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  • 1
    Online Resource
    Online Resource
    Living and working with the new medical technologies : intersections of inquiry (2000)
    Cambridge :Cambridge University Press,
    Details
    UID:
    almafu_9960119842802883
    Format: 1 online resource (ix, 295 pages) : , digital, PDF file(s).
    ISBN: 0-511-83927-8 , 0-511-62176-0
    Series Statement: Cambridge studies in medical anthropology ; 8
    Content: This stimulating collection of essays is the product of face-to-face dialogues among anthropologists, sociologists, and philosopher-historians, all of whom focus their attention on the newly created biomedical technologies and their application in practice. Drawing on ethnographic and historical case studies, the authors show how biomedical technologies are produced through the agencies of tools and techniques, scientists and doctors, funding bodies, patients, clients, and the public. Despite shared concerns, these essays reveal that the authors have achieved no consensus about the objectives of their research, and the deep epistemological divides clearly remain - making for provocative reading.
    Note: Title from publisher's bibliographic system (viewed on 05 Oct 2015). , Beyond nature and culture: modes of reasoning in the age of molecular biology and medicine / Hans-Jörg Rheinberger -- Epochs, presents, events / Paul Rabinow -- Trustworthy knowledge and desperate patients: clinical tests for new drugs from cancer to AIDS / Ilana Löwy -- Pathology and the clinic: an ethnographic presentation of two atheroscleroses / Annemarie Mol -- "Real compared to what?": diagnosing leukemias and lymphomas / Peter Keating and Alberto Cambrosio. , History, hystery and psychiatric styles of reasoning / Allan Young -- Screening the body: the pap smear and the mammogram / Patricia A. Kaufert -- Extra chromosomes and blue tulips: medico-familial interpretations / Rayna Rapp -- When explanations rest: "good-enough" brain science and the new socio-medical disorders / Joseph Dumit -- On dying twice: culture, technology and the determination of death / Margaret Lock -- The practice of organ transplants: networks, documents, translations / Veena Das. , English
    Additional Edition: ISBN 0-521-65568-4
    Additional Edition: ISBN 0-521-65210-3
    Language: English
    URL: Volltext  (lizenzpflichtig)
    URL: https://doi.org/10.1017/CBO9780511621765
    URL: https://doi.org/10.1017/CBO9780511621765
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
    Stabi Berlin
    HU Berlin
    FU Berlin
    UB Potsdam
  • 2
    Book
    Book
    Biomedical platforms : realigning the normal and the pathological in late-twentieth-century medicine (2003)
    Cambridge, Mass. [u.a.] :MIT Press,
    Details
    UID:
    almafu_BV016421007
    Format: XIV, 544 S. : , Ill., graph. Darst.
    ISBN: 0-262-11276-0
    Series Statement: Inside technology
    Note: Includes bibliographical references (p. [457]-525) and index
    Language: English
    Subjects: Ethnology , Sociology
    RVK:
    LC 56000
    RVK:
    MS 6000
    Keywords: Medizin ; Biologie ; Interdisziplinäre Forschung ; Wissenschaftlicher Fortschritt ; Medizin ; Wissenschaftlicher Fortschritt ; Immunphänotypisierung ; Krankheitsbegriff ; Bibliografie
    URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010154517&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
    URL: Inhaltsverzeichnis
    URL: http://www.loc.gov/catdir/toc/fy042/2002044414.html
    URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010154517&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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  • 3
    Online Resource
    Online Resource
    Cancer on trial : oncology as a new style of practice (2012)
    Chicago, Ill. :University of Chicago Press,
    Details
    UID:
    almahu_9949597528602882
    Format: 1 online resource (xviii, 456 p.) : , ill.
    ISBN: 9780226428932 (ebook) :
    Content: This title charts the emergence of a clinical field - medical oncology - for which experimental protocols have become routinized as a form of normal practice.
    Additional Edition: Print version ISBN 9780226428918
    Language: English
    URL: Chicago scholarship online
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    HU Berlin
  • 4
    Book
    Book
    Cancer on trial : oncology as a new style of practice (2012)
    Chicago [u.a.] : Univ. of Chicago Press
    Details
    UID:
    gbv_1601869630
    Format: xviii, 456 p. , ill. , 24 cm
    ISBN: 9780226428918 , 0226428915
    Note: Formerly CIP Uk. - Includes bibliographical references and index , From "nonentity" to global network: the rise of a new style of biomedical practice -- An early career in clinical oncology -- About this book -- A capsule history of cancer clinical trials -- Cancer clinical trials as a new style of practice -- The protocol -- Before there were trials -- Cancer hospitals and cancer institutes -- Diagnosing cancer -- Treating cancer -- Prognosticating cancer -- Testing therapies -- The emergence of clinical cancer research (1955-66) -- A landmark clinical trial -- Curing leukemia: the vamp trial -- A collective undertaking -- The elements of innovation -- What about the patients? -- The collective turn: cooperative groups as epistemic organizations -- Assembling the US cooperative system -- Screening for drugs: from mice to humans -- Tinkering with the cooperative group structure -- Meanwhile in Europe -- Clinical trial statistics -- What is a random sample? -- What is statistical significance? -- Statisticians, statistics, and early cooperative clinical trials -- Statisticians at the NIH -- Statisticians in Paris -- Fabricating the tools of the trade -- Controversial methods -- The emergence of the phase system -- Criticism and the redefinition of clinical cancer trials as an autonomous form of research -- Clinical cancer research under fire -- The reorganization of screening and clinical trials in the United States -- Surgery and radiotherapy in the cooperative groups -- An avalanche of numbers from the new style of practice (1965-89) -- A web of trials -- Breast cancer and its trials -- The lessons of the breast cancer trials -- The emergence of combination chemotherapy -- The multiple meanings of breast cancer trials -- Statisticians, data centers, and the organization of large-scale clinical trials -- Centers of calculation: us statisticians and the data center -- The mechanics of data production -- Meanwhile in Europe, take two -- Back in the USA: group statisticians and NCI statisticians -- Insiders' dissent: the randomization debate -- A relational space of substances and regimens -- The clinical evaluation of substances -- Screening substances: the animal screen -- Procuring compounds -- Oncopolitics? reshaping collaborative research -- Centralization or coordination? the European debate -- Clinical trials as clinical research: the US debate -- Oncology in the community -- Targeted therapy, targeted trials (1990-2006) -- Second interlude: molecular biology and oncogenes -- The rise of molecular biology -- Cancer and molecular biology: 1960-80 -- The clinical isolation of human oncogenes -- Oncogenes and oncoproteins since 1982 -- Magic bullets? the Gleevec trials -- Molecular biology and targeted substances -- The trials of a targeted therapy -- Where did Gleevec come from? -- Monitoring data, managing risks -- A medical oncologist and his patients -- Patients and activists -- Targeted therapy and clinical cancer research -- Introduction: molecular biology and translational research -- Molecular biology and the US cooperative groups -- The reorganization of the drug discovery process and the transformation of the NCI screen -- Clinical trials in a targeted age -- More oncopolitics -- Looking back and looking forward -- The observational alternative to clinical cancer trials -- Comparative effectiveness and clinical trials.
    Language: English
    Subjects: Medicine
    RVK:
    XH 3200
    Keywords: Krebs ; Cytostatikum ; Chemotherapie ; Klinische Prüfung ; Onkologie ; Krebsforschung
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  • 5
    Book
    Book
    Exquisite specificity : the monoclonal antibody revolution (1995)
    New York [u.a.] : Oxford University Press
    Details
    UID:
    gbv_279012632
    Format: XXI, 243 S. , Ill., graph. Darst., Kt.
    ISBN: 0195097416
    Note: Includes bibliographical references and index
    Language: English
    Keywords: Monoklonaler Antikörper ; Hybridomtechnik ; Geschichte ; Monoklonaler Antikörper
    URL: http://www.loc.gov/catdir/enhancements/fy0637/95016982-d.html
    URL: http://www.loc.gov/catdir/enhancements/fy0637/95016982-t.html
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  • 6
    Online Resource
    Online Resource
    Cancer on trial : oncology as a new style of practice (2012)
    Chicago :University of Chicago Press,
    Details
    UID:
    almahu_9948315711802882
    Format: xviii, 456 p.
    Edition: Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
    Note: From "nonentity" to global network: the rise of a new style of biomedical practice -- An early career in clinical oncology -- About this book -- A capsule history of cancer clinical trials -- Cancer clinical trials as a new style of practice -- The protocol -- Before there were trials -- Cancer hospitals and cancer institutes -- Diagnosing cancer -- Treating cancer -- Prognosticating cancer -- Testing therapies -- The emergence of clinical cancer research (1955-66) -- A landmark clinical trial -- Curing leukemia: the vamp trial -- A collective undertaking -- The elements of innovation -- What about the patients? -- The collective turn: cooperative groups as epistemic organizations -- Assembling the US cooperative system -- Screening for drugs: from mice to humans -- Tinkering with the cooperative group structure -- Meanwhile in Europe -- Clinical trial statistics -- What is a random sample? -- What is statistical significance? -- Statisticians, statistics, and early cooperative clinical trials -- Statisticians at the NIH -- Statisticians in Paris -- Fabricating the tools of the trade -- Controversial methods -- The emergence of the phase system -- Criticism and the redefinition of clinical cancer trials as an autonomous form of research -- Clinical cancer research under fire -- The reorganization of screening and clinical trials in the United States -- Surgery and radiotherapy in the cooperative groups -- An avalanche of numbers from the new style of practice (1965-89) -- A web of trials -- Breast cancer and its trials -- The lessons of the breast cancer trials -- The emergence of combination chemotherapy -- The multiple meanings of breast cancer trials -- Statisticians, data centers, and the organization of large-scale clinical trials -- Centers of calculation: us statisticians and the data center -- The mechanics of data production -- Meanwhile in Europe, take two -- Back in the USA: group statisticians and NCI statisticians -- Insiders' dissent: the randomization debate -- A relational space of substances and regimens -- The clinical evaluation of substances -- Screening substances: the animal screen -- Procuring compounds -- Oncopolitics? reshaping collaborative research -- Centralization or coordination? the European debate -- Clinical trials as clinical research: the US debate -- Oncology in the community -- Targeted therapy, targeted trials (1990-2006) -- Second interlude: molecular biology and oncogenes -- The rise of molecular biology -- Cancer and molecular biology: 1960-80 -- The clinical isolation of human oncogenes -- Oncogenes and oncoproteins since 1982 -- Magic bullets? the Gleevec trials -- Molecular biology and targeted substances -- The trials of a targeted therapy -- Where did Gleevec come from? -- Monitoring data, managing risks -- A medical oncologist and his patients -- Patients and activists -- Targeted therapy and clinical cancer research -- Introduction: molecular biology and translational research -- Molecular biology and the US cooperative groups -- The reorganization of the drug discovery process and the transformation of the NCI screen -- Clinical trials in a targeted age -- More oncopolitics -- Looking back and looking forward -- The observational alternative to clinical cancer trials -- Comparative effectiveness and clinical trials.
    Language: English
    Keywords: Electronic books.
    URL: Click to View
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    HU Berlin
  • 7
    Online Resource
    Online Resource
    Cancer on trial : oncology as a new style of practice (2012)
    Chicago :University of Chicago Press,
    Details
    UID:
    almafu_9959228803302883
    Format: 1 online resource (476 p.)
    Edition: 1st ed.
    ISBN: 1-283-36261-9 , 9786613362612 , 0-226-42893-1
    Content: Until the early 1960's, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960's, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
    Note: Description based upon print version of record. , From "nonentity" to global network: the rise of a new style of biomedical practice -- An early career in clinical oncology -- About this book -- A capsule history of cancer clinical trials -- Cancer clinical trials as a new style of practice -- The protocol -- Before there were trials -- Cancer hospitals and cancer institutes -- Diagnosing cancer -- Treating cancer -- Prognosticating cancer -- Testing therapies -- The emergence of clinical cancer research (1955-66) -- A landmark clinical trial -- Curing leukemia: the vamp trial -- A collective undertaking -- The elements of innovation -- What about the patients? -- The collective turn: cooperative groups as epistemic organizations -- Assembling the US cooperative system -- Screening for drugs: from mice to humans -- Tinkering with the cooperative group structure -- Meanwhile in Europe -- Clinical trial statistics -- What is a random sample? -- What is statistical significance? -- Statisticians, statistics, and early cooperative clinical trials -- Statisticians at the NIH -- Statisticians in Paris -- Fabricating the tools of the trade -- Controversial methods -- The emergence of the phase system -- Criticism and the redefinition of clinical cancer trials as an autonomous form of research -- Clinical cancer research under fire -- The reorganization of screening and clinical trials in the United States -- Surgery and radiotherapy in the cooperative groups -- An avalanche of numbers from the new style of practice (1965-89) -- A web of trials -- Breast cancer and its trials -- The lessons of the breast cancer trials -- The emergence of combination chemotherapy -- The multiple meanings of breast cancer trials -- Statisticians, data centers, and the organization of large-scale clinical trials -- Centers of calculation: us statisticians and the data center -- The mechanics of data production -- Meanwhile in Europe, take two -- Back in the USA: group statisticians and NCI statisticians -- Insiders' dissent: the randomization debate -- A relational space of substances and regimens -- The clinical evaluation of substances -- Screening substances: the animal screen -- Procuring compounds -- Oncopolitics? reshaping collaborative research -- Centralization or coordination? the European debate -- Clinical trials as clinical research: the US debate -- Oncology in the community -- Targeted therapy, targeted trials (1990-2006) -- Second interlude: molecular biology and oncogenes -- The rise of molecular biology -- Cancer and molecular biology: 1960-80 -- The clinical isolation of human oncogenes -- Oncogenes and oncoproteins since 1982 -- Magic bullets? the Gleevec trials -- Molecular biology and targeted substances -- The trials of a targeted therapy -- Where did Gleevec come from? -- Monitoring data, managing risks -- A medical oncologist and his patients -- Patients and activists -- Targeted therapy and clinical cancer research -- Introduction: molecular biology and translational research -- Molecular biology and the US cooperative groups -- The reorganization of the drug discovery process and the transformation of the NCI screen -- Clinical trials in a targeted age -- More oncopolitics -- Looking back and looking forward -- The observational alternative to clinical cancer trials -- Comparative effectiveness and clinical trials. , English
    Additional Edition: ISBN 0-226-42891-5
    Language: English
    DOI: 10.7208/9780226428932
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Open Access Request
    FU Berlin
  • 8
    Online Resource
    Online Resource
    Biomedical platforms : realigning the normal and the pathological in late-twentieth-century medicine (2003)
    Cambridge, Mass. :MIT Press,
    Details
    UID:
    almafu_9959226971702883
    Format: 1 online resource (xiv, 544 pages) : , illustrations.
    ISBN: 0-262-27687-9 , 0-585-48018-4
    Series Statement: Inside technology
    Content: Since the end of World War II, biology and medicine have merged in remarkably productive ways. In this book Peter Keating and Alberto Cambrosio analyze the transformation of medicine into biomedicine and its consequences, ranging from the recasting of hospital architecture to the redefinition of the human body, disease, and therapeutic practices. To describe this new alignment between the normal and the pathological, the authors introduce the notion of the biomedical platform. Defined as a specific configuration of instruments, individuals, and programs, biomedical platforms generate routines, entities, and activities, held together by standard reagents and protocols. Biological entities such as cell surface markers, oncogenes, and DNA profiles now exist as both normal biological components of the organism and as pathological signs--that is, as biomedical substances. The notion of a biomedical platform allows researchers interested in the development of contemporary medicine to describe events and processes overlooked by other approaches.The authors focus on a specific biomedical platform known as immunophenotyping. They describe its emergence as an experimental system with roots in biology (immunology) and pathology (oncology). They recount how this experimental system was transformed into a biomedical platform initially for the diagnosis of leukemia and subsequently for other diseases such as AIDS. Through this case study, they show that a biomedical platform is the bench upon which conventions concerning the biological or normal are connected with conventions concerning the medical or pathological. They observe that new platforms are often aligned with existing ones and integrated into an expanding set of clinical-biological strategies.
    Note: Bibliographic Level Mode of Issuance: Monograph , English
    Additional Edition: ISBN 0-262-11276-0
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    FU Berlin
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