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  • 1
    UID:
    almahu_9949226769502882
    Format: XI, 178 p. 114 illus., 90 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811635755
    Series Statement: Research on Intelligent Manufacturing,
    Content: This book reports the new results of intelligent robot with hand-eye-brain, from the interdisciplinary perspective of information science and neuroscience. It collects novel research ideas on attractive region in environment (ARIE), intrinsic variable preserving manifold learning (IVPML) and biologically inspired visual congnition, which are theoretically important but challenging to develop the intelligent robot. Furthermore, the book offers new thoughts on the possible future development of human-inspired robotics, with vivid illustrations. The book is useful for researchers, R&D engineers and graduate students working on intelligent robots.
    Note: Introduction -- The Concept of "Attractive Region in Environment (ARIE)" and its Application in High-precision Tasks with Low-precision Systems -- The Compliance of Robotic Hands and Human-inspired Motion Model of Upper-limb with Fast Response and Learning Ability -- Learning an Intrinsic-Variable Preserving Manifold for Dynamic Visual Tracking -- Explicit Nonlinear Mapping for Manifold Learning with Neighborhood preserving polynomial embedding -- Biologically Inspired Visual Model with Memory and Association Mechanism -- Biologically Inspired Visual Model with Preliminary Cognition and Active Attention Adjustment -- Biologically Inspired Visual Cognition Model with Unsupervised Episodic and Semantic Feature Learning -- Conclusions and Future Research Directions.
    In: Springer Nature eBook
    Additional Edition: Printed edition: ISBN 9789811635748
    Additional Edition: Printed edition: ISBN 9789811635762
    Additional Edition: Printed edition: ISBN 9789811635779
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    UID:
    almahu_9949865070802882
    Format: VIII, 255 p. 17 illus., 15 illus. in color. , online resource.
    Edition: 2nd ed. 2024.
    ISBN: 9789819989218
    Content: This book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these conditions occur. Based on these findings, a series of novel treatment strategies are currently under development, and hopefully in a few years, medical practitioners will become more confident and optimistic when facing patients with these annoying and sometimes severe disorders. The contributing authors are world-renowned research scientists, who have made significant discoveries. The book is of interest to neuroscientists, neurologists and pharmacologists in both clinical and basic medical research field. In this second edition of the book, five existing chapters have been updated. Fivenew chapters have been added to reflect the lasted developments in the related field of research.
    Note: Chapter 1 Assessment of Itch and Pain in Animal Models and Human Subjects -- Chapter 2 Allergic Contact Dermatitis: A Model of Inflammatory Itch and Pain in Human and Mouse -- Chapter 3 Modulation of C-nociceptive Activities by Inputs from Myelinated Fibers -- Chapter 4 Pathophysiologic basis of the treatment of spontaneous pain -- Chapter 5 Neuropathic Pain: Sensory Nerve Injury or Motor Nerve Injury? -- Chapter 6 T cell and subsets in neuropathic pain -- Chapter 7 Astrocyte and microglia in chronic postsurgical pain -- Chapter 8 Dorsal spinal modulation of neuraxial opioids induced pruritus -- Chapter 9 Peripheral Nociceptors as Immune Sensors in the Development of Pain and Itch -- Chapter 10 Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy -- Chapter 11 Pain Modulation and the Transition from Acute to Chronic Pain -- Chapter 12 Integrated, Team-Based Chronic Pain Management: Bridges from Theory and Research to High Quality Patient Care -- Chapter 13 Research progress of long-acting analgesics for the treatment of chronic pain -- Chapter 14 Update in the Treatment of Neuropathic Pain -- Chapter 15 Mechanisms of peripheral sensitization in neuropathic pain.
    In: Springer Nature eBook
    Additional Edition: Printed edition: ISBN 9789819989201
    Additional Edition: Printed edition: ISBN 9789819989225
    Additional Edition: Printed edition: ISBN 9789819989232
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Cover
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  • 3
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press :
    UID:
    almahu_9949251557002882
    Format: 1 online resource (XII, 204 p. 25 illus.)
    Edition: 1st ed. 2011.
    ISBN: 1-60761-880-X
    Series Statement: Neuromethods, 49
    Content: With the loss of work days, the price of health care and payments for compensation, litigation, and malpractice, and the overwhelming cost of human suffering, chronic pain syndromes affect humanity enormously on both an economic and personal level. In Animal Models of Pain, expert investigators in the field provide a consolidated review of the current state of pain research by capturing the diversity of animal models that are used to investigate pain mechanisms, which range from surgical incision to mechanical compression and from spinal cord injury to cutaneous/local inflammation and beyond. As a volume in the respected Neuromethods series, this book delivers its vital content through detailed descriptions of a wide variety of step-by-step laboratory methods. Authoritative and cutting-edge, Animal Models of Pain seeks to lead scientists closer to the ultimate goal of improving the quality of life and relieving the unbearable burden of chronic pain for millions of people throughout the world.
    Note: Bibliographic Level Mode of Issuance: Monograph , Assessment of Pain in Animals -- Animal Models of Inflammatory Pain -- Animal Models of Visceral Pain -- Animal Models of Pain After Peripheral Nerve Injury -- Animal Models of Pain After Injury to the Spinal Ganglia and Dorsal Roots -- Localized Inflammatory Irritation of the Lumbar Ganglia: An Animal Model of Chemogenic Low Back Pain and Radiculopathy -- Animal Models of Central Neuropathic Pain -- Animal Models of Cancer Pain -- Animal Models of Diabetic Neuropathic Pain -- Animal Models of HIV-Associated Painful Sensory Neuropathy -- Animal Models of Postoperative Pain. , English
    Additional Edition: ISBN 1-60761-879-6
    Language: English
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  • 4
    UID:
    almahu_9947381963202882
    Format: 1 online resource (97 pages) : , illustrations; digital, PDF file(s).
    ISBN: 9782889193806
    Series Statement: Frontiers Research Topics
    Content: In the past decade, significant progresses have taken place in the field of cancer immunotherapeutics. Tumor-targeting or adjuvant immunotherapies are being developed for most human cancers including melanoma, prostate cancer, glioblastoma, sarcoma, lung carcinoma and hepatocellular carcinoma. New immunotherapeutics, such as Ipilimumab (anti-CTLA-4), have finished human trials and are approved by the US Food and Drug Administration (FDA) for clinical treatment; cell-based immunotherapies such as adoptive cell transfer (ACT) have either been approved (i.e., sipuleucel-T) for the treatment of selected neoplastic malignancies or reached the stage of phase II/III clinical trials. Immunotherapetics has become a sophisticated field. Multimodal therapeutic regimens comprising several functional modules (up to 5 in the case of ACT) have been developed to provide more focused therapeutic responses with improved efficacy and reduced side effects. Despite the tremendous developments, a major challenge mains: the lack of effective and clinically-applicable methods. Due to the complex immunological responses of patients that involve both the organs with neoplastic lesion and the whole immune system, it is difficult to provide comprehensive assessment of therapeutic efficacy and mechanism in patients. Despite the rapid adaptation of advanced medical imaging modalities such as MRI and PET/CT scan and the gold standard pathological examination, there is still unmet demand in the clinic to best evaluate cancer-specific cellular immunity and functions. Flow cytometry analysis has modernized hematology and immunology, and is currently being adapted to clinical immune monitoring through a multi-center endeavour in the US. The study aims to normalize, standardize, and implement flow cytometry-based cellular immunity assay in routine clinical tests. In parallel, new technologies including single cell polyfunctional analysis and immunophenotyping microchip are being developed for rapid, informative, and longitudinal monitoring of immune response to anti-cancer treatment in the clinical settings, shedding new light to future clinical trials of cancer immunotherapies. These technologies were designed to address the major challenges caused by the complexity and functional heterogeneity of cancer biology and cellular immunity, and allow for comprehensive survey of both tumor and the immune system to identify their mechanistic interplay in response to cancer immunotherapy. In addition, new computational tools are required to integrate high dimensional data sets from comprehensive, single-cell level measurements of patient’s immune responses and render most accurate and definitive diagnostic decision facilitated by new immune monitoring tools. This new generation of informative, personalized clinical diagnostic tools will likely contribute to new understanding of therapy mechanism, pre-treatment stratification of patients, ongoing therapeutic monitoring and assessment.
    Note: Bibliographic Level Mode of Issuance: Monograph , English
    Language: English
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  • 5
    Online Resource
    Online Resource
    Dordrecht : Springer Netherlands
    UID:
    b3kat_BV043547157
    Format: 1 Online-Ressource (XI, 147 p. 11 illus., 9 illus. in color)
    ISBN: 9789401775373
    Series Statement: Advances in Experimental Medicine and Biology 904
    Additional Edition: Erscheint auch als Druckausgabe ISBN 978-94-017-7535-9
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 6
    UID:
    almafu_9959899574502883
    Format: 1 online resource (XII, 569 p.)
    ISBN: 9783110584370
    Content: The work focuses on recent developments of the rapidly evolving field of Non-conventional Liquid Crystals. After a concise introduction it discusses the most promising research such as biosensing, elastomers, polymer films , photoresponsive properties and energy harvesting. Besides future applications it discusses as well potential frontiers in LC science and technology.
    Note: Frontmatter -- , Preface -- , Contents -- , List of contributing authors -- , 1 Introduction: from conventional to unconventional liquid crystals -- , 2 Unconventional liquid crystals: chemical aspects -- , 3 Ferroelectric liquid crystals and their application in modern displays and photonic devices -- , 4 Liquid crystalline materials for efficient solar energy harvesting -- , 5 Liquid crystal-based biosensing: exploiting the electrical and optical properties of various liquid crystals in quantitative bioassays -- , 6 Thermotropic liquids and liquid crystals from DNA and proteins -- , 7 Liquid crystals doped with ionic surfactants for electrically induced anchoring transitions -- , 8 Time-resolved dynamics of dye-doped liquid crystals and the origin of their optical nonlinearity -- , 9 Light reconfigurable chiral liquid crystal superstructure for dynamic diffraction manipulations -- , 10 Photoalignment of liquid crystalline polymers attained from the free surface -- , 11 Photoresponsive liquid-crystalline block copolymers with hierarchical structures -- , 12 Molecular modeling of liquid crystal elastomers -- , 13 Liquid crystal polymer films with high reflectivity -- , 14 Ultrathin films of nanomaterials: a lyotropic liquid crystalline system and its sensing application -- , 15 Quantum-dot-dispersed liquid crystals: mesogenic science to smart applications -- , Index , In English.
    Additional Edition: ISBN 9783110583519
    Additional Edition: ISBN 9783110583038
    Language: English
    Subjects: Physics
    RVK:
    Keywords: Aufsatzsammlung
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 7
    UID:
    almafu_BV042811762
    Format: 169 S. , graph. Darst. , 22 cm
    Original writing title: = 中國勞工運動史
    Original writing person/organisation: 馬超俊
    Uniform Title: Zhong guo lao gong yun dong shi
    Language: English
    Subjects: History
    RVK:
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  • 8
    UID:
    edochu_18452_26733
    Format: 1 Online-Ressource (12 Seiten)
    Content: Sauce-flavor Baijiu is one of the most complex and typical types of traditional Chinese liquor, whose trace components have an important impact on its taste and quality. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) is one of the most favorable analytical tools to reveal trace molecular components in complex samples. This study analyzed the chemical diversity of several representative sauce-flavor Baijiu using the combination of electrospray ionization (ESI) and FT-ICR MS. The results showed that ESI+ and ESI− exhibited different chemical features characteristic of trace components. Overall, sauce-flavor Baijiu was dominated by CHO class compounds, and the main specific compound types were aliphatic, highly unsaturated with low oxygen, and peptide-like compounds. The mass spectral parameters resolved by FT-ICR MS of several well-known brands were relatively similar, whereas the greatest variability was observed from an internally supplied brand. This study provides a new perspective on the mass spectrometry characteristics of trace components of sauce-flavor Baijiu and offers a theoretical foundation for further optimization of the gradients in Baijiu.
    Content: Peer Reviewed
    In: Basel : MDPI, 28,3
    Language: English
    URL: Volltext  (kostenfrei)
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  • 9
    UID:
    edochu_18452_23107
    Format: 1 Online-Ressource (17 Seiten)
    Content: Lignin is the second most abundant natural biopolymer, which is a potential alternative to conventional fossil fuels. It is also a promising material for the recovery of valuable chemicals such as aromatic compounds as well as an important biomarker for terrestrial organic matter. Lignin is currently produced in large quantities as a by-product of chemical pulping and cellulosic ethanol processes. Consequently, analytical methods are required to assess the content of valuable chemicals contained in these complex lignin wastes. This review is devoted to the application of mass spectrometry, including data analysis strategies, for the elemental and structural elucidation of lignin products. We describe and critically evaluate how these methods have contributed to progress and trends in the utilization of lignin in chemical synthesis, materials, energy, and geochemistry.
    Content: Peer Reviewed
    In: Basel : MDPI, 26,1
    Language: English
    URL: Volltext  (kostenfrei)
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  • 10
    UID:
    gbv_1758208686
    Format: 2, 219 Seiten , 图片
    Edition: 第1版
    Original writing title: 出土文献释读与先秦史研究
    Original writing person/organisation: 马超
    Original writing publisher: 北京 : 科学出版社
    ISBN: 9787030625267
    Language: Chinese
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