UID:
almahu_9948026706002882
Format:
1 online resource (xix, 588 pages) :
,
illustrations (some color)
Edition:
1st ed.
ISBN:
1-280-63391-3
,
1-4237-4289-3
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9786610633913
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0-08-045828-9
Series Statement:
Handbook of chemical neuroanatomy, v. 21
Content:
Dopamine is a major neurotransmitter of the brain involved in the control of movement, emotion, and cognition; disturbance in dopamine function is associated with disorders like Parkinson's disease, schizophrenia and attention deficit hyperactivity disorder. This volume of the Handbook of Chemical Neuroanatomy provides a series of in depth critical reviews of our present understanding of the most important aspects of dopamine's organisation and disturbed function in the animal and human brain.
Note:
front cover; copyright; front matter; List of Contributors; Foreword for the Handbook of Chemical Neuroanatomy; Preface; table of contents; body; 1. The organization and circuits of mesencephalic dopaminergic neurons and the distribution of dopamine receptors in the brain; ABSTRACT 1; INTRODUCTION 1; THE DOPAMINERGIC NEURONS OF THE VENTRAL MIDBRAIN TEGMENTUM; NEUROCHEMICAL FEATURES OF THE MIDBRAIN DOPAMINERGIC CELL GROUPS AND THEIR INPUTS; NEURAL WIRING IN THE BASAL GANGLIA; DOPAMINERGIC INNERVATION OF THE STRIATUM; DOPAMINE MODULATION OF BASAL GANGLIA RELAYS
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THE VENTRAL STRIATUM AND THE MESOLIMBIC SYSTEM; DOPAMINERGIC INNERVATION OF THE THALAMUS AND CEREBRAL CORTEX; DOPAMINE RECEPTORS: INTRODUCTORY REMARKS; D1 RECEPTORS; D2 RECEPTORS; D3 RECEPTORS; D4 RECEPTORS; D1B/5 RECEPTORS; CONCLUDING REMARKS 1; ABBREVIATIONS 1; ACKNOWLEDGMENTS 1; REFERENCES 1; 2. Signal transduction of dopamine receptors; INTRODUCTION 2; HISTORICAL ELEMENTS 2; SIGNAL TRANSDUCTION OF D1-TYPE RECEPTORS; SIGNAL TRANSDUCTION OF D2-TYPE RECEPTORS; REGULATION OF GENE EXPRESSION BY DOPAMINE RECEPTOR SIGNALING; CONCLUSIONS 2; ABBREVIATIONS 2; REFERENCES 2
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3. The use of dopamine receptor knockout mice in understanding brain dopamine neurotransmission and sprouting in the nigrostriatal pathway; ABSTRACT 3; DOPAMINE AND DOPAMINE RECEPTORS IN THE CENTRAL NERVOUS SYSTEM; SPROUTING OF DOPAMINERGIC AXONS; SUMMARY 3; ABBREVIATIONS 3; REFERENCES 3; 4. Structural and functional interactions in the striatum at the receptor level; ABSTRACT 4; CONTEXT 4; THE NATURE OF THE DOPAMINE SIGNAL; PHYSIOLOGICAL EFFECTS OF DOPAMINE; SYNTHESIS AND CONCLUSIONS 4; REFERENCES 4; 5. Motor function(s) of the nigrostriatal dopamine system: studies of lesions and behavior
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ABSTRACT 5; INTRODUCTION: THE CLASSICAL MODELS; SPONTANEOUS MOTOR EFFECTS OF DOPAMINERGIC DRUGS; BILATERAL NIGROSTRIATAL LESIONS IN RATS; UNILATERAL NIGROSTRIATAL LESIONS IN RATS; OTHER TOXIN MODELS; GENETIC MODELS; SUMMARY AND CONCLUSIONS 5; REFERENCES 5; 6. Dopamine, motivation and reward; ABSTRACT 6; INTRODUCTION 6; GENERAL OUTLINE 6; ANATOMICAL BACKGROUND; TERMINOLOGY 6; EXPERIMENTAL STUDIES ON THE ROLE OF DA IN MOTIVATION: METHODOLOGICAL CONSIDERATIONS; IN VIVO, MONITORING OF DOPAMINE FUNCTION: METHODOLOGICAL ISSUES; DRUGS SURROGATES OF NATURAL REWARDS?
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DOPAMINE AND DEPENDENCE THEORIES OF DRUG ADDICTIONNONINCENTIVE ACCOUNTS OF DRUG ADDICTION; DRUG ADDICTION AS ABNORMAL MOTIVATION; A GENERAL THEORY OF ABNORMAL MOTIVATION AS DISADAPTIVE RESPONSIVENESS OF NAC SHELL DA; CONCLUSION 6; ABBREVIATIONS 6; ACKNOWLEDGMENTS 6; REFERENCES 6; 7. Role of cortical and striatal dopamine in cognitive function; ABSTRACT 7; INTRODUCTION 7; A ROLE FOR DA IN LEARNING AND MEMORY; ROLE OF DA IN ATTENTION; WORKING MEMORY; DA AND COGNITION IN HUMANS; CURRENT FOCI AND FUTURE DIRECTIONS; ACKNOWLEDGMENTS 7; REFERENCES 7; 8. Functional neuroanatomy of hypothalamic dopaminergic neuroendocrine systems
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English
Additional Edition:
ISBN 0-444-51778-2
Language:
English
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