Kooperativer Bibliotheksverbund

UID:

Format: 1 Online-Ressource (XXXIX, 453 p. 140 illus., 71 illus. in color)

ISBN: 9783319388106

Series Statement: Advances in Experimental Medicine and Biology 923

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-38808-3

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-38809-0

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-81752-1

Language: English

DOI: 10.1007/978-3-319-38810-6

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 online resource (554 p.)

Edition: 1st ed. 2010.

ISBN: 1-282-83136-4 , 9786612831362 , 1-4419-1241-X

Series Statement: Advances in experimental medicine and biology, 662

Content: This book covers all aspects involved in uptake of oxygen from the air, transport by blood stream, and its ultimate consumption in the cell in various organs as discussed at the 36th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) held in Sapporo, Japan in August 2008. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biomedical engineering, physiology, biochemistry, molecular biology, and clinical medicine.

Note: Selected conference papers from the annual meeting of the International Society on Oxygen Transport to Tissue, held in Sapporo, Japan during August 3-7, 2008--preface. , Oxygen Transport to Tissue XXXI; Advances in Experimental Medicine and Biology; International Society on Oxygen Transport to Tissue (ISOTT); ISOTT2008; Oxygen Transport to Tissue XXXI; Preface; Contents; Contributors; Part 1: Physiology and Pathophysiology of O2 Transport; Unfinished Physiology; 1 Introduction; References; Cell Respiration Under Hypoxia: Facts and Artefacts in Mitochondrial Oxygen Kinetics; 1 Introduction; 2 Mitochondrial and Cellular Oxygen Kinetics; 2.1 Isolated Mitochondria; 2.2 Intact Cells; 3 Oxygen Kinetics and High-Resolution Respirometry , 3.1 Nanomolar Resolution of Oxygen Concentration3.2 High-Resolution Oxygen Kinetics: Effects of Cell Density and Cell Activity; 4 Discussion; 4.1 Comparative Mitochondrial Physiology and p50 of Mitochondrial Respiration; 4.2 Methodological Limitations of Closed Systems; 4.3 Variation of p50 in Open Systems; 4.4 Variation of p50 In Vivo; 5 Conclusions; References; Alveolar Hypoxia-Induced Systemic Inflammation: What Low PO2 Does and Does Not Do; 1 Introduction; 2 Dissociation Between Cremaster Microvascular PO2 Values and Cremaster Inflammation , 3 Plasma from Hypoxic Rats Produces Inflammation in Normoxic Cremaster4 Alveolar Macrophages Are Necessary for the Inflammation of Alveolar Hypoxia; 5 Activation of Mast Cells by the AMÄ-Generated Intermediary Stimulates the Local Renin-Angiotensin System (RAS); References; The Influence of Oxygen Supply, Hemorheology and Microcirculation in the Heart and Vascular Systems; 1 Microcirculation Anatomy; 2 Endothelial Physiology; 3 Hemorheology and the Microcirculation; 4 Vessels and Oxidative Stress; 5 Microcirculation and the Heart; 6 Microcirculation and Pathology; References , Could Dilated Cardiomyopathy Alter the Peripheral Microcirculation and Blood Rheology?1 Introduction; 2 Material and Methods; 3 Results; 4 Discussion; 5 Conclusion; References; The Role of Glyoxalase System in Renal Hypoxia; 1 Hypoxia in the Kidney; 2 Role of Methylglyoxal (MG), a Precursor of Protein Glycation, in Hypoxic Injury; 3 Glyoxalase System for Detoxification of MG and its Pathophysiology; 4 Renoprotective Effect of Glyoxalase I in Hypoxic Injury; 5 Conclusion; References; Intracortical Microcirculatory Change Induced by Anesthesia in Rat Somatosensory Cortex; 1 Introduction , 2 Materials and Methods3 Results; 4 Discussion; References; Macrophages That Survive Hyperoxia Exposure Have Higher Superoxide Dismutase Activities in Their Mitochondria; 1 Introduction; 2 Materials and Methods; 2.1 Macrophages Culture; 2.2 Cell Counting and SOD Activity Assay; 2.3 Isolation and Amplification of DNA; 2.4 Sequence Analysis of Mitochondrial DNA; 2.5 PCR-RFLP Assay; 2.6 Statistical Analysis; 3 Results; 4 Discussion; References; Diet-Induced Ketosis Improves Cognitive Performance in Aged Rats; 1 Introduction; 2 Methods and Materials; 2.1 Animal Preparation and Hypoxic Exposure , 2.2 Behavioral Tests , English

Additional Edition: ISBN 1-4614-2538-7

Additional Edition: ISBN 1-4419-1239-8

Language: English

DOI: 10.1007/978-1-4419-1241-1

UID:

ISBN: 0306427958

Series Statement: Advances in experimental medicine and biology 222

In: 10

Language: English

UID:

Format: XII, 211 S , Ill., graph. Darst

ISBN: 0943255147

Series Statement: Advances in applied biotechnology series 11

Language: Undetermined

UID:

Format: XXVII S., S. 637 - 1161 , Ill., graph. Darst

ISBN: 0306390949

Series Statement: Oxygen transport to tissue [1],2

Language: English

UID:

Format: Online-Ressource (XXX, 372 p.) , Ill.

Edition: Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences

ISBN: 9781493906208

Series Statement: Advances in Experimental Medicine and Biology 812

Content: This book contains the refereed contributions from the 41st annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. Traditionally, ISOTT conferences are a place, where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The papers in this volume summarize some of the outstanding contributions from the 41st annual meeting. Special features in this volume include invited presentations from senior members of ISOTT for the theme “the wisdom of ISOTT” in which founders, past presidents and prize winners from previous meetings provided both cutting edge new knowledge and integrated overviews of critical aspects of the field. The presentations and manuscripts also include those provided by the special opportunity provided by having part of the ISOTT meeting overlap with the EPR-2013 meeting where both focused on preclinical and clinical measurements of oxygen, with a particular emphasis on cancer

Note: Description based upon print version of record , Dedication; Preface; Acknowledgements; Panel of Reviewers; Local Organizing Committee: The Geisel School of Medicine at Dartmouth; Scientific Advisory Committee; ISOTT Officers and Executive Committee; ISOTT Award Winners; The Melvin H. Knisely Award; Melvin H. Knisely Award Recipients; The Dietrich W. Lübbers Award; Dietrich W. Lübbers Award Recipients; The Britton Chance Award; Britton Chance Award Recipients; The Duane F. Bruley Travel Awards; Duane F. Bruley Award Recipients; Kovach Lecture; Kovach Lecture Recipients; Contents , Chapter 1: Mitochondrial Genetic Abnormalities After Radiation Exposure1 Introduction; 2 Methods; 3 Results; 4 Discussion; 5 Conclusion; References; Chapter 2: Crediting Six Discoverers of Oxygen; Chapter 3: Hypoxia in Tumors: Pathogenesis-Related Classification, Characterization of Hypoxia Subtypes, and Associated Biological and Clinical Implications; 1 Introduction; 2 Chronic Hypoxia; 3 Acute Hypoxia; 4 Hypoxia-Associated Biological and Clinical Implications; 5 Conclusions; References , Chapter 4: Heterogeneity in Tissue Oxygenation: From Physiological Variability in Normal Tissues to Pathophysiological Chaos in Malignant Tumours1 Heterogeneity of Blood Flow; 2 Heterogeneity of Oxygen Supply: The Tissue pO 2 Histogram; 3 Physiological Response of Tissue O 2 Supply; 4 Pathological Responses of Tissue O 2 Supply in Normal Microvasculature and in Malignant Tumours; 5 Conclusions; References; Chapter 5: Oxygen Diffusion: An Enzyme-Controlled Variable Parameter; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; 5 Conclusion; References , Chapter 6: Role of Microvascular Shunts in the Loss of Cerebral Blood Flow Autoregulation1 Introduction; 2 Methods; 2.1 Two Photon Laser Scanning Microscopy Studies; 2.1.1 Microvascular Shunting by Increasing Intracranial Pressure; 2.1.2 Increasing CPP Attenuates the Transition from Capillary Flow to Microvascular Shunts with Increasing ICP; 2.2 Multimodal Monitoring System in Patients; 3 Results; 4 Discussion; 5 Conclusions; References; Chapter 7: Impact of Hypoxia-Related Tumor Acidosis on Cytotoxicity of Different Chemotherapeutic Drugs In Vitro and In Vivo; 1 Introduction , 2 Material and Methods2.1 Cell Lines; 2.2 Chemotherapy; 2.3 Forcing Glycolytic Metabolism; 2.4 Measurement of Apoptosis Induction and Cell Survival; 3 Results; 4 Discussion; References; Chapter 8: The Founding of ISOTT: The Shamattawa of Engineering Science and Medical Science; 1 The Merging of Engineering and Medical Sciences; References; Chapter 9: A Tale of Two Methods: Combining Near-­Infrared Spectroscopy with MRI for Studies of Brain Oxygenation and Metabolism; 1 Introduction; 2 Fiber Optics and MRI, the Issues and Solutions to Multimodality Imaging , 3 Advantages of Combining NIRS and MRI , Mitochondrial Genetic Abnormalities after Radiation ExposureCrediting Six Discoverers of Oxygen -- Hypoxia in Tumors: Pathogenesis-related Classification, Characterization of Hypoxia subtypes, and Associated Biological and Clinical Implications -- Heterogeneity in Tissue Oxygenation: From Physiological Variability in Normal Tissues to Pathophysiological Chaos in Malignant Tumours -- Oxygen Diffusion: An Enzyme-controlled Variable Parameter -- Role of Microvascular Shunts in the Loss of Cerebral Blood Flow Autoregulation -- Impact of Hypoxia-related Tumor Acidosis on Cytotoxicity of Different Chemotherapeutic Drugs in vitro and in vivo -- The Founding of ISOTT: The Shamattawa of Engineering Science and Medical Science -- A Tale of Two Methods: Combining Near-Infrared Spectroscopy with MRI for Studies of Brain Oxygenation and Metabolism -- Advances in Probes and Methods for Clinical EPR Oximetry -- Real-Time, In Vivo Determination of Dynamic Changes in Lung and Heart Tissue Oxygenation using EPR Oximetry -- Modulation of Hypoxia by Magnetic Nanoparticle Hyperthermia to Augment Therapeutic Index -- Skeletal Muscle and Glioma Oxygenation by Carbogen Inhalation in Rats: A Longitudinal Study by EPR Oximetry using Single-Probe Implantable Oxygen Sensors -- Recurrent Low-dose Chemotherapy to Inhibit and Oxygenate Head and Neck Tumors -- How in vivo EPR Measures and Images Oxygen -- What We Learn From In Vivo EPR Oxygen Images -- EPR Image Based Oxygen Movies for Transient Hypoxia -- Repetitive Measurements of Intrarenal Oxygenation in vivo using L band Electron Paramagnetic Resonance -- Quantitative Hypoxia Imaging for Treatment Planning of Radiotherapy -- A New Flavonoid Regulates Angiogenesis and Reactive Oxygen Species Production -- Angiotensin II Reduces Transport-Dependent Oxygen Consumption but Increases Transport-Independent Oxygen Consumption in Immortalized Mouse Proximal Tubular Cells -- Investigation of Cerebral Autoregulation in the Newborn Piglet during Anaesthesia and Surgery -- Influence of the Maternal use of Labetalol on the Neurogenic Mechanism for Cerebral Autoregulation Assessed by Means of NIRS -- Development of a Near Infrared Multi-Wavelength, Multi-channel, Time-Resolved Spectrometer for Measuring Brain Tissue Haemodynamics and Metabolism -- Simulating NIRS and MRS measurements during cerebral hypoxia-ischaemia in piglets using a computational model -- Analysis of Slow Wave Oscillations in Cerebral Haemodynamics and Metabolism Following Subarachnoid Haemorrhage -- Effects of Enriched Environment on Hippocampal Neuronal Cell Death and Neurogenesis in Rat Global Ischemia -- Automated Image Analysis for Diameters and Branching Points of Cerebral Penetrating Arteries and Veins Captured with Two-Photon Microscopy -- Cerebral Hemodynamic Changes and Metabolic Alteration in Severe Hemorrhagic Shock -- Physiological Mechanism of Increase in Deoxy-hemoglobin Concentration during Neuronal Activation in Patients with Cerebral Ischemia: A Simulation Study with the Balloon Model -- Effect of Blood in the Cerebrospinal Fluid on the Accuracy of Cerebral Oxygenation Measured by Near Infrared Spectroscopy -- Vessel Specific Imaging of Glucose Transfer with Fluorescent Glucose Analogue in Anesthetized Mouse Cortex -- Ischemic Pretreatment Delays Ischemic Brain Vasospasm Injury in Gerbils -- Changes in Cerebral Blood Oxygenation Induced by Active Standing Test in Children with POTS and NMS -- Optical Imaging of Brain Activation in Gambian Infants -- Asymmetrical Changes in Cerebral Blood Oxygenation Induced by an Active Standing Test in Children with Postural Tachycardia Syndrome -- Changes of Cerebral Tissue Oxygen Saturation at Sleep Transitions in Adolescents -- Influence of Subjective Happiness on the Prefrontal Brain Activity: An fNIRS Study -- Ginkobiloba Extract Improves Working Memory Performance in Middle-aged women; Role of Asymmetry of Prefrontal Cortex Activity during a Working Memory Task -- Bayesian Prediction of Anxiety Level in Aged People at Rest using 2-Channel NIRS Data from Prefrontal Cortex -- Short-term Hypoxic Preconditioning Improved Survival following Cardiac Arrest and Resuscitation in rats -- Venular Valves and Retrograde Perfusion -- Monitoring of Filter Patency during Carotid Artery Stenting using Near-Infrared Spectroscopy with High Time-Resolution -- Use of NIRS to Assess Effect of Training on Peripheral Muscle Oxygenation Changes in Elite Rugby Players Performing Repeated Supramaximal Cycling Tests -- Skeletal Muscle Deoxygenation Responses during Treadmill Exercise in Children -- Development of a Hybrid Microwave-Optical Thermoregulation Monitor for the Muscle -- Evaluation of a Textile-Based Near Infrared Spectroscopy System in Calf Muscle Oxygenation Measurements -- Skin Temperature in Lower Hind Limb Subjected to Distal Vein Arterialization in Rats -- Index.

Additional Edition: ISBN 9781493905836

Additional Edition: Print version Oxygen Transport to Tissue XXXVI

Language: English

Subjects: Biology

Keywords: Sauerstoffversorgung

DOI: 10.1007/978-1-4939-0620-8

URL: Volltext  (lizenzpflichtig)

URL: Volltext

UID:

Format: XVI, 338 p. 114 illus., 6 illus. in color. , online resource.

Edition: 1st ed. 2009.

ISBN: 9780387859989

Series Statement: Advances in Experimental Medicine and Biology, 645

Content: In 1772 in Uppsala the Swedish chemist Karl Wilhelm Scheele discovered the element Oxygen. Two hundred and one years later, in 1973, the International Society on Oxygen Transport to Tissue (ISOTT) was founded. Since then there has been an annual ISOTT meeting. After 24 years of international ISOTT meetings it was decided, at the 2005 summit in Bary, Italy, that the 2007 meeting was to be held in Uppsala, Sweden. Thus, after the Louisville meeting we, in the Uppsala group, withdrew to the Edgewater Resort at Taylorsville Lake outside Louisville and prepared the Uppsala ISOTT meeting by tasting Kentucky Bourbons, smoking cigars while bathing in a jacuzzi in the hot dark Kentucky night full of fire flies and a sky full of stars. The ISOTT program should include different aspects of oxygen - however, it is accepted that each meeting has its own local "touch". We decided to focus the Uppsala ISOTT meeting on the theme of "Imaging and measuring oxygen changes". With this in mind we invited scientists within and outside the ISOTT society. We then also received lots of good abstracts from ISOTT members that were included in the program. Lars-Olof Sundelöf introduction speech "AIR AND FIRE" concerned how oxygen was discovered in Uppsala in 1772 by Karl Wilhelm Scheele. After the introduction speech a get together event took place in the magnificent and spacious foyer of Uppsala University main building. The vice chancellor Ulf Pettersson welcomed all delegates to Sweden and Uppsala.

Note: Air And Fire -- Mathematical Modeling of The Interaction Between Oxygen, Nitric Oxide And Superoxide -- Haemoglobin Saturation Controls The Red Blood Cell Mediated Hypoxic Vasorelaxation -- Blood Vessel Specific Vaso-Activity To Nitrite Under Normoxic And Hypoxic Conditions -- Nitrite-Induced Improved Blood Circulation Associated With An Increase In A Pool Of Rbc-No With No Bioactivity -- The Control of Oxidative Phosphorylation in the Adrenal Gland (Y1) Cell Line -- Replication of Murine Mitochondrial DNA Following Irradiation -- Effects of Anesthesia on Brain Mitochondrial Function, Blood Flow, Ionic And Electrical Activity Monitored in Vivo -- The Influence Of Flow Redistribution On Working Rat Muscle Oxygenation -- Heterogeneity Of Capillary Spacing In The Hypertrophied Plantaris Muscle From Young-Adult And Old Rats -- Microvascularity of the Lumbar Erector Spinae Muscle During Sustained Prone Trunk Extension Test -- Fiber Capillary Supply Related To Fiber Size And Oxidative Capacity In Human And Rat Skeletal Muscle -- Novel Therapeutic Approach Targeting The Hif-Hre System In The Kidney -- Carotid Body Sensory Discharge And Glomus Cell Hif-1? Are Regulated By A Common Oxygen Sensor -- Impact of Reactive Oxygen Species on the Expression of Adhesion Molecules in Vivo -- Mini Sensing Chip for Point-of-Care Acute Myocardial Infarction Diagnosis Utilizing Micro-Electro-Mechanical System and Nano-Technology -- A Chemical Biosynthesis Design for an Antiatherosclerosis Drug by Acyclic Tocopherol Intermediate Analogue Based on "Isoprenomics" -- Zymogen Protein C Concentrate for Safer Heterozygote Surgery, "I am a Guinea Pig!" -- Steady State Redox Levels in Cytochrome Oxidase: Relevance for in Vivo Near Infrared Spectroscopy (Nirs) -- Bicuculline-Induced Seizures: A Challenge for Optical and Biochemical Modeling of the Cytochrome Oxidase CuA Nirs Signal -- A Method to Calculate Arterial and Venous Saturation from Near Infrared Spectroscopy (Nirs) -- Development Of A Dynamic Test Phantom For Optical Topography -- Numerical Simulation Of Oxygen Transport In Cerebral Tissue -- Non-Invasive Estimation Of Metabolic Flux And Blood Flow In Working Muscle: Effect Of Blood-Tissue Distribution -- Oxygen Extraction Index Measured By Near Infrared Spectroscopy - A Parameter For Monitoring Tissue Oxygenation? -- Non-Invasive Measurement Of the Superficial Cortical Oxygen Partial Pressure -- One Sensor Fits All - A New Approach In Monitoring Brain Physiology -- Evaluation Of Nirs Data Based On Theoretical Analysis Of Oxygen Transport to Cerebral Tissue -- Myocardial Capillary Net And Blood Constituents In Streptozotocin (Stz)-Induced Diabetic Rats -- Effects Of Proinsulin C-Peptide On Oxygen Transport, Uptake and Utilization In Insulinopenic Diabetic Subjects - A Review -- Reduced Oxygenation In Diabetic Rat Kidneys Measured By T2* Weighted Magnetic Resonance Micro-Imaging -- Identification and Distribution of Uncoupling Protein Isoforms in the Normal and Diabetic Rat Kidney -- Iodinated Contrast Media Decrease Renomedullary Blood Flow -- C-Peptide Normalizes Glomerular Filtration Rate in Hyperfiltrating Conscious Diabetic Rats -- Lipoprotein Nanoplatform for Targeted Delivery of Diagnostic and Therapeutic Agents -- Prognostic Potential Of The Pretherapeutic Tumor Oxygenation Status -- Histological Basis Of Mr/Optical Imaging Of Human Melanoma Mouse Xenografts Spanning A Range Of Metastatic Potentials -- The Relationship Between Vascular Oxygen Distribution And Tissue Oxygenation -- Intraoperative Measurement Of Colonic Oxygenation During Bowel Resection -- Quantifying Tumour Hypoxia By Pet Imaging - A Theoretical Analysis -- New Measurements For Assessment Of Impaired Cerebral Autoregulation Using Near-Infrared Spectroscopy -- Single Shot T1? Magnetic Resonance Imaging Of Metabolically Generated Water In Vivo -- Brain Tissue Oxygen Consumption And Supply Induced By Neural Activation: -- Brain Oxygen Balance Under Various Experimental Pathophysiologycal Conditions -- Ketones Suppress Brain Glucose Consumption -- False Positives In Functional Nearinfrared Topography -- Relationship Between Brain Tissue Haemodynamics, Oxygenation And Metabolism In The Healthy Human Adult Brain During Hyperoxia And Hypercapnea -- Use Of A Codman® Microsensor Intracranial Pressure Probe: Effects On Near Infrared Spectroscopy Measurements And Cerebral Hemodynamics In Rats -- Effect of Severe Hypoxia on Prefrontal Cortex and Muscle Oxygenation Responses at Rest and During Exhaustive Exercise.

In: Springer Nature eBook

Additional Edition: Printed edition: ISBN 9780387874135

Additional Edition: Printed edition: ISBN 9781441946799

Additional Edition: Printed edition: ISBN 9780387859972

Language: English

DOI: 10.1007/978-0-387-85998-9

URL: https://doi.org/10.1007/978-0-387-85998-9

UID:

Format: XXIV, 410 p. 123 illus., 5 illus. in color. , online resource.

Edition: 1st ed. 2008.

ISBN: 9780387749112

Series Statement: Advances in Experimental Medicine and Biology, 614

Content: The 34th Annual Conference of the International Society on Oxygen Transport to Tissue (ISOTT) was held during August 12-17, 2006 in Louisville, Kentucky, USA. The emphasis of ISOTT-2006 was on ''Expanding our Horizon. '' In terms of research topics, we added some newer ones - Translational Studies, Tissue Engineering, and Nanobiotechnology. In terms of participants, we put extra effort into including more junior researchers because we felt that they were the future of our society and for the first time in ISOTT history we had presentations made by high school students. In terms of organization, it was truly local, national, and international. The support in organizing ISOTT-2006 came from various directions: We would like to express our special thanks to the University of Louisville (UofL), especially to the UofL Provost Office, Speed School of Engineering, School of Medicine, and the office of the Vice President of Research. UofL's financial support allowed us to supplement the student's registration fees s- stantially and to invite so many excellent distinguished lecturers. It should be noted that none of our invited speakers requested an honorarium - we thank them immensely. I would personally like to thank the Chemical Engineering Department of UofL for allowing me to take time off from my teaching resp- sibility. We appreciate UofL President Ramsey's visit to our dinner held at the Derby Museum. We thank the Case Western Reserve University for having their MIMS Center symposium with us.

Note: ISOTT: Roots, Founding and Beyond -- ISOTT: Roots, Founding and Beyond -- Dietrich W. Lübbers -- Oxygen Transport in Tissue -- Investigation of Frontal Cortex, Motor Cortex and Systemic Haemodynamic Changes During Anagram Solving -- Do Red Blood Cell-?-Amyloid Interactions Alter Oxygen Delivery in Alzheimer's Disease? -- Uncoupling Protein-2 in Diabetic Kidneys -- Measurement of Oxygenation at the Site of Stem Cell Therapy in a Murine Model of Myocardial Infarction -- Oxygen Pressures in the Interstitial Space of Skeletal Muscle and Tumors in vivo -- Other Metabolite Transport in Tissue -- Adjuvant Induced Glucose Uptake by Activated T Cells is not Correlated with Increased Survival -- Lactate, with Oxygen, Incites Angiogenesis -- Blood, Hemostasis and Hemodynamics -- Activated Protein C Modulates Chemokine Response and Tissue Injury in Experimental Sepsis -- Manipulation of the Affinity Between Protein and Metal Ions by Imidazole and PHfor Metal Affinity Purification of Protein c from Cohn Fraction IV-1 -- Separation of Factor V Leiden Molecule, a Mutated Form of Factor V, from Plasma of Homozygous Patient -- A Simple Volume Related Model of Arterial Blood Pressure Generation -- Tumor, Cancer and Oncology -- Strikingly High Respiratory Quotients: A Further Characteristic of the Tumor Pathophysiome -- Endogenous Hypoxia Markers: Case Not Proven! -- RAD18 Signals DNA Polymerase IOTA to Stalled Replication Forks in Cells Entering S-phase with DNA Damage -- Alanine in HI: A Silent Mutation Cries Out! -- Biomathematics in Cancer Detection: Simulation of Lipogenesis in Cancer -- Activity of Drug Efflux Transporters in Tumor Cells Under Hypoxic Conditions -- Antioxidants Reduce Consequences of Radiation Exposure -- Anti-Cancer Effect of Resveratrol is Associated with Induction of Apoptosis via a Mitochondrial Pathway Alignment -- Tissue Engineering -- Computationally Determined Shear on Cells Grown in Orbiting Culture Dishes -- Formation of Capillary Tube-like Structures on Micropatterned Biomaterials -- Bio-Instrumentation -- Error Analysis of Finite-Spectral-Linewidth Illumination in Optical Oximetry Systems -- Changes in the Attenuation of Near Infrared Spectra by the Healthy Adult Brain During Hypoxaemia Cannot be Accounted for Solely by Changes in the Concentrations of Oxy- and Deoxy-Haemoglobin -- Assessment of Oxygenation and Perfusion in the Tongue and Oral Mucosa by Visible Spectrophotometry and Laser Doppler Flowmetry in Healthy Subjects -- Cerebral Tissue Oxygen Saturation Calculated Using Low Frequency Haemoglobin Oscillations Measured by Near Infrared Spectroscopy in Adult Ventilated Patients -- Biosensor for Diagnosing Factor V Leiden, A Single Amino Acid Mutated Abnormality of Factor V -- Scanning Laser Ophthalmoscope-particle Tracking Method to Assess Blood Velocity During Hypoxia and Hyperoxia -- Nano-Bio Technology -- Highly Sensitive Rapid, Reliable, and Automatic Cardiovascular Disease Diagnosis with Nanoparticle Fluorescence Enhancer and Mems -- Tumor-specific Nano-entities for Optical Detection and Hyperthermic Treatment of Breast Cancer -- LHRH Receptor Targeted Therapy for Breast Cancer -- Translational and Clinical Studies -- Saturation of Hemoglobin in Intracranial Arteries is Similar in Patients with Hemodynamically Relevant and Irrelevant Stenosis of the Internal Carotid Artery -- A Three-tiered Approach for Calibration of a Biosensor to Detect Estrogen Mimics -- Biosensors for Detecting Estrogen-like Molecules and Protein Biomarkers -- Modeling and Analysis of Metabolism and Transport -- Muscle Oxygen Uptake Differs from Consumption Dynamics During Transients in Exercise -- Modeling Oxygenation and Selective Delivery of Drug Carriers Post-Myocardial Infarction -- Hypobaric Hypoxia Reduces GLUT2 Transporter Content in Rat Jejunum more than in Ileum -- Modeling Oxygen and Carbon Dioxide Transport and Exchange Using a Closed Loop Circulatory System -- Effect of Alternate Energy Substrates on Mammalian Brain Metabolism During Ischemic Events -- Cerebral Blood Flow Adaptation to Chronic Hypoxia -- Mitochondrial Dysfunction in Aging Rat Brain Following Transient Global Ischemia -- Others -- Measurement of Cerebral Tissue Oxygenation in Young Healthy Volunteers During Acetazolamide Provocation: A Transcranial Doppler and Near-Infrared Spectroscopy Investigation -- Measurement of Frontal Lobe Functional Activation and Related Systemic Effects: A Near-Infrared Spectroscopy Investigation.

In: Springer Nature eBook

Additional Edition: Printed edition: ISBN 9780387521145

Additional Edition: Printed edition: ISBN 9781441945181

Additional Edition: Printed edition: ISBN 9780387749105

Language: English

DOI: 10.1007/978-0-387-74911-2

URL: https://doi.org/10.1007/978-0-387-74911-2

UID:

Format: XXXVIII, 516 p. 179 illus., 15 illus. in color. , online resource.

Edition: 1st ed. 2010.

ISBN: 9781441912411

Series Statement: Advances in Experimental Medicine and Biology, 662

Content: This book covers all aspects involved in uptake of oxygen from the air, transport by blood stream, and its ultimate consumption in the cell in various organs as discussed at the 36th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) held in Sapporo, Japan in August 2008. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biomedical engineering, physiology, biochemistry, molecular biology, and clinical medicine.

In: Springer Nature eBook

Additional Edition: Printed edition: ISBN 9781441912527

Additional Edition: Printed edition: ISBN 9781461425380

Additional Edition: Printed edition: ISBN 9781441912398

Language: English

DOI: 10.1007/978-1-4419-1241-1

URL: https://doi.org/10.1007/978-1-4419-1241-1

UID:

Format: XXX, 374 p. , online resource.

Edition: 1st ed. 2011.

ISBN: 9781441977564

Series Statement: Advances in Experimental Medicine and Biology, 701

Content: Based on the 2009 proceedings of the 37th annual ISOTT conference, this volume covers all aspects of oxygen delivery to tissue, everything from near infrared spectroscopy, tumor biology, angiogenesis and mitochondrial metabolism to systems modeling, gas transport, hypoxic adaptation and exercise physiology. Special emphasis is placed on methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biological bases for pathology related to tissue oxygenation. This multidisciplinary volume includes contributions from scientists, engineers, clinicians and mathematicians and is aimed and students and experts from a range of research fields.

Note: Near Infrared Spectroscopy.The Western Reserve, Edward Morley and Oxygen.Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome c Oxidase in Traumatic Brain Injury Patients during Hypercapnoea: A Broadband NIRS Study.Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements using NIRS during a Valsalva Manoeuvre.Speech Therapy Changes Blood Circulation and Oxygenation in the Brain and Muscle: A Near-Infrared Spectrophotometry Study -- Oxygen Sensors and Measurement.Evaluation of Lithium Naphthalocyanine (LiNc) Microcrystals for Biological EPR Oximetry.Challenges to Intestinal pO2 Measurement Using EPR.Quantification of Systemic Interference in Optical Topography Data during Frontal Lobe and Motor Cortex Activation: An Independent Component Analysis.Measuring Oxygen in Living Tissue: Intravascular, Interstitial and "Tissue" Oxygen Measurements.Cerebral Oxygenation of the Cortex and Striatum following Normobaric Hyperoxia and Mild Hypoxia in Rats by EPR Oximetry Using Multi-Probe Implantable Resonators.31P-MRS Studies of Melanoma Xenograft Metastatic Potential.Modulation of Tumor Hypoxia by Topical Formulations with Vasodilators for Enhancing Therapy -- Blood and Blood Substitutes.MP4, A Vasodilatory PEGylated Hemoglobin.Zymogen Protein C to Prevent Clotting Without Bleeding During Invasive Medical Procedures -- Tumor Biology.Oxygenation Status of Urogenital Tumors.Tumor pO2 as a Surrogate Marker to Identify Therapeutic Window during Metronomic Chemotherapy of 9L Gliomas.Hypoxia-induced Extracellular Acidosis Increases p-glycoprotein activity and chemoresistance in tumors in vivo via p38 signaling pathway.Evidence Against a Major Role for TKTL-1 in Hypoxic and Normoxic Cancer Cells.NMR Metabolic and Physiological Markers of Therapeutic Response.Characterizing Breast Cancer Mouse Xenografts with T1p-MRI: A Preliminary Study.Effect of AEM Energy Applicator Configuration on Magnetic Nanoparticle Mediated Hyperthermia for Breast Cancer.Highly Specific, NIR Fluorescent Contrast Agent with Emission Controlled by Gold Nanoparticle -- Presidential Symposium.Oral Pioglitazone Reduces Infarction Volume and Improves Neurologic Function Following MCAO in Rats -- Angiogenesis.Chronic Mild Hypoxia Ameliorates Chronic Inflammatory Activity in Myelin Oligodendrocyte Glycoprotein (MOG) Peptide Induced Experimental Autoimmune Encephalomyelitis (EAE).Effect of Oxygenation on Stem-Cell Therapy for Myocardial Infarction -- Mitochondrial Metabolism.Regulation of Cytosolic and Mitochondrial Oxidation via Malate-Aspartate Shuttle: An Observation Using Dynamic 13C NMR Spectroscopy.In Vivo Assessment of Oxygen Consumption via Deuterium Magnetic Resonance.Elevated Mitochondrial DNA Copy Number and POL- Expression but decreased Expression of TFAM in Murine Intestine following Therapeutic Dose Irradiation.Heterogeneity of Mitochondrial Redox State in Premalignant Pancreas in a PTEN Null Transgenic Mouse Model.Potential Application of 17O MRI to Human Ischemic Stroke -- Development.Fetal Cerebral Oxygenation: The Homeostatic Role of Vascular Adaptations to Hypoxic Stress.Impaired Cerebral Autoregulation Using Near-Infrared Spectroscopy and its Relation to Clinical Outcomes in Premature Infants -- Systems Modeling.Variable ATP Yields and Uncoupling of Oxygen Consumption in Human Brain.Interpretation of NMR Spectroscopy Human Brain Data with Multi-Compartment Computational Model of Cerebral Metabolism.Regional Brain Blood Flow in Mouse: Quantitative Measurement Using Single-Pass Radio-Tracer Method and Mathematical Algorithm -- Microcirculation and Wound Healing.Wound Healing in Diabetes: Hemorheological and Microcirculatory Aspects.Modeling O2-dependent Effects of Nitrite Reductase Activity in Blood and Tissue on Coupled NO and O2 Transport around Arterioles.Skin SO2 Measurement Using Visible Lightguide Spectrophotometry in a Black Population: A Feasibility Study.Antioxidant Properties 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Exercise.Estimation of Muscle Fatigue Using Surface Electromyography and Near-Infrared Spectroscopy.

In: Springer Nature eBook

Additional Edition: Printed edition: ISBN 9781461428534

Additional Edition: Printed edition: ISBN 9781441977557

Additional Edition: Printed edition: ISBN 9781441977571

Language: English

DOI: 10.1007/978-1-4419-7756-4

URL: https://doi.org/10.1007/978-1-4419-7756-4