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  • 1
    Online Resource
    Online Resource
    Endocrinology : Adult and Pediatric (2010)
    St. Louis :Elsevier Health Sciences,
    Details
    UID:
    almahu_9949225678902882
    Format: 1 online resource (3076 p.)
    Edition: 6th ed.
    ISBN: 0-323-24062-3 , 0-323-22155-6 , 0-323-22153-X , 1-4557-1126-8
    Note: Description based upon print version of record. , ""Volume 1""; ""Front cover""; ""Half title page ""; ""Title page""; ""Copyright page""; ""Contributors""; ""Preface""; ""Table of contents""; ""Color plate""; ""PART 1: Principles of Endocrinology and Hormone Signaling""; ""Chapter 1: ENDOCRINOLOGY: Impact on Science and Medicine""; ""Definition and Scope of Endocrinology""; ""Historical Perspectives""; ""Principles of Hormone Action""; ""Hormone Action Through Receptors""; ""Role of the Clinical Endocrinologist""; ""Major Unsolved Problems""; ""REFERENCES""; ""Chapter 2: CONTROL OF HORMONE GENE EXPRESSION"" , ""The Central Dogma of Molecular Biology Revisited""""Chromatin: Accessibility of DNA to Control Factors""; ""Functional Anatomy of a Gene""; ""Functional Anatomy of the Promoter-Regulatory Region""; ""Transcription: Creating the Template for Protein Synthesis""; ""Posttranscriptional Modification of mRNA""; ""Translation: Regulated Protein Biosynthesis""; ""Posttranslational Modifications""; ""Regulated Secretion of Proteins""; ""RNAi Regulation of Gene Expression""; ""Hormonal Control of Gene Expression""; ""Functional Genomics and Proteomics""; ""REFERENCES""; ""BIBLIOGRAPHY"" , ""Chapter 3: CONTROL OF HORMONE SECRETION""""Morphology of Peptide Hormone�Secreting Endocrine Cells and the Regulated Secretory Pathway""; ""Synthesis, Processing, and Sorting of Preprohormone Precursors""; ""Composition of Mature Secretory Granules""; ""Sequential Stages of the Regulated Secretory Pathway""; ""Essential Protein Machinery for Dense-Core Granule Exocytosis""; ""Regulation of Exocytosis by Calcium""; ""Modulation of Calcium-Dependent Hormone Secretion by Protein Kinase C""; ""REFERENCES""; ""Chapter 4: INSULIN AND GROWTH FACTOR SIGNALING PATHWAYS"" , ""Receptor Tyrosine Kinases""""History""; ""Receptor Tyrosine Kinase Subfamilies""; ""Ligand Binding""; ""Mechanism of RTK Signaling""; ""Insulin/Mitogen Activation of Ser/Thr Phosphorylation-I: Signaling Downstream of PI-3-Kinase""; ""Mammalian Target of Rapamycin: A Central Regulator of Protein Synthesis in Insulin/Mitogen and Nutrient-Sensing Pathways""; ""Insulin/Mitogen Activation of Ser/Thr Phosphorylation-II: Signaling Through Ras and the MAP Kinases""; ""Additional Mammalian MAPKs and MAPK Pathways""; ""REFERENCES""; ""Chapter 5: HORMONE SIGNALING VIA G PROTEIN�COUPLED RECEPTORS"" , ""Classification of G Protein�Coupled Receptors""""Structural Features of G Protein�Coupled Receptors""; ""Posttranslational Modifications""; ""Diversity of Receptor-Ligand Binding""; ""Mechanism of Receptor Activation""; ""Receptor/G Protein Coupling and Selectivity""; ""G Protein�Dependent Effectors""; ""G Protein�Coupled Receptor Signaling Networks""; ""G Protein�Coupled Receptor Interacting Proteins""; ""G Protein�Coupled Receptor Dimerization""; ""Mechanisms of G Protein�Coupled Receptor Desensitization""; ""G Protein�Coupled Receptor Signaling and Disease"" , ""Acknowledgments"" , English
    Additional Edition: ISBN 1-336-24443-7
    Additional Edition: ISBN 1-4160-5583-5
    Language: English
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  • 2
    Online Resource
    Online Resource
    Endocrinology : adult & pediatric (2016)
    Philadelphia, Pennsylvania :Saunders/Elsevier,
    Details
    UID:
    almahu_9949697331902882
    Format: 1 online resource (3707 p.)
    Edition: 7th ed.
    ISBN: 0-323-32195-X , 0-323-18907-5
    Uniform Title: Endocrinology (DeGroot)
    Note: Description based upon print version of record. , e9780323189071v1; Front Cover; IFC; Endocrinology; Copyright; CONTRIBUTORS; PREFACE; CONTENTS; Part-01 - Principles of Endocrinology and Hormone Signaling ; chapter 1 - Principles of Endocrinology; DEFINITION AND SCOPE OF ENDOCRINOLOGY; HISTORICAL PERSPECTIVES; PRINCIPLES OF HORMONE ACTION; HORMONE ACTION THROUGH RECEPTORS; ROLE OF THE CLINICAL ENDOCRINOLOGIST; MAJOR UNSOLVED PROBLEMS; REFERENCES; CHAPTER 2 - CONTROL OF HORMONE GENE EXPRESSION; CHROMATIN: ACCESSIBILITY OF DNA TO CONTROL FACTORS; FUNCTIONAL ANATOMY OF A GENE; FUNCTIONAL ANATOMY OF THE PROMOTER-REGULATORY REGION , TRANSCRIPTION: CREATING THE TEMPLATE FOR PROTEIN SYNTHESISPOSTTRANSCRIPTIONAL MODIFICATION OF MRNA; TRANSLATION: REGULATED PROTEIN BIOSYNTHESIS; POSTTRANSLATIONAL MODIFICATIONS; REGULATED SECRETION OF PROTEINS; RNAI REGULATION OF GENE EXPRESSION; HORMONAL CONTROL OF GENE EXPRESSION; FUNCTIONAL GENOMICS AND PROTEOMICS; REFERENCES; CHAPTER 3 - CONTROL OF HORMONE SECRETION; SYNTHESIS, PROCESSING, AND SORTING OF PREPROHORMONE PRECURSORS; COMPOSITION OF MATURE SECRETORY GRANULES; SEQUENTIAL STAGES OF THE REGULATED SECRETORY PATHWAY; ESSENTIAL PROTEIN MACHINERY FOR DENSE-CORE GRANULE EXOCYTOSIS , REGULATION OF EXOCYTOSIS BY CALCIUMMODULATION OF CALCIUM-DEPENDENT HORMONE SECRETION BY PROTEIN KINASE C; REFERENCES; chapter 4 - Applications of Genetics in Endocrinology; THE HUMAN GENOME PROJECT AND ITS IMPACT ON MEDICINE; STRUCTURE OF THE HUMAN GENOME; CATEGORIES OF GENETIC DISORDERS; RELATIONSHIP BETWEEN GENOTYPE AND PHENOTYPE IN GENETIC DISORDERS; VARIATIONS IN SIMPLE MENDELIAN INHERITANCE PATTERNS; PRINCIPLES OF GENETIC LINKAGE AND ASSOCIATION; METHODS USED TO DETECT GENE DELETIONS AND POINT MUTATIONS; OVERVIEW OF INHERITED ENDOCRINE DISORDERS; APPROACH TO THE PATIENT , CURRENT DEVELOPMENTSREFERENCES; Part-02 - Neuroendocrinology and Pituitary Disease ; CHAPTER 5 - DEVELOPMENT OF THE PITUITARY*; PITUITARY DEVELOPMENT; TRANSCRIPTION FACTORS AND PITUITARY DEVELOPMENT; OTHER TRANSCRIPTION FACTORS; SIGNALING PATHWAYS IN PITUITARY DEVELOPMENT; NOTCHS; INTERACTIONS BETWEEN DIFFERENT MORPHOGENIC FACTORS; INDEPENDENT HH AND FGF SIGNALING IN PITUITARY ORGANOGENESIS; PITUITARY AND EPIGENETICS; STEM CELLS; SUMMARY; REFERENCES; chapter 6 - Prolactin; THE EVOLUTIONARY BIOLOGY OF PROLACTIN; THE BIOCHEMISTRY OF PROLACTIN , THE ONTOGENY AND PHYSIOLOGY OF PROLACTIN SECRETIONPATHOPHYSIOLOGY OF PROLACTIN SECRETION; PROLACTIN RECEPTORS AND SIGNAL TRANSDUCTION; THE PHYSIOLOGY AND PATHOPHYSIOLOGY OF PROLACTIN ACTIONS IN MAMMALS; SUMMARY; REFERENCES; CHAPTER 7 - DISORDERS OF PROLACTIN SECRETION AND PROLACTINOMAS; EPIDEMIOLOGY; PATHOGENESIS; PATHOLOGY; DIFFERENTIAL DIAGNOSIS OF HYPERPROLACTINEMIA; DIAGNOSIS OF PROLACTINOMAS; TREATMENT; REFERENCES; chapter 8 - Adrenocorticotropic Hormone; HISTORY; PROOPIOMELANOCORTIN GENE; ADRENOCORTICOTROPIC HORMONE AND RELATED PEPTIDES; REFERENCES , chapter 9 - Endocrine Rhythms, the Sleep-Wake Cycle, and Biological Clocks , English
    Language: English
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    HU Berlin
    FU Berlin
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  • 3
    Online Resource
    Online Resource
    Endocrinology : adult & pediatric (2016)
    Philadelphia, PA :Elsevier/Saunders,
    Details
    UID:
    almafu_BV043216307
    Format: 1 Online-Ressource.
    Edition: 7th edition
    ISBN: 978-0-323-18907-1 , 0-323-18907-5 , 978-0-323-18907-1 , 978-0-323-32195-2 , 0-323-32195-X
    Uniform Title: Endocrinology (DeGroot)
    Note: Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. - Includes bibliographical references and index
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (URL des Erstveröffentlichers)
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    Online Access
    FU Berlin
    Charité
  • 4
    Book
    Book
    Principles of molecular medicine (1998)
    Totowa, N.J. : Humana Press
    Details
    UID:
    gbv_244209529
    Format: XIX, 1123 S. , Ill., graph. Darst. , 29 cm
    ISBN: 0896035298
    Series Statement: Internal medicine
    Note: Literaturangaben
    Language: English
    Subjects: Biology
    RVK:
    WG 7000
    Keywords: Humangenetik ; Pathomechanismus ; Molekularpathologie ; Aufsatzsammlung
    URL: Inhaltsverzeichnis
    Author information: Collins, Francis S. 1950-
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  • 5
    Book
    Book
    Harrison's endocrinology (2006)
    New York, NY [u.a.] : McGraw-Hill
    Details
    UID:
    gbv_505175177
    Format: X, 563 S , Ill., graph. Darst , 28 cm
    Edition: [16. ed.]
    ISBN: 0071457445
    Note: Früher u.d.T.: Harrison's principles of internal medicine , Includes bibliographical references and index
    Language: English
    Keywords: Endokrinologie ; Endokrinopathie ; Stoffwechselkrankheit
    URL: http://www.loc.gov/catdir/enhancements/fy0626/2005058005-b.html
    URL: http://www.loc.gov/catdir/enhancements/fy0626/2005058005-d.html
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  • 6
    Online Resource
    Online Resource
    Endocrinology : adult & pediatric (2016)
    Philadelphia, Pennsylvania :Saunders/Elsevier,
    Details
    UID:
    edoccha_9958072848802883
    Format: 1 online resource (3707 p.)
    Edition: 7th ed.
    ISBN: 0-323-32195-X , 0-323-18907-5
    Uniform Title: Endocrinology (DeGroot)
    Note: Description based upon print version of record. , e9780323189071v1; Front Cover; IFC; Endocrinology; Copyright; CONTRIBUTORS; PREFACE; CONTENTS; Part-01 - Principles of Endocrinology and Hormone Signaling ; chapter 1 - Principles of Endocrinology; DEFINITION AND SCOPE OF ENDOCRINOLOGY; HISTORICAL PERSPECTIVES; PRINCIPLES OF HORMONE ACTION; HORMONE ACTION THROUGH RECEPTORS; ROLE OF THE CLINICAL ENDOCRINOLOGIST; MAJOR UNSOLVED PROBLEMS; REFERENCES; CHAPTER 2 - CONTROL OF HORMONE GENE EXPRESSION; CHROMATIN: ACCESSIBILITY OF DNA TO CONTROL FACTORS; FUNCTIONAL ANATOMY OF A GENE; FUNCTIONAL ANATOMY OF THE PROMOTER-REGULATORY REGION , TRANSCRIPTION: CREATING THE TEMPLATE FOR PROTEIN SYNTHESISPOSTTRANSCRIPTIONAL MODIFICATION OF MRNA; TRANSLATION: REGULATED PROTEIN BIOSYNTHESIS; POSTTRANSLATIONAL MODIFICATIONS; REGULATED SECRETION OF PROTEINS; RNAI REGULATION OF GENE EXPRESSION; HORMONAL CONTROL OF GENE EXPRESSION; FUNCTIONAL GENOMICS AND PROTEOMICS; REFERENCES; CHAPTER 3 - CONTROL OF HORMONE SECRETION; SYNTHESIS, PROCESSING, AND SORTING OF PREPROHORMONE PRECURSORS; COMPOSITION OF MATURE SECRETORY GRANULES; SEQUENTIAL STAGES OF THE REGULATED SECRETORY PATHWAY; ESSENTIAL PROTEIN MACHINERY FOR DENSE-CORE GRANULE EXOCYTOSIS , REGULATION OF EXOCYTOSIS BY CALCIUMMODULATION OF CALCIUM-DEPENDENT HORMONE SECRETION BY PROTEIN KINASE C; REFERENCES; chapter 4 - Applications of Genetics in Endocrinology; THE HUMAN GENOME PROJECT AND ITS IMPACT ON MEDICINE; STRUCTURE OF THE HUMAN GENOME; CATEGORIES OF GENETIC DISORDERS; RELATIONSHIP BETWEEN GENOTYPE AND PHENOTYPE IN GENETIC DISORDERS; VARIATIONS IN SIMPLE MENDELIAN INHERITANCE PATTERNS; PRINCIPLES OF GENETIC LINKAGE AND ASSOCIATION; METHODS USED TO DETECT GENE DELETIONS AND POINT MUTATIONS; OVERVIEW OF INHERITED ENDOCRINE DISORDERS; APPROACH TO THE PATIENT , CURRENT DEVELOPMENTSREFERENCES; Part-02 - Neuroendocrinology and Pituitary Disease ; CHAPTER 5 - DEVELOPMENT OF THE PITUITARY*; PITUITARY DEVELOPMENT; TRANSCRIPTION FACTORS AND PITUITARY DEVELOPMENT; OTHER TRANSCRIPTION FACTORS; SIGNALING PATHWAYS IN PITUITARY DEVELOPMENT; NOTCHS; INTERACTIONS BETWEEN DIFFERENT MORPHOGENIC FACTORS; INDEPENDENT HH AND FGF SIGNALING IN PITUITARY ORGANOGENESIS; PITUITARY AND EPIGENETICS; STEM CELLS; SUMMARY; REFERENCES; chapter 6 - Prolactin; THE EVOLUTIONARY BIOLOGY OF PROLACTIN; THE BIOCHEMISTRY OF PROLACTIN , THE ONTOGENY AND PHYSIOLOGY OF PROLACTIN SECRETIONPATHOPHYSIOLOGY OF PROLACTIN SECRETION; PROLACTIN RECEPTORS AND SIGNAL TRANSDUCTION; THE PHYSIOLOGY AND PATHOPHYSIOLOGY OF PROLACTIN ACTIONS IN MAMMALS; SUMMARY; REFERENCES; CHAPTER 7 - DISORDERS OF PROLACTIN SECRETION AND PROLACTINOMAS; EPIDEMIOLOGY; PATHOGENESIS; PATHOLOGY; DIFFERENTIAL DIAGNOSIS OF HYPERPROLACTINEMIA; DIAGNOSIS OF PROLACTINOMAS; TREATMENT; REFERENCES; chapter 8 - Adrenocorticotropic Hormone; HISTORY; PROOPIOMELANOCORTIN GENE; ADRENOCORTICOTROPIC HORMONE AND RELATED PEPTIDES; REFERENCES , chapter 9 - Endocrine Rhythms, the Sleep-Wake Cycle, and Biological Clocks , English
    Language: English
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    Online Resource
    Charité
  • 7
    Online Resource
    Online Resource
    Endocrinology : adult & pediatric (2016)
    Philadelphia, Pennsylvania :Saunders/Elsevier,
    Details
    UID:
    edocfu_9958072848802883
    Format: 1 online resource (3707 p.)
    Edition: 7th ed.
    ISBN: 0-323-32195-X , 0-323-18907-5
    Uniform Title: Endocrinology (DeGroot)
    Note: Description based upon print version of record. , e9780323189071v1; Front Cover; IFC; Endocrinology; Copyright; CONTRIBUTORS; PREFACE; CONTENTS; Part-01 - Principles of Endocrinology and Hormone Signaling ; chapter 1 - Principles of Endocrinology; DEFINITION AND SCOPE OF ENDOCRINOLOGY; HISTORICAL PERSPECTIVES; PRINCIPLES OF HORMONE ACTION; HORMONE ACTION THROUGH RECEPTORS; ROLE OF THE CLINICAL ENDOCRINOLOGIST; MAJOR UNSOLVED PROBLEMS; REFERENCES; CHAPTER 2 - CONTROL OF HORMONE GENE EXPRESSION; CHROMATIN: ACCESSIBILITY OF DNA TO CONTROL FACTORS; FUNCTIONAL ANATOMY OF A GENE; FUNCTIONAL ANATOMY OF THE PROMOTER-REGULATORY REGION , TRANSCRIPTION: CREATING THE TEMPLATE FOR PROTEIN SYNTHESISPOSTTRANSCRIPTIONAL MODIFICATION OF MRNA; TRANSLATION: REGULATED PROTEIN BIOSYNTHESIS; POSTTRANSLATIONAL MODIFICATIONS; REGULATED SECRETION OF PROTEINS; RNAI REGULATION OF GENE EXPRESSION; HORMONAL CONTROL OF GENE EXPRESSION; FUNCTIONAL GENOMICS AND PROTEOMICS; REFERENCES; CHAPTER 3 - CONTROL OF HORMONE SECRETION; SYNTHESIS, PROCESSING, AND SORTING OF PREPROHORMONE PRECURSORS; COMPOSITION OF MATURE SECRETORY GRANULES; SEQUENTIAL STAGES OF THE REGULATED SECRETORY PATHWAY; ESSENTIAL PROTEIN MACHINERY FOR DENSE-CORE GRANULE EXOCYTOSIS , REGULATION OF EXOCYTOSIS BY CALCIUMMODULATION OF CALCIUM-DEPENDENT HORMONE SECRETION BY PROTEIN KINASE C; REFERENCES; chapter 4 - Applications of Genetics in Endocrinology; THE HUMAN GENOME PROJECT AND ITS IMPACT ON MEDICINE; STRUCTURE OF THE HUMAN GENOME; CATEGORIES OF GENETIC DISORDERS; RELATIONSHIP BETWEEN GENOTYPE AND PHENOTYPE IN GENETIC DISORDERS; VARIATIONS IN SIMPLE MENDELIAN INHERITANCE PATTERNS; PRINCIPLES OF GENETIC LINKAGE AND ASSOCIATION; METHODS USED TO DETECT GENE DELETIONS AND POINT MUTATIONS; OVERVIEW OF INHERITED ENDOCRINE DISORDERS; APPROACH TO THE PATIENT , CURRENT DEVELOPMENTSREFERENCES; Part-02 - Neuroendocrinology and Pituitary Disease ; CHAPTER 5 - DEVELOPMENT OF THE PITUITARY*; PITUITARY DEVELOPMENT; TRANSCRIPTION FACTORS AND PITUITARY DEVELOPMENT; OTHER TRANSCRIPTION FACTORS; SIGNALING PATHWAYS IN PITUITARY DEVELOPMENT; NOTCHS; INTERACTIONS BETWEEN DIFFERENT MORPHOGENIC FACTORS; INDEPENDENT HH AND FGF SIGNALING IN PITUITARY ORGANOGENESIS; PITUITARY AND EPIGENETICS; STEM CELLS; SUMMARY; REFERENCES; chapter 6 - Prolactin; THE EVOLUTIONARY BIOLOGY OF PROLACTIN; THE BIOCHEMISTRY OF PROLACTIN , THE ONTOGENY AND PHYSIOLOGY OF PROLACTIN SECRETIONPATHOPHYSIOLOGY OF PROLACTIN SECRETION; PROLACTIN RECEPTORS AND SIGNAL TRANSDUCTION; THE PHYSIOLOGY AND PATHOPHYSIOLOGY OF PROLACTIN ACTIONS IN MAMMALS; SUMMARY; REFERENCES; CHAPTER 7 - DISORDERS OF PROLACTIN SECRETION AND PROLACTINOMAS; EPIDEMIOLOGY; PATHOGENESIS; PATHOLOGY; DIFFERENTIAL DIAGNOSIS OF HYPERPROLACTINEMIA; DIAGNOSIS OF PROLACTINOMAS; TREATMENT; REFERENCES; chapter 8 - Adrenocorticotropic Hormone; HISTORY; PROOPIOMELANOCORTIN GENE; ADRENOCORTICOTROPIC HORMONE AND RELATED PEPTIDES; REFERENCES , chapter 9 - Endocrine Rhythms, the Sleep-Wake Cycle, and Biological Clocks , English
    Language: English
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    FU Berlin
  • 8
    Online Resource
    Online Resource
    Harrisons Innere Medizin / (2020)
    [New York] :Mc Graw Hill Education, | Berlin :ABW Wissenschaftsverlag. | Stuttgart :Thieme.
    Details
    UID:
    edoccha_BV046860735
    Format: 1 Online-Ressource.
    Edition: 20. Auflage
    ISBN: 978-3-13-243524-7 , 3-13-243524-4
    Uniform Title: Harrison's principles of internal medicine
    Note: In Zusammenarbeit mit der Charité , Erschienen: Band 1-4 und Register
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 3-13-243524-4
    Language: German
    Subjects: Medicine
    RVK:
    YB 1501
    RVK:
    YB 1300
    RVK:
    YB 1500
    Keywords: Innere Medizin ; Lehrbuch
    DOI: 10.1055/b000000107
    Author information: Möckel, Martin
    Author information: Dietel, Manfred 1949-
    Author information: Suttorp, Norbert 1953-
    Author information: Siegmund, Britta 1971-
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    Open Access Request
    Charité
  • 9
    Online Resource
    Online Resource
    Endocrinology : Adult and Pediatric (2010)
    St. Louis :Elsevier Health Sciences,
    Details
    UID:
    edoccha_9960073388002883
    Format: 1 online resource (3076 p.)
    Edition: 6th ed.
    ISBN: 0-323-24062-3 , 0-323-22155-6 , 0-323-22153-X , 1-4557-1126-8
    Note: Description based upon print version of record. , ""Volume 1""; ""Front cover""; ""Half title page ""; ""Title page""; ""Copyright page""; ""Contributors""; ""Preface""; ""Table of contents""; ""Color plate""; ""PART 1: Principles of Endocrinology and Hormone Signaling""; ""Chapter 1: ENDOCRINOLOGY: Impact on Science and Medicine""; ""Definition and Scope of Endocrinology""; ""Historical Perspectives""; ""Principles of Hormone Action""; ""Hormone Action Through Receptors""; ""Role of the Clinical Endocrinologist""; ""Major Unsolved Problems""; ""REFERENCES""; ""Chapter 2: CONTROL OF HORMONE GENE EXPRESSION"" , ""The Central Dogma of Molecular Biology Revisited""""Chromatin: Accessibility of DNA to Control Factors""; ""Functional Anatomy of a Gene""; ""Functional Anatomy of the Promoter-Regulatory Region""; ""Transcription: Creating the Template for Protein Synthesis""; ""Posttranscriptional Modification of mRNA""; ""Translation: Regulated Protein Biosynthesis""; ""Posttranslational Modifications""; ""Regulated Secretion of Proteins""; ""RNAi Regulation of Gene Expression""; ""Hormonal Control of Gene Expression""; ""Functional Genomics and Proteomics""; ""REFERENCES""; ""BIBLIOGRAPHY"" , ""Chapter 3: CONTROL OF HORMONE SECRETION""""Morphology of Peptide Hormone�Secreting Endocrine Cells and the Regulated Secretory Pathway""; ""Synthesis, Processing, and Sorting of Preprohormone Precursors""; ""Composition of Mature Secretory Granules""; ""Sequential Stages of the Regulated Secretory Pathway""; ""Essential Protein Machinery for Dense-Core Granule Exocytosis""; ""Regulation of Exocytosis by Calcium""; ""Modulation of Calcium-Dependent Hormone Secretion by Protein Kinase C""; ""REFERENCES""; ""Chapter 4: INSULIN AND GROWTH FACTOR SIGNALING PATHWAYS"" , ""Receptor Tyrosine Kinases""""History""; ""Receptor Tyrosine Kinase Subfamilies""; ""Ligand Binding""; ""Mechanism of RTK Signaling""; ""Insulin/Mitogen Activation of Ser/Thr Phosphorylation-I: Signaling Downstream of PI-3-Kinase""; ""Mammalian Target of Rapamycin: A Central Regulator of Protein Synthesis in Insulin/Mitogen and Nutrient-Sensing Pathways""; ""Insulin/Mitogen Activation of Ser/Thr Phosphorylation-II: Signaling Through Ras and the MAP Kinases""; ""Additional Mammalian MAPKs and MAPK Pathways""; ""REFERENCES""; ""Chapter 5: HORMONE SIGNALING VIA G PROTEIN�COUPLED RECEPTORS"" , ""Classification of G Protein�Coupled Receptors""""Structural Features of G Protein�Coupled Receptors""; ""Posttranslational Modifications""; ""Diversity of Receptor-Ligand Binding""; ""Mechanism of Receptor Activation""; ""Receptor/G Protein Coupling and Selectivity""; ""G Protein�Dependent Effectors""; ""G Protein�Coupled Receptor Signaling Networks""; ""G Protein�Coupled Receptor Interacting Proteins""; ""G Protein�Coupled Receptor Dimerization""; ""Mechanisms of G Protein�Coupled Receptor Desensitization""; ""G Protein�Coupled Receptor Signaling and Disease"" , ""Acknowledgments"" , English
    Additional Edition: ISBN 1-336-24443-7
    Additional Edition: ISBN 1-4160-5583-5
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Charité
  • 10
    Online Resource
    Online Resource
    Endocrinology : Adult and Pediatric (2010)
    St. Louis :Elsevier Health Sciences,
    Details
    UID:
    edocfu_9960073388002883
    Format: 1 online resource (3076 p.)
    Edition: 6th ed.
    ISBN: 0-323-24062-3 , 0-323-22155-6 , 0-323-22153-X , 1-4557-1126-8
    Note: Description based upon print version of record. , ""Volume 1""; ""Front cover""; ""Half title page ""; ""Title page""; ""Copyright page""; ""Contributors""; ""Preface""; ""Table of contents""; ""Color plate""; ""PART 1: Principles of Endocrinology and Hormone Signaling""; ""Chapter 1: ENDOCRINOLOGY: Impact on Science and Medicine""; ""Definition and Scope of Endocrinology""; ""Historical Perspectives""; ""Principles of Hormone Action""; ""Hormone Action Through Receptors""; ""Role of the Clinical Endocrinologist""; ""Major Unsolved Problems""; ""REFERENCES""; ""Chapter 2: CONTROL OF HORMONE GENE EXPRESSION"" , ""The Central Dogma of Molecular Biology Revisited""""Chromatin: Accessibility of DNA to Control Factors""; ""Functional Anatomy of a Gene""; ""Functional Anatomy of the Promoter-Regulatory Region""; ""Transcription: Creating the Template for Protein Synthesis""; ""Posttranscriptional Modification of mRNA""; ""Translation: Regulated Protein Biosynthesis""; ""Posttranslational Modifications""; ""Regulated Secretion of Proteins""; ""RNAi Regulation of Gene Expression""; ""Hormonal Control of Gene Expression""; ""Functional Genomics and Proteomics""; ""REFERENCES""; ""BIBLIOGRAPHY"" , ""Chapter 3: CONTROL OF HORMONE SECRETION""""Morphology of Peptide Hormone�Secreting Endocrine Cells and the Regulated Secretory Pathway""; ""Synthesis, Processing, and Sorting of Preprohormone Precursors""; ""Composition of Mature Secretory Granules""; ""Sequential Stages of the Regulated Secretory Pathway""; ""Essential Protein Machinery for Dense-Core Granule Exocytosis""; ""Regulation of Exocytosis by Calcium""; ""Modulation of Calcium-Dependent Hormone Secretion by Protein Kinase C""; ""REFERENCES""; ""Chapter 4: INSULIN AND GROWTH FACTOR SIGNALING PATHWAYS"" , ""Receptor Tyrosine Kinases""""History""; ""Receptor Tyrosine Kinase Subfamilies""; ""Ligand Binding""; ""Mechanism of RTK Signaling""; ""Insulin/Mitogen Activation of Ser/Thr Phosphorylation-I: Signaling Downstream of PI-3-Kinase""; ""Mammalian Target of Rapamycin: A Central Regulator of Protein Synthesis in Insulin/Mitogen and Nutrient-Sensing Pathways""; ""Insulin/Mitogen Activation of Ser/Thr Phosphorylation-II: Signaling Through Ras and the MAP Kinases""; ""Additional Mammalian MAPKs and MAPK Pathways""; ""REFERENCES""; ""Chapter 5: HORMONE SIGNALING VIA G PROTEIN�COUPLED RECEPTORS"" , ""Classification of G Protein�Coupled Receptors""""Structural Features of G Protein�Coupled Receptors""; ""Posttranslational Modifications""; ""Diversity of Receptor-Ligand Binding""; ""Mechanism of Receptor Activation""; ""Receptor/G Protein Coupling and Selectivity""; ""G Protein�Dependent Effectors""; ""G Protein�Coupled Receptor Signaling Networks""; ""G Protein�Coupled Receptor Interacting Proteins""; ""G Protein�Coupled Receptor Dimerization""; ""Mechanisms of G Protein�Coupled Receptor Desensitization""; ""G Protein�Coupled Receptor Signaling and Disease"" , ""Acknowledgments"" , English
    Additional Edition: ISBN 1-336-24443-7
    Additional Edition: ISBN 1-4160-5583-5
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    FU Berlin
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