Kooperativer Bibliotheksverbund

UID:

Format: 1 Online-Ressource (212 p.) , col., ill., strated inthroughout

ISBN: 1847558909 , 9781847558909

Series Statement: RSC Nanoscience & nanotechnology v. 6

Note: Accessible in style, Nanofluidics fills a gap in the literature for a book focusing on bioanalytical applications within this growing field, In his now celebrated lecture at the 1959 meeting of the American Physical Society, Richard Feynman pondered the potential of miniaturization in the physical sciences. His vision, based on known technology, examined the limits set by physical principles and proposed a variety of new nano-tools including the concept of "atom-by-atom" fabrication. In the intervening decades, many of these predictions have become reality. In particular, the development and application of nanofluidics is becoming a competitive and exciting field of research. These nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency. In a fundamental sense, chip-based analytical systems have been shown to have many advantages over their conventional (larger) analogues. Despite the growth of this field, there are surprisingly few books dedicated to nanofluidics. This book will fill the gap in the literature for a text focusing on bioanalytical applications. Written at a level accessible to experts and non-experts alike, it has the potential to become a mainstream text book for advanced nanobiotechnology courses within academic institutions

Language: English

Subjects: Engineering , Physics

Keywords: Nanostrukturiertes Material ; Nanotechnologie ; Mikrofluidik ; Aufsatzsammlung

URL: Volltext

UID:

Format: 1 online resource (xi, 176 pages) : , illustrations (some color).

ISBN: 1-299-39845-6 , 1-4377-3474-X

Series Statement: Micro & nano technologies series

Content: Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necess

Note: Description based upon print version of record. , Front Cover; Engineered Nanopores for Bioanalytical Applications; Copyright Page; List of Contributors; Contents; Introduction; Engineered nanopores for bioanalytical applications; 1 Ion Transport in Nanopores; 1.1 Introduction; 1.2 Brownian motion; 1.3 Net transport of ions: the Nernst-Planck equation and its derivation; 1.4 The conductance of a pore with uncharged walls; 1.4.1 Cylindrical pores; 1.4.2 Pores with noncylindrical geometries; 1.4.3 Access resistance; 1.5 The effect of surface charge; 1.5.1 Charged surfaces in solution; 1.5.2 The conductance of nanopores with charged inner walls , 1.5.3 The ζ-potential of colloids and charged particles1.5.4 Electroosmosis-fluid motion close to a charged wall in response to an external electric field; 1.6 Particle translocation through nanopores-the model of deBlois and Bean; 1.6.1 Small spheres solution; 1.6.2 "Broad range" solution; References; 2 DNA Translocation; 2.1 Introduction; 2.2 Physics of a polyelectrolyte inside a nanopore; 2.2.1 Electrostatic potential around a charged surface; 2.2.1.1 Nanopore; 2.2.1.2 Polyelectrolyte; 2.3 Electroosmotic flow inside a cylindrically nanopore; 2.4 DNA inside a nanopore , 2.4.1 Free translocation2.5 Capture rate and probability of successful translocation; 2.5.1 Dominating effects; 2.5.1.1 Diffusion-limited regime; 2.5.1.2 Drift regime; 2.5.1.3 Free energy barrier; 2.5.2 Discussion of successful translocation; 2.6 Stalling DNA in a nanopore; 2.6.1 Silicon nitride nanopore with optical tweezers; 2.7 Stalling DNA in nanocapillaries; 2.7.1 Electrostatic characterization; 2.7.2 Force measurements inside glass capillaries; References; 3 Instrumentation for Low-Noise High-Bandwidth Nanopore Recording; 3.1 Introduction , 3.2 Components of a nanopore setup and their integration3.2.1 Nanopore support structure; 3.2.2 Fluidic cell; 3.2.3 Ag/AgCl electrodes; 3.2.4 Noise pickup; 3.3 Low-current measurement techniques; 3.3.1 Shunt resistor; 3.3.2 Resistive feedback; 3.3.3 Capacitive feedback; 3.4 Bandwidth and background noise; 3.4.1 Low-frequency spectrum; 3.4.1.1 Thermal noise; 3.4.1.2 Shot noise; 3.4.1.3 Flicker noise; 3.4.1.4 Protonation noise; 3.4.2 High-frequency spectrum; 3.4.2.1 Dielectric noise; 3.4.2.2 Input capacitance noise; 3.5 Noise filtering, sampling, and resolution , 3.6 Outlook: pushing the detection limit3.6.1.1 Solid-state nanopore devices with reduced capacitance; 3.6.1.2 Integrated nanopores; Ackowledgements; References; 4 Biological Pores on Lipid Bilayers; 4.1 Introduction; 4.2 Formation: overview and experimental protocols; 4.3 Pore characterization: overview and experimental protocols; 4.3.1 Electrophysiological approaches; 4.3.1.1 Critical dimensions; 4.3.1.2 Selectivity; 4.3.2 High-resolution structures; 4.4 Bacterial pore-forming toxins; 4.4.1 α-Hemolysin; 4.4.2 Anthrax protective antigen; 4.5 Bacterial porins; 4.5.1 Outer membrane porins , 4.5.2 Mycobacterium smegmatis: MspA , English

Additional Edition: ISBN 1-4377-3473-1

Language: English

UID:

Format: 1 online resource (211 p.)

Edition: 1st ed.

ISBN: 1-62198-158-4 , 1-84755-890-9

Series Statement: RSC nanoscience & nanotechnology,

Content: In his now celebrated lecture at the 1959 meeting of the American Physical Society, Richard Feynman pondered the potential of miniaturization in the physical sciences. His vision, based on known technology, examined the limits set by physical principles and proposed a variety of new nano-tools including the concept of ""atom-by-atom"" fabrication. In the intervening decades, many of these predictions have become reality. In particular, the development and application of nanofluidics is becoming a competitive and exciting field of research. These nanoscale analytical instruments employ micromac

Note: Description based upon print version of record. , Nanofluidics_publicity; full book resized , English

Additional Edition: ISBN 0-85404-147-8

Language: English

UID:

Format: 1 online resource (xi, 176 pages) : , illustrations (some color).

ISBN: 1-299-39845-6 , 1-4377-3474-X

Series Statement: Micro & nano technologies series

Content: Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necess

Note: Description based upon print version of record. , Front Cover; Engineered Nanopores for Bioanalytical Applications; Copyright Page; List of Contributors; Contents; Introduction; Engineered nanopores for bioanalytical applications; 1 Ion Transport in Nanopores; 1.1 Introduction; 1.2 Brownian motion; 1.3 Net transport of ions: the Nernst-Planck equation and its derivation; 1.4 The conductance of a pore with uncharged walls; 1.4.1 Cylindrical pores; 1.4.2 Pores with noncylindrical geometries; 1.4.3 Access resistance; 1.5 The effect of surface charge; 1.5.1 Charged surfaces in solution; 1.5.2 The conductance of nanopores with charged inner walls , 1.5.3 The ζ-potential of colloids and charged particles1.5.4 Electroosmosis-fluid motion close to a charged wall in response to an external electric field; 1.6 Particle translocation through nanopores-the model of deBlois and Bean; 1.6.1 Small spheres solution; 1.6.2 "Broad range" solution; References; 2 DNA Translocation; 2.1 Introduction; 2.2 Physics of a polyelectrolyte inside a nanopore; 2.2.1 Electrostatic potential around a charged surface; 2.2.1.1 Nanopore; 2.2.1.2 Polyelectrolyte; 2.3 Electroosmotic flow inside a cylindrically nanopore; 2.4 DNA inside a nanopore , 2.4.1 Free translocation2.5 Capture rate and probability of successful translocation; 2.5.1 Dominating effects; 2.5.1.1 Diffusion-limited regime; 2.5.1.2 Drift regime; 2.5.1.3 Free energy barrier; 2.5.2 Discussion of successful translocation; 2.6 Stalling DNA in a nanopore; 2.6.1 Silicon nitride nanopore with optical tweezers; 2.7 Stalling DNA in nanocapillaries; 2.7.1 Electrostatic characterization; 2.7.2 Force measurements inside glass capillaries; References; 3 Instrumentation for Low-Noise High-Bandwidth Nanopore Recording; 3.1 Introduction , 3.2 Components of a nanopore setup and their integration3.2.1 Nanopore support structure; 3.2.2 Fluidic cell; 3.2.3 Ag/AgCl electrodes; 3.2.4 Noise pickup; 3.3 Low-current measurement techniques; 3.3.1 Shunt resistor; 3.3.2 Resistive feedback; 3.3.3 Capacitive feedback; 3.4 Bandwidth and background noise; 3.4.1 Low-frequency spectrum; 3.4.1.1 Thermal noise; 3.4.1.2 Shot noise; 3.4.1.3 Flicker noise; 3.4.1.4 Protonation noise; 3.4.2 High-frequency spectrum; 3.4.2.1 Dielectric noise; 3.4.2.2 Input capacitance noise; 3.5 Noise filtering, sampling, and resolution , 3.6 Outlook: pushing the detection limit3.6.1.1 Solid-state nanopore devices with reduced capacitance; 3.6.1.2 Integrated nanopores; Ackowledgements; References; 4 Biological Pores on Lipid Bilayers; 4.1 Introduction; 4.2 Formation: overview and experimental protocols; 4.3 Pore characterization: overview and experimental protocols; 4.3.1 Electrophysiological approaches; 4.3.1.1 Critical dimensions; 4.3.1.2 Selectivity; 4.3.2 High-resolution structures; 4.4 Bacterial pore-forming toxins; 4.4.1 α-Hemolysin; 4.4.2 Anthrax protective antigen; 4.5 Bacterial porins; 4.5.1 Outer membrane porins , 4.5.2 Mycobacterium smegmatis: MspA , English

Additional Edition: ISBN 1-4377-3473-1

Language: English

UID:

Format: 1 online resource (xi, 176 pages) : , illustrations (some color).

ISBN: 1-299-39845-6 , 1-4377-3474-X

Series Statement: Micro & nano technologies series

Content: Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necess

Note: Description based upon print version of record. , Front Cover; Engineered Nanopores for Bioanalytical Applications; Copyright Page; List of Contributors; Contents; Introduction; Engineered nanopores for bioanalytical applications; 1 Ion Transport in Nanopores; 1.1 Introduction; 1.2 Brownian motion; 1.3 Net transport of ions: the Nernst-Planck equation and its derivation; 1.4 The conductance of a pore with uncharged walls; 1.4.1 Cylindrical pores; 1.4.2 Pores with noncylindrical geometries; 1.4.3 Access resistance; 1.5 The effect of surface charge; 1.5.1 Charged surfaces in solution; 1.5.2 The conductance of nanopores with charged inner walls , 1.5.3 The ζ-potential of colloids and charged particles1.5.4 Electroosmosis-fluid motion close to a charged wall in response to an external electric field; 1.6 Particle translocation through nanopores-the model of deBlois and Bean; 1.6.1 Small spheres solution; 1.6.2 "Broad range" solution; References; 2 DNA Translocation; 2.1 Introduction; 2.2 Physics of a polyelectrolyte inside a nanopore; 2.2.1 Electrostatic potential around a charged surface; 2.2.1.1 Nanopore; 2.2.1.2 Polyelectrolyte; 2.3 Electroosmotic flow inside a cylindrically nanopore; 2.4 DNA inside a nanopore , 2.4.1 Free translocation2.5 Capture rate and probability of successful translocation; 2.5.1 Dominating effects; 2.5.1.1 Diffusion-limited regime; 2.5.1.2 Drift regime; 2.5.1.3 Free energy barrier; 2.5.2 Discussion of successful translocation; 2.6 Stalling DNA in a nanopore; 2.6.1 Silicon nitride nanopore with optical tweezers; 2.7 Stalling DNA in nanocapillaries; 2.7.1 Electrostatic characterization; 2.7.2 Force measurements inside glass capillaries; References; 3 Instrumentation for Low-Noise High-Bandwidth Nanopore Recording; 3.1 Introduction , 3.2 Components of a nanopore setup and their integration3.2.1 Nanopore support structure; 3.2.2 Fluidic cell; 3.2.3 Ag/AgCl electrodes; 3.2.4 Noise pickup; 3.3 Low-current measurement techniques; 3.3.1 Shunt resistor; 3.3.2 Resistive feedback; 3.3.3 Capacitive feedback; 3.4 Bandwidth and background noise; 3.4.1 Low-frequency spectrum; 3.4.1.1 Thermal noise; 3.4.1.2 Shot noise; 3.4.1.3 Flicker noise; 3.4.1.4 Protonation noise; 3.4.2 High-frequency spectrum; 3.4.2.1 Dielectric noise; 3.4.2.2 Input capacitance noise; 3.5 Noise filtering, sampling, and resolution , 3.6 Outlook: pushing the detection limit3.6.1.1 Solid-state nanopore devices with reduced capacitance; 3.6.1.2 Integrated nanopores; Ackowledgements; References; 4 Biological Pores on Lipid Bilayers; 4.1 Introduction; 4.2 Formation: overview and experimental protocols; 4.3 Pore characterization: overview and experimental protocols; 4.3.1 Electrophysiological approaches; 4.3.1.1 Critical dimensions; 4.3.1.2 Selectivity; 4.3.2 High-resolution structures; 4.4 Bacterial pore-forming toxins; 4.4.1 α-Hemolysin; 4.4.2 Anthrax protective antigen; 4.5 Bacterial porins; 4.5.1 Outer membrane porins , 4.5.2 Mycobacterium smegmatis: MspA , English

Additional Edition: ISBN 1-4377-3473-1

Language: English

UID:

Format: XI, 198 S. , Ill., graph. Darst.

ISBN: 9780854041473

Series Statement: RSC nanoscience & nanotechnology 6

Language: English

Subjects: Engineering , Physics

Keywords: Nanostrukturiertes Material ; Nanotechnologie ; Mikrofluidik ; Aufsatzsammlung

URL: Inhaltsverzeichnis

UID:

Format: XIX, 306 Seiten : , Illustrationen, Diagramme (teilweise farbig).

Edition: 2nd edition

ISBN: 978-1-84973-404-2

Series Statement: RSC nanoscience & nanotechnology 41

Additional Edition: Erscheint auch als Online-Ausgabe, EPUB ISBN 978-1-78262-958-0

Additional Edition: Erscheint auch als Online-Ausgabe, PDF ISBN 978-1-84973-523-0

Language: English

Subjects: Engineering , Physics

Keywords: Nanostrukturiertes Material ; Nanotechnologie ; Mikrofluidik ; Aufsatzsammlung

UID:

Format: xi, 198 p. : , ill. (some col.).

Edition: Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.

Series Statement: RSC nanoscience & nanotechnology,

Language: English

Keywords: Electronic books.

URL: Click to View

UID:

Format: XI, 198 S. , Ill., graph. Darst.

Edition: Online-Ausg. 2012 Online-Ressource

ISBN: 9780854041473

Series Statement: RSC nanoscience & nanotechnology [6]

Content: Accessible in style, Nanofluidics fills a gap in the literature for a book focusing on bioanalytical applications within this growing field, In his now celebrated lecture at the 1959 meeting of the American Physical Society, Richard Feynman pondered the potential of miniaturization in the physical sciences. His vision, based on known technology, examined the limits set by physical principles and proposed a variety of new nano-tools including the concept of "atom-by-atom" fabrication. In the intervening decades, many of these predictions have become reality. In particular, the development and application of nanofluidics is becoming a competitive and exciting field of research. These nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency. In a fundamental sense, chip-based analytical systems have been shown to have many advantages over their conventional (larger) analogues. Despite the growth of this field, there are surprisingly few books dedicated to nanofluidics. This book will fill the gap in the literature for a text focusing on bioanalytical applications. Written at a level accessible to experts and non-experts alike, it has the potential to become a mainstream text book for advanced nanobiotechnology courses within academic institutions

Additional Edition: ISBN 9781621981589

Additional Edition: Erscheint auch als Druck-Ausgabe Nanofluidics Cambridge : RSC Publishing, 2009 ISBN 9780854041473

Language: English

Subjects: Engineering , Physics

Keywords: Nanostrukturiertes Material ; Nanotechnologie ; Mikrofluidik

URL: Volltext  (Deutschlandweit zugänglich)

URL: Cover