UID:
almafu_9959328952002883
Format:
1 online resource (xviii, 307 pages) :
,
illustrations
Edition:
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
ISBN:
9783527613090
,
3527613099
,
9783527613083
,
3527613080
,
1282010352
,
9781282010352
Series Statement:
Methods and principles in medicinal chemistry ; v. 10
Content:
Recent progress in high-throughput screening, combinatorial chemistry and molecular biology has radically changed the approach to drug discovery in the pharmaceutical industry. New challenges in synthesis result in new analytical methods. At present, typically 100,000 to one million molecules have to be tested within a short period and, therefore, highly effective screening methods are necessary for today's researchers - preparing and characterizing one compound after another belongs to the past. Intelligent, computer-based search agents are needed and "virtual screening" provides so.
Note:
High-throughput screening and virtual screening: entry points to drug discovery /
,
Library filtering systems and prediction of drug-like properties /
,
Prediction of physicochemical properties /
,
Descriptor-based similarity measures for screening chemical databases /
,
Modelling structure-activity relationships /
,
Database profiling by neural networks /
,
Pharmacophore pattern application in virtual screening, library design and QSAR /
,
Evolutionary molecular design in virtual fitness landscapes /
,
Practical approaches to evolutionary design /
,
Understanding receptor-ligand interactions as a prerequisite for virtual screening /
,
Structure-based library design /
,
The measurement of molecular diversity /
,
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Additional Edition:
Print version: Virtual screening for bioactive molecules. Weinheim ; New York : Wiley-VCH, ©2000 ISBN 9783527301539
Additional Edition:
ISBN 3527301534
Language:
English
Subjects:
Chemistry/Pharmacy
Keywords:
Electronic books.
DOI:
10.1002/9783527613083
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527613083
Bookmarklink
