UID:
almafu_9958068626802883
Format:
1 online resource (177 p.)
ISBN:
1-281-72639-7
,
9786611726393
,
3-8055-8552-7
Series Statement:
Developments in ophthalmology, v. 42
Content:
Chromovitrectomy is a novel approach to visualize the vitreous or retinal surface during vitreoretinal surgery. In recent years, the widely used indocyanine green (ICG) has made the surgical maneuver of inner limiting membrane peeling tremendously safer and efficient. Also, numerous dyes have been applied in experimental settings with promising or devastating results. This volume highlights the major clinical and experimental results of currently used novel vital dyes. The first chapters describe the transparent structure of the vitreous body and summarize historical considerations to visualize its structure by optical coherence tomography, dye injections or autologous cells during surgery and for diagnostic purposes. The following contributions describe the advantages and disadvantages of ICG during vitreoretinal surgery and experimental applications. Alternative approaches by recently approved vital dyes such as trypan blue, patent blue and brilliant blue are evaluated in the subsequent chapters. Finally the last few chapters give an outlook on novel vital dyes, which are currently under evaluation, as well as alternative enzymatic approaches to remove the vitreous from the retinal surface. Being a timely update this publication will be indispensable reading for vitreoretinal surgeons and ophthalmic researchers.
Note:
Description based upon print version of record.
,
""Cover""; ""Contents""; ""List of Contributors""; ""Preface""; ""A Vitrectomy Is Done, When the Vitreous Is Gone!""; ""References""; ""To See the Invisible: The Quest of Imaging Vitreous""; ""Abstract""; ""Historical Perspective""; ""Vitreous Biochemistry""; ""Hyaluronan""; ""Collagen""; ""Supramolecular Organization""; ""Vitreous Embryology""; ""Interfaces""; ""Embryology of the Vitreous Body""; ""Vitreous Imaging""; ""In vitro Imaging""; ""In vivo Imaging""; ""Conventional Ophthalmoscopy and Biom croscopy""; ""Scanning Laser Ophthalmoscopy""; ""Ultrasonography""
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""Optical Coherence Tomography""""Combined OCT-SLO""; ""Spectroscopy""; ""Dynamic Light Scattering""; ""Conclusions""; ""References""; ""Historical Aspects and Evolution of the Application of Vital Dyes in Vitreoretinal Surgery and Chromovitrectomy""; ""Abstract""; ""Early Experiments with Endovenous Application of Dyes in Vitreoretinal Surgery""; ""Early Experiments with Intravitreal and Subretinal Injection of Dyes in Vitreoretinal Surgery""; ""Current Intraoperative Staining of Preretinal Membranes during the Vitreoretinal Surgery �Chromovitrectomy�""; ""Final Remarks""
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""Acknowledgment""""References""; ""Three Simple Approaches toVisualize the Transparent VitreousCortex during Vitreoretinal Surgery""; ""Abstract""; ""Intravitreous Application of Autologous Blood""; ""Crystalline Steroids Settle on the Surface of Vitreous Structures""; ""Preoperative Fluorescein Angiography May Stain the Vitreous Greenish""; ""Discussion""; ""Acknowledgment""; ""References""; ""Safety Parameters for Indocyanine Green in Vitreoretinal Surgery""; ""Abstract""; ""Indocyanine Green""; ""The Wrong Way to Go: Clinical Experience without Sufficient Preclinical Data""
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""Use and Misuse: How to Interpret Preclinical Data""""Clinical Experience and the Experimental Correlate""; ""Influence of Dye Persistence""; ""Influence of Illumination""; ""Influence of Osmolarity""; ""Summary and Conclusions""; ""References""; ""Toxicity of Indocyanine Green in Vitreoretinal Surgery""; ""Abstract""; ""Postmortem Findings""; ""In vitro Studies""; ""In vivo Studies""; ""Intravitreal Injection of Indocyanine Green in Rat Eyes""; ""Intravitreal Injection of Indocyanine Green in Rabbit Eyes""; ""Vitrectomy, Indocyanine Green Application, and Endoillumination""
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""Subretinal Injection of Indocyanine Green in Rabbit Eyes""""Vitrectomy and Internal Limiting Membrane Staining in Cat Eyes""; ""Ex vivo Models""; ""Indocyanine-Green-Assisted Internal Limiting Membrane Peeling""; ""Summary and Conclusion""; ""References""; ""Biomechanical Changes of the Internal Limiting Membrane after Indocyanine Green Staining""; ""Abstract""; ""Materials and Methods""; ""Preparation of Specimens""; ""Treatment Groups""; ""ICG Staining""; ""Light Sour e and Spectrophotometry""; ""Thickness Measurements""; ""Biomechanical Measurements""; ""Statisti al Evaluation""
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""Results""
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English
Additional Edition:
ISBN 3-8055-8551-9
Language:
English
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