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  • 1
    Online Resource
    Online Resource
    Micro-, Meso- and Macro-Dynamics of the Brain (2016)
    Cham :Springer International Publishing :
    Details
    UID:
    almahu_9947389239902882
    Format: XIII, 172 p. 33 illus., 30 illus. in color. , online resource.
    ISBN: 9783319288024
    Series Statement: Research and Perspectives in Neurosciences,
    Content: How does the brain orchestrate perceptions, thoughts, and actions from the activity of its neurons? Addressing these challenging issues requires methods with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks as well as theories to advance understanding how different levels of brain dynamics interact. This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The topics cover the most fascinating facets of neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory and mental illness, brain controlled robots, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Overall, this volume offers an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease. 2FI0208.
    Note: Hippocampal mechanisms for the segmentation of space by goals and boundaries -- Cortical Evolution: Introduction to the Reptilian Cortex -- Flow of information underlying a tactile decision in mice -- The Visual Brain: Computing through Multiscale Complexity -- Grid cells and spatial maps in entorhinal cortex and hippocampus -- The striatum and decision-making based on value -- Decoding the dynamics of conscious perception: The temporal generalization method -- Sleep and synaptic down-selection -- Federating and integrating what we know about the brain at all scales - a challenge for the future. Computer science meets the clinical neurosciences.
    In: Springer eBooks
    Additional Edition: Printed edition: ISBN 9783319288017
    Language: English
    DOI: 10.1007/978-3-319-28802-4
    URL: http://dx.doi.org/10.1007/978-3-319-28802-4
    URL: Volltext  (kostenfrei)
    URL: kostenfrei
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Fulltext
    Stabi Berlin
    HU Berlin
    UB Potsdam
    EUV Frankfurt
    HTW Berlin
    FH Potsdam
    BTU Cottbus
  • 2
    Online Resource
    Online Resource
    Stem Cells in Neuroendocrinology (2016)
    Cham :Springer International Publishing :
    Details
    UID:
    almahu_9947388543702882
    Format: XII, 156 p. 16 illus. in color. , online resource.
    ISBN: 9783319416038
    Series Statement: Research and Perspectives in Endocrine Interactions,
    Content: This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions. .
    Note: A brief overview of techniques for modulating neuroendocrine and other neural systems -- Basics of stem cell biology as applied to the brain -- Human pluripotent-derived lineages for repairing hypopituitarism -- Recapitulating hypothalamus and pituitary development using ES/iPS cells -- Regulation of body weight and metabolism by tanycyte-derived neurogenesis in young adult mice -- Genetic dissection of the neuroendocrine and behavioral responses to stressful challenges -- Pituitary stem cells: quest for hidden functions -- Pituitary stem cells during normal physiology and disease -- Epigenetic mechanisms of pituitary cell fate specification -- Advances in stem cells biology: new approaches to understand depression -- Perspective on stem cells in developmental biology, with special reference to neuroendocrine systems. .
    In: Springer eBooks
    Additional Edition: Printed edition: ISBN 9783319416021
    Language: English
    DOI: 10.1007/978-3-319-41603-8
    URL: http://dx.doi.org/10.1007/978-3-319-41603-8
    URL: Volltext  (kostenfrei)
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    Online Resource
    Fulltext
    HU Berlin
    EUV Frankfurt
    HTW Berlin
    FH Potsdam
    BTU Cottbus
  • 3
    Online Resource
    Online Resource
    Hormones and the Brain (2005)
    Berlin, Heidelberg : Springer Berlin Heidelberg
    Details
    UID:
    gbv_1647312825
    Format: Online-Ressource (XVII, 238 p. 53 illus, online resource)
    ISBN: 9783540269403
    Series Statement: Research and Perspectives in Endocrine Interactions
    Additional Edition: ISBN 9783540213550
    Additional Edition: Druckausg. Hormones and the brain Berlin : Springer, 2005 ISBN 3540213554
    Language: English
    Subjects: Medicine
    RVK:
    YG 3703
    Keywords: Hirnfunktion ; Steroidhormon ; Nervendegeneration ; Steroidhormon ; Aufsatzsammlung
    DOI: 10.1007/b138340
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Author information: Gaillard, Rolf C.
    Author information: Christen, Yves 1948-
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    Stabi Berlin
    UB Potsdam
    MPI Bildungsforschung
  • 4
    Online Resource
    Online Resource
    Micro-, Meso- and Macro-Connectomics of the Brain (2016)
    Cham :Springer International Publishing :
    Details
    UID:
    almahu_9947389241302882
    Format: X, 166 p. 32 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2016.
    ISBN: 9783319277776
    Series Statement: Research and Perspectives in Neurosciences,
    Content: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
    Note: Parcellations and connectivity patterns in human and macaque cerebral cortex -- Nanoconnectomics -- Inhibitory cell cypes, circuits and receptive fields in mouse visual cortex -- Form meets function in the brain: observing the activity and structure of specific neural connections -- The network for intracortical communication in mouse visual cortex -- The brain in space -- In-vivo connectivity in monkeys -- Connectome networks: from cells to systems -- Intra- and Inter-hemispheric connectivity supporting hemispheric specialization -- Genetics of the connectome and the ENIGMA project.
    In: Springer eBooks
    Additional Edition: Printed edition: ISBN 9783319277769
    Language: English
    DOI: 10.1007/978-3-319-27777-6
    URL: http://dx.doi.org/10.1007/978-3-319-27777-6
    URL: Volltext  (kostenfrei)
    URL: Inhaltsverzeichnis
    URL: Abstract
    URL: Buchcover
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    Fulltext
    HU Berlin
    HTW Berlin
    BTU Cottbus
  • 5
    Online Resource
    Online Resource
    Hormones and social behaviour (2008)
    Berlin : Springer
    Details
    UID:
    gbv_1647773911
    Format: 1 Online-Ressource (XII, 199 Seiten) , Illustrationen
    ISBN: 9783540792888
    Series Statement: Research and perspectives in endocrine interactions
    Additional Edition: ISBN 9783540792864
    Additional Edition: Buchausg. u.d.T. Hormones and social behavior Berlin : Springer, 2008 ISBN 3540792864
    Additional Edition: ISBN 9783540792864
    Language: English
    Subjects: Biology , Medicine
    RVK:
    YG 3703
    RVK:
    WW 6400
    Keywords: Neuroendokrinologie ; Sozialverhalten ; Aufsatzsammlung
    DOI: 10.1007/978-3-540-79288-8
    URL: Volltext
    URL: Volltext
    URL: Volltext
    URL: Volltext
    URL: Cover
    URL: Kapitel 1
    URL: Inhaltsverzeichnis
    Author information: Christen, Yves 1948-
    Author information: Pfaff, Donald W. 1939-
    Library Location Call Number Volume/Issue/Year Availability
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    Online Access
    Open Access Request
    Stabi Berlin
    UB Potsdam
    MPI Bildungsforschung
  • 6
    Online Resource
    Online Resource
    Micro-, Meso- and Macro-Connectomics of the Brain / (2016)
    Cham : Springer Nature | Cham :Springer International Publishing :
    Details
    UID:
    almahu_9947382415302882
    Format: 1 online resource (X, 166 p. 32 illus., 28 illus. in color.)
    Edition: 1st ed. 2016.
    ISBN: 3-319-27777-4
    Series Statement: Research and Perspectives in Neurosciences,
    Content: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
    Note: Bibliographic Level Mode of Issuance: Monograph , Parcellations and connectivity patterns in human and macaque cerebral cortex -- Nanoconnectomics -- Inhibitory cell cypes, circuits and receptive fields in mouse visual cortex -- Form meets function in the brain: observing the activity and structure of specific neural connections -- The network for intracortical communication in mouse visual cortex -- The brain in space -- In-vivo connectivity in monkeys -- Connectome networks: from cells to systems -- Intra- and Inter-hemispheric connectivity supporting hemispheric specialization -- Genetics of the connectome and the ENIGMA project. , English
    Additional Edition: ISBN 3-319-27776-6
    Language: English
    DOI: 10.1007/978-3-319-27777-6
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    Online Resource
    Open Access Request
    HU Berlin
    FU Berlin
    Charité
  • 7
    Online Resource
    Online Resource
    A Time for Metabolism and Hormones / (2016)
    Cham | Cham :Springer International Publishing :
    Details
    UID:
    almahu_9949736997202882
    Format: 1 online resource (XIII, 132 p. 28 illus., 26 illus. in color.)
    Edition: 1st ed. 2016.
    ISBN: 3-319-27069-9
    Series Statement: Research and Perspectives in Endocrine Interactions,
    Content: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
    Note: Bibliographic Level Mode of Issuance: Monograph , The Epigenetic And Metabolic Language Of the Circadian Clock -- Molecular Architecture of the Circadian Clock in Mammals -- Circadian Mechanisms in Bioenergetics and Cell Metabolism -- Control of metabolism by central and peripheral clocks in Drosophila -- Circadian post-transcriptional control of metabolism -- Redox and Metabolic Oscillations in the Clockwork -- Rev-erbs: Integrating Metabolism Around the Clock -- Control of sleep-wake cycles in Drosophila -- Circadian metabolomics: insights for biology and medicine -- Rhythms within rhythms: the importance of oscillations for glucocorticoid hormones -- The genetics of autism spectrum disorders. . , English
    Additional Edition: ISBN 3-319-27068-0
    Language: English
    DOI: 10.1007/978-3-319-27069-2
    Library Location Call Number Volume/Issue/Year Availability
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    HU Berlin
    FU Berlin
    Charité
  • 8
    Online Resource
    Online Resource
    Micro-, Meso- and Macro-Dynamics of the Brain / (2016)
    Cham : Springer Nature | Cham :Springer International Publishing :
    Details
    UID:
    almahu_9947382415202882
    Format: 1 online resource (XIII, 172 p. 33 illus., 30 illus. in color.)
    Edition: 1st ed. 2016.
    ISBN: 3-319-28802-4
    Series Statement: Research and Perspectives in Neurosciences,
    Content: How does the brain orchestrate perceptions, thoughts, and actions from the activity of its neurons? Addressing these challenging issues requires methods with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks as well as theories to advance understanding how different levels of brain dynamics interact. This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The topics cover the most fascinating facets of neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory and mental illness, brain controlled robots, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Overall, this volume offers an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease. 2FI0208.
    Note: Hippocampal mechanisms for the segmentation of space by goals and boundaries -- Cortical Evolution: Introduction to the Reptilian Cortex -- Flow of information underlying a tactile decision in mice -- The Visual Brain: Computing through Multiscale Complexity -- Grid cells and spatial maps in entorhinal cortex and hippocampus -- The striatum and decision-making based on value -- Decoding the dynamics of conscious perception: The temporal generalization method -- Sleep and synaptic down-selection -- Federating and integrating what we know about the brain at all scales - a challenge for the future. Computer science meets the clinical neurosciences. , English
    Additional Edition: ISBN 3-319-28801-6
    Language: English
    DOI: 10.1007/978-3-319-28802-4
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
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    HU Berlin
    FU Berlin
    Charité
  • 9
    Online Resource
    Online Resource
    Micro-, Meso- and Macro-Connectomics of the Brain. (2016)
    Cham :Springer International Publishing AG,
    Details
    UID:
    almahu_9949602145502882
    Format: 1 online resource (173 pages)
    Edition: 1st ed.
    ISBN: 9783319277776
    Series Statement: Research and Perspectives in Neurosciences Series
    Note: Intro -- Acknowledgments -- Contents -- List of Contributors -- Nanoconnectomics -- Nanoconnectomics -- Extracellular Space -- Simulating Signaling in Small Spaces -- Precision of Synaptic Plasticity -- References -- Inhibitory Cell Types, Circuits and Receptive Fields in Mouse Visual Cortex -- Differences in Connectivity, Visual Responses and Functional Impact of PV Versus SST Interneurons -- Calretinin (CR) and VIP-Expressing Interneurons Target SST Interneurons -- Functional Impact of VIP Interneurons -- References -- Form Meets Function in the Brain: Observing the Activity and Structure of Specific Neural Connections -- Introduction -- CLARITY -- Clarifying Large Tissue Volumes -- CLARITY-Optimized Light Sheet Microscopy -- Tracking Activity in Deep Genetically Targeted Neurons of Behaving Animals -- Neural Activity that Encodes and Predicts Social Interaction -- Outlook -- References -- The Network for Intracortical Communication in Mouse Visual Cortex -- Introduction -- Thalamocortical Projections to Mouse Visual Cortex -- Cortical Cartography -- Areal Organization of Visual Cortex -- Interareal Connections -- Cortical Hierarchy -- Synaptic Organization of Feedforward and Feedback Connections -- Dorsal and Ventral Processing Streams -- References -- The Brain in Space -- Introduction -- The Promise of Network Theory -- Empirical Evidence for a Principled Model of Cortical Connectivity: The EDR Model -- The Cortical Core-Periphery Structure -- Biology, Clustering and the Importance of Weak Links -- Conclusion and Perspectives -- References -- In-Vivo Connectivity in Monkeys -- Anatomical, Functional and Effective Connectivity in Animal Models -- Towards Causality: Effective Connectivity with Focal Perturbation Tools -- Effective Connectivity: Combined Electrical Microstimulation and Whole-Brain fMRI. , Novel Genetically-Based Perturbation Methods? -- References -- Parcellations and Connectivity Patterns in Human and Macaque Cerebral Cortex -- Introduction -- Cortical Cartography and Parcellation -- Distributed Cortical Connectivity -- Interspecies Registration -- Concluding Comments -- References -- Connectome Networks: From Cells to Systems -- Defining the Connectome -- Brain Networks and Graph Theory -- Topology of Structural Brain Networks -- Microscale -- Mesoscale -- Macroscale -- Comparison Across Scales and Challenges -- Relations Between Structure and Function -- Microscale -- Mesoscale -- Macroscale -- Comparison Across Scales and Challenges -- Future Perspectives -- References -- Intra- and Inter-hemispheric Connectivity Supporting Hemispheric Specialization -- Introduction -- Human Dualism: Two Hands, Two Brains -- Asymmetries Measured with Brain Imaging -- Anatomo-Functional Support of HS -- Gray Matter Macroscopic Asymmetries and HS -- White Matter Connections Supporting HS -- Corpus Callosum -- Intra-hemispheric Structural Connectivity -- Functional Asymmetries and Hemispheric Dominance for Language Assessed with Meta-analysis -- Developmental Course of the Setting Up of Anatomical and Functional Asymmetries -- HS, Cognitive Abilities and Developmental/Psychiatric Diseases -- Cognitive Skills and Asymmetries -- Language HS, Developmental and Psychiatric Diseases -- Inter-individual Variability in HS: Factors at Play -- BILandGIN: A Multimodal Database for Investigating HS -- Conclusion -- References -- Genetics of the Connectome and the ENIGMA Project -- Background to ENIGMA -- Genetic Influences on the Brain -- Finding the Genes Involved -- GWAS of the Brain -- Counterarguments and Power -- Non-biological Information Arising from ENIGMA -- But Do the ENIGMA Genes Affect Disease Risk? -- Searching Brain Images for Statistical Effects. , Brain-Wide Genome-Wide Scanning -- Genetic Screening of the Connectome -- Caveats for Multi-site Genomic Analysis of the Connectome -- Future Directions: Adaptive Connectomics and EPIC -- References -- Index.
    Additional Edition: Print version: Kennedy, Henry Micro-, Meso- and Macro-Connectomics of the Brain Cham : Springer International Publishing AG,c2016 ISBN 9783319277769
    Language: English
    Keywords: Electronic books.
    URL: Click to View
    URL: kostenfrei
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  • 10
    Online Resource
    Online Resource
    A Time for Metabolism and Hormones. (2016)
    Cham :Springer International Publishing AG,
    Details
    UID:
    almahu_9949602163002882
    Format: 1 online resource (141 pages)
    Edition: 1st ed.
    ISBN: 9783319270692
    Series Statement: Research and Perspectives in Endocrine Interactions Series
    Note: Intro -- Preface -- Acknowledgements -- Contents -- List of Contributors -- The Epigenetic and Metabolic Language of the Circadian Clock -- Introduction -- Chromatin Remodeling, Cyclic Transcription and the Clock -- Cellular Metabolism and the Circadian Clock Converge -- The Central Role of Sirtuins -- Conclusion -- References -- Molecular Architecture of the Circadian Clock in Mammals -- Introduction -- Structural Biology of Clock Proteins -- Transcriptional Architecture and Chromatin Dynamics of the Clock -- References -- Circadian Mechanisms in Bioenergetics and Cell Metabolism -- Genetic Approaches to Dissecting Circadian Physiology -- Clock-NAD+-Sirtuin Pathway in Bioenergetics -- Reciprocal Control of the Clock by Nutrient -- Summary and Future Directions -- References -- Control of Metabolism by Central and Peripheral Clocks in Drosophila -- Use of Drosophila to Study Behavior and Metabolic Function -- The Drosophila Fat Body Contains a Clock that Regulates a Rhythm of Feeding -- Fat Body and Neuronal Clocks Coordinately Regulate Metabolic Parameters -- Rhythmic Gene Expression in the Fat Body Is Controlled Largely, but not Exclusively, by the Fat Body Clock -- A Restricted Feeding Paradigm Resets the Phase of Cyclic Gene Expression in the Fat Body but not in the Brain -- Decoupling Peripheral and Brain Tissues Decreases Reproductive Fitness -- Metabolic Signals Also Affect Clocks in the Brain -- References -- Circadian Post-transcriptional Control of Metabolism -- Introduction -- Post-transcriptional Mechanisms -- Circadian Control of poly(A) Tail Length -- Nocturnin Is a Circadian Deadenylase -- Loss of Nocturnin Results in Broad Metabolic Changes -- Conclusions -- References -- Redox and Metabolic Oscillations in the Clockwork -- Introduction -- Challenging Transcriptional Models of the Clockwork -- Non-transcriptional Clock Mechanisms. , PRDX Rhythms -- Redox and Metabolic Clocks in Eukaryotes -- Conclusion -- References -- Rev-erbs: Integrating Metabolism Around the Clock -- Introduction -- Repression of Transcription by Rev-erbs -- Circadian Biology of Rev-erbs -- Rev-erbα and Metabolism -- Conclusions -- References -- Control of Sleep-Wake Cycles in Drosophila -- Background -- Layout of the Network in Constant Conditions -- Network Architecture Under LD Cycles -- References -- Circadian Metabolomics: Insights for Biology and Medicine -- Introduction: A Many-Clock Problem -- An Overview of Circadian Metabolomics -- Metabolomics: Applications for Circadian Medicine -- Outlook and Conclusion -- References -- Rhythms Within Rhythms: The Importance of Oscillations for Glucocorticoid Hormones -- Introduction -- The Origin of HPA Pulsatility -- Implications of HPA Pulsatility -- Adrenal Adaptation to Pulsatile ACTH -- Tissue Adaptation to Pulsatile CORT -- Conclusion -- References -- The Genetics of Autism Spectrum Disorders -- Introduction -- Twin and Family Studies in ASD -- From Chromosomal Rearrangements to Copy Number Variants in ASD -- From Candidate Genes to Whole Exome/Genome Sequencing Studies in ASD -- The Common Variants in ASD -- The Genetic Architecture of ASD -- The Biological Pathways Associated with ASD -- The Serotonin-NAS-Melatonin Pathway -- Perspectives -- References -- Index.
    Additional Edition: Print version: Sassone-Corsi, Paolo A Time for Metabolism and Hormones Cham : Springer International Publishing AG,c2016 ISBN 9783319270685
    Language: English
    Keywords: Electronic books.
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