascular Imaging -- Cerebrospinal Fluid Examination -- Echocardiography and Stroke -- Treatment of Ischemic Stroke -- Antibiotic Therapy -- Thrombolysis -- Antiplatelet and Anticoagulant Therapy -- Anticoagulation in Native Valve Endocarditis -- Anticoagulation in Prosthetic Valve Endocarditis -- Surgical Treatment -- Treatment of Hemorrhagic Stroke -- Intraparenchymal Hemorrhage -- Mycotic Aneurysms -- Cerebral Infection -- Clinical Presentation -- Evaluation -- Treatment of Cerebral Infection -- Other Neurologic Complications -- Suggested Management Algorithm -- Prognosis -- Concluding Comments -- Acknowledgments -- References -- 7 Neurologic Complications of Hypertension -- Epidemiology -- Pathophysiology -- Evaluation and Treatment -- Stroke -- Cerebral Aneurysms -- Unruptured Cerebral Aneurysms -- Subarachnoid Hemorrhage -- Intracerebral Hemorrhage -- Lacunar Infarct -- Periventricular White Matter Disease -- CADASIL -- Carotid Artery Stenosis -- Intracranial Atherosclerosis -- Aortic Arch Atherosclerosis -- Cardiac Embolus -- Dementia -- Hypertensive Encephalopathy -- Eclampsia -- Immunosuppression -- References -- 8 Postural Hypotension and Syncope -- Non-Neurologic Causes of Postural Hypotension -- Cardiovascular Disorders -- Alterations of Effective Blood Volume -- Drugs -- Endocrine and Metabolic Disorders. , Inadequate Postural Adjustments -- Age -- Autonomic Regulation of the Heart and Blood Vessels -- Neurologic Causes of Postural Hypotension -- Central Lesions and Spinal Injury -- Root and Peripheral Nerve Lesions -- Toxic Exposure -- Primary Degeneration of the Autonomic Nervous System -- Miscellaneous Disorders -- Symptoms of Dysautonomia -- General -- Syncope -- Postural Hypotension -- Neurally Mediated Syncope -- Cardiac Syncope -- Hyperventilation -- Evaluation of Autonomic Function -- Postural Change in Blood Pressure -- Postural Change in Heart Rate -- Valsalva Maneuver -- Other Cardiovascular Responses -- Digital Blood Flow -- Cold Pressor Test -- Norepinephrine Infusion -- Response to Tyramine -- Sweat Tests -- Other Studies -- Pupillary Responses -- Radiologic Studies -- Patient Management -- Treatment -- General Precautions in Dysautonomic Patients -- References -- 9 Neurologic Complications of Cardiac Arrest -- Introduction -- Anoxic-Ischemic Encephalopathy -- Therapeutic Hypothermia -- Prognostic Determination -- Prognostication in the Absence of Therapeutic Hypothermia -- Therapeutic Hypothermia and the Neurologic Examination -- Specifics of the Cardiac Arrest -- Electrophysiologic Tests -- Neuroimaging -- Biomarkers -- Improving Prognostication Accuracy -- Ethical Considerations -- Accurate Prognostication -- Discussion with Substitute Decision-Makers -- References -- 10 Cardiac Manifestations of Acute Neurologic Lesions -- Historical Perspective -- Anatomy and Physiology -- The Insular Cortex -- Ischemic and Hemorrhagic Stroke -- The Electrocardiogram -- QT Prolongation -- Repolarization Abnormalities -- Q Waves and U Waves -- Cardiac Arrhythmias -- Cardiac Injury and Dysfunction -- Plasma Markers -- Epilepsy, Trauma, and other Neurologic Injuries -- Cardiac Evaluation -- Clinical Management -- Concluding Comments -- References. , 11 Stroke as a Complication of General Medical Disorders. , English
    Additional Edition: ISBN 1-336-23401-6
    Additional Edition: ISBN 0-12-407710-2
    Language: English
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  • 2
    Book
    Book
    New York [u.a.] :Churchill Livingstone,
    UID:
    almafu_BV001062251
    Format: XIV, 755 S. : , Ill., zahlr. graph. Darst.
    Edition: 2. ed., 1. publ.
    ISBN: 0-443-08404-1
    Note: Literaturangaben
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Elektroencephalographie ; Neurologie ; Elektrophysiologie ; Elektrodiagnostik ; Neurologie ; Elektrophysiologie ; Diagnose ; Neurologie ; Elektrophysiologie ; Diagnostik
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  • 3
    Online Resource
    Online Resource
    Cambridge : Cambridge University Press
    UID:
    gbv_179008444X
    Format: 1 online resource (xii, 208 pages) , digital, PDF file(s).
    ISBN: 9781009071734 , 9781316513088 , 9781009069991
    Content: Sir Victor Horsley (1857-1916) was a pioneer who shaped the development of neurosurgery and the direction of clinical medicine through his work with the British Medical Association, Medical Defence Union, and General Medical Council. Before the nervous system could be imaged, Horsley operated successfully on the brain and spinal cord, and performed palliative procedures on patients dying from brain tumours. Nevertheless, he became a social pariah due to his support for nationalised health insurance, child welfare and women's rights, amongst other causes. In this fascinating biography, leading neurologist Dr Michael J. Aminoff places Horsley's life and work in the context of the society in which he lived and explores his influence on the development of neurosurgery and social policies still in effect. The many underlying themes to the book include the interplay of science and politics, and the responsibility of physicians to themselves and for the welfare of society.
    Note: Title from publisher's bibliographic system (viewed on 10 Jan 2022)
    Additional Edition: ISBN 9781316513088
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9781316513088
    Language: English
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  • 4
    UID:
    almahu_9948212041302882
    Format: 1 online resource (488 pages).
    ISBN: 0-444-64143-2 , 0-444-64142-4
    Series Statement: Handbook of clinical neurology; Volume 161
    Content: Clinical Neurophysiology: Diseases and Disorders, the latest release in the Handbook of Clinical Neurology series, reviews the current practice of clinical neurophysiology in the laboratory, by the bedside, and in the operating room or intensive care unit. The volume is organized into sections focused on diseases of the central and peripheral nervous systems, sleep disorders, and autonomic disorders. Among the CNS topics covered are epilepsy, altered states of consciousness, disorders of cognition, brain death, demyelinating diseases, stroke, pain, movement disorders, vestibular disease, and auditory disorders. Peripheral nervous system topics include focal mononeuropathies, generalized polyneuropathies, muscle diseases, hyperexcitability states, neuromuscular junction disorders, anterior horn cells diseases, and cranial neuropathies. There are also chapters on sleep apneas, hypersomnias, parasomnias, and circadian rhythm disorders. Autonomic topics include primary autonomic failure, multisystem atrophy, and postural orthostatic tachycardia syndrome.
    Note: Includes index.
    Language: English
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  • 5
    Online Resource
    Online Resource
    Philadelphia :Elsevier Saunders,
    UID:
    almahu_9948026384702882
    Format: 1 online resource (890 p.)
    Edition: 6th ed.
    ISBN: 1-4557-2676-1
    Content: Appropriately select, implement, and interpret electrodiagnostic tests to identify a full range of central and peripheral nervous system disorders with Aminoff's Electrodiagnosis in Clinical Neurology! Covering everything from basic principles to the latest advances in electrodiagnosis, this medical reference book helps you make optimal use of this powerful but complex diagnostic modality in compliance with regulatory and professional standards, so you can diagnose patients accurately and initiate effective treatment and management strategies. Deepen your understanding of the principles, scope, limitations, diagnostic importance, prognostic relevance, and complications for each technique. Visually grasp the technical and practical aspects of electrodiagnostic tests with almost 800 charts, figures, and tables. Rely on the knowledge, experience, and perspective of renowned expert Dr. Michael J. Aminoff and an international team of contributors comprised of a virtual "who's who" of clinical neurophysiology.
    Note: Description based upon print version of record. , English
    Additional Edition: ISBN 1-336-22982-9
    Additional Edition: ISBN 1-4557-0308-7
    Language: English
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  • 6
    UID:
    almahu_9949697622902882
    Format: 1 online resource (677 p.)
    ISBN: 1-283-71654-2 , 0-444-53507-1
    Series Statement: Handbook of clinical neurology ;
    Content: Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological
    Note: Description based upon print version of record. , section 1. Developmental and anatomical perspectives -- section 2. Diagnosis and prognosis -- section 3. Acute spinal cord injury : medical, surgical, and rehabilitative management -- section 4. Chronic spinal cord injury : the changing perspective of neurorestorative rehabilitation, activity-based and surgical restoration therapies -- section 5. Preclinical research : bridging the gap between bench and bedside. , English
    Additional Edition: ISBN 0-444-52137-2
    Language: English
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  • 7
    Online Resource
    Online Resource
    Philadelphia :Churchill Livingstone,
    UID:
    almahu_9948620996802882
    Format: 1 online resource (1307 p.)
    Edition: 4th ed.
    ISBN: 0-7020-3606-4
    Content: Better understand your patients' complete medical profile and provide the best possible care! This one-of-a-kind reference provides a practical look at neurological disease and how it affects, and is affected by, other disease. It helps neurologists manage patients with co-existing medical conditions, and helps internists understand and treat the neurological manifestations of patients' primary diseases. A new emphasis on diagnosis and management-including advances in pharmacology, genetic-based therapies, and new imaging techniques-makes this 4th Edition more clinically valuable than ever!〈ul
    Note: Description based upon print version of record. , Front Cover; Neurology and General Medicine; Copyright Page; Contributors; Preface to the Fourth Edition; Preface to the First Edition; Contents; Chapter 1. Breathing and the Nervous System; RESPIRATORY EFFECTS OF NERVOUS SYSTEM DYSFUNCTION; NERVOUS SYSTEM EFFECTS OF RESPIRATORY DYSFUNCTION; HICCUP; SNEEZING; YAWNING; REFERENCES; Chapter 2. Neurological Complications of Aortic Disease and Surgery; CLINICAL NEUROLOGICAL SYNDROMES DUE TO AORTIC PATHOLOGY; AORTIC DISEASES AND SURGERY; REFERENCES; Chapter 3. Neurological Complications of Cardiac Surgery; EXTRACORPOREAL CIRCULATION , NEUROLOGICAL SEQUELAE OF CARDIAC SURGERYNEUROCOGNITIVE DECLINE; RISK FACTORS FOR STROKE; PREVENTION OF NEUROLOGICAL COMPLICATIONS; CARDIAC TRANSPLANTATION; REFERENCES; Chapter 4. Neurological Complications of Congenital Heart Disease and Cardiac Surgery in Children; NEUROLOGICAL DYSFUNCTION BEFORE CARDIAC SURGERY; MECHANISMS OF NEUROLOGICAL INJURY DURING CARDIAC SURGERY; MANIFESTATIONS OF NEUROLOGICAL DYSFUNCTION IN THE POSTOPERATIVE PERIOD; NEUROLOGICAL COMPLICATIONS OF CARDIAC TRANSPLANTATION; REFERENCES , Chapter 5. Neurological Manifestations of Acquired Cardiac Disease, Arrhythmias, and Interventional CardiologyCARDIOGENIC EMBOLISM; SYNCOPE; INTERVENTIONAL PROCEDURES; REFERENCES; Chapter 6. Neurological Manifestations of Infective Endocarditis; HISTORICAL OVERVIEW; EPIDEMIOLOGY OF NEUROLOGICAL COMPLICATIONS; PATHOPHYSIOLOGY OF NEUROLOGICAL COMPLICATIONS; RISK FACTORS FOR NEUROLOGICAL COMPLICATIONS; ISCHEMIC STROKE; HEMORRHAGIC STROKE; CEREBRAL INFECTION; OTHER NEUROLOGICAL COMPLICATIONS; SUGGESTED MANAGEMENT ALGORITHM; PROGNOSIS; CONCLUDING COMMENTS; ACKNOWLEDGMENTS; REFERENCES , Chapter 7. Neurological Complications of HypertensionEPIDEMIOLOGY; PATHOPHYSIOLOGY; EVALUATION AND TREATMENT; STROKE; CEREBRAL ANEURYSMS; INTRACEREBRAL HEMORRHAGE; LACUNAR INFARCT; PERIVENTRICULAR WHITE MATTER DISEASE; BINSWANGER'S DISEASE; CADASIL; CAROTID ARTERY STENOSIS; INTRACRANIAL ATHEROSCLEROSIS; AORTIC ARCH ATHEROSCLEROSIS; CARDIAC EMBOLUS; DEMENTIA; PERIPHERAL NEUROPATHY; HYPERTENSIVE ENCEPHALOPATHY; ECLAMPSIA; IMMUNOSUPPRESSION; REFERENCES; Chapter 8. Postural Hypotension; NON-NEUROLOGICAL CAUSES OF POSTURAL HYPOTENSION; AUTONOMIC REGULATION OF THE HEART AND BLOOD VESSELS , NEUROLOGICAL CAUSES OF POSTURAL HYPOTENSIONSYMPTOMS OF DYSAUTONOMIA; EVALUATION OF AUTONOMIC FUNCTION; PATIENT MANAGEMENT; REFERENCES; Chapter 9. Neurological Complications of Cardiac Arrest; VIEW OF THE PAST; OUTCOMES OF CARDIAC ARREST; PREDICTING OUTCOMES OF CARDIAC ARREST; ALTERATION OF OUTCOMES; VIEW TO THE FUTURE; REFERENCES; Chapter 10. Cardiac Manifestations of Acute Neurological Lesions; HISTORICAL PERSPECTIVE; ISCHEMIC AND HEMORRHAGIC STROKE; EPILEPSY AND OTHER NEUROLOGICAL DISORDERS; CARDIAC EVALUATION; CLINICAL MANAGEMENT; CONCLUDING COMMENTS; REFERENCES , Chapter 11. Neurocutaneous Syndromes , English
    Additional Edition: ISBN 0-443-06707-4
    Language: English
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  • 8
    UID:
    almahu_9948025672302882
    Format: 1 online resource (471 p.)
    ISBN: 1-283-60841-3 , 9786613920867 , 0-444-53495-4
    Series Statement: Handbook of clinical neurology ; 3rd ser., v. 104
    Content: This volume highlights recent developments in neuro-oncology that are not only increasing the survival rate of patients, but also improving their quality of life. Through an in-depth exploration of new therapies, including advanced diagnostic tools and a fresh perspective on molecular biology, immunology, and the clinical aspects of tumors, clinicians will gain a critical understanding of emerging therapies and techniques. Extensive coverage of tumor management and new therapeutic strategies, including gene therapy and molecularly targeted treatments are also explored, providing clinicians
    Note: Description based upon print version of record. , Front Cover; Neuro-Oncology; Copyright; Available titles; Foreword; Preface; List of contributors; Contents of Part I; Contents of Part II; Section 1: Basic Principles; Chapter 1: Epidemiology of primary central nervous system tumors; Introduction; Descriptive Epidemiology Of adult Malignant and Nonmalignant Central Nervous System Tumors; Incidence and Mortality; Temporal Trends; Survival; Descriptive Epidemiology of Childhood Central Nervous System Tumors; Incidence and Mortality; Temporal Trends; Survival; Genetic Epidemiology; Genetic Syndromes; Familial Aggregation , Molecular Genetic InvestigationsEnvironmental Exposures; Ionizing Radiation; Electromagnetic Fields; Mobile Phones; Smoking; Diet; Occupation; Medications; Beauty Products; Allergy; Infectious Agents; References; Chapter 2: Molecular biology of brain tumors; Introduction; Genetic Alterations and Pathogenesis in Gliomas; Diffuse Astrocytoma; Diffuse Astrocytoma to Anaplastic Astrocytoma; Transition From Anaplastic Astrocytoma To glioblastoma Multiforme; Oligodendroglial Tumors; Predictive and Prognostic Molecular Markers in Glioma; Predictive Versus Prognostic , Methylguanine-Dna Methyltransferase MethylationEpidermal Growth Factor Receptor and Phosphoinositide 3-kinase Pathway; Ykl-40; Chromosome 1p/19q Deletion In oligodendroglioma; Proliferation Markers; Microarray Profiling; Microarray Technology; Microarray Profiling Identifies Molecular Subsets of Glioma; Molecular Genetics of Meningioma; Benign/grade I Meningioma; Anaplastic/grade Iii Meningioma; Summary; References; Chapter 3: Angiogenesis and invasion in cancer; Introduction; Basic Mechanisms of Vascular development; The Angiogenic Switch; Key Players in the Angiogenic Process , Lymphangiogenesis: a New Field In angiogenesis ResearchGeneral Aspects of Tumor Angiogenesis and Lymphangiogenesis; Angiogenesis and Brain Malignancy; Invasion and Its Relation To angiogenesis in Malignant Brain Tumors; Fibronectin; Proteases and Their Inhibitors; c-Met; References; Chapter 4: Immunology of brain tumors; Introduction; General Principles of Immunology; Immunology in the Central Nervous System; Interactions of Tumor Cells With immune Cells; The Controversial Role Of microglial Cells; Tumor-derived Immunosuppression; Transforming Growth Factor-beta , Nonclassical Major Histocompatibility Complex Class I MoleculesFurther Immunosuppressive Factors; Summary and Conclusions; References; Chapter 5: Blood-brain barrier and brain edema; The Blood-brain Barrier; Physiology of the Blood-brain Barrier; Circumventing the Blood-brain Barrier; Brain Tumor Edema; Pathophysiology of Brain Tumor Edema; Tumor-specific Aspects of Edema; Therapy-associated Brain Tumor Edema; Clinical Presentation of Brain Tumor Edema; Imaging of Brain Tumor Edema; Management of Brain Tumor Edema; Complications of Edema Therapy; References; Chapter 6: Stem cells in gliomas , The Identity of Neural Stem Cells changes With Developmental Time , English
    Additional Edition: ISBN 0-444-52138-0
    Language: English
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  • 9
    UID:
    almahu_9949697678102882
    Format: 1 online resource (549 p.)
    ISBN: 1-283-60832-4 , 9786613920775 , 0-444-53503-9
    Series Statement: Handbook of clinical neurology ; 3rd ser., v.105
    Content: This volume provides unique insights into the field of neuro-oncology by presenting new advancements and research in the study and treatment of tumors of the nervous system, their progression, side effects, and the adverse effects of some therapies. An in-depth exploration of the management of tumors and new therapeutic strategies is extensively covered, including groundbreaking research on gene therapy and molecularly targeted treatments. Clinicians will gain a better understanding of the many neurological manifestations of tumors through a thorough analysis of recent developments
    Note: Description based upon print version of record. , Front Cover; Neuro-Oncology; Copyright; Available titles; Foreword; Preface; List of contributors; Contents of Part II; Contents of Part I; Section 4: Specific Tumor Types; Chapter 29: Low-grade gliomas; Introduction; Epidemiology; Pathology and Molecular Genetics; Clinical Presentation and Neuroimaging; Natural History and Prognostic factors; Antiepileptic Drug Treatment; Surgery; Radiotherapy; Chemotherapy; New Developments; Conclusion; References; Chapter 30: Anaplastic astrocytomas; Introduction; Epidemiology and Prognosis; Epidemiology; Prognosis; Risk Factors and Etiology , Familial FactorsEnvironmental Factors; Mutations; Pathology; Clinical Presentation; Imaging; Management; Initial Management; Surgical Resection; Radiation Therapy; Adjuvant Chemotherapy; Neoadjuvant Chemotherapy; Concurrent and Adjuvant Chemotherapy; Treatment At Recurrence; Reoperation; Reirradiation; Salvage Chemotherapy; Targeted Therapy; Future Directions; References; Chapter 31: Anaplastic oligodendroglial tumors; Introduction; Clinical Presentation And localization; Pathology, Genetics, and Biology; Histology; Genetics; Genetics and Pathology; Genetics and Tumor Localization , EpigeneticsDiagnosis; Prognosis; Treatment; The Wait-and-see Policy in Low-grade Oligodendroglial Tumors; Surgery; Postsurgical Adjuvant Treatment; Radiotherapy; Chemotherapy; Chemotherapy in Recurrent Disease; Pcv Or Tmz: Which Regimen to Prefer?; Second-line Treatment With Pcv Or Tmz; Second-line Treatment With Other Agents; Antiangiogenesis Agents; Adjuvant Chemotherapy in Newly Diagnosed Aoa and Aod; Upfront Chemotherapy in Newly Diagnosed Aod; Upfront Chemotherapy in Low-grade Od; Conclusion; References; Chapter 32: Glioblastoma; Introduction; Epidemiology and Tumor Grading , Molecular Pathways of GliomagenesisPrognosis and Prognostic Factors; Diagnosis; Clinical Presentation; Diagnostic Evaluation; Treatment Modalities; Introduction; Surgery; Extent of Surgical Resection and Prognosis; Delivery of Local Therapies; The Role of Surgery for Recurrent Disease; Radiation Therapy; Chemotherapy; Early Trials: the Debated Role Of chemotherapy; The New Standard of Care for Newly Diagnosed Glioblastoma; Targeted Therapies and Other New Approaches to Treatment; Rationale for the Development of Targeted therapies; Targeted Therapies: Current Results And challenges , Other New Approaches to TreatmentManagement of Symptoms; Brain Edema; Seizures; Fatigue and Cognitive Dysfunction; Venous Thromboembolism; Pneumocystis Jirovecii Pneumonia; Conclusion; References; Chapter 33: Gliomatosis cerebri; Introduction and Definition; Epidemiology; Clinical Presentation; Diagnostic Workup; Pathological and Molecular Findings; Therapy; Natural Course and Prognostic Factors; Radiotherapy; Chemotherapy; Future Perspective; References; Chapter 34: Primary central nervous system lymphoma; Introduction; Primary Central Nervous System Lymphoma in Immunocompetent Patients , Epidemiology , English
    Additional Edition: ISBN 0-444-53502-0
    Language: English
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  • 10
    Online Resource
    Online Resource
    Amsterdam, Netherlands :Elsevier,
    UID:
    almahu_9949698035502882
    Format: 1 online resource (634 p.)
    ISBN: 0-444-63541-6
    Series Statement: Handbook of Clinical Neurology ; Volume 126
    Content: This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson's disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system. * Offers a unique emphasis on the neurological manifestations of diabetes * Provides thorough coverage of the clinical, experimental, mechanistic, therapeutic, peripheral, and central aspects of diabetic neuropathy
    Note: "3rd Series." , Front Cover; Diabetes and the Nervous System; Copyright; Handbook of Clinical Neurology 3rd Series; Foreword; Preface; Contributors; Contents; Section 1: Clinical Impact of Diabetes on the Nervous System; Chapter 1: Epidemiology of Polyneuropathy in Diabetes and Prediabetes; Introduction; Clinical Impact of Diabetic Distal Symmetric Sensorimotor Polyneuropathy; Testing for Peripheral Neuropathy; Painful Neuropathy; Population Selection; Prevalence in Diabetes; Prevalence in Prediabetes; Impaired Fasting Glucose or Impaired Glucose Tolerance to Diagnose Prediabetes? , Neuropathy in People With PrediabetesIncidence and Natural History of diabetic Polyneuropathy; Etiologic Factors Related to diabetic Neuropathy; Hyperglycemia; Role of Intensive Diabetes Therapy in Prevention and Progression of Diabetic Neuropathy; Diabetes Duration; Age; Height; Hypoinsulinemia; Cardiovascular Risk Factors; Hypertension; Lipids; Obesity; Smoking; Alcohol Consumption; Depression; Genetic Factors; Conclusions; Chapter 2: Clinical Features of Diabetic Polyneuropathy; Early Studies of the Clinical Features of Diabetic Polyneuropathy; Symptoms of Diabetic Polyneuropathy , Clinical Signs of Diabetic PolyneuropathyAbbreviated Forms of Assessment; Subtypes of Diabetic Polyneuropathy; Distinguishing Diabetic Polyneuropathy From Other Polyneuropathies; Conclusions; References; Chapter 3: Focal and Entrapment Neuropathies; Introduction; Cranial Mononeuropathies; Oculomotor, Trochlear, and Abducens Neuropathies; Anatomy and Pathophysiology; Literature and Epidemiology; Clinical Presentation; Laboratory/radiology Findings; Differential Diagnosis; Management and Prognosis; Facial Neuropathy; Anatomy and Pathophysiology; Literature and Epidemiology , Clinical PresentationLaboratory/radiology Findings; Differential Diagnosis; Management and Prognosis; Malignant Cranial Nerve Syndromes; Rhinocerebral Mucormycosis; Malignant Otitis Externa; Other Cranial Nerve Syndromes; Upper Limb Mononeuropathies; Median Neuropathies: Carpal Tunnel Syndrome; Anatomy and Pathophysiology; Literature and Epidemiology; Clinical Presentation/differential Diagnosis; Laboratory/radiology Findings; Management; Ulnar Neuropathies: Ulnar Neuropathy At the elbow; Other Upper Limb Mononeuropathies; Truncal Mononeuropathies; Thoracic Monoradiculopathy , Phrenic MononeuropathyLower Limb Mononeuropathies; Lateral Femoral Cutaneous Neuropathy; Fibular (peroneal) Mononeuropathy; Other Lower Limb Mononeuropathies; Conclusion; References; Chapter 4: Diabetic Radiculoplexus Neuropathies; Introduction; Clinical Features of the Diabetic Radiculoplexus Neuropathies; Epidemiology; Etiology and Pathogenesis; Treatment; Conclusion; References; Chapter 5: Painful Diabetic Neuropathy: Clinical Aspects; Introduction; Epidemiology of Painful Diabetic neuropathy; Pathogenesis of Neuropathic pain; Early Diagnosis and Intervention in Painful Neuropathy , Symptoms and Signs of Painful Diabetic Neuropathy , English
    Additional Edition: ISBN 0-444-53480-6
    Language: English
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