UID:
almafu_9958068615502883
Format:
1 online resource (159 p.)
ISBN:
1-280-94098-0
,
9786610940981
,
3-318-01399-4
Series Statement:
Issues in infectious diseases, v. 5
Content:
〈i〉Wolbachia〈/i〉 are Gram-negative bacteria that form intracellular inherited infections in many invertebrates. They are extremely common, with 20-75% of all insects being infected. Moreover, they infect numerous noninsect invertebrates including nematodes, mites and spiders. Approximately 120 million people are infected by filarial nematode parasites worldwide. Transmitted to humans through mosquitoes and black flies, the majority of the disease-causing nematodes are hosts to the 〈i〉Wolbachia〈/i〉 bacteria. These nematodes cause the often devastating diseases elephantiasis and onchocerciasis, commonly referred to as filariasis. Moreover, heartworm disease, caused by another 〈i〉Wolbachia〈/i〉-containing nematode, is another mosquito-borne disease that has significant importance in the veterinary field. Featuring the findings of internationally recognized experts in infectious disease research and insect biology, this publication highlights their perspectives on 〈i〉Wolbachia〈/i〉’s genome, evolution, symbiosis, biology, pathogenicity as well as its potential as a drug target. This comprehensive publication is intended for readers with teaching or research interests in microbiology, entomology, infectious diseases, genetics, tropical medicine and clinical research.
Note:
Description based upon print version of record.
,
""Cover""; ""Contents""; ""Foreword""; ""The Discovery of Wolbachia in Arthropods and Nematodes -- A Historical Perspective""; ""Abstract""; ""Acknowledgements""; ""References""; ""Wolbachia: Evolutionary Significance in Nematodes""; ""Abstract""; ""Phylogeny of Wolbachia in Filarial Nematodes""; ""Wolbachia Distribution in Filarial Nematodes""; ""The Symbiosis between Wolbachia and Its Hosts""; ""The Biology of Wolbachia in Filarial Nematodes""; ""Localization and Population Dynamics of Wolbachia in Filarial Nematodes""; ""Antibiotic Treatments on Wolbachia Hosts""
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""Evidence from Wolbachia Molecular Evolution and Genomics""""References""; ""Wolbachia Endosymbionts: An Achilles� Heel of Filarial Nematodes""; ""Abstract""; ""Biology of Filarial Infections""; ""Past and Current Control Efforts""; ""Wolbachia, Targets for a Novel Chemotherapy against Filariasis""; ""Wolbachia Are Vital to the Biology of Filarial Worms""; ""Wolbachia Are Strong Inducers of the Immune Response""; ""Wolbachia Contribute to the Adverse Reactions Seen after Microfilaricidal Treatment""; ""Antiwolbachial Treatment: A New Tool against Human Filariasis""; ""Conclusion""
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""References""""It Takes Two: Lessons From the First Nematode Wolbachia Genome Sequence""; ""Abstract""; ""References""; ""Coexist, Cooperate and Thrive: Wolbachia as LongH Term Symbionts of Filarial Nematodes""; ""Abstract""; ""Wolbachia as a Mutualistic Partner""; ""On the Origins of Wolbachia""; ""Gene Loss and Metabolic Dependency in Long Associations: Why Do Wolbachia Need Nematodes?""; ""Why Do Filarial Nematodes Need Wolbachia: Vitamins and Smokescreens?""; ""Cementing the Wolbachia -Nematode Relationship with Molecular Glue""; ""Are Filarial Wolbachia Really Obligate Mutualists?""
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""Evidence of Absence: Horizontal Gene Exchange between Wolbachia and Nematode Genomes""""References""; ""Insights into Wolbachia Biology Provided through Genomic Analysis""; ""Abstract""; ""Genome Features of Wolbachia""; ""Genome Rearrangements""; ""Mobile DNA""; ""Transposable Elements""; ""Prophage""; ""Wolbachia Genomics and Population Biology""; ""Nonneutral Evolution in Wolbachia Genomes""; ""The Synthesis of Cofactors""; ""Secretion""; ""Replication""; ""Protein Stability""; ""References""; ""Wolbachia Symbiosis in Arthropods""; ""Abstract""
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""Phenotypic Effects of Wolbachia on Their Hosts""""Feminization""; ""Parthenogenesis""; ""Male Killing""; ""Cytoplasmic Incompatibility""; ""The Cellular Biology of CI""; ""CI and Speciation""; ""Models of CI""; ""Other Wolbachia-Induced Phenotypes?""; ""Novelty and Ancestry?""; ""Feminization""; ""Parthenogenesis""; ""Male Killing""; ""Cytoplasmic Incompatibility""; ""Wolbachia-Host Interactions""; ""Spermatogenesis""; ""Wolbachia in Oogenesis and Embryogenesis""; ""Oogenesis""; ""Embryogenesis""; ""Conclusions""; ""References""; ""Wolbachia and Its Importance in Veterinary Filariasis""
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""Abstract""
,
English
Additional Edition:
ISBN 3-8055-8180-7
Language:
English
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