Format:
Online-Ressource (XVIII, 559 p, online resource)
Edition:
Second Edition
ISBN:
9781597451840
Series Statement:
Cancer Drug Discovery and Development
Content:
Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of ...
Note:
Includes bibliographical references and index
,
Front Matter; Vascular Endothelial Growth Factor Family and Its Receptors; The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumors; The Role of Integrins in Tumor Angiogenesis; Tumor Endothelial Cell Abnormalities; The Extracellular Matrix and VEGF Processing; Endothelial Precursor Cells; Role of Pericytes in Angiogenesis; Newer Vascular Targets; Chemokines in Angiogenesis; Angiopoietin/Tie2 Signaling Regulates Tumor Angiogenesis; Imaging Angiogenesis; Tumor Blood Vessels; Lymphatic System in the Pathology of Cancer; VEGF in the Adult
,
Normalization of Tumor Vasculature and MicroenvironmentMetronomic Low-Dose Antiangiogenic Chemotherapy in Mice and Man; Small-Molecule Vascular Disrupting Agents in Cancer Therapy; Normalization of Tumor Vasculature and Improvement of Radiation Response by Antiangiogenic Agents; Challenges in Translating Antiangiogenic Therapy from the Bench to Bedside; Regulation of Angiogenesis in Cancer and Its Therapeutic Implications; Angiogenesis and Angiogenesis Inhibition in Sarcomas; Antiangiogenesis Agents in Colorectal Cancer; Antiangiogenic Therapy for Primary CNS Tumors
,
Angiogenesis Inhibitors for the Treatment of Lung CancerAntiangiogenic Therapy of Renal Cell Carcinoma; Antiangiogenesis Therapies in Gynecologic Malignancies; Antiangiogenic Agents in Myeloid Malignancies; Angiogenesis in Malignant and Non-Malignant Pediatric Tumors; Prognostic and Predictive Significance of Surrogate Biomarkers of Angiogenesis; Endpoints for the Determination of Efficacy of Antiangiogenic Agents in Clinical Trials; The Role of Imaging in the Clinical Development of Antiangiogenic Agents; Back Matter
Additional Edition:
ISBN 9781588298706
Additional Edition:
Druckausg. ISBN 978-1-58829-870-6
Language:
English
Subjects:
Medicine
Keywords:
Angiogenese
;
Inhibitor
DOI:
10.1007/978-1-59745-184-0
URL:
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