UID:
almafu_9959076715102883
Format:
1 online resource (187 p.)
ISBN:
3-318-02239-X
Series Statement:
Frontiers of hormone research,
Content:
Polycystic ovary syndrome (PCOS) is the most frequent disorder affecting women of reproductive age. Recent years have shown substantial advances in our understanding of the complex genetic, biochemical, metabolic, cardiovascular, and reproductive issues associated with PCOS. This book presents a comprehensive overview of recent clinical developments in identifying the phenotypic expression of women with PCOS resulting in a completely new recognition of its phenotypic variability. Metabolic and cardiovascular consequences of the syndrome are discussed in detail. Advances made in dealing with secondary forms of PCOS-like syndromes are presented as well as specific therapies of clinical manifestations and their outcomes. Additionally, a number of hot topics are included presenting genetic developments, endothelial causes leading to unfavorable outcomes, and novelties in therapeutic approaches dealing with metabolic and reproductive consequences. Covering phenotypic characteristics, diagnostic criteria, central pathophysiological mechanisms, metabolic, cardiovascular and reproductive aspects, and modern therapeutic approaches, this book is a useful tool for general practitioners, gynecologists, pediatricians, internists, endocrinologists, as well as cardiologists.
Note:
Description based upon print version of record.
,
""Cover""; ""Front Matter""; ""Contents""; ""Foreword""; ""Preface""; ""Polycystic Ovary Syndrome: Definitions, Phenotypes and Diagnostic Approach""; ""Abstract""; ""Definitions and Phenotypes""; ""Prevalence of Phenotypes Based on Different Criteria""; ""PCOS Phenotypes through Life Cycle""; ""Common Problems with Respect to Criteria Used for PCOS Classification""; ""Cardiovascular Risk, Metabolic and Hormonal Profile Comparison of Four Phenotypes of PCOS Based on the Rotterdam Criteria""; ""Differential Diagnosis of PCOS""; ""Diagnosing PCOS in Adolescence""
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""Towards a Tailor-Made Approach to Different PCOS Phenotypes""""Impact of Nutrition on PCOS Phenotypes and Metabolic/Hormonal Abnormalities � A Potential Role for Advanced Glycated End Products""; ""Conclusions""; ""References""; ""Pathophysiology of Polycystic Ovary Syndrome: The Role of Hyperandrogenism""; ""Abstract""; ""Hyperandrogenism""; ""The Disordered Folliculogenesis""; ""Is the Excess of AMH a Good Candidate for Explaining Anovulation?""; ""References""; ""Genetics of Polycystic Ovary Syndrome""; ""Abstract""; ""Limitations Associated with Genetics Studies in PCOS""
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""Candidate Gene Studies in PCOS""""Genome-Wide Association Studies in the Context of PCOS""; ""Conclusions""; ""Acknowledgements""; ""References""; ""Obesity, Adipokines and Metabolic Syndrome in Polycystic Ovary Syndrome""; ""Abstract""; ""Adipokines and Metabolic Syndrome in General Population""; ""Adipokines and Metabolic Syndrome in General Population: Trying to Get a Full View""; ""Adipokine Production in PCOS""; ""Androgens and Adipokine Production in PCOS""; ""Conclusions""; ""References""; ""Dyslipidemia and Oxidative Stress in PCOS""; ""Abstract""
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""Lipid Changes in Women with PCOS""""Oxidative Stress and PCOS""; ""Therapeutic Modalities for Dyslipidemia and Oxidative Stress in PCOS""; ""Conclusion""; ""Acknowledgement""; ""References""; ""Cardiovascular Risk and Subclinical Cardiovascular Disease in Polycystic Ovary Syndrome""; ""Abstract""; ""Epidemiology of Cardiovascular Disease in PCOS""; ""Cardiovascular Risk Factors in PCOS""; ""Subclinical Cardiovascular Disease in PCOS""; ""Medical Interventions and Cardiovascular Risk in PCOS""; ""Conclusion""; ""References""; ""Insulin Sensitizers in Polycystic Ovary Syndrome""; ""Abstract""
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""The Rationale for Using Insulin Sensitizers in PCOS""""Insulin-Sensitizing Agents""; ""Metformin: Mechanisms of Action""; ""Metformin: Clinical Effects""; ""Metformin: Side Effects""; ""Metformin Pharmacokinetics""; ""Metformin: Are the Effects Dose Dependent?""; ""Metformin: Factors Involved in Predicting Response""; ""Thiazolidinediones""; ""Thiazolidinediones: Mechanisms of Action""; ""Thiazolidinediones: Clinical Effects""; ""Metformin and Thiazolidinediones in PCOS: Comparative Studies""; ""PCOS and Severe Insulin Resistance: A Target for Thiazolidinediones?""; ""Conclusions""
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""References""
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English
Additional Edition:
ISBN 3-318-02238-1
Language:
English
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