UID:
edoccha_9961089707802883
Format:
1 online resource (428 pages)
ISBN:
0-12-812676-0
Content:
Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.
Note:
Introduction -- Is the Classic Spermiogram Still Informative? How Did It Develop and Where Is It Going? / William V. Holt -- Genetic Variations and Male Infertility / Sezgin Gunes, Ashok Agarwal, Aysenur Ersoy, Ralf Henkel -- New Genetic Point Mutations in Male Infertility / Xavier Vendrell -- Carrier Screening for Inherited Genetic Disorders : A Review of Current Practices / Neha Kumar, Sally Ann Rodríguez -- Telomeres in Germ Line and Early Embryo : An Overview / José Luís Fernández, Iria González-Vasconcellos -- Human Protamine Genes' Polymorphisms as a Possible Cause Underlying Male Infertility / Anaís García Rodríguez, Rosa Roy Barcelona -- Small RNAs Present in Semen and Their Role in Reproduction / Meritxell Jodar, Ester Anton -- Altered Transcriptomic Profiles Associated With Male Infertility / Sara Larriba, Lluís Bassas -- Proteomics and Metabolomics Studies and Clinical Outcomes / Giulia Mariani, José Bellver -- Epigenetics, Spermatogenesis, and Male Infertility / sezgin Gunes, Ahmet Kablan, Ashok Agarwal, Ralf Henkel -- Changes in DNA Methylation Related to Male Infertility / R.G. Urdinguio, M.F. Fraga, A.F. Fernández -- Noninvasive Methods of Embryo Selection / Sergio Oehninger -- Genetic Selection of the Human Embryos : From FISH to NGS, Past and Future / Sarthak Sawarkar, Santiago Munne -- Unraveling the Causes of Failed Fertilization After Intracytoplasmic Sperm Injection Due to Oocyte Activation Deficiency / Davina Bonte, Ramesh Reddy Guggilla, Panagiotis Stamatiadis, Petra De Sutter, Björn Heindryckx -- The Molecular Signature of the Endometrial Receptivity : Research and Clinical Application / José P. Carrascosa, José A. Horcajadas, Juan M. Moreno-Moya -- The Acquisition of the Human Endometrial Receptivity Phenotype : Lessons From Proteomic Studies / Delphine Haouzi, Sami Hamamah -- Stem Cell-Derived Spermatozoa / Jasin Taelman, Swati Mishra, Margot Van der Jeught, Björn Heindryckx -- Computational Approaches in Reproductomics / Eva Vargas, Francisco J. Esteban, Signe Altmäe -- Conclusions--Year 2020 : The "-Omics" Technologies and Personalized Assisted Reproduction / José A. Horcajadas, Jaime Gosálvez.
Additional Edition:
ISBN 0-12-812571-3
Language:
English
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