Kooperativer Bibliotheksverbund

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Format: 1 online resource (323 pages)

ISBN: 0-12-824298-1

Note: Front Cover -- The Lymphatic System in Colorectal Cancer -- Copyright Page -- Contents -- List of contributors -- Preface -- 1 Basic Concepts -- 1 Hypoxic signaling in lymphatic colorectal cancer metastasis -- 1.1 Introduction -- 1.2 Hypoxic signaling in the tumor microenvironment -- 1.3 Hypoxia and metastatic dissemination -- 1.3.1 EMT, cell motility, and invasion -- 1.3.2 Lymphatic intravasation and extravasation -- 1.3.3 Anoikis, mitochondrial hyperpolarization, and lymphatic dissemination -- 1.3.4 Lymphatic niche formation and clonal expansion -- 1.4 Therapeutic perspectives -- Conflicts of interest -- References -- 2 Biomechanical aspects of the normal and cancer-associated lymphatic system -- 2.1 Introduction -- 2.2 Biomechanics of the normal lymphatic system -- 2.2.1 Mechanical properties of the interstitium -- 2.2.2 Interstitial flow and lymph formation -- 2.2.3 Lymphatic endothelial cells and initial lymphatics -- 2.2.4 Collecting lymphatics and lymphangions -- 2.2.5 Lymph nodes -- 2.3 Biomechanics of lymphatic metastasis -- 2.3.1 The biomechanical environment of cancer tissue -- 2.3.2 Lymphangiogenesis in cancer -- 2.3.3 Interstitial and lymphatic transport in cancer tissue -- 2.3.4 Mechanisms of cancer cell invasion of initial lymphatics -- 2.3.5 The metastatic lymph node -- 2.4 Conclusions and future perspectives -- References -- 3 Mechanisms of lymphatic spread in colon cancer: insights from molecular and genetic studies -- 3.1 Introduction -- 3.2 Mechanisms of the lymphatic system -- 3.2.1 Lymph formation and movement -- 3.3 Tumor microenvironment -- 3.4 Colorectal cancer staging and treatment -- 3.4.1 Colorectal cancer staging -- 3.4.2 Colorectal cancer treatment -- 3.5 Evolutionary mechanisms of lymph node metastasis -- 3.5.1 Linear models -- 3.5.1.1 Model 1 -- 3.5.1.2 Intratumor heterogeneity -- 3.5.1.3 Model 2. , 3.5.1.4 Parallel model -- 3.5.1.5 Model 3 -- 3.6 Molecular markers of colorectal cancer spread -- 3.7 Molecular markers of metastases -- 3.8 Conclusions -- Conflict of interest -- References -- 4 Anatomy and embryology of the lymphatic system of the colon and rectum -- 4.1 Introduction -- 4.2 Embryology of the lymphatic system -- 4.2.1 Molecular mechanisms -- 4.2.2 The lymph sacs -- 4.3 Anatomy of the lymphatic system -- 4.3.1 Lymphatic capillaries -- 4.3.2 Collecting lymphatic vessels and lymph nodes -- 4.3.3 Lymphatic trunks and ducts -- 4.4 Anatomy of the lymphatic system of the colon and rectum -- 4.4.1 Macroscopic anatomy of the colon and rectum -- 4.4.2 Vascularization of the colon and rectum -- 4.4.3 Lymphatic vessel anatomy in the mesocolon -- 4.4.4 Lymphatic vessel anatomy in the mesorectum -- 4.4.5 Lymphatic drainage of the colon and rectum -- 4.4.5.1 Lymphatic drainage of the colon -- 4.4.5.2 Lymphatic drainage of the rectum -- 4.4.5.3 Preaortic and lumbar lymph nodes -- 4.4.5.4 Lumbar and intestinal lymph trunks and the cisterna chyli -- 4.4.5.5 The thoracic duct -- 4.5 Conclusion -- References -- 2 Pathology and Imaging -- 5 Imaging of colorectal nodal disease -- 5.1 Introduction -- 5.2 Staging, segmentation, and endoscopic detection -- 5.2.1 Staging -- 5.2.2 Segmentation and endoscopic detection -- 5.2.2.1 Colorectal polyps segmentation -- 5.2.2.2 Colorectal tumors segmentation -- 5.3 Metastasis classification and prediction -- 5.3.1 Pathological classification -- 5.3.2 Radiological LNM classification -- 5.3.2.1 Metachronous metastasis prediction -- 5.4 Treatment response, recurrence, and survival -- 5.5 Summary and future directions -- References -- 6 Tumor deposits in colorectal cancer -- 6.1 Introduction -- 6.2 Definition of tumor deposits -- 6.3 The origins and biology of tumor deposits -- 6.3.1 Where do tumor deposits come from?. , 6.3.2 The biological mechanisms underlying tumor deposit development -- 6.4 Staging of tumor deposits -- 6.5 Prognostic value of tumor deposits -- 6.6 Tumor deposits and neoadjuvant therapies -- 6.7 Pathological assessment of tumor deposits: interobserver variation -- 6.7.1 Interobserver agreement regarding tumor deposits in previous TNM editions -- 6.7.2 Interobserver agreement regarding tumor deposits in the TNM 8th edition -- 6.7.3 How to improve interobserver variation regarding tumor deposits? -- 6.8 Radiological assessment of tumor deposits: advances and challenges -- 6.8.1 Tumor deposits in colon cancer, identification by CT -- 6.8.2 Tumor deposits in rectal cancer, identification by MRI -- 6.8.3 A radiological concept regarding the origin of tumor deposits -- 6.8.4 The future of tumor deposits in radiology -- References -- 7 Lymph node classification in colorectal cancer: tumor node metastasis versus the Japanese system -- 7.1 Japanese D3 lymphadenectomy -- 7.1.1 Japanese lymph node classification -- 7.1.2 Concept of Japanese lymphadenectomy -- 7.1.3 Lateral lymph node dissection -- 7.1.4 Japanese D3 versus complete mesocolic excision -- 7.2 Tumor node metastasis versus Japanese lymph node classification -- 7.3 Conclusion -- References -- 8 Detection and significance of micrometastases and isolated tumor cells in lymph nodes of colorectal cancer resections -- 8.1 Definition of micrometastases and isolated tumor cells -- 8.1.1 AJCC/UICC definition -- 8.1.2 Methods of detection -- 8.1.3 Biological significance -- 8.1.4 Reporting -- 8.1.5 Summary -- 8.2 Micrometastases and isolated tumor cells in colorectal cancer -- 8.2.1 Implications in colorectal cancer -- 8.2.2 Occult disease in lymph nodes in colorectal cancer -- 8.2.3 Recommendations for standardized histopathological analysis of lymph nodes. , 8.3 Micrometastases and isolated tumor cells in sentinel lymph-node biopsy in colorectal cancer -- 8.3.1 Sentinel lymph-node mapping with ultra-staging -- 8.3.2 Sentinel lymph-node biopsy in colorectal cancer -- 8.4 Micrometastases and isolated tumor cells after neoadjuvant therapy -- 8.5 Differential diagnosis of micrometastases and isolated tumor cells -- 8.6 Conclusion -- References -- 9 Anatomical and temporal patterns of lymph node metastasis in colorectal cancer -- 9.1 Introduction -- 9.2 Mechanisms of lymphatic spread in colon cancer -- 9.3 Temporal patterns of metastasis in colon cancer -- 9.3.1 Evidence from circulating and tissue biomarkers -- 9.3.2 Evidence from genomic and phylogenetic studies -- 9.3.3 Evidence from growth rate of primary and metastatic colorectal tumors -- 9.3.4 Evidence from autopsy findings in metastatic colorectal cancer -- 9.3.5 Evidence from clinical studies -- 9.3.5.1 Segmental resection versus hemicolectomy -- 9.3.5.2 Extra-mesenteric lymph node dissection -- 9.3.5.3 Central (apical) lymph node resection -- 9.3.5.4 High versus low ligation of the inferior mesenteric artery -- 9.3.5.5 Complete mesocolic excision and D3 dissection versus standard resection -- 9.3.5.6 Effect of extended lymphadenectomy on isolated lymph node recurrence -- 9.3.5.7 Lymph node counts and outcome -- 9.4 Anatomical patterns of lymph node metastasis in colon cancer -- 9.5 Conclusion and implications for research -- References -- 3 Treatment -- 10 Neoadjuvant treatment and lymph node metastasis in rectal cancer -- 10.1 Introduction -- 10.2 Importance of lymph node yield -- 10.3 Lymph node yield -- 10.4 Neoadjuvant therapy and lymph node yield -- 10.5 Lymph node ratio -- 10.6 Impact of nodal involvement with complete clinical response after neoadjuvant therapy -- 10.7 Effects of total neoadjuvant therapy -- 10.8 Conclusion -- References. , Further reading -- 11 Complete mesocolic excision in colon cancer -- 11.1 Introduction -- 11.2 Outline of the key anatomy -- 11.3 Principles of CME surgery -- 11.3.1 Role of minimally invasive CME surgery -- 11.4 Oncological benefits of CME -- 11.4.1 Which patients benefit from CME? -- 11.5 Potential limitations of CME and associated controversies -- 11.5.1 Complications -- 11.5.2 Technical difficulties -- 11.5.3 CME in transverse colon cancer -- 11.6 Importance of pathological quality control in CME surgery -- 11.6.1 Integrity of the mesocolon (plane of surgery) -- 11.6.2 Distance between the tumor and the central arterial ligation point -- 11.6.3 Length of bowel resected -- 11.6.4 Lymph node yield -- 11.6.5 Specimen photography -- 11.7 Conclusion -- References -- 12 Japanese D3 dissection in cancer of the colon: technique and results -- 12.1 Introduction -- 12.2 History of lymphadenectomy for colon cancer in Japan -- 12.2.1 Japanese classification and Japanese guidelines -- 12.3 Basic principles of lymph node dissection in Japan -- 12.4 Changes in the recommended area of lymph node dissection in Japan -- 12.5 Current classifications of lymph node metastasis (N) and lymph node dissection (D) in Japan -- 12.5.1 Basic principles of regional lymph node classification -- 12.6 Lymph node groups and station numbers -- 12.7 Classification of lymph node metastases (N) -- 12.8 Classification of lymph node dissection (D) -- 12.9 Technique of Japanese D3 dissection for colon cancer -- 12.10 Cecum cancer -- 12.11 Ascending colon cancer -- 12.12 Transverse colon cancer -- 12.13 Descending colon cancer -- 12.14 Sigmoid colon cancer -- 12.15 Preservation of the LCA for left-sided colon cancer -- 12.16 Outcomes of Japanese D3 dissection for colon cancer -- 12.16.1 D3 lymphadenectomy versus D2 lymphadenectomy. , 12.17 Current recommendations of the Japanese guidelines, 2019.

Additional Edition: ISBN 0-12-824297-3

Language: English

UID:

Format: 1 online resource (603 pages)

Edition: 1

ISBN: 9783642478369

Series Statement: Handbuch der Speziellen Pathologischen Anatomie und Histologie Series ; v.3 / 2

Additional Edition: Print version: Berblinger, W. Atmungswege und Lungen Berlin, Heidelberg : Springer Berlin / Heidelberg,c1930 ISBN 9783540011217

Keywords: Electronic books.

URL: https://ebookcentral.proquest.com/lib/th-brandenburg/detail.action?docID=6861176

UID:

Format: 1 online resource (711 pages)

Edition: 1

ISBN: 9783642478383

Series Statement: Handbuch der Speziellen Pathologischen Anatomie und Histologie Series ; v.3 / 3

Additional Edition: Print version: Arndt, H. J. Atmungswege und Lungen Berlin, Heidelberg : Springer Berlin / Heidelberg,c1931 ISBN 9783540011460

Keywords: Electronic books.

URL: https://ebookcentral.proquest.com/lib/th-brandenburg/detail.action?docID=6853316

UID:

Format: 1 online resource (323 pages)

ISBN: 0-12-824298-1

Note: Front Cover -- The Lymphatic System in Colorectal Cancer -- Copyright Page -- Contents -- List of contributors -- Preface -- 1 Basic Concepts -- 1 Hypoxic signaling in lymphatic colorectal cancer metastasis -- 1.1 Introduction -- 1.2 Hypoxic signaling in the tumor microenvironment -- 1.3 Hypoxia and metastatic dissemination -- 1.3.1 EMT, cell motility, and invasion -- 1.3.2 Lymphatic intravasation and extravasation -- 1.3.3 Anoikis, mitochondrial hyperpolarization, and lymphatic dissemination -- 1.3.4 Lymphatic niche formation and clonal expansion -- 1.4 Therapeutic perspectives -- Conflicts of interest -- References -- 2 Biomechanical aspects of the normal and cancer-associated lymphatic system -- 2.1 Introduction -- 2.2 Biomechanics of the normal lymphatic system -- 2.2.1 Mechanical properties of the interstitium -- 2.2.2 Interstitial flow and lymph formation -- 2.2.3 Lymphatic endothelial cells and initial lymphatics -- 2.2.4 Collecting lymphatics and lymphangions -- 2.2.5 Lymph nodes -- 2.3 Biomechanics of lymphatic metastasis -- 2.3.1 The biomechanical environment of cancer tissue -- 2.3.2 Lymphangiogenesis in cancer -- 2.3.3 Interstitial and lymphatic transport in cancer tissue -- 2.3.4 Mechanisms of cancer cell invasion of initial lymphatics -- 2.3.5 The metastatic lymph node -- 2.4 Conclusions and future perspectives -- References -- 3 Mechanisms of lymphatic spread in colon cancer: insights from molecular and genetic studies -- 3.1 Introduction -- 3.2 Mechanisms of the lymphatic system -- 3.2.1 Lymph formation and movement -- 3.3 Tumor microenvironment -- 3.4 Colorectal cancer staging and treatment -- 3.4.1 Colorectal cancer staging -- 3.4.2 Colorectal cancer treatment -- 3.5 Evolutionary mechanisms of lymph node metastasis -- 3.5.1 Linear models -- 3.5.1.1 Model 1 -- 3.5.1.2 Intratumor heterogeneity -- 3.5.1.3 Model 2. , 3.5.1.4 Parallel model -- 3.5.1.5 Model 3 -- 3.6 Molecular markers of colorectal cancer spread -- 3.7 Molecular markers of metastases -- 3.8 Conclusions -- Conflict of interest -- References -- 4 Anatomy and embryology of the lymphatic system of the colon and rectum -- 4.1 Introduction -- 4.2 Embryology of the lymphatic system -- 4.2.1 Molecular mechanisms -- 4.2.2 The lymph sacs -- 4.3 Anatomy of the lymphatic system -- 4.3.1 Lymphatic capillaries -- 4.3.2 Collecting lymphatic vessels and lymph nodes -- 4.3.3 Lymphatic trunks and ducts -- 4.4 Anatomy of the lymphatic system of the colon and rectum -- 4.4.1 Macroscopic anatomy of the colon and rectum -- 4.4.2 Vascularization of the colon and rectum -- 4.4.3 Lymphatic vessel anatomy in the mesocolon -- 4.4.4 Lymphatic vessel anatomy in the mesorectum -- 4.4.5 Lymphatic drainage of the colon and rectum -- 4.4.5.1 Lymphatic drainage of the colon -- 4.4.5.2 Lymphatic drainage of the rectum -- 4.4.5.3 Preaortic and lumbar lymph nodes -- 4.4.5.4 Lumbar and intestinal lymph trunks and the cisterna chyli -- 4.4.5.5 The thoracic duct -- 4.5 Conclusion -- References -- 2 Pathology and Imaging -- 5 Imaging of colorectal nodal disease -- 5.1 Introduction -- 5.2 Staging, segmentation, and endoscopic detection -- 5.2.1 Staging -- 5.2.2 Segmentation and endoscopic detection -- 5.2.2.1 Colorectal polyps segmentation -- 5.2.2.2 Colorectal tumors segmentation -- 5.3 Metastasis classification and prediction -- 5.3.1 Pathological classification -- 5.3.2 Radiological LNM classification -- 5.3.2.1 Metachronous metastasis prediction -- 5.4 Treatment response, recurrence, and survival -- 5.5 Summary and future directions -- References -- 6 Tumor deposits in colorectal cancer -- 6.1 Introduction -- 6.2 Definition of tumor deposits -- 6.3 The origins and biology of tumor deposits -- 6.3.1 Where do tumor deposits come from?. , 6.3.2 The biological mechanisms underlying tumor deposit development -- 6.4 Staging of tumor deposits -- 6.5 Prognostic value of tumor deposits -- 6.6 Tumor deposits and neoadjuvant therapies -- 6.7 Pathological assessment of tumor deposits: interobserver variation -- 6.7.1 Interobserver agreement regarding tumor deposits in previous TNM editions -- 6.7.2 Interobserver agreement regarding tumor deposits in the TNM 8th edition -- 6.7.3 How to improve interobserver variation regarding tumor deposits? -- 6.8 Radiological assessment of tumor deposits: advances and challenges -- 6.8.1 Tumor deposits in colon cancer, identification by CT -- 6.8.2 Tumor deposits in rectal cancer, identification by MRI -- 6.8.3 A radiological concept regarding the origin of tumor deposits -- 6.8.4 The future of tumor deposits in radiology -- References -- 7 Lymph node classification in colorectal cancer: tumor node metastasis versus the Japanese system -- 7.1 Japanese D3 lymphadenectomy -- 7.1.1 Japanese lymph node classification -- 7.1.2 Concept of Japanese lymphadenectomy -- 7.1.3 Lateral lymph node dissection -- 7.1.4 Japanese D3 versus complete mesocolic excision -- 7.2 Tumor node metastasis versus Japanese lymph node classification -- 7.3 Conclusion -- References -- 8 Detection and significance of micrometastases and isolated tumor cells in lymph nodes of colorectal cancer resections -- 8.1 Definition of micrometastases and isolated tumor cells -- 8.1.1 AJCC/UICC definition -- 8.1.2 Methods of detection -- 8.1.3 Biological significance -- 8.1.4 Reporting -- 8.1.5 Summary -- 8.2 Micrometastases and isolated tumor cells in colorectal cancer -- 8.2.1 Implications in colorectal cancer -- 8.2.2 Occult disease in lymph nodes in colorectal cancer -- 8.2.3 Recommendations for standardized histopathological analysis of lymph nodes. , 8.3 Micrometastases and isolated tumor cells in sentinel lymph-node biopsy in colorectal cancer -- 8.3.1 Sentinel lymph-node mapping with ultra-staging -- 8.3.2 Sentinel lymph-node biopsy in colorectal cancer -- 8.4 Micrometastases and isolated tumor cells after neoadjuvant therapy -- 8.5 Differential diagnosis of micrometastases and isolated tumor cells -- 8.6 Conclusion -- References -- 9 Anatomical and temporal patterns of lymph node metastasis in colorectal cancer -- 9.1 Introduction -- 9.2 Mechanisms of lymphatic spread in colon cancer -- 9.3 Temporal patterns of metastasis in colon cancer -- 9.3.1 Evidence from circulating and tissue biomarkers -- 9.3.2 Evidence from genomic and phylogenetic studies -- 9.3.3 Evidence from growth rate of primary and metastatic colorectal tumors -- 9.3.4 Evidence from autopsy findings in metastatic colorectal cancer -- 9.3.5 Evidence from clinical studies -- 9.3.5.1 Segmental resection versus hemicolectomy -- 9.3.5.2 Extra-mesenteric lymph node dissection -- 9.3.5.3 Central (apical) lymph node resection -- 9.3.5.4 High versus low ligation of the inferior mesenteric artery -- 9.3.5.5 Complete mesocolic excision and D3 dissection versus standard resection -- 9.3.5.6 Effect of extended lymphadenectomy on isolated lymph node recurrence -- 9.3.5.7 Lymph node counts and outcome -- 9.4 Anatomical patterns of lymph node metastasis in colon cancer -- 9.5 Conclusion and implications for research -- References -- 3 Treatment -- 10 Neoadjuvant treatment and lymph node metastasis in rectal cancer -- 10.1 Introduction -- 10.2 Importance of lymph node yield -- 10.3 Lymph node yield -- 10.4 Neoadjuvant therapy and lymph node yield -- 10.5 Lymph node ratio -- 10.6 Impact of nodal involvement with complete clinical response after neoadjuvant therapy -- 10.7 Effects of total neoadjuvant therapy -- 10.8 Conclusion -- References. , Further reading -- 11 Complete mesocolic excision in colon cancer -- 11.1 Introduction -- 11.2 Outline of the key anatomy -- 11.3 Principles of CME surgery -- 11.3.1 Role of minimally invasive CME surgery -- 11.4 Oncological benefits of CME -- 11.4.1 Which patients benefit from CME? -- 11.5 Potential limitations of CME and associated controversies -- 11.5.1 Complications -- 11.5.2 Technical difficulties -- 11.5.3 CME in transverse colon cancer -- 11.6 Importance of pathological quality control in CME surgery -- 11.6.1 Integrity of the mesocolon (plane of surgery) -- 11.6.2 Distance between the tumor and the central arterial ligation point -- 11.6.3 Length of bowel resected -- 11.6.4 Lymph node yield -- 11.6.5 Specimen photography -- 11.7 Conclusion -- References -- 12 Japanese D3 dissection in cancer of the colon: technique and results -- 12.1 Introduction -- 12.2 History of lymphadenectomy for colon cancer in Japan -- 12.2.1 Japanese classification and Japanese guidelines -- 12.3 Basic principles of lymph node dissection in Japan -- 12.4 Changes in the recommended area of lymph node dissection in Japan -- 12.5 Current classifications of lymph node metastasis (N) and lymph node dissection (D) in Japan -- 12.5.1 Basic principles of regional lymph node classification -- 12.6 Lymph node groups and station numbers -- 12.7 Classification of lymph node metastases (N) -- 12.8 Classification of lymph node dissection (D) -- 12.9 Technique of Japanese D3 dissection for colon cancer -- 12.10 Cecum cancer -- 12.11 Ascending colon cancer -- 12.12 Transverse colon cancer -- 12.13 Descending colon cancer -- 12.14 Sigmoid colon cancer -- 12.15 Preservation of the LCA for left-sided colon cancer -- 12.16 Outcomes of Japanese D3 dissection for colon cancer -- 12.16.1 D3 lymphadenectomy versus D2 lymphadenectomy. , 12.17 Current recommendations of the Japanese guidelines, 2019.

Additional Edition: ISBN 0-12-824297-3

Language: English

UID:

Format: 1 online resource (323 pages)

ISBN: 0-12-824298-1

Note: Front Cover -- The Lymphatic System in Colorectal Cancer -- Copyright Page -- Contents -- List of contributors -- Preface -- 1 Basic Concepts -- 1 Hypoxic signaling in lymphatic colorectal cancer metastasis -- 1.1 Introduction -- 1.2 Hypoxic signaling in the tumor microenvironment -- 1.3 Hypoxia and metastatic dissemination -- 1.3.1 EMT, cell motility, and invasion -- 1.3.2 Lymphatic intravasation and extravasation -- 1.3.3 Anoikis, mitochondrial hyperpolarization, and lymphatic dissemination -- 1.3.4 Lymphatic niche formation and clonal expansion -- 1.4 Therapeutic perspectives -- Conflicts of interest -- References -- 2 Biomechanical aspects of the normal and cancer-associated lymphatic system -- 2.1 Introduction -- 2.2 Biomechanics of the normal lymphatic system -- 2.2.1 Mechanical properties of the interstitium -- 2.2.2 Interstitial flow and lymph formation -- 2.2.3 Lymphatic endothelial cells and initial lymphatics -- 2.2.4 Collecting lymphatics and lymphangions -- 2.2.5 Lymph nodes -- 2.3 Biomechanics of lymphatic metastasis -- 2.3.1 The biomechanical environment of cancer tissue -- 2.3.2 Lymphangiogenesis in cancer -- 2.3.3 Interstitial and lymphatic transport in cancer tissue -- 2.3.4 Mechanisms of cancer cell invasion of initial lymphatics -- 2.3.5 The metastatic lymph node -- 2.4 Conclusions and future perspectives -- References -- 3 Mechanisms of lymphatic spread in colon cancer: insights from molecular and genetic studies -- 3.1 Introduction -- 3.2 Mechanisms of the lymphatic system -- 3.2.1 Lymph formation and movement -- 3.3 Tumor microenvironment -- 3.4 Colorectal cancer staging and treatment -- 3.4.1 Colorectal cancer staging -- 3.4.2 Colorectal cancer treatment -- 3.5 Evolutionary mechanisms of lymph node metastasis -- 3.5.1 Linear models -- 3.5.1.1 Model 1 -- 3.5.1.2 Intratumor heterogeneity -- 3.5.1.3 Model 2. , 3.5.1.4 Parallel model -- 3.5.1.5 Model 3 -- 3.6 Molecular markers of colorectal cancer spread -- 3.7 Molecular markers of metastases -- 3.8 Conclusions -- Conflict of interest -- References -- 4 Anatomy and embryology of the lymphatic system of the colon and rectum -- 4.1 Introduction -- 4.2 Embryology of the lymphatic system -- 4.2.1 Molecular mechanisms -- 4.2.2 The lymph sacs -- 4.3 Anatomy of the lymphatic system -- 4.3.1 Lymphatic capillaries -- 4.3.2 Collecting lymphatic vessels and lymph nodes -- 4.3.3 Lymphatic trunks and ducts -- 4.4 Anatomy of the lymphatic system of the colon and rectum -- 4.4.1 Macroscopic anatomy of the colon and rectum -- 4.4.2 Vascularization of the colon and rectum -- 4.4.3 Lymphatic vessel anatomy in the mesocolon -- 4.4.4 Lymphatic vessel anatomy in the mesorectum -- 4.4.5 Lymphatic drainage of the colon and rectum -- 4.4.5.1 Lymphatic drainage of the colon -- 4.4.5.2 Lymphatic drainage of the rectum -- 4.4.5.3 Preaortic and lumbar lymph nodes -- 4.4.5.4 Lumbar and intestinal lymph trunks and the cisterna chyli -- 4.4.5.5 The thoracic duct -- 4.5 Conclusion -- References -- 2 Pathology and Imaging -- 5 Imaging of colorectal nodal disease -- 5.1 Introduction -- 5.2 Staging, segmentation, and endoscopic detection -- 5.2.1 Staging -- 5.2.2 Segmentation and endoscopic detection -- 5.2.2.1 Colorectal polyps segmentation -- 5.2.2.2 Colorectal tumors segmentation -- 5.3 Metastasis classification and prediction -- 5.3.1 Pathological classification -- 5.3.2 Radiological LNM classification -- 5.3.2.1 Metachronous metastasis prediction -- 5.4 Treatment response, recurrence, and survival -- 5.5 Summary and future directions -- References -- 6 Tumor deposits in colorectal cancer -- 6.1 Introduction -- 6.2 Definition of tumor deposits -- 6.3 The origins and biology of tumor deposits -- 6.3.1 Where do tumor deposits come from?. , 6.3.2 The biological mechanisms underlying tumor deposit development -- 6.4 Staging of tumor deposits -- 6.5 Prognostic value of tumor deposits -- 6.6 Tumor deposits and neoadjuvant therapies -- 6.7 Pathological assessment of tumor deposits: interobserver variation -- 6.7.1 Interobserver agreement regarding tumor deposits in previous TNM editions -- 6.7.2 Interobserver agreement regarding tumor deposits in the TNM 8th edition -- 6.7.3 How to improve interobserver variation regarding tumor deposits? -- 6.8 Radiological assessment of tumor deposits: advances and challenges -- 6.8.1 Tumor deposits in colon cancer, identification by CT -- 6.8.2 Tumor deposits in rectal cancer, identification by MRI -- 6.8.3 A radiological concept regarding the origin of tumor deposits -- 6.8.4 The future of tumor deposits in radiology -- References -- 7 Lymph node classification in colorectal cancer: tumor node metastasis versus the Japanese system -- 7.1 Japanese D3 lymphadenectomy -- 7.1.1 Japanese lymph node classification -- 7.1.2 Concept of Japanese lymphadenectomy -- 7.1.3 Lateral lymph node dissection -- 7.1.4 Japanese D3 versus complete mesocolic excision -- 7.2 Tumor node metastasis versus Japanese lymph node classification -- 7.3 Conclusion -- References -- 8 Detection and significance of micrometastases and isolated tumor cells in lymph nodes of colorectal cancer resections -- 8.1 Definition of micrometastases and isolated tumor cells -- 8.1.1 AJCC/UICC definition -- 8.1.2 Methods of detection -- 8.1.3 Biological significance -- 8.1.4 Reporting -- 8.1.5 Summary -- 8.2 Micrometastases and isolated tumor cells in colorectal cancer -- 8.2.1 Implications in colorectal cancer -- 8.2.2 Occult disease in lymph nodes in colorectal cancer -- 8.2.3 Recommendations for standardized histopathological analysis of lymph nodes. , 8.3 Micrometastases and isolated tumor cells in sentinel lymph-node biopsy in colorectal cancer -- 8.3.1 Sentinel lymph-node mapping with ultra-staging -- 8.3.2 Sentinel lymph-node biopsy in colorectal cancer -- 8.4 Micrometastases and isolated tumor cells after neoadjuvant therapy -- 8.5 Differential diagnosis of micrometastases and isolated tumor cells -- 8.6 Conclusion -- References -- 9 Anatomical and temporal patterns of lymph node metastasis in colorectal cancer -- 9.1 Introduction -- 9.2 Mechanisms of lymphatic spread in colon cancer -- 9.3 Temporal patterns of metastasis in colon cancer -- 9.3.1 Evidence from circulating and tissue biomarkers -- 9.3.2 Evidence from genomic and phylogenetic studies -- 9.3.3 Evidence from growth rate of primary and metastatic colorectal tumors -- 9.3.4 Evidence from autopsy findings in metastatic colorectal cancer -- 9.3.5 Evidence from clinical studies -- 9.3.5.1 Segmental resection versus hemicolectomy -- 9.3.5.2 Extra-mesenteric lymph node dissection -- 9.3.5.3 Central (apical) lymph node resection -- 9.3.5.4 High versus low ligation of the inferior mesenteric artery -- 9.3.5.5 Complete mesocolic excision and D3 dissection versus standard resection -- 9.3.5.6 Effect of extended lymphadenectomy on isolated lymph node recurrence -- 9.3.5.7 Lymph node counts and outcome -- 9.4 Anatomical patterns of lymph node metastasis in colon cancer -- 9.5 Conclusion and implications for research -- References -- 3 Treatment -- 10 Neoadjuvant treatment and lymph node metastasis in rectal cancer -- 10.1 Introduction -- 10.2 Importance of lymph node yield -- 10.3 Lymph node yield -- 10.4 Neoadjuvant therapy and lymph node yield -- 10.5 Lymph node ratio -- 10.6 Impact of nodal involvement with complete clinical response after neoadjuvant therapy -- 10.7 Effects of total neoadjuvant therapy -- 10.8 Conclusion -- References. , Further reading -- 11 Complete mesocolic excision in colon cancer -- 11.1 Introduction -- 11.2 Outline of the key anatomy -- 11.3 Principles of CME surgery -- 11.3.1 Role of minimally invasive CME surgery -- 11.4 Oncological benefits of CME -- 11.4.1 Which patients benefit from CME? -- 11.5 Potential limitations of CME and associated controversies -- 11.5.1 Complications -- 11.5.2 Technical difficulties -- 11.5.3 CME in transverse colon cancer -- 11.6 Importance of pathological quality control in CME surgery -- 11.6.1 Integrity of the mesocolon (plane of surgery) -- 11.6.2 Distance between the tumor and the central arterial ligation point -- 11.6.3 Length of bowel resected -- 11.6.4 Lymph node yield -- 11.6.5 Specimen photography -- 11.7 Conclusion -- References -- 12 Japanese D3 dissection in cancer of the colon: technique and results -- 12.1 Introduction -- 12.2 History of lymphadenectomy for colon cancer in Japan -- 12.2.1 Japanese classification and Japanese guidelines -- 12.3 Basic principles of lymph node dissection in Japan -- 12.4 Changes in the recommended area of lymph node dissection in Japan -- 12.5 Current classifications of lymph node metastasis (N) and lymph node dissection (D) in Japan -- 12.5.1 Basic principles of regional lymph node classification -- 12.6 Lymph node groups and station numbers -- 12.7 Classification of lymph node metastases (N) -- 12.8 Classification of lymph node dissection (D) -- 12.9 Technique of Japanese D3 dissection for colon cancer -- 12.10 Cecum cancer -- 12.11 Ascending colon cancer -- 12.12 Transverse colon cancer -- 12.13 Descending colon cancer -- 12.14 Sigmoid colon cancer -- 12.15 Preservation of the LCA for left-sided colon cancer -- 12.16 Outcomes of Japanese D3 dissection for colon cancer -- 12.16.1 D3 lymphadenectomy versus D2 lymphadenectomy. , 12.17 Current recommendations of the Japanese guidelines, 2019.

Additional Edition: ISBN 0-12-824297-3

Language: English

UID:

Format: 1 online resource (564 p.)

Edition: 1st ed. 2007.

ISBN: 1-280-80504-8 , 9786610805044 , 0-387-48993-2

Series Statement: Cancer treatment and research ; v. 134

Content: Recent developments in regional and systemic anticancer therapies have improved the grim outlook of patients with peritoneal carcinomatosis (PC) from ovarian or gastrointestinal origin, leading to a renewed interest in both the underlying mechanisms at the origin of PC and the various therapeutic options. This is the first volume to provide a multidisciplinary approach to peritoneal carcinomatosis encompassing molecular mechanisms, histopathology, regional and systemic cytotoxic therapy, and surgical options. Peritoneal Carcinomatosis: A Multidisciplinary Approach will be of interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC, as well as for basic and translational scientists active in the field of locoregional cancer spread. Numerous illustrations aid the reader throughout in the many facets of this disease. "Peritoneal Carcinomatosis remains a challenging consequence of cancer associated with significant morbidity. This often devastating condition benefits from a multidisciplinary approach to patient care. This text provides a detailed overview of the pathologic entities, biologic considerations and therapeutic approaches as viewed by experts in the field." Steven T. Rosen, M.D. Series Editor.

Note: Description based upon print version of record. , Peritoneal Carcinomatosis: Basic Concepts -- Structure and Function of Mesothelial Cells -- Molecular Biology of Peritoneal Carcinomatosis -- Role of Adhesion Molecules in Locoregional Cancer Spread -- Surgical Trauma, Minimal Residual Disease and Locoregional Cancer Recurrence -- Pseudomyxoma Peritonei Syndrome: Classification of Appendiceal Mucinous Tumours -- The Pathogenesis of Malignant Ascites -- Natural History of Peritoneal Carcinomatosis from Digestive Origin -- The Rationale for Intraperitoneal Heat and Drug Therapy -- Intraperitoneal Drug Therapy: Physical and Biological Principles -- Current Status of Intraperitoneal Antineoplastic Drug Delivery -- The Biologic Rationale of Hyperthermia -- Interactions between Hyperthermia and Cytotoxic Drugs -- Pharmacodynamic Aspects of Intraperitoneal Cytotoxic Therapy -- Cytoreductive Surgery for Peritoneal Carcinomatosis: Techniques and Methods -- Patient Selection for Cytoreduction and Hyperthermic Intraperitoneal Chemoperfusion -- Staging and Scoring of Peritoneal Carcinomatosis -- Peritonectomy Procedures -- Continuous Peritoneal Perfusion: Techniques, Methods and Applications -- Handling of Chemotherapeutic Drugs in the OR: Hazards and Safety Considerations -- Clinical Results of Surgery with or without Intraperitoneal Heated Drug Therapy -- Results of Cytoreduction followed by HIPEC in Carcinomatosis of Colorectal Origin -- HIPEC with Oxaliplatin in the Treatment of Peritoneal Carcinomatosis of Colorectal Origin -- Clinical Results of Cytoreduction and HIPEC in Pseudomyxoma Peritonei -- The Impact of Therapy in the Treatment of Pseudomyxoma Peritonei -- Clinical Results of Cytoreduction and HIPEC for Malignant Peritoneal Mesothelioma -- Cytoreduction and Intraperitoneal Chemotherapy for Carcinomatosis from Gastric Cancer -- Cytoreduction and Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis of Ovarian Cancer -- The role of Neoadjuvant Chemotherapy versus Primary Surgery in the Management of Stage III Ovarian Cancer -- Morbidity and Quality of Life following Cytoreduction and HIPEC -- Detection and Treatment of Recurrent Disease after Cytoreduction and HIPEC -- Nonoperative and Multimodal Management of Peritoneal Carcinomatosis -- Systemic Chemotherapy in Patients with Peritoneal Carcinomatosis from Colorectal Cancer -- Systemic Chemotherapy in patients with Peritoneal Carcinomatosis from Non Colorectal Origin -- The Role of Radiotherapy in the treatment of Peritoneal Carcinomatosis -- Medical and Palliative Management of Malignant Ascites -- Experimental Approaches -- Targeted Intraabdominal Chemotherapy for Peritoneal Carcinomatosis -- Immunotherapy of Peritoneal Carcinomatosis -- Intraperitoneal Photodynamic Therapy -- Intraperitoneal Gene Therapy. , English

Additional Edition: ISBN 0-387-48991-6

Language: English

DOI: 10.1007/978-0-387-48993-3

UID:

Format: 1 online resource (IV, 476 p.) : , 9 Taf.

Edition: Reprint 2020

ISBN: 9783112386200

Series Statement: Archiv für pathologische Anatomie und Physiologie und für klinische Medicin ; Band 214

Note: Frontmatter -- , Inhalt des 214. Bandes. -- , I . Thymusstudien. III. Die Pathologie der Thymus. -- , II. Über die Wirkung des Thymus im Organismus. -- , III. Thymus und Adrenalsystem. -- , IV. Über Karnifikation in tuberkulösen Lungen. -- , y. Über das Vorkommen einer doppeltlichtbrechenden Substanz als normaler Bestandteil der Prostataepithelzelle des Menschen und Farren. -- , VI. Zur Kenntnis der malignen Neuroblastome des N. sympathicus. -- , VII. Zur Histologie der Vinylaminnephritis. -- , VIII. Zur Kenntnis des sogenannten embryonalen Adenosarkom der Niere. -- , IX. Beiträge zur Pathologie der Bauchspeicheldrüse. -- , X. Über die Gehirnkomplikationen des Keuchhustens mit besonderer Berücksichtigung der „Pachymeningitis productiva interna". -- , XI. Beitrag zur Ätiologie des Duodenalgeschwüres (akzessorisches Nebenpankreas, Duodenaldrüsen-adenom und -adenokarzinom). -- , XII. Experimente zur plastischen Aszitesdrainage, zugleich ein Beitrag zur Histologie implantierter Formolgefäße. -- , XIII. Zur Kenntnis der Aneurysmen im Bereich der Arteria hepatica (dissezierendes Aneurysma mit Ausheilung durch totale Thrombose mit sekundärer Verkalkung und Verknöcherung des Thrombus.) -- , XIV. Über eine besondere Form von Entwicklangsstörung der Trikuspidalklappe. -- , XV. Die Herkunft der Plasmazellen. -- , XVI. Über das Vorkommen von Plasmazellen und ihre Bedeutung bei Pneumonieen des Kindesalters nach akuten Infektionskrankheiten. -- , XVII. Über Uterustumoren bei Kaninchen. -- , XVIII. Ein Beitrag zur Ätiologie der Pachymeningitis interna haemorrhagica. -- , XIX. Über Pachymeningitis haemorrhagica interna. -- , XX. Über die Veränderungen der Hypophyse bei der experimentellen Diphtherie. -- , XXI. Das Nervenpigment beim Papagei. -- , XXII. Über Veränderungen der Magenschleimhaut bei Tieren nach Nebennierenexstirpation und über experimentell erzeugte Magengeschwüre. -- , XXIII. Ein Fall von Ulcus ventriculi verursacht durch Schimmelpilze. -- , XXIV. Über die Gastritis polyposa. -- , XXV. Beitrag zur Lehre von der Malakoplakie der Harnblase. -- , XXVI. Beobachtungen über Glykogen in der glatten Muskulatur -- , XXVII. Nachtrag zu unserer Arbeit „Studien über die Histogenese der Lymphdrüsentuberkulose und die Frühstadien des Lymphdrüsentuberkels". , In German.

Additional Edition: ISBN 9783112386194

Language: German

DOI: 10.1515/9783112386200

URL: https://doi.org/10.1515/9783112386200

URL: https://www.degruyter.com/isbn/9783112386200

URL: https://doi.org/10.1515/9783112386200

URL: https://www.degruyter.com/isbn/9783112386200

UID:

Format: 1 online resource (IV, 476 p.) : , 10 Taf.

Edition: Reprint 2020

ISBN: 9783112386583

Series Statement: Archiv für pathologische Anatomie und Physiologie und für klinische Medicin ; Band 207

Note: Frontmatter -- , Inhalt des 207. Bandes -- , Erstes Heft (6. Januar) -- , I. Die normale Involution der Thymus. (Aus dem Laboratorium für Pathologische Anatomie des städtischen Ospedale Maggiore di San Giovanni Battista in Turin.) -- , II. Thymusstudieii. I. Über das Anftreten von Fett in der Thymus. Die pathologische Involution der Thymus -- , III. Eine seltene Komplikation bei Pyonephrose. (Auftreten kugeliger Gerinnungsprodukte im Nierenbecken.) (Aus dem Pathologischen Institut zu Erlangen.) -- , IV. Einige Bemerkungen Uber die Entstehung der angeborenen Zystenniere. (Aus dem Pathologischen Institute der Universität Lemberg.) -- , V. Über den Zusammenhang; von Nebennieren- und Appendixerkrankungen mit schweren Kotstauungen -- , VI. Zur Kenntnis der anatomischen Formen der Typhlatonie -- , VII. Ein Beitrag zur Lehre der Osteogenesis imperfecta. (Aus dem Pathologischen Institute der Universität Straßburg.) -- , VIII. Kurze Bemerkung zur Akromegaliefrage -- , IX. Beitrag zur Aktinomykose des Bauchfells. (Aus dem Pathologischen Institut des städt. Krankenhauses Moabit in Berlin.) -- , X. Über ein metastasierendes Hodenteratom. (Aus dem Pathologischen Institute der Universität Göttingen.) -- , XI. Uber die Veränderungen der Herzmuskulatur, vor allem des Atriorentrikularbündels bei Diphtherie; zugleich ein Beitrag zur Frage der Selbständigkeit des Bündels. (Aus dem Pathologischen Institute der Universität Göttingen.) -- , XII. Ein Fall von Hämophilie beim Binde -- , XIII. Einiges über Wachstum und Virulenz des Erregers der Hühnertuberkulose. (Aus dem Pathologischen Institute der Universität zu Königsberg i. Pr.) -- , XIV. Über Spirochäten und Spirochätosen der oberen Luft- und Verdauungswege1). (Aus der Kgl. Universitäts-Poliklinik für Hals- und Nasenkranke zu Königsberg.) -- , Zweites Heft (7. Februar) -- , XV. Beitrag zur Frage der kompensatorischen Lungenhypertrophie. (Aus dem pathologisch-anatomischen Laboratorium der Universität Groningen.) -- , XVI. Über karzinomatose Entartung eines zystischen Mediastinalteratoms. (Aus dem Pathologischen Institute der Universität Berlin.) -- , XVII. Über Hodenatrophie nach Parotitis epidemica. (Aus dem Pathologisch-anatomischen Institute der Universität Kopenhagen.) -- , XVIII. Die Herkunft der intrakanalikulären Riesenzellen bei der Hoden-Tuberkulose. (Aus dem Pathologisch-anatomischen Institute des städtischen Krankenhauses Moabit-Berlin.) -- , XIX. Ein Fibromyom der Samenblase. (Aus dem Pathologischen Institute der Universität Berlin.) -- , XX. Über die Mitochondria in den Epithelzellen der gewundenen Nierenkanälchen bei der Einwirkung einiger Diuretika (Koffein und Theocin). (Aus dem Histologischen Laboratorium zu Helsingfors.) -- , XXI. Studien uber Nierengefäße bei angeborener Nierendystopie. (Aus dem Pathologisch-anatomischen Institute der Kaiserlichen Militär-Medizinischen Akademie zu St. Petersburg.) -- , XXII. Zur Frage des retrograden Transportes im Pfortadergebiete. (Aus dem Pathologischen Institute der Universität Bonn.) -- , XXIII. Anpassungslehre, Histomechanik und Histochemie. Mit Bemerkungen über die Entwicklung und Formgestaltung der Gelenke. Eine Entgegnung auf W. Roux's Berichtigungen -- , Drittes Heft (5. März) -- , XXIV. Untersuchungen über Pankreashätnorrhagie, Pankreas und Fettgewebsnekrose mit besonderer Berücksichtigung von mikroskopischen Beobachtungen am lebenden Tier. (Aus der Pathologisch-anatomischen Anstalt der Stadt Magdeburg.) -- , XXV. Ein Fall von primärem Endotheliom der Lymphdrüsen -- , XXVI. Multiple Epithellome der Haut, mit Mischgeschwulst [der Parotis. (Aus dem Pathologischen Institute der Universität Utrecht.) -- , XXVII. Zur Kenntnis der Nebennierenzysten. (Aus dem Pathologisch-anatomischen Institute der Universität Lemberg.) -- , XXVIII. Über angeborenen Verschluß des Duodenums -- , XXIX. Eine Bauchfellduplikatur zwischen dem Mesosigmoideum und dem weiblichen Geschlechtsapparat: das „Ligamentum infundibulo-colicum" -- , XXX. Über Pfortadersklerose. (Aus dem Pathologischen Institute des Allgemeinen Krankenhauses St. Georg, Hamburg.) -- , XXXI. Über die autolytische Milchsäurebildung in pathologischer Leber. (Aus der chemischen Abteilung des Pathologischen Institutes der Universität Berlin.) -- , XXXII. Hämatologische Studien (III. Fortsetzung zu Bd. 143 u. 174.) Leukozyten und Leukämie -- , XXXIIII. Über die Entstehung der Corpora amylacea in der Lunge. (Aus dem Pathologischen Institute der Universität Heidelberg.) -- , XXXIY. Über die örtliche Wirkung des Salvarsans bei intraglutäaler Injektion. (Aus dem Pathologischen Institute der Universität Berlin.) -- , XXXV. Über das Verhalten der Leber gegenüber den verschiedenen Arten von Speisefett. Experimentelle Untersuchung. (Aus dem Pathologisch-anatomischen Institut der Kaiserlichen Militär - medizinischen Akademie zu St. Petersburg.) -- , XXXVI. Die Cholesterinesterverfettung (Oholesterinsteatose) der Kupfferschen Sternzellen mit Bemerkungen über deren Verfettung bei Diabetes. (Aus dem Pathologischen Institute der Kaiserlichen Universität zu Tokio.) -- , Literatur -- , Berichtigung , In German.

Additional Edition: ISBN 9783112386576

Language: German

DOI: 10.1515/9783112386583

URL: https://doi.org/10.1515/9783112386583

URL: https://www.degruyter.com/isbn/9783112386583

URL: https://doi.org/10.1515/9783112386583

URL: https://www.degruyter.com/isbn/9783112386583

UID:

Format: 1 online resource (IV, 476 p.) : , 8 Taf.

Edition: Reprint 2020

ISBN: 9783112386606

Series Statement: Archiv für pathologische Anatomie und Physiologie und für klinische Medicin ; Band 211

Note: Frontmatter -- , Inhalt des 211. Bandes -- , Erstes Heft (15. Januar). -- , I. Uber Pankreaavergiftung. (Aus dem Institut für Gerichtliche Medizin der Universität Turin.) (Hierzu 6 Kurven.) -- , II. Über drüsenähnliche Epithelbildungen bei Perikarditis. (Aus dem Pathologischen Institut der Universität Berlin.) (Hierzu 3 Textfiguren.) -- , III. Veränderungen der Arteria iliaca communis bei Syphilitikern. (Aus dem Laboratorium der Syphilidologischen Klinik der Kaiserl. Militär-Medizinischen Akademie zu St. Petersburg.) (Hierzu 3 Textfiguren.) -- , IV. Ober lymphatische Herde in der Schilddrüse. (Aus dem Pathologischen Institut des Allgemeinen Krankenhauses St. Georg in Hamburg.) (Hierzu 6 Textfiguren und 1 Kurve) -- , V. Beobachtungen an Gewebskulturen in Vitro. (Aus dem Department of Pathology, Collegeof Physicians and Surgeons, Columbia University, New York.) (Hierzu 16 Textfiguren.) -- , VI. Beitrag zur' Forschung über Endotheliome der Lymphwege. (R. R. Istituti Clinici di Perfezionamento in Mailand.) (Klinik für Gewerbekrankheiten.) (Hierzu Taf. I und 2 Textfiguren) -- , VII. Zur Kenntnis des Neuroepithelioma gliomatosum. (Aus dem Pathologisch-anatomischen Institute der deutschen Universität in Prag.) (Hierzu 8 Textfiguren.) -- , VIII. Subseröse Adenomyomatose des Dünndarms. (Hierzu 6 Textfiguren.) -- , IX. Zur Kenntnis der Pleurasarkome, (Aus der Pathologischanatomischen Abteilung des Krankenhauses Friedrichstadt-Dresden.) -- , Zweites Heft (15. Februar). -- , X. Zur Kasuistik der epidermoidalen Cholesteatome des Gehirns. (Aus dem Pathologisch-Anatomischen Institut der Universität Charkow.) (Hierzu 1 Textfigur.) -- , XI. Über Riesenzellenbildung in Thyreoidea und Prostata (zugleich ein Beitrag zur Histologie der Fremdkörpertuberkulose.) (Aus dem Pathologischen Institut der Universität Kiel.) (Hierzu 8 Textfiguren.) -- , XII. Uber strahlige Einschlüsse in Riesenzellen -- , XIII. Uber das Endost. (Hierzu 3 Textfiguren und Taf. II.) -- , XIV. Über die Histogenese der Myokardveränderungen bei einigen Intoxikationen. (Aus dem Pathologisch-Anatomischen Institut der Kaiserlichen Militär-Medizinischen Akademie zu St. Petersburg.) (Hierzu Taf. III und 6 Textfiguren.) -- , XV. Über die Atherosklerose der Atrioventrikularklappen. (Aus dem Pathologischen Institut Freiburg i. Br.) (Hierzu Taf. IV und 2 Textfiguren.) -- , XVI. Zur Zystennierenfrage. (Hierzu 4 Textfiguren.) -- , XVII. Über Plasmazellen in den Nieren. (Aus dem Pathologischen Institut der Universität Berlin.) (Hierzu Taf. V, VI.) -- , XVIII. Historische Bemerkung zur Methylgrün-Pyronin- Schnittfärbung -- , XIX. Über eine eigenartige Form knotiger Hyperplasie der Leber, kombiniert mit Gehirnveränderungen. (Aus dem Pathologischen Institut der Universität Göttingen.) (Hierzu 4 Textfiguren.) -- , Drittes Heft (11. März). -- , XX. Über die Bedeutung der Langerhansschen Inseln im menschlichen Pankreas (mit besonderer Berücksichtigung der durch Methylgrün- Pyroninfärbung gewonnenen Resultate). (Aus dem Pathologischen Institut der Universität Berlin.) (Hierzu Taf. VII und 2 Textfiguren.) -- , XXI. Über die pathologische Histologie der syphilitischen Aortitis mit besonderer Berücksichtigung des Vorkommens von Plasmazellen. (Aus dem Pathologischen Institut der Universität Berlin.) (Hierzu Taf. VIII.) -- , XXII. Über einen Fall von Morbus Recklinghausen mit Hypernephrom. (Aus der chirurgischen Abteilung des städtischen Wenzel- Hancke-Krankenhauses in Breslau.) (Hierzu 3 Textfiguren.) -- , XXIII. Ein Fall von Situs viscerum inversus completus. (Aus der Abteilung für innere Krankheiten (I. B.) des St. Lazarus-Landesspitals in Krakau.) (Hierzu 4 Textfiguren.) -- , XXIV. Über angeborenen Relief- und Leistenschädel bei Spina bifida und Enzephalozele. (Aus dem Pathologischen Institut zu Marburg.) (Hierzu 2 Textfiguren.) -- , XXV. Die Mechanik der Embolie -- , XXVI. Zur pathologischen Anatomie des Paratyphus -- , Bemerkung zu dem Aufsatze von Tsiwidis in Bd. 211 S. 43 dieses Archivs , In German.

Additional Edition: ISBN 9783112386590

Language: German

DOI: 10.1515/9783112386606

URL: https://doi.org/10.1515/9783112386606

URL: https://www.degruyter.com/isbn/9783112386606

URL: https://doi.org/10.1515/9783112386606

URL: https://www.degruyter.com/isbn/9783112386606

UID:

Format: 1 online resource (384 p.) : , Mit 1 Tafel und 32 Textfiguren

Edition: Reprint 2021

ISBN: 9783112604168

Series Statement: Archiv für pathologische Anatomie und Physiologie und für klinische Medicin ; Band 219

Note: In German.

Additional Edition: ISBN 9783112604151

Language: German

DOI: 10.1515/9783112604168

URL: https://doi.org/10.1515/9783112604168

URL: https://www.degruyter.com/isbn/9783112604168

URL: https://doi.org/10.1515/9783112604168

URL: https://www.degruyter.com/isbn/9783112604168