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  • 1
    Online Resource
    Online Resource
    Norfolk, England :Caister Academic Press,
    UID:
    almahu_9948328251302882
    Format: 1 online resource (256 pages) : , illustrations
    ISBN: 9781910190722 (e-book)
    Additional Edition: Print version: Molecular biology of kinetoplastid parasites. Norfolk, England : Caister Academic Press, c2018 ISBN 9781910190715
    Language: English
    Keywords: Electronic books.
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    New York, NY :Springer New York :
    UID:
    almahu_9949419093502882
    Format: XX, 158 p. 45 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2008.
    ISBN: 9780387775708
    Series Statement: Advances in Experimental Medicine and Biology, 625
    Content: If viewed globally, the parasitic diseases pose an increasing threat to human health and welfare. The diseases caused by kinetoplastid protozoan parasites like Leishmania and Trypanosoma continue as a cause of suffering for many millions of people in both tropical and subtropical regions of the world. Leishmania species are found throughout Latin America, Africa and Asia. Trypanosoma cruzi that cause Chagas' disease is endemic in Latin America, while members of Trypanosoma brucei group are found in sub-Saharan Africa. Although the past two decades has witnessed commendable research efforts and technical advances in our understanding of the biochemistry, molecular and cell biology of these pathogens, the dreaded protozoal diseases caused by these organisms threaten mankind. Therapeutic tools for the treatment of most parasitic diseases are extremely limited. The development of parasites resistant to many of the available drugs is also responsible for the depressing picture of disease persistence and death. Development of commercially available vaccines is still far from reality, though research and trial programs continue.
    Note: Arsenite Resistance in Leishmania and Possible Drug Targets -- Unique Characteristics of the Kinetoplast DNA Replication Machinery Provide Potential Drug Targets in Trypanosomatids -- Drugs and Transporters in Kinetoplastid Protozoa -- Selective Lead Compounds against Kinetoplastid Tubulin -- Fishing for Anti-Leishmania Drugs: Principles and Problems -- Sterol 14-Demethylase Inhibitors for Trypanosoma cruzi Infections -- Histone Deacetylases -- Targeting Glycoproteins or Glycolipids and Their Metabolic Pathways for Antiparasite Therapy -- DNA Topoisomerases of Leishmania: The Potential Targets for Anti-Leishmanial Therapy -- Antiparasitic Chemotherapy: -- Searching the Tritryp Genomes for Drug Targets -- Purine and Pyrimidine Metabolism in Leishmania.
    In: Springer Nature eBook
    Additional Edition: Printed edition: ISBN 9781441926562
    Additional Edition: Printed edition: ISBN 9780387569116
    Additional Edition: Printed edition: ISBN 9780387775692
    Language: English
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  • 3
    Online Resource
    Online Resource
    New York, NY : Springer Science + Business Media | Austin, Tex. : Landes Bioscience
    UID:
    gbv_1647469503
    Format: Online-Ressource (digital)
    ISBN: 9780387775708
    Series Statement: Advances In Experimental Medicine And Biology 625
    Note: Includes bibliographical references and index
    Additional Edition: ISBN 9780387775692
    Additional Edition: Buchausg. u.d.T. Drug targets in kinetoplastid parasites New York, NY : Springer Science+Business Media LLC, 2008 ISBN 9780387775692
    Additional Edition: ISBN 0387775692
    Language: English
    Subjects: Chemistry/Pharmacy , Medicine
    RVK:
    RVK:
    Keywords: Leishmania ; Trypanosomen ; Kinetoplastida ; Kinetoplasten-DNS ; Pharmakotherapie ; Antiparasitäres Mittel ; Aufsatzsammlung
    URL: Cover
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