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  • 1
    Online Resource
    Online Resource
    Totowa, NJ : Humana Press
    UID:
    b3kat_BV036650549
    Format: 1 Online-Ressource , v.: digital
    Edition: Online_Ausgabe Totowa, NJ Humana Press 2008 Springer ebook collection / Chemistry and Materials Science 2005-2008 Sonstige Standardnummer des Gesamttitels: 041171-1
    ISBN: 9781603273183 , 9781603273190
    Additional Edition: Reproduktion von The Handbook of Nanomedicine 2008
    Language: English
    Subjects: Engineering , Medicine
    RVK:
    RVK:
    Keywords: Klinische Medizin ; Nanobiotechnologie ; Medizin ; Nanotechnologie
    URL: Volltext  (lizenzpflichtig)
    Author information: Jain, Kewal K. 1937-
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    New York, NY :Springer New York,
    UID:
    almafu_BV044529765
    Format: 1 Online-Ressource (XIV, 760 p. 16 illus., 2 illus. in color).
    Edition: 2nd ed. 2017
    ISBN: 978-1-4939-7431-3
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-1-4939-7430-6
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing, | Cham :Springer.
    UID:
    almafu_BV047094256
    Format: 1 Online-Ressource (XLIII, 744 p. 41 illus., 5 illus. in color).
    Edition: 3rd ed. 2021
    ISBN: 978-3-030-62080-6
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-62079-0
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-62081-3
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-62082-0
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Pharmakogenetik ; Individualisierte Medizin
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 4
    Online Resource
    Online Resource
    New York, NY :Springer New York,
    UID:
    almafu_BV044256858
    Format: 1 Online-Ressource (XVIII, 659 p. 23 illus., 15 illus. in color).
    Edition: 3rd ed. 2017
    ISBN: 978-1-4939-6966-1
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-1-4939-6965-4
    Language: English
    Subjects: Engineering , Medicine
    RVK:
    RVK:
    Keywords: Klinische Medizin ; Nanobiotechnologie ; Medizin ; Nanotechnologie
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (URL des Erstveröffentlichers)
    Author information: Jain, Kewal K. 1937-
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  • 5
    Online Resource
    Online Resource
    New York, NY :Springer New York :
    UID:
    almahu_9949251357102882
    Format: 1 online resource (XII, 158 p. 17 illus., 6 illus. in color.)
    Edition: 1st ed. 2015.
    ISBN: 1-4939-2247-5
    Series Statement: Neuromethods, 97
    Content: This detailed volume reflects the considerable new developments that have taken place in the area of applied neurogenomics, particularly with the rapid progress in next generation sequencing. Beginning with an introduction to the technologies relevant to neurogenomics with an emphasis on next generation sequencing, the book also covers detailed methods relevant to the genomics of neurodegenerative diseases, particularly Alzheimer’s disease and Huntington’s disease, targeted sequencing of psychiatric disorders, as well as the role of genomics in the development of personalized neurology. Written in the popular Neuromethods series format, chapters provide the kind of practical description and implementation advice necessary to consistently produce successful results in the lab. Timely and convenient, Applied Neurogenomics serves as an invaluable reference for researchers working in this expanding, dynamic field.
    Note: Bibliographic Level Mode of Issuance: Monograph , An Overview of Methods Used in Neurogenomics and Their Applications -- Gene Expression-Based Approaches to Understanding Huntington’s Disease and New Tools for the Interpretation of Expression Datasets -- Location Analysis and Expression Profiling Using Next Generation Sequencing for Research in Neurodegenerative Diseases -- RNA Sequencing from Laser Capture Microdissected Brain Tissue to Study Normal Aging and Alzheimer’s Disease -- Targeted Re-Sequencing in Psychiatric Disorders -- Role of Neurogenomics in the Development of Personalized Neurology. , English
    Additional Edition: ISBN 1-4939-2246-7
    Language: English
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  • 6
    Online Resource
    Online Resource
    New York, NY :Springer New York :
    UID:
    almahu_9949251320702882
    Format: 1 online resource (XI, 280 p. 78 illus., 51 illus. in color.)
    Edition: 2nd ed. 2014.
    ISBN: 1-4939-0363-2
    Series Statement: Methods in Molecular Biology, 1141
    Content: Drug Delivery Systems, Second Edition expands upon the previous edition with current, detailed methods and technologies to further study drug delivery. With new chapters on nanobiotechnology techniques, experimental methods, and the clinical use for the intrathecal delivery of analgesics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Drug Delivery Systems, Second Edition will be useful for pharmaceutical scientists as well as well as physicians both in the academic institutions and in the industry.
    Note: Bibliographic Level Mode of Issuance: Monograph , Current Status and Future Prospects of Drug Delivery Systems -- A Method for Screening Mitochondrial Fusogenic Envelopes for use in Mitochondrial Drug Delivery -- Ultrasound-directed, Site-specific Gene Delivery -- Synthesis of Thermoresponsive Polymers for Drug Delivery -- Recombinant Stem Cells as Carriers for Cancer Gene Therapy -- Microfluidic-based Manufacture of siRNA-lipid Nanoparticles for Therapeutic Applications -- Microneedle-iontophoresis Combinations for Enhanced Transdermal Drug Delivery -- Polymer Nanoparticle-based Controlled Pulmonary Drug Delivery -- Antibody Labeling with Radioiodine and Radiometals -- Self Assembling Peptide -based Delivery of Therapeutics for Myocardial Infarction -- Applications of Chitosan Nanoparticles in Drug Delivery -- A Method for Evaluating Nanoparticle Transport through the Blood Brain Barrier in vitro -- Bacterial Systems for Gene Delivery to Systemic Tumours -- Synthesis of a Smart Nanovehicle for Targeting Liver -- Intranasal Delivery of Chitosan-siRNA Nanoparticle Formulation to the Brain -- Intrathecal Delivery of Analgesics. , English
    Additional Edition: ISBN 1-4939-0362-4
    Language: English
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  • 7
    Online Resource
    Online Resource
    New York, NY :Springer New York :
    UID:
    almahu_9949251524502882
    Format: 1 online resource (XI, 316 p. 54 illus., 36 illus. in color.)
    Edition: 3rd ed. 2020.
    ISBN: 1-4939-9798-X
    Series Statement: Methods in Molecular Biology, 2059
    Content: This third edition volume expands on the previous editions with a discussion of new and updated methods used to study drug delivery. Chapters cover topics such as drug delivery in cancer and intrathecal delivery of analgesics in humans. The increasing role of nanobiotechnology is reflected in eight of the sixteen chapters that include synthesis of gold nanoparticles; targeted siRNA delivery; and lipid nanocarriers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Drug Delivery Systems: Methods and Protocols, Third Edition is a valuable resource for scientists working in industry or academia, and physicians involved in research and clinical care of patients.
    Note: An Overview of Drug Delivery Systems -- Role of Nanobiotechnology in Drug Delivery -- Intrathecal Drug Delivery -- Microanatomy Relevant to Intrathecal Drug Delivery -- Drug Delivery Applications of Nanoparticles in the Spine -- Synthesis of Gold Nanoparticle: Peptide Drug Conjugates for Targeted Drug Delivery -- A Method for Targeted Non-Viral siRNA Delivery in Cancer and Inflammatory Diseases -- Tumor-Targeted Dendrimer Nanoparticles for Combinatorial Delivery of siRNA and Chemotherapy for Cancer Treatment -- Sonoporation for augmenting Chemotherapy of Pancreatic Ductal Adenocarcinoma -- Preparation of Cholera Toxin Subunit B Functionalized Nanoparticles for Targeted Therapy of Glioblastoma -- Microfluidic-Manufacturing of Multi-Targeted PLGA/PEG Nanoparticles for Delivery of Taxane Chemotherapeutics -- Computer-Aided Design of Nanoparticles for Transdermal Drug Delivery -- Microneedle Mediated Transdermal Delivery of Tizanidine Hydrochloride -- Targeted siRNA Delivery using Lipid Nanoparticles -- Lipid Nanocarriers for Enhanced Delivery of Temosolomide to the Brain -- Construction of a Macrophage-Targeting Bio-Nanocapsule-Based Nanocarrier. .
    Additional Edition: ISBN 1-4939-9797-1
    Language: English
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  • 8
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press :
    UID:
    almahu_9949251535202882
    Format: 1 online resource (X, 251 p. 55 illus.)
    Edition: 1st ed. 2008.
    ISBN: 1-59745-210-6
    Series Statement: Methods in Molecular Biology, 437
    Content: The field of drug development and therapeutics can be overwhelmingly encyclopedic and vast. In Drug Delivery Systems, Dr. Kewal Jain and a team of experts select the most important, cutting-edge technologies used in drug delivery systems taking into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular Biology™ series format, offering readily reproducible results vital for pharmaceutical physicians and scientists. Concise and systematic, Drug Delivery Systems is a powerful reference tool for the hundreds of companies developing drug delivery technologies all around the world.
    Note: Bibliographic Level Mode of Issuance: Monograph , Drug Delivery Systems - An Overview -- The Role of the Adeno-Associated Virus Capsid in Gene Transfer -- Delivering Small Interfering RNA for Novel Therapeutics -- Catheters for Chronic Administration of Drugs into Brain Tissue -- Transdermal Drug Delivery Systems: Skin Perturbation Devices -- Controlling the Release of Proteins/Peptides via the Pulmonary Route -- Engineering Protein Particles for Pulmonary Drug Delivery -- 2B-Trans™ Technology: Targeted Drug Delivery Across the Blood-Brain Barrier -- Drug Delivery in Cancer Using Liposomes -- pH-Responsive Nanoparticles for Cancer Drug Delivery -- Extended-Release Oral Drug Delivery Technologies: Monolithic Matrix Systems. , English
    Additional Edition: ISBN 1-61737-828-3
    Additional Edition: ISBN 1-58829-891-4
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 9
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press :
    UID:
    almahu_9949251685602882
    Format: 1 online resource (XII, 324p. 188 illus., 94 illus. in color.)
    Edition: 1st ed. 2010.
    ISBN: 1-60761-529-0
    Series Statement: Neuromethods, 45
    Content: Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.
    Note: Bibliographic Level Mode of Issuance: Monograph , An Overview of Drug Delivery to the CNS -- Receptor-Mediated Transport of Drugs Across the BBB -- Disruption of Blood–Brain Barrier by Focused Ultrasound for Targeted Drug Delivery to the Brain -- Prediction of Blood–Brain Barrier Penetration by Drugs -- Intraparenchymal Delivery and Its Discontents -- Intrathecal Drug Delivery by Implanted Pumps -- Intracarotid Drug Delivery: Revisiting the Past or Looking into the Future -- Vesicular Systems for Intranasal Drug Delivery -- Convection-Enhanced Drug Delivery and Monitoring in a Rat Model -- Intrathecal Delivery of Stem Cells to the Spinal Cord -- CNS Delivery of Peptides Across the BBB Using the Dual-Artery In Situ Brain Perfusion Model -- An Engineered Peptide Compound Platform Technology Incorporating Angiopep for Crossing the BBB -- Adeno-Associated Virus Mediated Gene Therapy in Ischemic Stroke -- Use of Mesenchymal Stem Cells for Gene Delivery to Intracranial Glioma -- Convection-Enhanced Drug Delivery to the Brain. , English
    Additional Edition: ISBN 1-60761-528-2
    Language: English
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  • 10
    Online Resource
    Online Resource
    New York, NY :Springer New York :
    UID:
    almahu_9949251530402882
    Format: 1 online resource (865 pages)
    Edition: 2nd ed. 2019.
    ISBN: 1-4939-9465-4
    Content: This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment. Since the publication of the first edition, advances in biotechnology, particularly in cell and gene therapies, are reflected in this volume, as are numerous new and repurposed drugs in clinical trials. Overall, The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of disorders of the central nervous system. In-depth and authoritative, The Handbook of Neuroprotection, Second Edition features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.
    Note: Introduction -- Neuroprotective Agents -- Neuroprotection in Cerebrovascular Disease -- Neuroprotection in Traumatic Brain Injury -- Neuroprotection in Spinal Cord Injury -- Neuroprotection in Neurodegenerative Disorders -- Neuroprotection in Parkinson Disease -- Neuroprotection in Alzheimer Disease -- Neuroprotection in Huntington Disease -- Neuroprotection in Amyotrophic Lateral Sclerosis -- Neuroprotection in Miscellaneous Neurological Disorders -- Neuroprotection of the Optic nerve and the Retina -- Neuroprotection during Anesthesia and Surgery. .
    Additional Edition: ISBN 1-4939-9464-6
    Language: English
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