Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (xii, 206 pages) : , digital, PDF file(s).

Edition: 1st ed.

ISBN: 1-107-23520-0 , 1-107-34155-8 , 1-107-34891-9 , 1-107-35742-X , 1-107-34780-7 , 1-139-06141-0 , 1-107-34530-8 , 1-299-40335-2 , 1-107-34405-0

Content: "This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student, or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research"--Provided by publisher.

Note: Title from publisher's bibliographic system (viewed on 05 Oct 2015). , Cover; Contents; Contributors; Preface; 1 Introducing materiomics; 1.1 Introduction to materiomics; 1.2 The challenge of 'living' materials science; 1.3 Dealing with complexity; 1.4. Emergence of materiomics; 1.5 Conclusion and book outline; Further reading; References; 2 Physico-chemical material properties and analysis techniques relevant in high-throughput biomaterials research; Scope; 2.1 Basic principles: physical and chemical properties of polymeric biomaterials; 2.1.1 Bulk characteristics; Chemical properties; Biodegradation; Thermal properties; Mechanical properties , Static measurementsDynamic measurements; Hardness measurements; 2.1.2 Surface characteristics; Surface chemistry has an important effect on cell behaviour; Surface modifications; Wettability; Topography; 2.2 Relation to materiomics: techniques that allow high-throughput material characterization; 2.2.1 Bulk characterization in high throughput; High-throughput bulk analysis of chemical properties; Fourier transform infrared (FTIR)/Raman spectroscopy; High-throughput bulk analysis of mechanical properties; Nanoindentation; 2.2.2 Surface characterization in high throughput , High-throughput surface analysis of chemical propertiesX-ray photoelectron spectroscopy; Time-of-flight secondary ion mass spectrometry; High-throughput surface analysis of physical properties; Water contact angle; Atomic force microscopy; 2.3 Future perspectives; 2.4 Snapshot summary; Further reading; References; 3 Materiomics using synthetic materials: metals, cements, covalent polymers and supramolecular systems; Scope; 3.1 Introduction; 3.2 Basic principles of different synthetic materials; 3.2.1 Metals and cements; 3.2.2 Synthetic covalent polymers , 3.2.3 Supramolecular chemistry and (bio)materials3.3 Materiomics using synthetic materials; 3.3.1 Screening of metals and cements; 3.3.2 Arrays of synthetic covalent polymers; Variations in monomer composition; Polyacrylates; Tyrosine-derived polymers; Polyesters; Polyurethanes; Polymer blends; Processing of gradients; 3.3.3 Screening of supramolecular biomaterials; Examples of supramolecular systems; Perspective on supramolecular chemistry in materiomics; 3.4 Future perspectives; 3.5 Snapshot summary; Further reading; References; 4 Microfabrication techniques in materiomics; Scope , 4.1 Basic principles of microfabrication4.1.1 Introduction; 4.1.2 Materiomics and μTAS; 4.1.3 Microfabrication techniques and processes; Photolithography; Exposure and post-exposure treatment; Development, descumming and post-baking; Direct writing techniques; Electron beam, focused ion beam and laser-based techniques; Techniques based on atomic force microscopy; Polymer micromoulding techniques; Soft lithography; Hot embossing; Microthermoforming; Micro injection moulding; 4.2 The application of microfabrication in materiomics , 4.2.1 Microfabrication as tool in high-throughput screening of material libraries , English

Additional Edition: ISBN 1-107-01677-0

Language: English

URL: Volltext

URL: https://doi.org/10.1017/CBO9781139061414

UID:

Format: 1 online resource (891 p.)

Edition: Second edition.

ISBN: 0-12-420210-1

Content: Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineeri

Note: Description based upon print version of record. , FrontCover; TissueEngineering; Copyright; Contents; Contributors; Preface; Chapter 1 - Tissue Engineering: An Introduction; REFERENCES; Chapter 2 - Stem Cells; LEARNING OBJECTIVES; 2.1 INTRODUCTION; 2.2 DIFFERENTIATION; 2.3 CHARACTERIZATION OF STEM CELLS: SURFACE PROTEIN EXPRESSION; 2.4 CHARACTERIZATION OF STEM CELLS: GENE EXPRESSION; 2.5 METASTABLE STATES OF STEM CELLS; 2.6 PLURIPOTENT STEM CELLS; 2.7 MULTIPOTENT STEM CELLS; 2.8 STEM CELLS IN SKIN EPITHELIA; 2.9 STEM CELLS IN THE INTESTINE; 2.10 STEM CELLS IN THE CENTRAL NERVOUS SYSTEM; 2.11 FUTURE PERSPECTIVES; 2.12 SUMMARY , RECOMMENDED READINGREFERENCES; Chapter 3 - Tissue Formation during Embryogenesis; LEARNING OBJECTIVES; 3.1 INTRODUCTION; 3.2 CARDIAC DEVELOPMENT; 3.3 BLOOD VESSEL DEVELOPMENT; 3.4 DEVELOPMENT OF PERIPHERAL NERVE TISSUE; 3.5 EMBRYONIC SKIN DEVELOPMENT; 3.6 SKELETAL FORMATION; 3.7 FUTURE DIRECTIONS; 3.8 SUMMARY; Chapter 4 - Cellular Signaling; LEARNING OBJECTIVES; 4.1 GENERAL INTRODUCTION; 4.2 CELLULAR SIGNALING IN SKIN BIOLOGY; 4.3 CELLULAR SIGNALING IN VASCULAR BIOLOGY; 4.4 CELLULAR SIGNALING IN BONE BIOLOGY; 4.5 CELLULAR SIGNALING IN SKELETAL MUSCLE; 4.6 FUTURE DEVELOPMENTS , 4.7 SNAPSHOT SUMMARYRECOMMENDED READING; REFERENCES; Chapter 5 - Extracellular Matrix as a Bioscaffold for Tissue Engineering; LEARNING OBJECTIVES; 5.1 INTRODUCTION; 5.2 NATIVE EXTRACELLULAR MATRIX; 5.3 ECM SCAFFOLD PREPARATION; 5.4 CONSTRUCTIVE TISSUE REMODELING; 5.5 CLINICAL TRANSLATION OF ECM BIOSCAFFOLDS; COMPOSED OF ECM; 5.7 FUTURE CONSIDERATIONS; 5.8 SUMMARY; Chapter 6 - Degradation of Biomaterials; LEARNING OBJECTIVES; 6.1 DEGRADABLE BIOCERAMICS; 6.2 BIODEGRADABLE POLYMERS; 6.3 FUTURE PERSPECTIVES FOR DEGRADABLE BIOMATERIALS IN TISSUE ENGINEERING; 6.4 SUMMARY; REFERENCES , Chapter 7 - Cell-Material InteractionsLEARNING OBJECTIVES; 7.1 INTRODUCTION; 7.2 SURFACE CHEMISTRY; 7.3 SURFACE TOPOGRAPHY; 7.4 MATERIAL MECHANICS (STIFFNESS); 7.5 SUMMARY; REFERENCES; FURTHER READING; Chapter 8 - Materiomics: A Toolkit for Developing New Biomaterials; LEARNING OBJECTIVES; 8.1 INTRODUCTION: WHAT IS MATERIOMICS?; 8.2 WHY DO WE NEED NEW BIOMATERIALS; 8.3 THE SIZE OF CHEMICAL SPACE; 8.4 DESIGN OF EXPERIMENTS/GENETIC EVOLUTION/PARALLELS TO DRUG DISCOVERY; 8.5 HIGH-THROUGHPUT EXPERIMENTAL METHODS; 8.6 COMPUTATIONAL MODELING; 8.7 FUTURE PERSPECTIVE; 8.8 SUMMARY; REFERENCES , Chapter 9 - Microfabrication Technology in Tissue EngineeringLEARNING OBJECTIVES; 9.1 INTRODUCTION; 9.2 MICROFABRICATION TECHNIQUES IN TISSUE ENGINEERING; 9.3 CONCLUSION AND FUTURE PERSPECTIVE; 9.4 SUMMARY; RECOMMENDED READING; REFERENCES; Chapter 10 - Scaffold Design and Fabrication; LEARNING OBJECTIVES; 10.1 INTRODUCTION; 10.2 SCAFFOLD DESIGN; 10.3 CLASSICAL SCAFFOLD FABRICATION TECHNIQUES; 10.4 ELECTROSPINNING; 10.5 ADDITIVE MANUFACTURING; 10.6 CONCLUSION AND FUTURE DIRECTIONS; RECOMMENDED READING; REFERENCES; Chapter 11 - Controlled Release Strategies in Tissue Engineering , LEARNING OBJECTIVES , English

Additional Edition: ISBN 0-12-420145-8

Language: English

Keywords: Electronic books.

URL: Click to View

UID:

Format: 1 online resource (800 pages)

Edition: 3rd ed.

ISBN: 0-323-85134-7 , 9780128244593

Content: Tissue Engineering, Third Edition provides a completely revised release with sections focusing on Fundamentals of Tissue Engineering and Tissue Engineering of Selected Organs and Tissues. Key chapters are updated with the latest discoveries, including coverage of new areas (skeletal TE, ophthalmology TE, immunomodulatory biomaterials and immune systems engineering). The book is written in a scientific language that is easily understood by undergraduate and graduate students in basic biological sciences, bioengineering and basic medical sciences, and researchers interested in learning about this fast-growing field.

Note: Front Cover -- Tissue Engineering -- Tissue EngineeringThird EditionEditorsJan de BoerClemens A. van BlitterswijkAssistant EditorsJorge Alfredo UquillasNusrat Malik -- Contents -- Contributors -- Preface -- 1 - An introduction to tissue engineering -- the topic and the book -- 1.1 Learning objectives -- 1.2 What inspired you to pick up this book? -- 1.3 What is tissue engineering about? -- 1.4 Tissue engineering's origin and progression over time -- 1.5 Tissue engineering's limitations and promises -- 1.6 The future of tissue engineering -- 1.7 Tissue engineering and you -- 1.8 How to use this book? A guide for students and teachers -- 1.9 How to use the chapters? -- 1.10 References -- 2 - Stem cells -- 2.1 Learning objectives -- 2.2 Introduction -- 2.3 What defines a stem cell? Self-renewal, proliferation, and differentiation -- 2.4 Self-renewal -- 2.5 Stem cell proliferation -- 2.6 Stem cell differentiation -- 2.7 Stem cell quiescence and activation -- 2.8 Cell death is normal-apoptosis, autophagy, necrosis, and necroptosis -- 2.9 Characterization of stem cells-protein expression -- 2.10 Characterization of stem cells-RNA analysis by RT-PCR, microarray, and RNA-sequencing -- 2.11 Characterization of stem cells-cell differentiation -- 2.12 Stem cell signaling-the Wnt and β-catenin pathway -- 2.13 Hematopoietic stem cells -- 2.14 Mesenchymal stem cells -- 2.14.1 MSC modulation of the immune system -- 2.14.2 Epithelial stem cells-skin and intestine -- 2.15 Skin stem cells -- 2.16 Lgr5+ stem cells of the intestine -- 2.17 Central nervous system stem cells -- 2.18 Induced pluripotent stem cells-iPS cells -- 2.18.1 Deextinction of the northern white rhino by iPS cells -- 2.19 Natural pluripotent and embryonic stem cells -- 2.19.1 Differentiation of pluripotent stem cells -- 2.19.2 Application of pluripotent stem cells. , 2.20 Organoids, exosomes, and extracts from stem cells -- 2.21 Stem cell mechanobiology: stretch and strain -- 2.22 Future perspective -- 2.23 The dark side: cancer stem cells -- 2.24 Recommended literature -- 2.25 Assessment of your knowledge -- 2.26 Glossary -- 2.27 Further reading -- 3 - Tissue formation during embryogenesis -- 3.1 Learning objectives -- 3.2 Introduction -- 3.2.1 Organ formation during embryogenesis -- 3.2.2 The formation of the three germ layers during gastrulation -- 3.2.3 Establishment of the body plan by morphogen signaling -- 3.2.4 Neural crest cells -- 3.3 Cardiac development -- 3.3.1 Geometrical changes transform a single beating heart tube into a four-chambered heart -- 3.3.2 Cardiomyocytes -- 3.3.3 Future perspective -- 3.4 Blood vessel development -- 3.4.1 Vasculogenesis and angiogenesis -- 3.4.2 Blood pressure drives specification of vessels in arteria or veins -- 3.4.3 Vessel wall stabilization by smooth muscle cells and pericytes -- 3.4.4 Recruitment of mural cells is mediated by PDGF signaling -- 3.4.5 Future perspective -- 3.5 Development of peripheral nerve tissue -- 3.5.1 Development of the schwann cell lineage -- 3.5.2 Myelinating and nonmyelinating nerve fibers -- 3.5.3 Structure of the peripheral nerve sheath -- 3.5.4 Future perspective -- 3.6 Embryonic skin development -- 3.6.1 Interfollicular epidermis -- 3.6.2 Follicular epidermis -- 3.6.3 Dermis -- 3.6.4 Tissue engineering of embryonic and newborn skin -- 3.6.5 Cell-cell interactions and growth factors -- 3.6.6 Future perspective -- 3.7 Bone development -- 3.7.1 Skeletal precursor cells -- 3.7.2 Endochondral ossification -- 3.7.3 Intramembranous ossification and osteoblast differentiation -- 3.7.4 Osteoclast differentiation -- 3.7.5 Tissue engineering of bone -- 3.7.6 Tissue engineering of articular cartilage -- 3.7.7 Future perspective. , 3.8 Recommended literature -- 3.9 Assessment of your knowledge -- 3.10 Glossary -- 4 - Cellular signaling -- 4.1 Learning objectives -- 4.2 Paradigm of cellular signaling -- 4.3 Signal initiation -- 4.4 Signal transduction -- 4.4.1 G-protein-coupled receptor-mediated signaling -- 4.4.2 Receptor tyrosine kinase signaling -- 4.4.3 TGF-β superfamily signaling -- 4.4.4 Wnt signaling -- 4.4.5 Rho kinase signaling -- 4.4.6 NF-κB signaling -- 4.4.7 Vitamin D signaling -- 4.5 Gene activation -- 4.6 Variations on a theme -- 4.7 Future perspective -- 4.8 Recommended literature -- 4.9 Assessment of your knowledge -- 4.10 Glossary -- 4.11 References -- 5 - Extracellular matrix as a bioscaffold for tissue engineering -- 5.1 Learning objectives -- 5.2 Introduction -- 5.3 Native extracellular matrix -- 5.3.1 ECM composition -- Collagen -- Fibronectin -- Laminin -- Glycosaminoglycans -- Growth factors -- 5.4 ECM scaffold preparation -- 5.5 Constructive tissue remodeling -- 5.5.1 Default mammalian wound healing versus constructive remodeling -- 5.5.2 Mechanisms behind ECM-mediated constructive tissue remodeling -- Scaffold degradation -- Endogenous cell therapy by ECM bioscaffolds -- Modulation of the host immune response by ECM bioscaffolds -- Macrophage heterogeneity -- ECM bioscaffolds promote a constructive macrophage phenotype -- Antimicrobial properties of ECM bioscaffolds -- 5.6 Clinical translation of ECM bioscaffolds -- 5.6.1 Skeletal muscle reconstruction -- 5.6.2 Esophageal mucosa reconstruction -- 5.7 Commercially available scaffolds composed of ECM -- 5.8 Future perspective -- 5.9 Recommended literature -- 5.10 Assessment of your knowledge -- 5.11 Glossary -- 5.12 References -- 6 - Synthetic biomaterials -- 6.1 Learning objectives -- 6.2 Introduction -- 6.2.1 Why are biomaterials important? -- 6.2.2 Synthetic biomaterials and their features. , 6.3 Biomaterials and synthetic chemistry: a molecular view -- 6.3.1 Atoms, molecules, and interactions -- 6.3.2 Classes of materials -- Polymers: naturals, synthetics, and hybrids -- Inorganics: ceramics and glasses -- Composites -- 6.3.3 Synthetic transformations -- 6.4 The extracellular matrix: a chemical view -- 6.4.1 What are we trying to mimic? -- 6.4.2 The ECM is nothing but polymers and composites -- 6.5 Rational design -- 6.5.1 Degradation -- 6.5.2 Mechanical properties -- 6.5.3 Stimuli response -- 6.5.4 Bioactivity -- 6.5.5 Biomimicry -- 6.6 Future developments -- 6.6.1 Spatiotemporal complexity -- 6.6.2 Biohybrid approaches -- 6.6.3 Rational design -- 6.6.4 Precision -- 6.7 Case study: vascularization -- 6.7.1 How to create a synthetic system for vascularization -- 6.7.2 Designing a material system -- Clinical/industrial solution -- Academic solution -- Testing -- 6.8 Recommended literature -- 6.8 Recommended literature -- 6.9 Assessment of your knowledge -- 6.10 Glossary -- 6.11 References -- 7 - Degradation of biomaterials -- 7.1 Learning objectives -- 7.2 Introduction -- 7.3 Bioceramics and glasses -- 7.3.1 Properties of bioceramics and glasses that influence degradation -- 7.3.2 Degradation mechanisms of bioceramics -- Physicochemical degradation of bioceramics -- Cellular degradation of bioceramics -- 7.4 Biodegradable polymers -- 7.4.1 Introduction -- 7.4.2 Mechanisms of polymer degradation and erosion -- 7.4.3 Bulk erosion -- Overview -- Surface erosion -- Degradation kinetics -- 7.4.4 Factors that influence degradation -- 7.4.5 Material composition -- 7.4.6 Bulk eroding polymers -- 7.4.7 Surface-eroding polymers -- 7.4.8 Molecular weight -- 7.4.9 Crystallinity -- 7.4.10 Glass transition temperature -- 7.4.11 Architecture -- 7.4.12 Processing -- 7.4.13 In vivo degradation -- Conditions at implantation site -- Inflammatory response. , Size and shape -- 7.4.14 In vitro testing and characterization -- 7.4.15 In vivo testing and characterization -- 7.5 Biodegradable metals -- 7.5.1 Principles of metal corrosion -- Corrosion in the in vivo environment -- Localized corrosion effects -- 7.5.2 Magnesium-based implants -- Magnesium corrosion -- Controlling magnesium degradation rates -- Mg-based tissue scaffolds: designing for function and enhanced properties -- 7.6 Future perspective -- 7.7 Recommended literature -- 7.8 Assessment of your knowledge -- 7.9 Glossary -- 7.10 References -- 8 - Cell-material interactions -- 8.1 Learning objectives -- 8.2 Introduction -- 8.2.1 Cell-material/cell-extracellular matrix interactions -- 8.2.2 Integrins -- 8.2.3 Integrin-mediated adhesion structures -- 8.2.4 Mechanotransduction -- 8.2.5 Cell adherence to synthetic materials -- 8.3 Surface chemistry -- 8.3.1 Hydrophobicity and hydrophilicity -- 8.3.2 Presentation of chemical groups -- 8.3.3 Patterning using surface chemistry -- 8.3.4 Ligand spacing -- 8.3.5 Dynamic chemistry -- 8.4 Material mechanics (stiffness) -- 8.4.1 Cell behaviors and matrix mechanics -- 8.4.2 Mimicking tissue stiffness in vitro -- 8.4.3 Stem cell differentiation and substrate mechanics -- 8.5 Topography -- 8.5.1 Cell guidance by micro- and nanostructures -- 8.5.2 Nanotopography and stem cell differentiation -- 8.6 Future perspective -- 8.7 Recommended literature -- 8.8 Assessment of your knowledge -- 8.9 Glossary -- 8.10 References -- 9 - Biomaterials discovery: experimental and computational approaches -- 9.1 Learning objectives -- 9.2 Introduction -- 9.3 The challenges of biomaterials discovery -- 9.4 Approaches to materials discovery -- 9.5 Experimental high throughput materials discovery -- 9.5.1 The supporting substrate and coating -- 9.5.2 Materials libraries -- 9.5.2.1 High throughput screening systems. , 9.5.2.2 Combinatorial polymer libraries.

Additional Edition: Print version: Blitterswijk, Clemens Van Tissue Engineering San Diego : Elsevier Science & Technology,c2022

Language: English

UID:

Format: 152, [81] S. , Ill., zahlr. graph. Darst.

ISBN: 3816767370

Note: Zugl.: Stuttgart, Univ., Diss., 2004

Language: German

Subjects: Engineering

Keywords: Hochschulschrift

URL: Inhaltsverzeichnis

URL: http://sebi-images.zlb.de/inhaltsverzeichnisse/000513685.pdf

Author information: Boer, Jan de 1968-

UID:

Format: 150 S. 8"

Note: Groningen, Diss., 1984

Language: Undetermined

UID:

Format: VIII S., S. 345-372. 8"

Note: Aus: Acta physiologica et pharmacologica Neerlandica. 12. 1963 , Leiden, Diss

Language: Undetermined

UID:

Format: Ill.

ISBN: 978-3-927787-43-4

In: pages:42-43

In: Festschrift 1912-2012, Berlin, 2012, S. 42-43, 978-3-927787-43-4

Language: German

UID:

Format: XXVI, 202 S

ISBN: 9050954669

Note: Books 2, 3, 4, 5, 6, and 7 are already transl. and available in the following publ.: Kluwer Law International Series of legislation in translation: No. 17 and No. 19

Language: English

UID:

Format: XII, 161 S , 8"

Language: Undetermined

UID:

Format: XI, 212 S. , zahlr. Ill., graph. Darst.

Edition: 2. dr., Nachdr. der Ausg. 1948

ISBN: 906378015X

Language: Dutch