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  • 1
    Online Resource
    Online Resource
    Neuronal activity in tumor tissue / (2007)
    Basel :Karger,
    Details
    UID:
    edoccha_BV036069272
    Format: 1 Online-Ressource (XII, 170 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-01441-9
    Series Statement: Progress in experimental tumor research Vol. 39
    Content: This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer.It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity. Subsequent chapters discuss the interaction between peripheral nerves and tumor cells, the so-called neuro-neoplastic synapse, with regard to carcinogenesis, predictive tumor markers, tumor growth and tumor progression leading to metastasis. In this part, the concept of neoneurogenesis is postulated as a process by which the tumor regulates its own innervation through the release of neurotrophic factors, in analogy to the process of neoangiogenesis discovered three decades ago. Once nerve endings have grown into the tumor, these can release neurotransmitters which promote tumor cell migration and metastasis development. The final chapters reflect on the role of stem cells in neoneurogenesis and consider pharmacological approaches for the inhibition of neuro-neoplastic interactions as a basis for new anticancer therapies.Targeted primarily at investigators in experimental and clinical oncology, this book is also of special interest to neurobiologists as well as developmental and cell biologists
    Note: important implications for the progression and treatment of cancer
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8246-9
    Language: English
    Subjects: Medicine
    RVK:
    XH 8503
    Keywords: Krebszelle ; Peripheres Nervensystem ; Wechselwirkung ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-01441-9
    URL: Volltext
    Author information: Entschladen, Frank
    Author information: Zänker, Kurt S. 1946-
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    Neuronal activity in tumor tissue / (2007)
    Basel :Karger,
    Details
    UID:
    almahu_BV036069272
    Format: 1 Online-Ressource (XII, 170 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-01441-9
    Series Statement: Progress in experimental tumor research Vol. 39
    Content: This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer.It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity. Subsequent chapters discuss the interaction between peripheral nerves and tumor cells, the so-called neuro-neoplastic synapse, with regard to carcinogenesis, predictive tumor markers, tumor growth and tumor progression leading to metastasis. In this part, the concept of neoneurogenesis is postulated as a process by which the tumor regulates its own innervation through the release of neurotrophic factors, in analogy to the process of neoangiogenesis discovered three decades ago. Once nerve endings have grown into the tumor, these can release neurotransmitters which promote tumor cell migration and metastasis development. The final chapters reflect on the role of stem cells in neoneurogenesis and consider pharmacological approaches for the inhibition of neuro-neoplastic interactions as a basis for new anticancer therapies.Targeted primarily at investigators in experimental and clinical oncology, this book is also of special interest to neurobiologists as well as developmental and cell biologists
    Note: important implications for the progression and treatment of cancer
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8246-9
    Language: English
    Subjects: Medicine
    RVK:
    XH 8503
    Keywords: Krebszelle ; Peripheres Nervensystem ; Wechselwirkung ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-01441-9
    URL: Volltext
    Author information: Zänker, Kurt S., 1946-
    Author information: Entschladen, Frank.
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
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    HU Berlin
    EUV Frankfurt
    TH Brandenburg
    TH Wildau
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  • 3
    Online Resource
    Online Resource
    Cell migration : signalling and mechanisms (2010)
    Basel :Karger,
    Details
    UID:
    edoccha_BV039887376
    Format: 1 Online-Ressource (VIII, 176 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-8055-9322-9
    Series Statement: Translational research in biomedicine Vol. 2
    Content: Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell’s ‘migrosome’.With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease
    Note: A unique synopsis for cell biologists, immunologists and oncologists
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-9321-2
    Language: English
    Subjects: Biology
    RVK:
    WE 5320
    Keywords: T-Lymphozyt ; Zellmigration ; Physiologie ; Zellmigration ; Pathophysiologie ; Signaltransduktion ; Physiologie ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-8055-9322-9
    URL: Volltext
    Author information: Entschladen, Frank
    Author information: Zänker, Kurt S. 1946-
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
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    HU Berlin
    EUV Frankfurt
    TH Brandenburg
    TH Wildau
    Charité
    TU Berlin
  • 4
    Online Resource
    Online Resource
    Cell migration : signalling and mechanisms (2010)
    Basel :Karger,
    Details
    UID:
    almahu_BV039887376
    Format: 1 Online-Ressource (VIII, 176 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-8055-9322-9
    Series Statement: Translational research in biomedicine Vol. 2
    Content: Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell’s ‘migrosome’.With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease
    Note: A unique synopsis for cell biologists, immunologists and oncologists
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-9321-2
    Language: English
    Subjects: Biology
    RVK:
    WE 5320
    Keywords: T-Lymphozyt ; Zellmigration ; Physiologie ; Zellmigration ; Pathophysiologie ; Signaltransduktion ; Physiologie ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-8055-9322-9
    URL: Volltext
    Author information: Zänker, Kurt S., 1946-
    Author information: Entschladen, Frank.
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Online Access
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    HU Berlin
    EUV Frankfurt
    TH Brandenburg
    TH Wildau
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    TU Berlin
  • 5
    Online Resource
    Online Resource
    Neuronal activity in tumor tissue (2007)
    Basel : Karger
    Details
    UID:
    b3kat_BV036069272
    Format: 1 Online-Ressource (XII, 170 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318014419
    Series Statement: Progress in experimental tumor research Vol. 39
    Content: This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer.It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity. Subsequent chapters discuss the interaction between peripheral nerves and tumor cells, the so-called neuro-neoplastic synapse, with regard to carcinogenesis, predictive tumor markers, tumor growth and tumor progression leading to metastasis. In this part, the concept of neoneurogenesis is postulated as a process by which the tumor regulates its own innervation through the release of neurotrophic factors, in analogy to the process of neoangiogenesis discovered three decades ago. Once nerve endings have grown into the tumor, these can release neurotransmitters which promote tumor cell migration and metastasis development. The final chapters reflect on the role of stem cells in neoneurogenesis and consider pharmacological approaches for the inhibition of neuro-neoplastic interactions as a basis for new anticancer therapies.Targeted primarily at investigators in experimental and clinical oncology, this book is also of special interest to neurobiologists as well as developmental and cell biologists
    Note: important implications for the progression and treatment of cancer
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8246-9
    Language: English
    Subjects: Medicine
    RVK:
    XH 8503
    Keywords: Krebszelle ; Peripheres Nervensystem ; Wechselwirkung ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-01441-9
    URL: Volltext
    Author information: Entschladen, Frank
    Author information: Zänker, Kurt S. 1946-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Online Access
    Open Access Request
    EUV Frankfurt
    TH Brandenburg
    TH Wildau
    TU Berlin
  • 6
    Online Resource
    Online Resource
    Cell migration : signalling and mechanisms (2010)
    Basel : Karger
    Details
    UID:
    b3kat_BV039887376
    Format: 1 Online-Ressource (VIII, 176 Seiten) , Illustrationen, Diagramme
    ISBN: 9783805593229
    Series Statement: Translational research in biomedicine Vol. 2
    Content: Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell’s ‘migrosome’.With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease
    Note: A unique synopsis for cell biologists, immunologists and oncologists
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-9321-2
    Language: English
    Subjects: Biology
    RVK:
    WE 5320
    Keywords: T-Lymphozyt ; Zellmigration ; Physiologie ; Zellmigration ; Pathophysiologie ; Signaltransduktion ; Physiologie ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-8055-9322-9
    URL: Volltext
    Author information: Entschladen, Frank
    Author information: Zänker, Kurt S. 1946-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Online Access
    Open Access Request
    EUV Frankfurt
    TH Brandenburg
    TH Wildau
    TU Berlin
  • 7
    Online Resource
    Online Resource
    Neuronal activity in tumor tissue / (2007)
    Basel :Karger,
    Details
    UID:
    almafu_BV036069272
    Format: 1 Online-Ressource (XII, 170 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-01441-9
    Series Statement: Progress in experimental tumor research Vol. 39
    Content: This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer.It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity. Subsequent chapters discuss the interaction between peripheral nerves and tumor cells, the so-called neuro-neoplastic synapse, with regard to carcinogenesis, predictive tumor markers, tumor growth and tumor progression leading to metastasis. In this part, the concept of neoneurogenesis is postulated as a process by which the tumor regulates its own innervation through the release of neurotrophic factors, in analogy to the process of neoangiogenesis discovered three decades ago. Once nerve endings have grown into the tumor, these can release neurotransmitters which promote tumor cell migration and metastasis development. The final chapters reflect on the role of stem cells in neoneurogenesis and consider pharmacological approaches for the inhibition of neuro-neoplastic interactions as a basis for new anticancer therapies.Targeted primarily at investigators in experimental and clinical oncology, this book is also of special interest to neurobiologists as well as developmental and cell biologists
    Note: important implications for the progression and treatment of cancer
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8246-9
    Language: English
    Subjects: Medicine
    RVK:
    XH 8503
    Keywords: Krebszelle ; Peripheres Nervensystem ; Wechselwirkung ; Aufsatzsammlung
    DOI: 10.1159/isbn.978-3-318-01441-9
    URL: Volltext
    URL: lizenzpflichtig
    URL: Volltext
    Author information: Entschladen, Frank
    Author information: Zänker, Kurt S. 1946-
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
    Open Access Request
    Stabi Berlin
    UB Potsdam
    Charité
    MPI Bildungsforschung
  • 8
    Online Resource
    Online Resource
    Cell migration: signalling and mechanisms : 2 tables (2010)
    Basel : Karger
    Details
    UID:
    gbv_1652123563
    Format: Online Ressource (VIII, 176 S.)
    Edition: Online-Ausg.
    ISBN: 3805593228 , 9781282500754 , 9783805593229
    Series Statement: Translational research in biomedicine 2
    Content: Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell’s ‘migrosome’. With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease.
    Note: Dateiformat: PDF , Cover; Contents; Foreword; Preface; The Migrating Cell; Stem Cell Migration in Health and Disease; Leukocyte Motility and Human Disease; Coordination of Leukocyte Polarity and Migration; Positioning Phosphoinositide 3-Kinase inChemokine and Antigen-Dependent T-Lymphocyte Navigation Mechanisms; Migration of Functionally SpecializedT-Helper Cells: TFH Cells, Th17 Cells and FoxP3+ T Cells; ADAMs and Ectodomain Proteolytic Shedding in Leukocyte and Tumour Cell Migration; Guided Tour of Cell Migration: Signals and Pathways , Regulation of the E-Cadherin Adhesion Complex in Tumor Cell Migration andInvasionThe Cytoskeletal Connection: Understanding Adaptor Proteins; Locomotor Force Generation by Myosins; Author Index; Subject Index , The migrating cell / Entschladen, F., Zänker, K.S. -- Stem cell migration in health and disease / Dittmar, T. ... [et al.] -- Leukocyte motility and human disease / Cooper, K., Nuzzi, P., Huttenlocher, A. -- Coordination of leukocyte polarity and migration / Martín-Cófreces, N.B., Serrador, J.M., Sánchez-Madrid, F. -- Positioning phosphoinositide 3-kinase in chemokine and antigen-dependent T-lymphocyte navigation mechanisms / Ward, S.G. -- Migration of functionally specialized T-helper cells : TFH cells, Th17 cells, and FoxP3+ T cells / Kim, C.H. -- ADAMs and ectodomain proteolytic shedding in leukocyte and tumour cell migration / Ager, A., Knäuper, V., Poghosyan, Z. -- Guided tour of cell migration : signals and pathways / Ratke, J., Lang, K. -- Regulation of the E-cadherin adhesion complex in tumor cell migration and invasion / Menke, A., Giehl, K. -- The cytoskeletal connection : understanding adaptor proteins / Ziegler, W.H. -- Locomotor force generation by myosins / Jbireal, J.M.A., Entschladen, F., Zänker, K.S , The migrating cell / Entschladen, F., Zänker, K.S.Stem cell migration in health and disease / Dittmar, T. ... [et al.] -- Leukocyte motility and human disease / Cooper, K., Nuzzi, P., Huttenlocher, A. -- Coordination of leukocyte polarity and migration / Martín-Cófreces, N.B., Serrador, J.M., Sánchez-Madrid, F. -- Positioning phosphoinositide 3-kinase in chemokine and antigen-dependent T-lymphocyte navigation mechanisms / Ward, S.G. -- Migration of functionally specialized T-helper cells : TFH cells, Th17 cells, and FoxP3+ T cells / Kim, C.H. -- ADAMs and ectodomain proteolytic shedding in leukocyte and tumour cell migration / Ager, A., Knäuper, V., Poghosyan, Z. -- Guided tour of cell migration : signals and pathways / Ratke, J., Lang, K. -- Regulation of the E-cadherin adhesion complex in tumor cell migration and invasion / Menke, A., Giehl, K. -- The cytoskeletal connection : understanding adaptor proteins / Ziegler, W.H. -- Locomotor force generation by myosins / Jbireal, J.M.A., Entschladen, F., Zänker, K.S.
    Additional Edition: ISBN 9783805593212
    Additional Edition: ISBN 9783805593212
    Additional Edition: Erscheint auch als Druck-Ausgabe Cell migration: signalling and mechanisms Basel : Karger, 2010 ISBN 9783805593212
    Language: English
    Subjects: Biology
    RVK:
    WE 5320
    Keywords: T-Lymphozyt ; Zellmigration ; Physiologie ; Zellmigration ; Pathophysiologie ; Signaltransduktion ; Physiologie ; Electronic books ; Aufsatzsammlung
    URL: lizenzpflichtig
    URL: Volltext
    URL: Inhaltsverzeichnis
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    MPI Bildungsforschung
  • 9
    Online Resource
    Online Resource
    Neuronal activity in tumor tissue / (2007)
    Basel ; : Karger,
    Details
    UID:
    almafu_9958076726402883
    Format: 1 online resource (181 p.)
    ISBN: 1-280-84346-2 , 9786610843466 , 3-318-01441-9 , 1-4294-6851-3
    Series Statement: Progress in experimental tumor research ; v. 39
    Content: This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer.It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity. Subsequent chapters discuss the interaction between peripheral nerves and tumor cells, the so-called neuro-neoplastic synapse, with regard to carcinogenesis, predictive tumor markers, tumor growth and tumor progression leading to metastasis. In this part, the conce
    Note: Description based upon print version of record. , Cover; Contents; In Remembrance of Fritz Bender Esq. (1907 -1986); Foreword; Neuronal Development; Organization of Peripheral Nerves in Skin, Musculoskeletal System and Viscera; Neurotransmitter Receptor-Mediated Signaling Pathways as Modulators of Carcinogenesis; Neuronal Markers in Non-Neuronal Tissues; Chemotropic Axon Guidance Molecules in Tumorigenesis; Neoneurogenesis and the Neuro-Neoplastic Synapse; Neurotransmitter Effects on Tumor Cells and Leukocytes; Stem Cells and Neurogenesis in Tumors , Potential Inhibition of the Neuro-Neoplastic Interactions: The Clue of a GPCR-Targeted TherapyThe Neuro-Neoplastic Synapse: Does it Exist?; Author Index; Subject Index , English
    Additional Edition: ISBN 3-8055-8246-3
    Language: English
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    Online Resource
    FU Berlin
    Charité
  • 10
    Book
    Book
    Cell migration : signalling and mechanisms (2010)
    Basel [u.a.] :Karger,
    Details
    UID:
    almahu_BV036009710
    Format: VIII, 176 S. : , Ill., graph. Darst.
    ISBN: 978-3-8055-9321-2 , 3-8055-9321-X , 978-3-8055-9322-9
    Series Statement: Translational research in biomedicine 2
    Note: Literaturangaben
    Language: English
    Subjects: Biology
    RVK:
    WE 5320
    Keywords: T-Lymphozyt ; Zellmigration ; Physiologie ; Zellmigration ; Pathophysiologie ; Signaltransduktion ; Physiologie ; Aufsatzsammlung
    URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018901960&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
    URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018901960&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
    Author information: Entschladen, Frank.
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