UID:
edoccha_9960074552802883
Format:
1 online resource (412 pages)
ISBN:
0-12-815714-3
,
0-12-815713-5
Content:
Handbook of Vascular Motion provides a comprehensive review of the strategies and methods to quantify vascular motion and deformations relevant for cardiovascular device design and mechanical durability evaluation. It also explains the current state of knowledge of vascular beds that are particularly important for the medical device industry. Finally, it explores the application of vascular motion to computational simulations, benchtop testing and fatigue analysis, as well as further implications on clinical outcomes, product development and business.
Note:
Front Cover -- Handbook of Vascular Motion -- Copyright Page -- Dedication -- Contents -- List of Contributors -- Foreword -- Endorsements -- I. Tools for Quantifying Vascular Motion -- 1 Introduction -- Do Blood Vessels Move? -- Absence of Evidence is Not Evidence of Absence -- Importance of Vascular Motion -- 2 Deciding What Vascular Motions You Need -- Function and Accommodation -- Indication and Patient Population -- Cardiac Pulsatility -- Respiration and Valsalva -- Musculoskeletal Influences -- Body Position and Gravity -- Don't Reinvent the Wheel -- Animal Studies -- Cadaver Studies -- Clinical Studies -- Outside Partners -- Conclusion -- Reference -- 3 Medical Imaging Modalities and Protocols -- Medical Imaging Modalities -- X-Ray Transmission -- Acoustic and Light Reflection -- Magnetic Resonance -- Radiation Emission -- Imaging Based on Target -- Imaging Based on Type of Motion -- Imaging Based on Timescale and Periodicity -- Medical Imaging Protocols -- Contrast Injection and Acquisition Timing -- Computed Tomography Imaging Parameters -- Risk/Benefit -- Patient Recruitment and Imaging Challenges -- Conclusion -- References -- 4 Geometric Modeling of Vasculature -- Imaging Processing Software -- Image Format and Viewing -- Image Segmentation and Editing -- Centerline Extraction -- Optimization of Geometric Modeling -- Identifying Branch Vessel Ostia -- Model Coregistration -- Vessel Surface Modeling -- Conclusion -- References -- 5 Quantifying Vascular Deformations -- Defining and Utilizing Fiducial Markers -- Cross-Sectional Deformation -- Axial Length Deformation -- Bending Deformation -- Branch Angle Deformation -- Axial Twist Deformation -- Surface Curvature Deformation -- Conclusion -- References -- II. How the Blood Vessels Move -- 6 Coronary Arteries and Heart -- Coronary ANATOMY -- Coronary Artery Cross-Sectional Deformations.
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Coronary Artery Axial, Bending, Twisting, and Bifurcation Angle Deformations -- Cardiac Anatomy -- Direct Measurement of Myocardial Motion and Deformation -- Myocardial Deformation Estimated From Coronary Artery Motion -- Aortic Valve Motion and Deformation -- Conclusion -- References -- 7 Arteries of the Head and Neck -- Carotid Artery Anatomy -- Carotid Artery Motion from Cardiac Pulsatility -- Carotid Artery Diameter Changes -- Longitudinal Motion of the Carotid Artery -- Carotid Artery Motion from Musculoskeletal Movement with and without Medical Devices -- Vertebrobasilar Artery Anatomy -- Vertebrobasilar Artery Motion from Natural Musculoskeletal Movement -- Vertebrobasilar Artery Motion from Manipulation -- Vertebrobasilar Artery Motion Due to Medical Devices -- Conclusion -- References -- 8 Thoracic Aorta and Supra-Aortic Arch Branches -- Anatomy of Thoracic Aorta -- Thoracic Aorta -- Supra-Aortic Arch Branches -- Geometric Analysis Methods -- Pathologies of the Thoracic Aorta -- Thoracic Aortic Aneurysm -- Aortic Dissection -- Thoracic Aortic Deformations -- Native Thoracic Aortic Deformations -- Morphologic Alterations Due to Thoracic Aortic Endograft Placement -- Deformation Alterations Due to Thoracic Aortic Endograft Placement -- Long-Term Aortic Remodeling -- Pathologies of the Aortic Arch and Supra-Aortic Arch Branches -- Thoracic Outlet Syndrome -- Supra-Aortic Branch Vessel Aneurysm -- Aortic Arch Dissection -- Supra-Aortic Arch Branch Vessel Deformations -- Native Supra-Aortic Arch Branch Vessel Deformations -- Musculoskeletal Influences (Thoracic Outlet Syndrome) -- Morphologic Alterations Due to Thoracic Aortic Endograft Placement -- Conclusion -- References -- 9 Abdominal Aorta and Renovisceral Arteries -- Anatomy of Abdominal Aorta -- Abdominal Aorta -- Renovisceral Arteries -- Geometric Analysis Methods.
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Pathologies of the Abdominal Aorta -- Abdominal Aortic Deformations -- Cardiac Pulsatility Before and After Endograft Placement -- Musculoskeletal Influences -- Long-Term Aortic Remodeling after Endograft Placement -- Pathologies of the Renovisceral Arteries -- Renovisceral Artery Deformations -- Native Renovisceral Artery Motion -- Renovisceral Artery Motion after Complex Endovascular Abdominal Aortic Repair -- Acute and Long-Term Morphologic Alterations Due to Complex Endovascular Abdominal Aortic Repair -- Conclusion -- References -- 10 Lower Extremity Arteries -- Iliac Artery -- Anatomy -- Motion From Pulsatility -- Motion From Musculoskeletal Movement -- Motion From External Influences -- Femoropopliteal Artery -- Anatomy -- Motion from Pulsatility -- Native Artery Deformations from Musculoskeletal Movement -- Stented Artery Deformations from Musculoskeletal Movement -- Cross-Sectional Compression -- Tibial Arteries -- Anatomy -- Tibial Artery Motion -- Conclusion -- References -- 11 Veins of the Upper Body -- Upper Body Venous Anatomy -- Changes in Venous Anatomy With Posture -- Respiration and Its Effects on Venous Caliber -- Pathological Conditions and Venous Devices -- Central Line Movements With Respiration and Postural Change -- Deep Versus Superficial Fixation and the Effects of Body Habitus -- Complications of Device Placement -- Upper Limb Deep Venous Thrombosis -- Challenges of Vascular Access for Renal Replacement Therapies -- Arteriovenous Fistulae -- Arteriovenous Grafts -- Central Venous Catheters -- Conclusion -- References -- 12 Inferior Vena Cava and Lower Extremity Veins -- Veins versus Arteries -- Inferior Vena Cava and Renal Veins -- Anatomy and Pathology -- Inferior Vena Cava Motion with Respiration -- Inferior Vena Cava Motion with Valsalva and Other Influences -- Nutcracker Syndrome -- Iliofemoral Veins.
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Anatomy and Pathology -- Iliac Vein Deformation with Respiration and Valsalva -- Iliac Vein Compression from External Structures -- Iliofemoral Vein Deformation with Hip Joint Movement -- Femoropopliteal Veins -- Anatomy and Pathology -- Common Femoral Vein Deformations with Posture, Respiration, and Calf Contraction -- Femoropopliteal Vein Deformations from Musculoskeletal Influences -- Conclusion -- References -- III. Utilizing Vascular Motion Data and Implications -- 13 Developing Boundary Conditions for Device Design and Durability Evaluation -- Choosing Deformation Metrics -- Sample Statistics -- Defining the Duty Cycle -- Diametric Deformation Example -- Axial Length Deformation Example -- Bending Deformation Example -- Walking -- Stair-Climbing -- Other Deformations and Considerations -- Number and Frequency of Cycles -- Goldilocks Zone -- Conclusion -- References -- 14 Device Design and Computational Simulation -- Since the Dawn of Stent Engineering -- Rapid Change -- The Product Development Process -- The Discovery Cycle -- Inspiration -- Goals and Constraints -- Engineering -- Fabrication -- Design Control and Engineering Specifications -- Simulation -- Finite Element Analysis -- Feasibility Screening -- Prototype and Test -- Conclusion -- References -- 15 Evaluation of Mechanical Fatigue and Durability -- Principles of Fatigue and Durability Assessment -- Cardiovascular Implant Analysis and Testing Methods -- Case Study 1: Balloon-Expandable Stent -- Case Study 2: Nitinol Self-Expanding Stent -- Cardiac Pulse Pressures -- Musculoskeletal and Respiratory Motions -- Case Study 3: Structural Heart Implant Device -- Conclusion -- References -- 16 Clinical Implications of Vascular Motion -- Clinical Consequences of Coronary Stent Fracture -- Clinical Consequences of Lower Extremity Artery Stent Fracture.
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Clinical Consequences of Early Aortic Endograft Failures -- New Endografts: Are We Reliving Past Problems? -- Postimplantation Surveillance for Device Failure -- Example of Endovascular Aneurysm Repair -- Example of Percutaneous Coronary Intervention -- Conclusions on Surveillance Testing for Device Failure -- Conclusion -- References -- 17 Product Development and Business Implications -- The Endurant Evo Experience -- So Close -- Transition Stent Fractures -- Root Cause Investigation -- Lessons Learned -- The TAG Experience -- Need and Expertise Come Together -- TAG 1.0 Design -- Spine Wire Fractures -- Incorrect Early Assumptions -- Improved Testing and Design -- Coordination of R& -- D and Sales Rollout -- Sales Call -- The Responsibility and Burden of R& -- D -- When R& -- D and Sales Meet -- Surprises With Early Endovascular Aortic Repair -- Biomechanical Loading Data Is Critical -- The Path Was Murky in the Early Days -- Lack of Understanding Led to Failures -- Knowledge and Devices Are Improving -- The Future Is Bright -- The Zilver PTX Experience -- The Wild West -- A Measured Approach to Boundary Conditions -- Thorough Mechanical Evaluation -- Improving Stent Performance -- Expand Success -- Stick with What Works -- Improvement without Change -- Conclusion -- References -- 18 Conclusion and Future Directions -- Vasculature Mobility Is Important -- Fractures Do Not Equal Failures -- Vascular Deformations Beyond Mechanical Durability Testing -- Improving Mechanical Durability in a Pinch -- Conclusion -- References -- Acknowledgments -- About the Author -- Index -- Back Cover.
Language:
English
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