Format:
Online-Ressource (xi, 486 p)
,
ill. (some col.)
,
28 cm
Edition:
1st ed
Edition:
Online-Ausg. Amsterdam Elsevier Science & Technology 2010 Elsevier e-book collection - Neuroscience Electronic reproduction; Mode of access: World Wide Web
ISBN:
1282769022
,
9781282769021
,
9780123748829
Series Statement:
Elsevier science & technology books
Content:
This book provides a grounded introduction to the fundamental concepts of mathematics, neuroscience and their combined use, thus providing the reader with a springboard to cutting-edge research topics and fostering a tighter integration of mathematics and neuroscience for future generations of students. The book alternates between mathematical chapters, introducing important concepts and numerical methods, and neurobiological chapters, applying these concepts and methods to specific topics. It covers topics ranging from classical cellular biophysics and proceeding up to systems level neuroscience. Starting at an introductory mathematical level, presuming no more than calculus through elementary differential equations, the level will build up as increasingly complex techniques are introduced and combined with earlier ones. Each chapter includes a comprehensive series of exercises with solutions, taken from the set developed by the authors in their course lectures. MATLAB code is included for each computational figure, to allow the reader to reproduce them. Biographical notes referring the reader to more specialized literature and additional mathematical material that may be needed either to deepen the reader's understanding or to introduce basic concepts for less mathematically inclined readers completes each chapter. A very didactic and systematic introduction to mathematical concepts of importance for the analysis of data and the formulation of concepts based on experimental data in neuroscience Provides introductions to linear algebra, ordinary and partial differential equations, Fourier transforms, probabilities and stochastic processes Introduces numerical methods used to implement algorithms related to each mathematical concept Illustrates numerical methods by applying them to specific topics in neuroscience, including Hodgkin-Huxley equations, probabilities to describe stochastic release, stochastic processes to describe noise in neurons, Fourier transforms to describe the receptive fields of visual neurons Provides implementation examples in MATLAB code, also included for download on the accompanying support website (which will be updated with additional code and in line with major MATLAB releases) Allows the mathematical novice to analyze their results in more sophisticated ways, and consider them in a broader theoretical framework
Content:
This book provides a grounded introduction to the fundamental concepts of mathematics, neuroscience and their combined use, thus providing the reader with a springboard to cutting-edge research topics and fostering a tighter integration of mathematics and neuroscience for future generations of students. The book alternates between mathematical chapters, introducing important concepts and numerical methods, and neurobiological chapters, applying these concepts and methods to specific topics. It covers topics ranging from classical cellular biophysics and proceeding up to systems level neuroscience. Starting at an introductory mathematical level, presuming no more than calculus through elementary differential equations, the level will build up as increasingly complex techniques are introduced and combined with earlier ones. Each chapter includes a comprehensive series of exercises with solutions, taken from the set developed by the authors in their course lectures. MATLAB code is included for each computational figure, to allow the reader to reproduce them. Biographical notes referring the reader to more specialized literature and additional mathematical material that may be needed either to deepen the reader's understanding or to introduce basic concepts for less mathematically inclined readers completes each chapter. A very didactic and systematic introduction to mathematical concepts of importance for the analysis of data and the formulation of concepts based on experimental data in neuroscienceProvides introductions to linear algebra, ordinary and partial differential equations, Fourier transforms, probabilities and stochastic processesIntroduces numerical methods used to implement algorithms related to each mathematical conceptIllustrates numerical methods by applying them to specific topics in neuroscience, including Hodgkin-Huxley equations, probabilities to describe stochastic release, stochastic processes to describe noise in neurons, Fourier transforms to describe the receptive fields of visual neuronsProvides implementation examples in MATLAB code, also included for download on the accompanying support website (which will be updated with additional code and in line with major MATLAB releases)Allows the mathematical novice to analyze their results in more sophisticated ways, and consider them in a broader theoretical framework
Note:
Includes bibliographical references (p. 473-482) and index
,
Front cover; Mathematics for Neuroscientists; Copyright page; Full Contents; Preface; Chapter 1. Introduction; 1.1. How to Use This Book; 1.2. Brain Facts Brief; 1.3. Mathematical Preliminaries; 1.4. Units; 1.5. Sources; Chapter 2. The Passive Isopotential Cell; 2.1. Introduction; 2.2. The Nernst Potential; 2.3. Membrane Conductance; 2.4. Membrane Capacitance and Current Balance; 2.5. Synaptic Conductance; 2.6. Summary and Sources; 2.7. Exercises; Chapter 3. Differential Equations; 3.1. Exact Solution; 3.2. Moment Methods*; 3.3. The Laplace Transform*; 3.4. Numerical Methods
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3.5. Synaptic Input3.6. Summary and Sources; 3.7. Exercises; Chapter 4. The Active Isopotential Cell; 4.1. The Delayed Rectifier Potassium Channel; 4.2. The Sodium Channel; 4.3. The Hodgkin-Huxley Equations; 4.4. The Transient Potassium Channel*; 4.5. Summary and Sources; 4.6. Exercises; Chapter 5. The Quasi-Active Isopotential Cell; 5.1. The Quasi-Active Model; 5.2. Numerical Methods; 5.3. Exact Solution via Eigenvector Expansion; 5.4. A Persistent Sodium Current*; 5.5. A Nonspecific Cation Current that is Activated by Hyperpolarization*; 5.6. Summary and Sources; 5.7. Exercises
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Chapter 6. The Passive Cable6.1. The Discrete Passive Cable Equation; 6.2. Exact Solution Via Eigenvector Expansion; 6.3. Numerical Methods; 6.4. The Passive Cable Equation; 6.5. Synaptic Input; 6.6. Summary and Sources; 6.7. Exercises; Chapter 7. Fourier Series and Transforms; 7.1. Fourier Series; 7.2. The Discrete Fourier Transform; 7.3. The Continuous Fourier Transform; 7.4. Reconciling the Discrete and Continuous Fourier Transforms; 7.5. Summary and Sources; 7.6. Exercises; Chapter 8. The Passive Dendritic Tree; 8.1. The Discrete Passive Tree; 8.2. Eigenvector Expansion
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8.3. Numerical Methods8.4. The Passive Dendrite Equation; 8.5. The Equivalent Cylinder*; 8.6. Branched Eigenfunctions*; 8.7. Summary and Sources; 8.8. Exercises; Chapter 9. The Active Dendritic Tree; 9.1. The Active Uniform Cable; 9.2. On the Interaction of Active Uniform Cables*; 9.3. The Active Nonuniform Cable; 9.4. The Quasi-Active Cable*; 9.5. The Active Dendritic Tree; 9.6. Summary and Sources; 9.7. Exercises; Chapter 10. Reduced Single Neuron Models; 10.1. The Leaky Integrate-and-Fire Neuron; 10.2. Bursting Neurons; 10.3. Simplified Models of Bursting Neurons; 10.4. Summary and Sources
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10.5. ExercisesChapter 11. Probability and Random Variables; 11.1. Events and Random Variables; 11.2. Binomial Random Variables; 11.3. Poisson Random Variables; 11.4. Gaussian Random Variables; 11.5. Cumulative Distribution Functions; 11.6. Conditional Probabilities*; 11.7. Sum of Independent Random Variables*; 11.8. Transformation of Random Variables*; 11.9. Random Vectors*; 11.10. Exponential and Gamma Distributed Random Variables; 11.11. The Homogeneous Poisson Process; 11.12. Summary and Sources; 11.13. Exercises; Chapter 12. Synaptic Transmission and Quantal Release
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12.1. Basic Synaptic Structure and Physiology
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Electronic reproduction; Mode of access: World Wide Web
Additional Edition:
ISBN 9780080890494
Additional Edition:
ISBN 9780123748829
Additional Edition:
ISBN 1282768972
Additional Edition:
Erscheint auch als Druck-Ausgabe Mathematics for Neuroscientists
Language:
English
URL:
Volltext
(An electronic book accessible through the World Wide Web; click for information)
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