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  • 1
    Online Resource
    Online Resource
    Berlin [u.a.] : Springer
    UID:
    b3kat_BV036650721
    Format: 1 Online-Ressource
    Edition: Online-Ausgabe Springer ebook collection / Chemistry and Materials Science 2005-2008 Sonstige Standardnummer des Gesamttitels: 041171-1
    ISBN: 9783540340072
    Series Statement: Advances in Biochemical Engineering, Biotechnology 101
    Additional Edition: Reproduktion von Cell Culture Engineering 2006
    Additional Edition: Erscheint auch als Druckausgabe ISBN 978-3-540-34006-5
    Language: English
    Subjects: Biology
    RVK:
    RVK:
    Keywords: Zellkultur ; Biotechnologie ; Aufsatzsammlung ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    Author information: Hu, Wei-Shou 1951-
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Book
    Book
    Berlin ; Heidelberg :Springer,
    UID:
    almahu_BV039961151
    Format: XXII, 288 S.
    ISBN: 3-642-28349-7 , 978-3-642-28349-9
    Series Statement: Advances in biochemical engineering biotechnology 127
    Additional Edition: Erscheint auch als Online-Ausgabe ISBN 978-3-642-28350-5
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Zellkultur ; Säugetiere ; Systembiologie ; Aufsatzsammlung
    Author information: Hu, Wei-Shou 1951-
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Online Resource
    Online Resource
    Boca Raton, FL :CRC Press, Taylor & Francis Group,
    UID:
    almahu_9949385800102882
    Format: 1 online resource : , illustrations
    Edition: Second edition.
    ISBN: 9780429162770 , 9780429546594 , 0429546599 , 0429162774 , 9781498762861 , 1498762867 , 9780429531897 , 0429531893
    Content: "This reference guide is designed for industrial practitioners of mammalian cell cultivation for the production of biologics. This work is a culmination of two decades of accumulated expertise, practical know-how and best practices in cell culture technology. The Second Edition consists of major updates to all relevant topics contained within this work"--
    Note: Overview of Cell Culture Processes -- Cell Biology for Bioprocessing -- Cell Physiology -- Product Quality and Process -- Stoichiometry and the Kinetics of Cell Cultivation -- Cell Line Development -- Medium Design for Cell Culture Processing -- Cell Culture Bioreactors -- Fed-Batch Culture Processes -- Continuous Cell Culture Processes -- Oxygen Transfer in Cell Culture Bioreactors -- Scaling Up and Scaling Down for Cell Culture Bioreactors.
    Additional Edition: Print version: Hu, Wei-Shou, 1951- Cell culture bioprocess engineering. Boca Raton, FL : CRC Press, Taylor & Francis Group, [2020] ISBN 9780429546594
    Language: English
    Keywords: Electronic books. ; Electronic books.
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    UID:
    b3kat_BV039961151
    Format: XXII, 288 S.
    ISBN: 3642283497 , 9783642283499
    Series Statement: Advances in biochemical engineering biotechnology 127
    Additional Edition: Erscheint auch als Online-Ausgabe ISBN 978-3-642-28350-5
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Zellkultur ; Säugetiere ; Systembiologie ; Aufsatzsammlung
    Author information: Hu, Wei-Shou 1951-
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    Online Resource
    Online Resource
    Berlin ; : Springer-Verlag,
    UID:
    edoccha_9958073728102883
    Format: 1 online resource (178 p.)
    Edition: 1st ed. 2006.
    ISBN: 1-280-61552-4 , 9786610615520
    Series Statement: Advances in Biochemical Engineering/Biotechnology
    Content: Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.
    Note: Description based upon print version of record. , Established Bioprocesses for Producing Antibodies as a Basis for Future Planning -- Fedbatch Culture and Dynamic Nutrient Feeding -- The “Push-to-Low” Approach for Optimization of High-Density Perfusion Cultures of Animal Cells -- Towards Industrial Application of Quasi Real-Time Metabolic Flux Analysis for Mammalian Cell Culture -- Engineering Cells for Cell Culture Bioprocessing – Physiological Fundamentals. , English
    Additional Edition: ISBN 3-540-34006-8
    Additional Edition: ISBN 3-540-34007-6
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 6
    Online Resource
    Online Resource
    Berlin ; : Springer-Verlag,
    UID:
    edocfu_9958073728102883
    Format: 1 online resource (178 p.)
    Edition: 1st ed. 2006.
    ISBN: 1-280-61552-4 , 9786610615520
    Series Statement: Advances in Biochemical Engineering/Biotechnology
    Content: Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.
    Note: Description based upon print version of record. , Established Bioprocesses for Producing Antibodies as a Basis for Future Planning -- Fedbatch Culture and Dynamic Nutrient Feeding -- The “Push-to-Low” Approach for Optimization of High-Density Perfusion Cultures of Animal Cells -- Towards Industrial Application of Quasi Real-Time Metabolic Flux Analysis for Mammalian Cell Culture -- Engineering Cells for Cell Culture Bioprocessing – Physiological Fundamentals. , English
    Additional Edition: ISBN 3-540-34006-8
    Additional Edition: ISBN 3-540-34007-6
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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