Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (605 p.)

Edition: 1st ed.

ISBN: 1-4377-1123-5

Uniform Title: Braunwald's heart disease.

Content: From basic science to pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options, this new title in the Braunwald's Heart Disease family offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style.

Note: "An Expert Consult title"--Cover. , SECTION I: BASIC MECHANISMS; CHAPTER 1. Human Plasma Lipoprotein Metabolism; THE LIPOPROTEINS; LIPOPROTEIN PROPERTIES; LIPOPROTEIN PRODUCTION; REFERENCES; CHAPTER 2. Regulation and Clearance of Apolipoprotein B-Containing Lipoproteins; INTRODUCTION; APOLIPOPROTEIN B STRUCTURE; APOLIPOPROTEIN B GENE REGULATION AND EDITING , PROTEASOMAL AND NONPROTEASOMAL DEGRADATION OF APOLIPOPROTEIN BASSEMBLY OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; PLASMA METABOLISM OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; EMERGING TARGETS FOR REDUCING PLASMA LEVELS OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; REFERENCES; CHAPTER 3. Absorption and Excretion of Cholesterol and Other Sterols; INTRODUCTION; PHYSICAL-CHEMICAL PROPERTIES AND COMPOSITIONS OF INTESTINAL LIPIDS DERIVED FROM THE DIET AND FROM BILE; SOURCES OF INTESTINAL STEROLS; MOLECULAR PHYSIOLOGY OF INTESTINAL CHOLESTEROL ABSORPTION; FECAL EXCRETION OF INTESTINAL STEROLS , GENETIC ANALYSIS OF INTESTINAL CHOLESTEROL ABSORPTIONFACTORS THAT INFLUENCE INTESTINAL CHOLESTEROL ABSORPTION EFFICIENCY; INHIBITORS OF INTESTINAL CHOLESTEROL ABSORPTION; CONCLUSIONS; REFERENCES; CHAPTER 4. High-Density Lipoprotein Metabolism; INTRODUCTION; HIGH-DENSITY LIPOPROTEINS; CLASSIFICATION OF HIGH-DENSITY LIPOPROTEINS; SYNTHESIS OF HIGH-DENSITY LIPOPROTEIN APOLIPOPROTEIN A-I AND APOLIPOPROTEIN A-II; HIGH-DENSITY LIPOPROTEIN AND CHOLESTEROL EFFLUX; SCHEMATIC OVERVIEW OF HIGH-DENSITY LIPOPROTEIN METABOLISM AND REVERSE CHOLESTEROL METABOLISM; REGULATION OF HEPATIC CHOLESTEROL , REGULATION OF THE PLASMA LEVEL OF HIGH-DENSITY LIPOPROTEINHIGH-DENSITY LIPOPROTEIN METABOLISM; CONCLUSIONS; REFERENCES; CHAPTER 5. Lipoproteins: Mechanisms for Atherogenesis and Progression of Atherothrombotic Disease; INTRODUCTION; INFLAMMATION: A FINAL COMMON PATH THAT LINKS MANY RISK FACTORS TO ATHEROGENESIS; LIPOPROTEINS AND THE INITIATION OF ATHEROSCLEROSIS: RESPONSE TO LOW-DENSITY LIPOPROTEIN RETENTION AND BEYOND; HIGH-DENSITY LIPOPROTEIN: THE ANTIATHEROGENIC LIPOPROTEIN; FATTY STREAK FORMATION; LINKS BETWEEN LIPIDS AND LESION PROGRESSION , ATHEROTHROMBOSIS: THE COMPLICATIONS OF THE ATHEROSCLEROTIC PLAQUEEFFECTS OF LIPID LOWERING ON THE ATHEROSCLEROTIC PLAQUE; PERSPECTIVES ON LINKS BETWEEN LIPOPROTEINS AND MECHANISMS OF ATHEROSCLEROSIS; REFERENCES; CHAPTER 6. Genetic Dyslipidemia; INTRODUCTION; COMMON GENETIC DISORDERS OF LIPOPROTEIN METABOLISM; SUMMARY AND CONCLUSIONS; REFERENCES; CHAPTER 7. High-Density Lipoprotein Mutations; HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS IN POPULATIONS; IMPACT OF GENES ON HIGH-DENSITY LIPOPROTEIN CHOLESTEROL; INBORN ERRORS OF HIGH-DENSITY LIPOPROTEIN METABOLISM; REFERENCES , CHAPTER 8. Lipoprotein Oxidation and Modification , English

Additional Edition: ISBN 1-4160-5469-3

Language: English

UID:

Format: 1 online resource (390 pages) : , color illustrations

Edition: Third edition.

ISBN: 0-323-88286-2 , 0-323-88287-0

Content: Part of the renowned Braunwald family of references, Clinical Lipidology: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on the therapeutic management of patients with high cholesterol levels and other atherogenic lipid disorders. An invaluable resource for cardiologists, lipidologists, endocrinologists, and internal medicine physicians, this one-stop reference covers everything from basic science and the pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options. Now fully updated from cover to cover, the 3rd Edition offers unparalleled coverage of lipidology in an accessible and user-friendly manner.

Note: Preceded by: Clinical lipidology / Christie M. Ballantyne. 2nd ediion. [2015] , Complemented by: Braunwald's heart disease / edited by Leonard S. Lilly. 12th edition. [2023]. , Overview of Lipids and Atherosclerosis -- Overview of Risk Assessment -- Measurement of Low-Density Lipoprotein Cholesterol, Non-High--- Density Lipoprotein Cholesterol, Apolipoprotein B, and Low-Density -- Lipoprotein Particle Concentration -- Triglycerides, Triglyceride-Rich Lipoproteins, and High-Density -- Lipoprotein in Coronary Heart Disease Risk Assessment -- Lipoprotein(a) in Cardiovascular Risk Assessment -- Clinical Evaluation for Genetic Testing and Secondary Causes of -- Dyslipidemia -- Polygenic Risk Scores -- High-Sensitivity C-Reactive Protein -- Emerging Assays for Risk Assessment -- Imaging Atherosclerosis for Risk Stratification : Cardiac Computed -- Tomography and Carotid Ultrasound -- Overview of General Approach to Management of Dyslipidemias -- Treatment Guidelines Overview : American Heart -- Association/American College of Cardiology/Multisociety Guideline and Updates -- Treatment Guidelines Overview : European Society of -- Cardiology/European Atherosclerosis Society Guidelines -- Dietary Patterns for the Prevention and Treatment of Cardiovascular Disease -- Updated Clinical Guide to Exercise and Lipids -- Obesity, Lipids, and Cardiovascular Disease -- Statins -- Cholesterol Absorption Inhibitors -- Omega-3 Fatty Acids -- Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition -- Inclisiran -- Bempedoic Acid -- Pemafibrate : A New Selective Peroxisome Proliferator-Activated -- Receptor-α Modulator for Hypertriglyceridemia Management -- Anti-inflammatory Therapy for Cardiovascular Disease -- Nutraceuticals and Functional Foods for Cholesterol Reduction -- Evolving Therapeutic Targets : Lipoprotein(a) -- Inhibition of ANGPTL3 as a Target for Treating Dyslipidemias -- Evolving Therapeutic Targets : Apolipoprotein C-III -- Evolving Therapeutic Targets : Cholesteryl Ester Transfer Protein Inhibition -- Gene Therapy and Therapeutic Genome Editing in Liver for Lipid Disorders -- Special Patient Populations : Diabetes and Metabolic Syndrome -- Special Patient Populations : Women and Older Adults -- Special Patient Populations : Children and Adolescents -- Special Patient Populations : Familial Hypercholesterolemia and -- Other Severe Hypercholesterolemias -- Special Patient Populations : Treatment of Familial -- Chylomicronemia Syndrome and Sustained Chylomicronemia -- Special Patient Populations : Acute Coronary Syndromes -- Special Patient Populations : Transplant Recipients -- Special Populations : Chronic Kidney Disease -- Special Patient Populations : Lipid Abnormalities in High-Risk -- Racial/Ethnic Groups -- Persons With Human Immunodeficiency Virus.

Language: English

UID:

Format: 1 online resource (571 p.)

Edition: 2nd ed.

ISBN: 0-323-31326-4

Series Statement: Companion to Braunwald's Heart Disease

Uniform Title: Braunwald's heart disease. 10th ed.

Content: 〈b〉〈i〉Clinical Lipidology,〈/i〉〈/b〉 a companion to 〈b〉〈i〉Braunwald's Heart Disease, 〈/b〉〈/i〉is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers 〈b〉unparalleled coverage and expert guidance on lipidology〈/b〉 in a straightforward, accessible, and user-friendly style. 〈ul〉〈b〉〈li〉Get authoritative guidance〈/b〉 from some of the foremost experts in the field.〈/li〉〈li〉〈b〉Easily access key c

Note: Complemented by: Braunwald's heart disease / edited by Douglas L. Mann, Douglas P. Zipes, Peter Libby, Robert O. Bonow, Eugene Braunwald. 10th edition. [2015]. , Front Cover; Inside Front Cover; Clinical Lipidology: A Companion to Braunwald's Heart Disease; Copyright; Dedication; Contributors; Preface; Contents; Section I: Basic Mechanisms; Chapter 1: Human Plasma Lipoprotein Metabolism; The lipoproteins; Introduction; Lipoprotein compositions and properties; The Apolipoproteins; Lipoprotein production; Triglyceride-Rich Lipoproteins; Intermediate-Density Lipoproteins and Low-Density Lipoproteins; High-Density Lipoproteins; Lipoprotein remodeling and catabolism; Reverse Cholesterol Transport; Lecithin:Cholesterol Acyltransferase , Lipid Transfer ProteinsLipases in Lipid and Lipoprotein Metabolism; High-Density Lipoprotein-Apo Lipoprotein A-I Stability and Metabolism; Metabolic syndrome and more; The high-density lipoprotein hypothesis: pros and cons of high-density lipoprotein therapy; Future challenges; References; Chapter 2: Regulation and Clearance of Apolipoprotein B-Containing Lipoproteins; Introduction; Apolipoprotein B structure; Apolipoprotein B gene regulation and editing; Apolipoprotein B-48 Production by Messenger Ribonucleic Acid Editing , Mutations in the APOB Gene Cause Monogenic Hyper- and HypocholesterolemiaInsights into Apolipoprotein B Expression Derived from Human Apolipoprotein B-100-Transgenic Mice; Insights into Apolipoprotein B Biology from Gene-Targeting Studies in Mice; Co and Posttranslational Regulation; Proteasomal and nonproteasomal degradation of apolipoprotein B; Autophagy and apolipoprotein B-100 degradation; Assembly of apolipoprotein B-containing lipoproteins; Plasma metabolism of apolipoprotein B-containing lipoproteins; Processing of Remnant Lipoproteins , Hepatic Uptake of Remnants of Apolipoprotein B-Containing LipoproteinsEmerging targets for reducing plasma levels of apolipoprotein B-containing lipoproteins; Acknowledgements; References; Chapter 3: Absorption and Excretion of Intestinal Cholesterol and Other Sterols; Introduction; Physical-chemical properties and compositions of intestinal lipids derived from the diet and from bile; Balance of intestinal lipids; Sources of intestinal sterols; Molecular physiology of intestinal cholesterol absorption; Intraluminal Digestion of Lipids; Intestinal Uptake of Sterols , Intracellular Metabolism of Absorbed LipidsAssembly and Secretion of Intestinal Lipoproteins; Fecal excretion of intestinal sterols; Genetic Control of intestinal cholesterol absorption; Factors that influence intestinal cholesterol absorption efficiency; Inhibitors of intestinal cholesterol absorption; Plant Sterols and Stanols (Phytosterols); Ezetimibe; Bile Acids; Conclusions; Acknowledgements; References; Chapter 4: High-Density Lipoprotein Metabolism; Introduction; High-density lipoproteins; Classification of high-density lipoproteins , High-density lipoproteins and reverse cholesterol transport , English

Additional Edition: ISBN 0-323-28786-7

Language: English

UID:

Format: 1 online resource (571 p.)

Edition: 2nd ed.

ISBN: 0-323-31326-4

Series Statement: Companion to Braunwald's Heart Disease

Uniform Title: Braunwald's heart disease. 10th ed.

Content: 〈b〉〈i〉Clinical Lipidology,〈/i〉〈/b〉 a companion to 〈b〉〈i〉Braunwald's Heart Disease, 〈/b〉〈/i〉is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers 〈b〉unparalleled coverage and expert guidance on lipidology〈/b〉 in a straightforward, accessible, and user-friendly style. 〈ul〉〈b〉〈li〉Get authoritative guidance〈/b〉 from some of the foremost experts in the field.〈/li〉〈li〉〈b〉Easily access key c

Note: Complemented by: Braunwald's heart disease / edited by Douglas L. Mann, Douglas P. Zipes, Peter Libby, Robert O. Bonow, Eugene Braunwald. 10th edition. [2015]. , Front Cover; Inside Front Cover; Clinical Lipidology: A Companion to Braunwald's Heart Disease; Copyright; Dedication; Contributors; Preface; Contents; Section I: Basic Mechanisms; Chapter 1: Human Plasma Lipoprotein Metabolism; The lipoproteins; Introduction; Lipoprotein compositions and properties; The Apolipoproteins; Lipoprotein production; Triglyceride-Rich Lipoproteins; Intermediate-Density Lipoproteins and Low-Density Lipoproteins; High-Density Lipoproteins; Lipoprotein remodeling and catabolism; Reverse Cholesterol Transport; Lecithin:Cholesterol Acyltransferase , Lipid Transfer ProteinsLipases in Lipid and Lipoprotein Metabolism; High-Density Lipoprotein-Apo Lipoprotein A-I Stability and Metabolism; Metabolic syndrome and more; The high-density lipoprotein hypothesis: pros and cons of high-density lipoprotein therapy; Future challenges; References; Chapter 2: Regulation and Clearance of Apolipoprotein B-Containing Lipoproteins; Introduction; Apolipoprotein B structure; Apolipoprotein B gene regulation and editing; Apolipoprotein B-48 Production by Messenger Ribonucleic Acid Editing , Mutations in the APOB Gene Cause Monogenic Hyper- and HypocholesterolemiaInsights into Apolipoprotein B Expression Derived from Human Apolipoprotein B-100-Transgenic Mice; Insights into Apolipoprotein B Biology from Gene-Targeting Studies in Mice; Co and Posttranslational Regulation; Proteasomal and nonproteasomal degradation of apolipoprotein B; Autophagy and apolipoprotein B-100 degradation; Assembly of apolipoprotein B-containing lipoproteins; Plasma metabolism of apolipoprotein B-containing lipoproteins; Processing of Remnant Lipoproteins , Hepatic Uptake of Remnants of Apolipoprotein B-Containing LipoproteinsEmerging targets for reducing plasma levels of apolipoprotein B-containing lipoproteins; Acknowledgements; References; Chapter 3: Absorption and Excretion of Intestinal Cholesterol and Other Sterols; Introduction; Physical-chemical properties and compositions of intestinal lipids derived from the diet and from bile; Balance of intestinal lipids; Sources of intestinal sterols; Molecular physiology of intestinal cholesterol absorption; Intraluminal Digestion of Lipids; Intestinal Uptake of Sterols , Intracellular Metabolism of Absorbed LipidsAssembly and Secretion of Intestinal Lipoproteins; Fecal excretion of intestinal sterols; Genetic Control of intestinal cholesterol absorption; Factors that influence intestinal cholesterol absorption efficiency; Inhibitors of intestinal cholesterol absorption; Plant Sterols and Stanols (Phytosterols); Ezetimibe; Bile Acids; Conclusions; Acknowledgements; References; Chapter 4: High-Density Lipoprotein Metabolism; Introduction; High-density lipoproteins; Classification of high-density lipoproteins , High-density lipoproteins and reverse cholesterol transport , English

Additional Edition: ISBN 0-323-28786-7

Language: English

UID:

Format: 1 online resource (571 p.)

Edition: 2nd ed.

ISBN: 0-323-31326-4

Series Statement: Companion to Braunwald's Heart Disease

Uniform Title: Braunwald's heart disease. 10th ed.

Content: 〈b〉〈i〉Clinical Lipidology,〈/i〉〈/b〉 a companion to 〈b〉〈i〉Braunwald's Heart Disease, 〈/b〉〈/i〉is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers 〈b〉unparalleled coverage and expert guidance on lipidology〈/b〉 in a straightforward, accessible, and user-friendly style. 〈ul〉〈b〉〈li〉Get authoritative guidance〈/b〉 from some of the foremost experts in the field.〈/li〉〈li〉〈b〉Easily access key c

Note: Complemented by: Braunwald's heart disease / edited by Douglas L. Mann, Douglas P. Zipes, Peter Libby, Robert O. Bonow, Eugene Braunwald. 10th edition. [2015]. , Front Cover; Inside Front Cover; Clinical Lipidology: A Companion to Braunwald's Heart Disease; Copyright; Dedication; Contributors; Preface; Contents; Section I: Basic Mechanisms; Chapter 1: Human Plasma Lipoprotein Metabolism; The lipoproteins; Introduction; Lipoprotein compositions and properties; The Apolipoproteins; Lipoprotein production; Triglyceride-Rich Lipoproteins; Intermediate-Density Lipoproteins and Low-Density Lipoproteins; High-Density Lipoproteins; Lipoprotein remodeling and catabolism; Reverse Cholesterol Transport; Lecithin:Cholesterol Acyltransferase , Lipid Transfer ProteinsLipases in Lipid and Lipoprotein Metabolism; High-Density Lipoprotein-Apo Lipoprotein A-I Stability and Metabolism; Metabolic syndrome and more; The high-density lipoprotein hypothesis: pros and cons of high-density lipoprotein therapy; Future challenges; References; Chapter 2: Regulation and Clearance of Apolipoprotein B-Containing Lipoproteins; Introduction; Apolipoprotein B structure; Apolipoprotein B gene regulation and editing; Apolipoprotein B-48 Production by Messenger Ribonucleic Acid Editing , Mutations in the APOB Gene Cause Monogenic Hyper- and HypocholesterolemiaInsights into Apolipoprotein B Expression Derived from Human Apolipoprotein B-100-Transgenic Mice; Insights into Apolipoprotein B Biology from Gene-Targeting Studies in Mice; Co and Posttranslational Regulation; Proteasomal and nonproteasomal degradation of apolipoprotein B; Autophagy and apolipoprotein B-100 degradation; Assembly of apolipoprotein B-containing lipoproteins; Plasma metabolism of apolipoprotein B-containing lipoproteins; Processing of Remnant Lipoproteins , Hepatic Uptake of Remnants of Apolipoprotein B-Containing LipoproteinsEmerging targets for reducing plasma levels of apolipoprotein B-containing lipoproteins; Acknowledgements; References; Chapter 3: Absorption and Excretion of Intestinal Cholesterol and Other Sterols; Introduction; Physical-chemical properties and compositions of intestinal lipids derived from the diet and from bile; Balance of intestinal lipids; Sources of intestinal sterols; Molecular physiology of intestinal cholesterol absorption; Intraluminal Digestion of Lipids; Intestinal Uptake of Sterols , Intracellular Metabolism of Absorbed LipidsAssembly and Secretion of Intestinal Lipoproteins; Fecal excretion of intestinal sterols; Genetic Control of intestinal cholesterol absorption; Factors that influence intestinal cholesterol absorption efficiency; Inhibitors of intestinal cholesterol absorption; Plant Sterols and Stanols (Phytosterols); Ezetimibe; Bile Acids; Conclusions; Acknowledgements; References; Chapter 4: High-Density Lipoprotein Metabolism; Introduction; High-density lipoproteins; Classification of high-density lipoproteins , High-density lipoproteins and reverse cholesterol transport , English

Additional Edition: ISBN 0-323-28786-7

Language: English

UID:

Format: 1 online resource (605 p.)

Edition: 1st ed.

ISBN: 1-4377-1123-5

Uniform Title: Braunwald's heart disease.

Content: From basic science to pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options, this new title in the Braunwald's Heart Disease family offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style.

Note: "An Expert Consult title"--Cover. , SECTION I: BASIC MECHANISMS; CHAPTER 1. Human Plasma Lipoprotein Metabolism; THE LIPOPROTEINS; LIPOPROTEIN PROPERTIES; LIPOPROTEIN PRODUCTION; REFERENCES; CHAPTER 2. Regulation and Clearance of Apolipoprotein B-Containing Lipoproteins; INTRODUCTION; APOLIPOPROTEIN B STRUCTURE; APOLIPOPROTEIN B GENE REGULATION AND EDITING , PROTEASOMAL AND NONPROTEASOMAL DEGRADATION OF APOLIPOPROTEIN BASSEMBLY OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; PLASMA METABOLISM OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; EMERGING TARGETS FOR REDUCING PLASMA LEVELS OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; REFERENCES; CHAPTER 3. Absorption and Excretion of Cholesterol and Other Sterols; INTRODUCTION; PHYSICAL-CHEMICAL PROPERTIES AND COMPOSITIONS OF INTESTINAL LIPIDS DERIVED FROM THE DIET AND FROM BILE; SOURCES OF INTESTINAL STEROLS; MOLECULAR PHYSIOLOGY OF INTESTINAL CHOLESTEROL ABSORPTION; FECAL EXCRETION OF INTESTINAL STEROLS , GENETIC ANALYSIS OF INTESTINAL CHOLESTEROL ABSORPTIONFACTORS THAT INFLUENCE INTESTINAL CHOLESTEROL ABSORPTION EFFICIENCY; INHIBITORS OF INTESTINAL CHOLESTEROL ABSORPTION; CONCLUSIONS; REFERENCES; CHAPTER 4. High-Density Lipoprotein Metabolism; INTRODUCTION; HIGH-DENSITY LIPOPROTEINS; CLASSIFICATION OF HIGH-DENSITY LIPOPROTEINS; SYNTHESIS OF HIGH-DENSITY LIPOPROTEIN APOLIPOPROTEIN A-I AND APOLIPOPROTEIN A-II; HIGH-DENSITY LIPOPROTEIN AND CHOLESTEROL EFFLUX; SCHEMATIC OVERVIEW OF HIGH-DENSITY LIPOPROTEIN METABOLISM AND REVERSE CHOLESTEROL METABOLISM; REGULATION OF HEPATIC CHOLESTEROL , REGULATION OF THE PLASMA LEVEL OF HIGH-DENSITY LIPOPROTEINHIGH-DENSITY LIPOPROTEIN METABOLISM; CONCLUSIONS; REFERENCES; CHAPTER 5. Lipoproteins: Mechanisms for Atherogenesis and Progression of Atherothrombotic Disease; INTRODUCTION; INFLAMMATION: A FINAL COMMON PATH THAT LINKS MANY RISK FACTORS TO ATHEROGENESIS; LIPOPROTEINS AND THE INITIATION OF ATHEROSCLEROSIS: RESPONSE TO LOW-DENSITY LIPOPROTEIN RETENTION AND BEYOND; HIGH-DENSITY LIPOPROTEIN: THE ANTIATHEROGENIC LIPOPROTEIN; FATTY STREAK FORMATION; LINKS BETWEEN LIPIDS AND LESION PROGRESSION , ATHEROTHROMBOSIS: THE COMPLICATIONS OF THE ATHEROSCLEROTIC PLAQUEEFFECTS OF LIPID LOWERING ON THE ATHEROSCLEROTIC PLAQUE; PERSPECTIVES ON LINKS BETWEEN LIPOPROTEINS AND MECHANISMS OF ATHEROSCLEROSIS; REFERENCES; CHAPTER 6. Genetic Dyslipidemia; INTRODUCTION; COMMON GENETIC DISORDERS OF LIPOPROTEIN METABOLISM; SUMMARY AND CONCLUSIONS; REFERENCES; CHAPTER 7. High-Density Lipoprotein Mutations; HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS IN POPULATIONS; IMPACT OF GENES ON HIGH-DENSITY LIPOPROTEIN CHOLESTEROL; INBORN ERRORS OF HIGH-DENSITY LIPOPROTEIN METABOLISM; REFERENCES , CHAPTER 8. Lipoprotein Oxidation and Modification , English

Additional Edition: ISBN 1-4160-5469-3

Language: English

UID:

Format: 1 online resource (605 p.)

Edition: 1st ed.

ISBN: 1-4377-1123-5

Uniform Title: Braunwald's heart disease.

Content: From basic science to pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options, this new title in the Braunwald's Heart Disease family offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style.

Note: "An Expert Consult title"--Cover. , SECTION I: BASIC MECHANISMS; CHAPTER 1. Human Plasma Lipoprotein Metabolism; THE LIPOPROTEINS; LIPOPROTEIN PROPERTIES; LIPOPROTEIN PRODUCTION; REFERENCES; CHAPTER 2. Regulation and Clearance of Apolipoprotein B-Containing Lipoproteins; INTRODUCTION; APOLIPOPROTEIN B STRUCTURE; APOLIPOPROTEIN B GENE REGULATION AND EDITING , PROTEASOMAL AND NONPROTEASOMAL DEGRADATION OF APOLIPOPROTEIN BASSEMBLY OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; PLASMA METABOLISM OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; EMERGING TARGETS FOR REDUCING PLASMA LEVELS OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; REFERENCES; CHAPTER 3. Absorption and Excretion of Cholesterol and Other Sterols; INTRODUCTION; PHYSICAL-CHEMICAL PROPERTIES AND COMPOSITIONS OF INTESTINAL LIPIDS DERIVED FROM THE DIET AND FROM BILE; SOURCES OF INTESTINAL STEROLS; MOLECULAR PHYSIOLOGY OF INTESTINAL CHOLESTEROL ABSORPTION; FECAL EXCRETION OF INTESTINAL STEROLS , GENETIC ANALYSIS OF INTESTINAL CHOLESTEROL ABSORPTIONFACTORS THAT INFLUENCE INTESTINAL CHOLESTEROL ABSORPTION EFFICIENCY; INHIBITORS OF INTESTINAL CHOLESTEROL ABSORPTION; CONCLUSIONS; REFERENCES; CHAPTER 4. High-Density Lipoprotein Metabolism; INTRODUCTION; HIGH-DENSITY LIPOPROTEINS; CLASSIFICATION OF HIGH-DENSITY LIPOPROTEINS; SYNTHESIS OF HIGH-DENSITY LIPOPROTEIN APOLIPOPROTEIN A-I AND APOLIPOPROTEIN A-II; HIGH-DENSITY LIPOPROTEIN AND CHOLESTEROL EFFLUX; SCHEMATIC OVERVIEW OF HIGH-DENSITY LIPOPROTEIN METABOLISM AND REVERSE CHOLESTEROL METABOLISM; REGULATION OF HEPATIC CHOLESTEROL , REGULATION OF THE PLASMA LEVEL OF HIGH-DENSITY LIPOPROTEINHIGH-DENSITY LIPOPROTEIN METABOLISM; CONCLUSIONS; REFERENCES; CHAPTER 5. Lipoproteins: Mechanisms for Atherogenesis and Progression of Atherothrombotic Disease; INTRODUCTION; INFLAMMATION: A FINAL COMMON PATH THAT LINKS MANY RISK FACTORS TO ATHEROGENESIS; LIPOPROTEINS AND THE INITIATION OF ATHEROSCLEROSIS: RESPONSE TO LOW-DENSITY LIPOPROTEIN RETENTION AND BEYOND; HIGH-DENSITY LIPOPROTEIN: THE ANTIATHEROGENIC LIPOPROTEIN; FATTY STREAK FORMATION; LINKS BETWEEN LIPIDS AND LESION PROGRESSION , ATHEROTHROMBOSIS: THE COMPLICATIONS OF THE ATHEROSCLEROTIC PLAQUEEFFECTS OF LIPID LOWERING ON THE ATHEROSCLEROTIC PLAQUE; PERSPECTIVES ON LINKS BETWEEN LIPOPROTEINS AND MECHANISMS OF ATHEROSCLEROSIS; REFERENCES; CHAPTER 6. Genetic Dyslipidemia; INTRODUCTION; COMMON GENETIC DISORDERS OF LIPOPROTEIN METABOLISM; SUMMARY AND CONCLUSIONS; REFERENCES; CHAPTER 7. High-Density Lipoprotein Mutations; HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS IN POPULATIONS; IMPACT OF GENES ON HIGH-DENSITY LIPOPROTEIN CHOLESTEROL; INBORN ERRORS OF HIGH-DENSITY LIPOPROTEIN METABOLISM; REFERENCES , CHAPTER 8. Lipoprotein Oxidation and Modification , English

Additional Edition: ISBN 1-4160-5469-3

Language: English

UID:

Format: 1 online resource (390 pages) : , color illustrations

Edition: Third edition.

ISBN: 0-323-88286-2 , 0-323-88287-0

Content: Part of the renowned Braunwald family of references, Clinical Lipidology: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on the therapeutic management of patients with high cholesterol levels and other atherogenic lipid disorders. An invaluable resource for cardiologists, lipidologists, endocrinologists, and internal medicine physicians, this one-stop reference covers everything from basic science and the pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options. Now fully updated from cover to cover, the 3rd Edition offers unparalleled coverage of lipidology in an accessible and user-friendly manner.

Note: Preceded by: Clinical lipidology / Christie M. Ballantyne. 2nd ediion. [2015] , Complemented by: Braunwald's heart disease / edited by Leonard S. Lilly. 12th edition. [2023]. , Overview of Lipids and Atherosclerosis -- Overview of Risk Assessment -- Measurement of Low-Density Lipoprotein Cholesterol, Non-High--- Density Lipoprotein Cholesterol, Apolipoprotein B, and Low-Density -- Lipoprotein Particle Concentration -- Triglycerides, Triglyceride-Rich Lipoproteins, and High-Density -- Lipoprotein in Coronary Heart Disease Risk Assessment -- Lipoprotein(a) in Cardiovascular Risk Assessment -- Clinical Evaluation for Genetic Testing and Secondary Causes of -- Dyslipidemia -- Polygenic Risk Scores -- High-Sensitivity C-Reactive Protein -- Emerging Assays for Risk Assessment -- Imaging Atherosclerosis for Risk Stratification : Cardiac Computed -- Tomography and Carotid Ultrasound -- Overview of General Approach to Management of Dyslipidemias -- Treatment Guidelines Overview : American Heart -- Association/American College of Cardiology/Multisociety Guideline and Updates -- Treatment Guidelines Overview : European Society of -- Cardiology/European Atherosclerosis Society Guidelines -- Dietary Patterns for the Prevention and Treatment of Cardiovascular Disease -- Updated Clinical Guide to Exercise and Lipids -- Obesity, Lipids, and Cardiovascular Disease -- Statins -- Cholesterol Absorption Inhibitors -- Omega-3 Fatty Acids -- Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition -- Inclisiran -- Bempedoic Acid -- Pemafibrate : A New Selective Peroxisome Proliferator-Activated -- Receptor-α Modulator for Hypertriglyceridemia Management -- Anti-inflammatory Therapy for Cardiovascular Disease -- Nutraceuticals and Functional Foods for Cholesterol Reduction -- Evolving Therapeutic Targets : Lipoprotein(a) -- Inhibition of ANGPTL3 as a Target for Treating Dyslipidemias -- Evolving Therapeutic Targets : Apolipoprotein C-III -- Evolving Therapeutic Targets : Cholesteryl Ester Transfer Protein Inhibition -- Gene Therapy and Therapeutic Genome Editing in Liver for Lipid Disorders -- Special Patient Populations : Diabetes and Metabolic Syndrome -- Special Patient Populations : Women and Older Adults -- Special Patient Populations : Children and Adolescents -- Special Patient Populations : Familial Hypercholesterolemia and -- Other Severe Hypercholesterolemias -- Special Patient Populations : Treatment of Familial -- Chylomicronemia Syndrome and Sustained Chylomicronemia -- Special Patient Populations : Acute Coronary Syndromes -- Special Patient Populations : Transplant Recipients -- Special Populations : Chronic Kidney Disease -- Special Patient Populations : Lipid Abnormalities in High-Risk -- Racial/Ethnic Groups -- Persons With Human Immunodeficiency Virus.

Language: English

UID:

Format: 1 online resource (390 pages) : , color illustrations

Edition: Third edition.

ISBN: 0-323-88286-2 , 0-323-88287-0

Content: Part of the renowned Braunwald family of references, Clinical Lipidology: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on the therapeutic management of patients with high cholesterol levels and other atherogenic lipid disorders. An invaluable resource for cardiologists, lipidologists, endocrinologists, and internal medicine physicians, this one-stop reference covers everything from basic science and the pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options. Now fully updated from cover to cover, the 3rd Edition offers unparalleled coverage of lipidology in an accessible and user-friendly manner.

Note: Preceded by: Clinical lipidology / Christie M. Ballantyne. 2nd ediion. [2015] , Complemented by: Braunwald's heart disease / edited by Leonard S. Lilly. 12th edition. [2023]. , Overview of Lipids and Atherosclerosis -- Overview of Risk Assessment -- Measurement of Low-Density Lipoprotein Cholesterol, Non-High--- Density Lipoprotein Cholesterol, Apolipoprotein B, and Low-Density -- Lipoprotein Particle Concentration -- Triglycerides, Triglyceride-Rich Lipoproteins, and High-Density -- Lipoprotein in Coronary Heart Disease Risk Assessment -- Lipoprotein(a) in Cardiovascular Risk Assessment -- Clinical Evaluation for Genetic Testing and Secondary Causes of -- Dyslipidemia -- Polygenic Risk Scores -- High-Sensitivity C-Reactive Protein -- Emerging Assays for Risk Assessment -- Imaging Atherosclerosis for Risk Stratification : Cardiac Computed -- Tomography and Carotid Ultrasound -- Overview of General Approach to Management of Dyslipidemias -- Treatment Guidelines Overview : American Heart -- Association/American College of Cardiology/Multisociety Guideline and Updates -- Treatment Guidelines Overview : European Society of -- Cardiology/European Atherosclerosis Society Guidelines -- Dietary Patterns for the Prevention and Treatment of Cardiovascular Disease -- Updated Clinical Guide to Exercise and Lipids -- Obesity, Lipids, and Cardiovascular Disease -- Statins -- Cholesterol Absorption Inhibitors -- Omega-3 Fatty Acids -- Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition -- Inclisiran -- Bempedoic Acid -- Pemafibrate : A New Selective Peroxisome Proliferator-Activated -- Receptor-α Modulator for Hypertriglyceridemia Management -- Anti-inflammatory Therapy for Cardiovascular Disease -- Nutraceuticals and Functional Foods for Cholesterol Reduction -- Evolving Therapeutic Targets : Lipoprotein(a) -- Inhibition of ANGPTL3 as a Target for Treating Dyslipidemias -- Evolving Therapeutic Targets : Apolipoprotein C-III -- Evolving Therapeutic Targets : Cholesteryl Ester Transfer Protein Inhibition -- Gene Therapy and Therapeutic Genome Editing in Liver for Lipid Disorders -- Special Patient Populations : Diabetes and Metabolic Syndrome -- Special Patient Populations : Women and Older Adults -- Special Patient Populations : Children and Adolescents -- Special Patient Populations : Familial Hypercholesterolemia and -- Other Severe Hypercholesterolemias -- Special Patient Populations : Treatment of Familial -- Chylomicronemia Syndrome and Sustained Chylomicronemia -- Special Patient Populations : Acute Coronary Syndromes -- Special Patient Populations : Transplant Recipients -- Special Populations : Chronic Kidney Disease -- Special Patient Populations : Lipid Abnormalities in High-Risk -- Racial/Ethnic Groups -- Persons With Human Immunodeficiency Virus.

Language: English

UID:

Format: xxii, 405 Seiten : , Illustrationen, Diagramme.

Edition: Edition 3

ISBN: 978-0-323-88286-6

Note: Includes bibliographical references and index

Language: English

Subjects: Medicine

Keywords: Lipidstoffwechselstörung ; Aufsatzsammlung

URL: Inhaltsverzeichnis

URL: Klappentext