UID:
almafu_9960117174802883
Format:
1 online resource (xiv, 579 pages) :
,
digital, PDF file(s).
ISBN:
1-316-08618-6
,
1-280-70319-9
,
9786610703197
,
0-511-24980-2
,
0-511-24872-5
,
0-511-25031-2
,
0-511-31931-2
,
0-511-54174-0
,
0-511-24927-6
Content:
Basic relevant information on methodologies used in neurological disease models can be extremely hard to find. Originally published in 2006, this important reference work contains 30 chapters from over 60 internationally recognized scientists and covers every major methodology and disease model used in neuroscience research. Divided into two major sections, the first deals with general methodologies in neuroscience research covering topics from animal welfare and ethical issues to surgical procedures, post-operative care and behavioral testing. Section two covers every major disease model including traumatic brain injury, ischemia and stroke, to Parkinson's, motor neurone disease, epilepsy and sleep disorders. Delivering critical methodological information and describing small animal models for almost all major neurological diseases, this book forms an essential reference for anyone working in neuroscience, from beginning students to experienced researchers and medical professionals.
Note:
Title from publisher's bibliographic system (viewed on 05 Oct 2015).
,
Cover; Half-title; Title; Copyright; Contents; Contributors; 1 Introduction: Animal modeling - a precious tool for developing remedies to neurological diseases; 2 Ethical issues, welfare laws, and regulations; 3 Housing, feeding, and maintenance of rodents; 4 Identification of individual animals; 5 Analgesia, anesthesia, and postoperative care in laboratory animals; 6 Euthanasia in small animals; 7 Various surgical procedures in rodents; 8 Genetically engineered animals; 9 Imaging in experimental neurology; 10 Safety in animal facilities
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11 Behavioral testing in small-animal models: ischemic stroke12 Methods for analyzing brain tissue; 13 Targeting molecular constructs of cellular function and injury through in vitro and in vivo experimental models; 14 Neuroimmunology and immune-related neuropathologies; 15 Animal models of sex differences in non-reproductive brain functions; 16 The ependymal route for central nervous system gene therapy; 17 Neural transplantation; 18 Focal brain ischemia models in rodents; 19 Rodent models of global cerebral ischemia; 20 Rodent models of hemorrhagic stroke
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21 In vivo models of traumatic brain injury22 Experimental models for the study of CNS tumors; 23 Experimental models for demyelinating diseases; 24 Animal models of Parkinson's disease; 25 Animal models of epilepsy; 26 Experimental models of hydrocephalus; 27 Rodent models of experimental bacterial infections in the CNS; 28 Experimental models of motor neuron disease/amyotrophic lateral sclerosis; 29 Animal models for sleep disorders; 30 Experimental models of muscle diseases; Index
,
English
Additional Edition:
ISBN 0-521-18420-7
Additional Edition:
ISBN 0-521-83814-2
Language:
English
URL:
https://doi.org/10.1017/CBO9780511541742
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