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  • 1
    Online Resource
    Online Resource
    The book of Ecclesiastes paraphrased : A divine poem. By A. Hill (1712)
    Newcastle upon Tine : printed and sold by J. White, at his House on the Side
    Details
    UID:
    gbv_552502480
    Format: Online-Ressource ([2],vi,47,[1]p) , 8°
    Edition: Online-Ausg. Farmington Hills, Mich Cengage Gale 2009 Eighteenth Century Collections Online Electronic reproduction; Available via the World Wide Web
    Note: English Short Title Catalog, T124718 , Foxon, H235 , Reproduction of original from British Library , Electronic reproduction; Available via the World Wide Web
    Language: English
    URL: Volltext  (Full text online)
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
  • 2
    Online Resource
    Online Resource
    Vaccine Delivery Technology : Methods and Protocols (2021)
    New York, NY :Springer US :
    Details
    UID:
    almahu_9949251306002882
    Format: 1 online resource (XV, 590 p. 149 illus., 127 illus. in color.)
    Edition: 1st ed. 2021.
    ISBN: 1-0716-0795-2
    Series Statement: Methods in Molecular Biology, 2183
    Content: This volume discusses the vaccine development process and the role delivery concepts contribute to a global goal of effective health outcomes. The chapters in this book cover a wide range of topics such as antigen discovery methods; genetic and protein antigen preparation; preparation of viral vaccines as VLPs; viral and non-viral gene delivery; needle-less or non-invasive delivery technology; vaccine storage; and vaccine administration and assessment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics; lists of the necessary materials and reagents; step-by-step, readily reproducible laboratory protocols; and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vaccine Delivery Technology: Methods and Protocols is a valuable resource for both novice and expert researchers, in and outside the field, who would like to gain insight into the impactful field of vaccines. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Note: Vaccine Delivery and Immune Response Basics -- Isolating Pathogen-Specific Human Monoclonal Antibodies (hmAbs) using Bacterial Whole Cells as Molecular Probes -- Use of Chlamydial Elementary Bodies as probes to Isolate Pathogen-Specific Human Monoclonal Antibodies -- Computational Antigen Discovery for Eukaryotic Pathogens using Vacceed -- Antigen Discovery in Bacterial Pan-Proteomes -- Alphavirus-Based Antigen Preparation -- Production of Chimeric Hepatitis B Virus Surface Antigens in Mammalian Cells -- Bioreactor-Based Antigen Production Process using the Baculovirus Expression Vector System -- High-Throughput Process Development for the Chromatographic Purification of Viral Antigens -- Production of Zika Virus Virus-Like Particles -- Biosynthesis of Glycoconjugate Virus-Like Particles (VLPs) -- Up- and Downstream Processes for Viral Nanoplaxes as Vaccines -- Whole-Cell Vaccine Preparation: Options and Perspectives -- O-Antigen Extraction, Purification, and Chemical Conjugation to a Carrier Protein -- Oligosaccharide Antigen Conjugation to Carrier Proteins to Formulate Glycoconjugate Vaccines -- Exploitation of Capsule Polymerases for the Enzymatic Synthesis of the Polysaccharide Antigens used in Glycoconjugate Vaccines -- Attenuation Methods for Live Vaccines -- Surface Modification of Adenovirus Vector to Improve Immunogenicity and Tropism -- Production of Baculovirus and Stem Cells for Baculovirus-Mediated Gene Transfer into Human Mesenchymal Stem Cells -- Lipofection-Based Delivery of DNA Vaccines -- Flavivirus DNA Vaccine Design and Adjuvant Selection -- Vaccine Delivery with a Detoxified Bacterial Toxin -- Needle-Less or Non-Invasive Delivery Technology -- Lactic Acid Bacteria as Delivery Vehicle for Therapeutics Applications -- A Hybrid Biological-Biomaterial Vector for Antigen Delivery -- Liposomal Dual Delivery of Both Polysaccharide and Protein Antigens -- Thin-Film Freeze-Drying is a Viable Method to Convert Vaccines Containing Aluminum Salts from Liquid to Dry Powder -- The Application of Cryogenic Transmission Electron Microscopy for Evaluation of Vaccine Delivery Carriers -- Methods to Evaluate Immune Cell Recruitment and the Cellular Uptake and Distribution of Antigen following Intramuscular Administration of Vaccine to Mice -- The Quantification of Antigen-Specific T Cells by IFN-γ ELISpot -- The Measurement of Antigen-Specific IgG Titers by Direct ELISA -- Method to Evaluate In Vivo CD8+ T Cell Cytotoxicity in a Murine Model -- Testing Anti-Pneumococcal Antibody Function using Bacteria and Primary Neutrophils -- Viral Infectivity Qunatification and Neutralization Assays using Laser Force Cytology.
    Additional Edition: ISBN 1-0716-0794-4
    Language: English
    DOI: 10.1007/978-1-0716-0795-4
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  • 3
    Online Resource
    Online Resource
    Exosomes and Microvesicles : Methods and Protocols (2017)
    New York, NY :Springer New York :
    Details
    UID:
    almahu_9949251577802882
    Format: 1 online resource (XII, 228 p. 39 illus., 21 illus. in color.)
    Edition: 1st ed. 2017.
    ISBN: 1-4939-6728-2
    Series Statement: Methods in Molecular Biology, 1545
    Content: This volume covers methods for the analysis of extracellular vesicles (EV) that can be applied to isolated EVs from a wide variety of sources. This includes the use of electron microscopy, tunable resistance pulse sensing, and nanoparticle tracking analysis. The chapters in this book discuss EV cargoes containing proteins and genomic materials using a number of different approaches, and isolating EVs from platelets and neuronal cells and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and comprehensive, Exosomes and Microvesicles: Methods and Protocols is a valuable resource containing methodologies for anyone interested in researching EVs.
    Note: Methods to Analyze EVs -- Tunable Resistive Pulse Sensing for the Characterization of Extracellular Vesicles -- Immuno-Characterization of Exosomes using Nanoparticle Tracking Analysis -- Imaging and Quantification of Extracellular Vesicles by Transmission Electron Microscopy -- Quantitative Analysis of Exosomal miRNA via qPCR and Digital PCR -- Small RNA Library Construction for Exosomal RNA from Biological Samples for the Ion Torrent PGM™ System -- A Protocol for Isolation and Proteomic Characterization of Distinct Extracellular Vesicle Subtypes by Sequential Centrifugal Ultrafiltration -- Multiplexed Phenotyping of Extracellular Vesicles using Protein Microarray (EV Array) -- Purification and Analysis of Exosomes Released by Mature Cortical Neurons following Synaptic Activation -- A Method for Isolation of Extracellular Vesicles and Characterization of Exosomes from Brain Extracellular Space -- Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission -- Isolation of Platelet-Derived Extracellular Vesicles -- Bioinformatics Tools for Extracellular Vesicles Research -- Preparation and Isolation of siRNA-Loaded Extracellular Vesicles -- Interaction of Extracellular Vesicles with Endothelial Cells under Physiological Flow Conditions.
    Additional Edition: ISBN 1-4939-6726-6
    Language: English
    Keywords: Laboratory Manuals. ; Laboratory manuals. ; Laboratory Manuals. ; Laboratory manuals.
    DOI: 10.1007/978-1-4939-6728-5
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  • 4
    Online Resource
    Online Resource
    Sound and image : aesthetics and practices (2020)
    Abingdon, Oxon ; : Routledge,
    Details
    UID:
    almahu_9949386011602882
    Format: 1 online resource.
    ISBN: 9780429295102 , 0429295103 , 0367271478 , 9780367271473 , 9781000069945 , 100006994X
    Series Statement: Sound design
    Content: "Sound and Image: Aesthetics and Practices brings together international artist scholars to explore diverse sound and image practices, applying critical perspectives to interrogate and evaluate both the aesthetics and practices that underpin the audiovisual. Contributions draw upon established discourses in electroacoustic music, media art history, film studies, critical theory and dance; framing and critiquing these arguments within the context of diverse audiovisual practices. The volume's interdisciplinary perspective contributes to the rich and evolving dialogue surrounding the audiovisual, demonstrating the value and significance of practice informed theory, and theory derived from practice. The ideas and approaches explored within this book will find application in a wide range of contexts across the whole scope of audiovisuality, from visual music and experimental film, to narrative film and documentary, to live performance, sound design and into sonic art and electroacoustic music. This book is ideal for artists, composers and researchers investigating theoretical positions and compositional practices which bring together sound and image"--
    Note: Connected Media, Connected Idioms : The Relationship Between Video and Electroacoustic Music From A Composers Perspective / Diego Garro -- Sound/Image Relations in Videomusic : A Typological Proposition / Myriam Boucher & Jean Piché -- The Question of Form in Visual Music / Maura McDonnell -- Audiovisual Spaces : Spatiality, Experience and Potentiality in Audiovisual Composition / Andrew Knight-Hill -- Rhythm as The Intermediary of Audiovisual Fusions / Daniel Von Rüdiger -- The Curious Case of The Plastic Hair-Comb : A Rhythm-Based Approach to A Parallel (Sound-Image-Touch) Theory of Aesthetic Practices / Matthew Galea -- The Spaces Between Gesture, Sound and Image / Mark Pedersen Brigid Burke Roger Alsop -- The Gift of Sound and Vision : Visual Music as A Form of Glossolalic Speech / Philip Sanderson -- Visual Music and Embodied Visceral Affect / Julie Watkins -- The Function of Mickey-Mousing : A Re-Assessment / Emilio Audissino -- Performing the Real : Audiovisual Documentary Performances and The Senses / Cornelia Lund -- Blending Image and Music in Jim Jarmusch's Cinema / Celine Murillo -- The New Analogue : Media Archaeology as Creative Practice in 21st Century Audiovisual Art / Joseph Hyde -- Screen Grammar for Mobile Frame Media : The Audiovisual Language of Cinematic Virtual Reality, Case Studies and Analysis / Sam Gillies -- Nature Morte / Jim Hobbs -- Capturing Movement: A Videomusical Approach Sourced in The Natural Environment / Myriam Boucher -- Constructing Visual Music Images with Electroacoustic Music Concepts / Maura McDonnell -- Technique and Audiovisual Counterpoint in The Estuaries Series / Bret Battey -- Exploring Expanded Audiovisual Formats (EAFs) -- A Practitioner's Perspective / Dr Louise Harris -- Making A Motion Score : A Graphical and Genealogical Inquiry into A Multi-Screen Cinegraphy / Leyokki -- The Human Body as an Audiovisual Instrument / Claudia Robles-Angel -- Sound -- [Object] -- Dance : A Holistic Approach to Interdisciplinary Composition / Jung In Jung -- Son e(s)t Lumière : Expanding Notions of Composition, Transcription and Tangibility Through Creative Sonification Of Digital Images / Simon Cummings -- Audiovisual Heterophony : A Musical Reading of Walter Ruttmann's Film Lichtspiel Opus 3 (1924) / Tom Reid.
    Additional Edition: Print version: Sound and image New York : Routledge, 2020. ISBN 9780367271473
    Language: English
    Keywords: Electronic books. ; Criticism, interpretation, etc.
    URL: https://www.taylorfrancis.com/books/9780429295102
    URL: Volltext  (URL des Erstveroeffentlichers)
    URL: lizenzpflichtig
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    Online Access
  • 5
    Online Resource
    Online Resource
    Protein Folding, Misfolding, and Disease : Methods and Protocols (2011)
    Totowa, NJ :Humana Press :
    Details
    UID:
    almahu_9949251330902882
    Format: 1 online resource (X, 230 p. 50 illus.)
    Edition: 1st ed. 2011.
    ISBN: 1-60327-223-2
    Series Statement: Methods in Molecular Biology, 752
    Content: Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease.  In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field.
    Note: Bibliographic Level Mode of Issuance: Monograph , Strategies for Boosting the Accumulation of Correctly Folded Recombinant Proteins Expressed in Escherichia coli -- An Escherichia coli Cell-Free System for Recombinant Protein Synthesis on a Milligram Scale -- Synthesis of Peptide Sequences Derived from Fibril-Forming Proteins -- Refolding Your Protein with a Little Help from REFOLD -- Circular Dichroism and Its Use in Protein Folding Studies -- Distance Measurements by Continuous Wave EPR Spectroscopy to Monitor Protein Folding -- Solution-State Nuclear Magnetic Resonance Spectroscopy and Protein Folding -- Diagnostics for Amyloid Fibril Formation: Where to Begin -- Probing Protein Aggregation with Quartz Crystal Microbalances -- Dried and Hydrated X-Ray Scattering Analysis of Amyloid Fibrils -- Solid-State NMR of Amyloid Membrane Interactions -- Sedimentation Velocity Analysis of Amyloid Fibrils -- Transmission Electron Microscopy of Amyloid Fibrils -- Surface Plasmon Resonance Spectroscopy: A New Lead in Studying the Membrane Binding of Amyloidogenic Transthyretin -- Elucidating the Role of Metals in Alzheimer’s Disease through the Use of Surface Enhanced Laser Desorption / Ionisation Time-of-Flight Mass Spectrometry. , English
    Additional Edition: ISBN 1-60327-221-6
    Language: English
    DOI: 10.1007/978-1-60327-223-0
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  • 6
    Online Resource
    Online Resource
    Prion Protein Protocols / (2008)
    Totowa, NJ :Humana Press :
    Details
    UID:
    almahu_9949251524002882
    Format: 1 online resource (XIV, 280 p. 43 illus., 5 illus. in color.)
    Edition: 1st ed. 2008.
    ISBN: 1-59745-234-3
    Series Statement: Methods in Molecular Biology, 459
    Content: While much information has been gained over the last two decades regarding the molecular nature of prion proteins, only recently have several research groups begun to cast light on turning the normal prion protein into its aberrant, infectious form. In Prion Protein Protocols, an international team of experts provide an up-to-date collection of current methods in this unique area of neuroscience. The chapters contained in this volume, both protocols and useful review chapters, feature topics such as the cell biology of prions, techniques and approaches to studying prion infection in cultured cells, how these systems can be used as a rapid bioassay, and prion protein misfolding. As a volume in the highly successful Methods in Molecular Biology™ series, the chapters include readily reproducible, step-by-step laboratory protocols, lists of the necessary materials and reagents, and the Notes section, which provides tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Prion Protein Protocols is an ideal collection for researchers investigating the growing field of mammalian prion disease.
    Note: Bibliographic Level Mode of Issuance: Monograph , Cell Culture Models to Unravel Prion Protein Function and Aberrancies in Prion Diseases -- Investigation of PrPC Metabolism and Function in Live Cells -- Immunodetection of PrPSc Using Western and Slot Blotting Techniques -- Assaying Prions in Cell Culture -- Generation of Cell Lines Propagating Infectious Prions and the Isolation and Characterization of Cell-derived Exosomes -- Neurotoxicity of Prion Peptides on Cultured Cerebellar Neurons -- Understanding the Nature of Prion Diseases Using Cell-free Assays -- Methods for Conversion of Prion Protein into Amyloid Fibrils -- Amplification of Purified Prions In Vitro -- Expression and Purification of Full-Length Recombinant PrP of High Purity -- Analysis of PrP Conformation Using Circular Dichroism -- Effect of Copper on the De Novo Generation of Prion Protein Expressed in Pichia pastoris -- Biophysical Investigations of the Prion Protein Using Electron Paramagnetic Resonance -- Molecular Diagnosis of Human Prion Disease -- Analysis of Endogenous PrPC Processing in Neuronal and Non-neuronal Cell Lines -- Molecular Typing of PrPres in Human Sporadic CJD Brain Tissue -- Transgenic Mouse Models of Prion Diseases -- Quantitative Bioassay of Surface-bound Prion Infectivity. , English
    Additional Edition: ISBN 1-58829-897-3
    Language: English
    DOI: 10.1007/978-1-59745-234-2
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  • 7
    Book
    Book
    Prion protein protocols (2008)
    Totowa, N.J. : Humana Press
    Details
    UID:
    gbv_563435038
    Format: XIII, 280 S. , Ill., graph. Darst. , 24 cm
    ISBN: 1588298973 , 9781588298973
    Series Statement: Methods in molecular biology 459
    Note: Cell culture models to unravel prion protein function and aberrancies in prion diseases / Katarina BedecsInvestigation of PrPc metabolism and function in live cells : methods for studying individual cells and cell populations / Cathryn L. Haigh and David R. Brown -- Immunodetection of PrPsc using western and slot blotting techniques / Hanny Gyllberg and Kajsa Löfgren -- Assaying prions in cell culture : the standard scrapie cell assay (SSCA) and the scrapie cell assay in end point format (SCEPA) / Sukhvir P. Mahal ... [et al.] -- Generation of cell lines propagating infectious prions and the isolation and characterization of cell-derived exosomes / Laura J. Vella and Andrew F. Hill -- Neurotoxicity of prion peptides on cultured cerebellar neurons / Giuseppe D. Ciccotosto, Roberto Cappai, and Anthony R. White -- Understanding the nature of prion diseases using cell-free assays / Victoria A. Lawson -- Methods for conversion of prion protein into amyloid fibrils / Leonid Breydo, Natallia Makarava, and Ilia V. Baskakov -- Amplification of purified prions in vitro / Surachai Supattapone, Nathan R. Deleault, and Judy R. Rees -- Expression and purification of full-length recombinant PrP of high purity / Natallia Makarava and Ilia V. Baskakov -- Analysis of PrP conformation using circular dichroism / Sen Han and Andrew F. Hill -- Effect of copper on the de novo generation of prion protein expressed in Pichia pastoris / Carina Treiber -- Biophysical investigations of the prion protein using electron paramagnetic resonance / Simon C. Drew and Kevin J. Barnham -- Molecular diagnosis of human prion disease / Jonathan D.F. Wadsworth ... [et al.] -- Analysis of endogenous PrPc processing in neuronal and non-neuronal cell lines / Victoria Lewis and Steven J. Collins -- Molecular typing of PrPres in human sporadic CJD brain tissue / Victoria Lewis ... [et al.] -- Transgenic mouse models of prion diseases / Glenn C. Telling -- Quantitiative bioassay of surface-bound prion infectivity / Victoria A. Lawson. , Cell culture models to unravel prion protein function and aberrancies in prion diseases / Katarina Bedecs -- Investigation of PrPc metabolism and function in live cells : methods for studying individual cells and cell populations / Cathryn L. Haigh and David R. Brown -- Immunodetection of PrPsc using western and slot blotting techniques / Hanny Gyllberg and Kajsa Löfgren -- Assaying prions in cell culture : the standard scrapie cell assay (SSCA) and the scrapie cell assay in end point format (SCEPA) / Sukhvir P. Mahal ... [et al.] -- Generation of cell lines propagating infectious prions and the isolation and characterization of cell-derived exosomes / Laura J. Vella and Andrew F. Hill -- Neurotoxicity of prion peptides on cultured cerebellar neurons / Giuseppe D. Ciccotosto, Roberto Cappai, and Anthony R. White -- Understanding the nature of prion diseases using cell-free assays / Victoria A. Lawson -- Methods for conversion of prion protein into amyloid fibrils / Leonid Breydo, Natallia Makarava, and Ilia V. Baskakov -- Amplification of purified prions in vitro / Surachai Supattapone, Nathan R. Deleault, and Judy R. Rees -- Expression and purification of full-length recombinant PrP of high purity / Natallia Makarava and Ilia V. Baskakov -- Analysis of PrP conformation using circular dichroism / Sen Han and Andrew F. Hill -- Effect of copper on the de novo generation of prion protein expressed in Pichia pastoris / Carina Treiber -- Biophysical investigations of the prion protein using electron paramagnetic resonance / Simon C. Drew and Kevin J. Barnham -- Molecular diagnosis of human prion disease / Jonathan D.F. Wadsworth ... [et al.] -- Analysis of endogenous PrPc processing in neuronal and non-neuronal cell lines / Victoria Lewis and Steven J. Collins -- Molecular typing of PrPres in human sporadic CJD brain tissue / Victoria Lewis ... [et al.] -- Transgenic mouse models of prion diseases / Glenn C. Telling -- Quantitiative bioassay of surface-bound prion infectivity / Victoria A. Lawson
    Additional Edition: ISBN 9781597452342
    Additional Edition: Erscheint auch als Online-Ausgabe Hill, Andrew F. Prion Protein Protocols Totowa, NJ : Humana Press, 2008 ISBN 9781597452342
    Language: English
    Subjects: Biology
    RVK:
    WC 2000
    Keywords: Prion ; Proteine ; Prion ; Cytologie ; Aufsatzsammlung
    URL: Cover
    URL: Inhaltsverzeichnis
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  • 8
    Book
    Book
    What's wrong with parliament? / (1964)
    Harmondsworth :Penguin Books,
    Details
    UID:
    almafu_BV005244555
    Format: 102 S.
    Series Statement: Penguin special. S230.
    Language: English
    Subjects: Political Science
    RVK:
    MG 42500
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  • 9
    Online Resource
    Online Resource
    Psychology of perfectionism in sport, dance, and exercise / (2023)
    Abingdon, Oxon ; : Routledge,
    Details
    UID:
    almahu_9949530804402882
    Format: 1 online resource
    Edition: Second edition.
    ISBN: 9781003288015 , 1003288014 , 9781000898651 , 1000898652 , 9781000898705 , 1000898709
    Content: "This extensively revised and updated edition offers a comprehensive account of the latest research and practice issues relating to perfectionism in sport, dance, and exercise. The new edition of The Psychology of Perfectionism in Sport, Dance, and Exercise includes the latest understanding of perfectionism, its benefits and costs, and support that can be given to those at risk to the perils of perfectionism. The book features contributions from leading researchers and practitioners. With 9 new chapters and 6 updated chapters, the book provides an exhaustive account of research, novel approaches to studying and working with perfectionism, along with critical reflections on key issues and controversies. The book includes a new section on emerging approaches and concepts, as well as a revised section on applied issues and practitioner perspectives offering 3 new approaches to working with perfectionism. With chapters featuring returning authors and new contributors with novel perspectives, this edition will be invaluable to individuals familiar and unfamiliar with this area of work"--
    Additional Edition: Print version: Psychology of perfectionism in sport, dance, and exercise Abingdon, Oxon ; New York, NY : Routledge, 2023 ISBN 9781032263786
    Language: English
    DOI: 10.4324/9781003288015
    URL: https://www.taylorfrancis.com/books/9781003288015
    URL: lizenzpflichtig
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  • 10
    Book
    Book
    Malachi : a new translation with introduction and commentary (1998)
    New York [u.a.] :Doubleday,
    Details
    UID:
    almahu_BV037239524
    Format: XLIII, 436 S. : Kt.
    Edition: 1. ed.
    ISBN: 0-385-46892-X
    Series Statement: The Anchor Bible 25,D
    Language: English
    Subjects: Theology
    RVK:
    BC 5100
    Keywords: Bibel Maleachi ; Kommentar ; Kommentar ; Kommentar
    URL: http://www.loc.gov/catdir/description/random042/96050480.html
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