Format:
Online-Ressource (XIII, 354 p. 24 illus., 17 illus. in color, digital)
ISBN:
9783642365607
Series Statement:
Current Topics in Microbiology and Immunology 358
Content:
Microbes colonize nearly every biotic and abiotic niche on our planet. This also includes our human body, which is densely populated with microbes, the majority of which interact with us in a commensal, sometimes even mutualistic, relationship. Only a minority of our microbiota are pathogenic organisms with the ability to cause infection.This book covers various aspects of the interplay between commensal and pathogenic bacteria with their hosts. The chapters summarize recent findings on the geno- and phenotypic traits of opportunistic bacterial pathogens, such as Escherichia coli, staphylococci or Pseudomonas aeruginosa, as well as the impact of commensal and probiotic bacteria on intestinal physiology and health. The differential interaction of pathogenic, commensal and probiotic bacteria with their host is reviewed from both the bacterial and the host’s perspective to round out this compilation of articles on the differences and similarities of pathogenic and commensal microorganisms
Note:
Includes index
,
Preface; Contents; Contributors; Part I Between Commensalism and Pathogenicity: Bacterial and Host Aspects; 303 E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity; Abstract; 1…E. coli: A Versatile Species; 2…Population Genetics of E. coli; 3…Genome Plasticity: The Key to Diversity; 3.1 Mobile Elements and Their Role in E. coli Evolution; 3.2 Genome Content and Phenotypic Variation; 3.3 Genome Plasticity and Evolution of Pathogenic E. coli; 4…Genomic Differences Between ExPEC and Commensal E. coli
,
4.1 ExPEC Virulence or Fitness Traits: A Matter of Perspective, Niche or Strain Background4.2 Impact of Genome Plasticity on Pathogenicity and Fitness of E. coli B2 Strains: Three Closely Related Strains with Markedly Divergent Phenotypes; 5…Outlook on Future E. coli Genomic Studies, Challenges, and What Can Be Expected; Acknowledgments; References; 286 What Distinguishes Highly Pathogenic Staphylococci from Medium- and Non-pathogenic?; Abstract; 1…Introduction; 2…Graduation of Pathogenicity in Staphylococcal Species; 2.1 Highly Pathogenic Staphylococci; 2.2 Medium-pathogenic Staphylococci
,
2.3 Non-pathogenic Staphylococci3…Virulence Factors of Highly and Medium-pathogenic Staphylococci; 3.1 Colonization Factors; 3.1.1 Host Matrix Binding Proteins; 3.1.2 SERAMS and Anchorless Adhesins; 3.1.3 Autolysins/Adhesins; 3.1.4 Elastin-Binding Proteins; 3.1.5 Fibronectin-Binding Proteins; 3.1.6 Factors Involved in Intercellular Adhesion During Biofilm Formation; 3.2 Biofilms; 3.3 Immune Escape and Modulating Factors; 3.3.1 Cytolytic Toxins Interfering with the Immune Response; 3.4 Internalization; 3.5 Toxins---Aggressive Pathogenicity Factors with Host Cell Damaging Activity
,
3.5.1 Toxins in Non-Staphylococcus aureus Species4…Fitness Factors Involved in Infection; 4.1 Exoenzymes; 4.1.1 Nuclease; 4.1.2 Protease; 4.1.3 Lipase; 4.2 Iron Acquisition; 4.3 ACME; 4.4 Urease of Staphylococcus saprophyticus; 4.5 d-Serine Deaminase of Staphylococcus saprophyticus; 5…Physiological Properties Involved in Virulence and Fitness; 5.1 Cyanide-sensitive Cytochrome bd Oxidase Prevalent in Pathogenic Species; 5.2 Small-Colony Variants as a Survival Strategy Under Certain Selective Pressure; 5.3 Structural Alteration of Peptidoglycan and Resistance to Lysozyme; 5.4 Staphyloxanthin
,
6…Antibiotic Resistances7…Regulation of Virulence Determinants; 8…Genomic Aspects Concerning Staphylococcal Virulence; 8.1 Genome Structure; 8.2 Genome Rearrangements; 8.3 Mobile Genetic Elements in Staphylococcus; 8.3.1 Pathogenicity Islands; 8.3.2 Genomic Islands; 8.3.3 Prophages; 8.3.4 Staphylococcal Cassette Chromosome; 8.4 Repeat Sequences; 8.5 Single Nucleotide Polymorphisms; 9…The Non-pathogenic Staphylococcus carnosus in Comparison with the Other Staphylococcal Species; 10…Conclusions; 10.1 Staphylococcus Between Commensalism and Pathogenicity; References
,
199 Microevolution of Pseudomonas aeruginosa to a Chronic Pathogen of the Cystic Fibrosis Lung
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Between Commensalism and Pathogenicity:Bacterial and Host Aspects -- E. coli as an all-rounder: The thin line between commensalism and pathogenicity.- What distinguishes non-pathogenic, from medium and highly pathogenic staphylococci? -- Microevolution of Pseudomonas aeruginosa to a chronic pathogen of the cystic fibrosis lung.- Lactobacillus: Host-Microbe Relationships -- Bacterial Moonlighting Proteins and Bacterial Virulence.- Symbionts and pathogens - what is the difference? -- Host-microbe Interaction in the Intestinal Tract -- Ecology and physiology of the intestinal tract -- The gut microflora and its variety of roles in health and disease -- Mammalian intestinal host-microbe relationships -- Contribution of the intestinal microbiota to human health - from birth to 100 years of age.- Subject index. .
Additional Edition:
ISBN 9783642365591
Additional Edition:
Erscheint auch als Druck-Ausgabe Between pathogenicity and commensalism Berlin : Springer, 2013 ISBN 3642365590
Additional Edition:
ISBN 9783642365591
Language:
English
Subjects:
Biology
Keywords:
Mikroflora
;
Symbiose
;
Pathogenität
;
Aufsatzsammlung
DOI:
10.1007/978-3-642-36560-7
URL:
Volltext
(lizenzpflichtig)
Author information:
Dobrindt, Ulrich 1970-
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