Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (381 p.)

ISBN: 1-281-03824-5 , 9786611038243 , 0-08-053414-7

Series Statement: Hormones and Signaling

Content: Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development.Key Features* Includes information on:* Nuclear receptors, coactivators, and corepressors* Membrane receptors, kinases, and phosphorylation on cascades* Hormonal regulation of development* Calcium channels and neurotransmitters* Chromatin, transcription factors, and regulation of gene expression* JAK/STAT pathways* Hormone-regulated development and gene ""knock-out""

Note: Description based upon print version of record. , Front Cover; Hormones and Signaling; Copyright Page; Contents; Contributors; Preface; Chapter 1. Glucocorticoids and Oxysterols in Lymphoid Apoptosis; I. Introduction; II. Mechanisms of Action of the Glucocorticoid Receptor; III. Actions of Oxysterols on Lymphoid Cells; IV. Apoptosis; V. Glucocorticoids and Oxysterols Cause Apoptosis of CEM Cells; VI. Conclusions; References; Chapter 2. RAGE: A Receptor with a Taste for Multiple Ligands and Varied Pathophysiologic States; I. Introduction; II. Identification and Characterization of RAGE , III. Expression and Functions of RAGE: Endothelial Cells and Mononuclear PhagocytesIV. RAGE and Diabetes; V. RAGE and Amphoterin; VI. RAGE and Alzheimer's Disease; VII. Hypothesis; References; Chapter 3. The Function and Regulation of the G-Protein-Coupled Receptor Kinases; I. Introduction; II. The Regulation of Cellular Signaling; III. The G-Protein-Coupled Receptor Kinases; IV. The Regulation of the G-Protein-Coupled Receptor Kinases; V. Kinase Enzymology; VI. Receptor-Kinase Specificity; VII. Animal Models; VIII. Physiological Significance; IX. Conclusions; References , Chapter 4. Characteristics and Function of the Novel Estrogen Receptor ßI. Introduction; II. Cloning of ERß cDNA; III. Ligand-Binding Characteristics of ERß Protein; IV. Transactivation Function of ERß Protein; V. Expression of ERß mRNA; VI. Physiological Role of ER/3 Protein; VII. Concluding Remarks; References; Chapter 5. EGF Family Receptors and Their Ligands in Human Cancer; I. Introduction; II. EGF Family Receptors; III. EGF-like Growth Factors; IV. Activation of EGF Family Receptors; V. Clinical Significance of EGF Family Receptors , VI. Potential Clinical Application by Targeting of EGF Family Receptor Members and LigandsVII. Conclusion; References; Chapter 6. Fertilization: Common Molecular Signaling Pathways across the Species; I. Introduction; II. Oviductal Transport; III. Motility Modulation; IV. Gamete Adhesion; V. Acrosome Reaction; VI. Egg Plasma Membrane Interactions and Egg Activation; References; Chapter 7. The JNK Family of MAP Kinases: Regulation and Function; I. Introduction; II. Regulation of c-Jun Expression and Activity; III. Phosphorylation of the c-Jun Amino-Terminal Sites by JNK , IV. Signal Transduction Pathways Leading to Activation of JNK and Other MAP KinasesV. Other Substrates for the JNKs; VI. Biological Functions of JNK and Other MAP Kinase Pathways; VII. Conclusions and Future Considerations; References; Chapter 8. PPARa: Tempting Fate with Fat; I. PPARa as a Ligand-Activated Transcription Factor; II. Lipid Homeostasis: How Complex Can It Be?; III. PPARa Expression during Development and Adulthood; IV. PPARa and Its Activators: Open Relationships?; V. PPARa Ligands; VI. PPARa Functions; VII. Conclusion; References , Chapter 9. Molecular Mechanisms of Neuronal Survival and Apoptosis , English

Additional Edition: ISBN 0-12-312411-5

Language: English

UID:

Format: 1 online resource (xiii, 392 pages, 16 unnumbered pages of plates) : , illustrations (some color), maps

ISBN: 0-12-391467-1

Series Statement: Gale eBooks

Content: This is a comprehensive book addressing steroid disorders from hormonal, genetic, psychological, and surgical perspectives. It is meant to educate adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It will assist these specialists in the diagnosis and treatment of steroid disorders. The book is written for postgraduate and faculty-level physicians. The content consists of steroid disorders, genetic bases for the disorder and case presentations of each disorder. 〈ul

Note: Description based upon print version of record. , Front Cover; Genetic Steroid Disorders; Copyright; Dedication; Contents; Preface; Contributors; Chapter 1 - Introduction; References; Chapter 2 - Adrenal Development; INTRODUCTION; ADRENAL ORGANOGENESIS; MOLECULAR MECHANISMS THAT REGULATE ADRENAL DEVELOPMENT; ADRENAL DISEASES; References; Chapter 3A - Congenital Adrenal Hyperplasia Owing to 21-Hydroxylase Deficiency; INTRODUCTION; ENDOCRINE FUNCTION OF THE ADRENAL CORTEX; THE ADRENAL CORTEX AS TWO GLANDS; PATHOGENESIS OF 21-HYDROXYLASE DEFICIENCY; CLASSICAL CAH; NON-CLASSICAL CAH; DIAGNOSIS (HORMONAL AND GENETIC) , MOLECULAR MECHANISMS CREATING CYP21A2 GENETIC DEFECTSCLINICAL FEATURES; TREATMENT; PRENATAL DIAGNOSIS AND TREATMENT; References; Chapter 3B - The History of Prenatal Diagnosis of Congenital Adrenal Hyperplasia; INTRODUCTION; HORMONAL MEASUREMENTS IN AMNIOTIC FLUID; MOLECULAR GENETICS; DEXAMETHASONE TREATMENT AND CONTROVERSY; NON-INVASIVE PRENATAL DIAGNOSIS; FETAL SEX DETERMINATION; FUTURE DIRECTIONS; SUMMARY; References; Chapter 3C - Growth Hormone Therapy to Improve Adult Height in Patients with Congenital Adrenal Hyperplasia; INTRODUCTION; ADULT HEIGHT IN CAH , FACTORS AFFECTING ADULT HEIGHT IN CAHSTUDIES WITH GROWTH HORMONE TREATMENT TO IMPROVE ADULT HEIGHT IN CAH; CONCLUSION; References; Chapter 3D - Steroid 11β-Hydroxylase Deficiency and Related Disorders; INTRODUCTION; BIOCHEMISTRY OF ADRENAL STEROID BIOSYNTHESIS; GENETICS OF STEROID 11Β-HYDROXYLASE ISOZYMES; STEROID 11Β-HYDROXYLASE DEFICIENCY; ALDOSTERONE SYNTHASE (CORTICOSTERONE METHYLOXIDASE) DEFICIENCY; GLUCOCORTICOID-SUPPRESSIBLE HYPERALDOSTERONISM; Acknowledgments; References; Chapter 3E - Ambiguous Genitalia in Newborns; INTRODUCTION; TYPICAL SEX DETERMINATION AND DIFFERENTIATION , DISORDERS OF SEX DEVELOPMENT (DSD)OTHER CATEGORIES OF AMBIGUOUS GENITALIA; WORK-UP OF NEWBORNS WITH AMBIGUOUS GENITALIA; DIFFERENTIAL DIAGNOSIS; GENDER OF REARING; PARENTS AND CAREGIVERS OF CHILDREN WITH AMBIGUOUS GENITALIA; CONCLUSIONS; References; Chapter 3F - 3β-Hydroxysteroid Dehydrogenase Deficiency; THE 3Β-HSD FAMILY: AMINO ACID SEQUENCES AND ACTIVITIES; EPIDEMIOLOGY; CLINICAL FORMS; BIOLOGICAL DIAGNOSIS; MOLECULAR DIAGNOSIS; RELATIONSHIP BETWEEN GENOTYPE AND PHENOTYPE OF PATIENTS; PUBERTY AND FERTILITY; STRUCTURE-FUNCTION RELATIONSHIP; TREATMENT; References , Chapter 3G - Genetic Deficiencies of Cytochrome P450c17 (CYP17A1): Combined 17-Hydroxylase/17,20-Lyase Deficiency and Isolated 17,20-Lyase DeficiencySTRUCTURE OF THE GENE AND MAPPING IN THE HUMAN GENOME; GENETIC DEFECTS - MUTATION; HORMONAL ABNORMALITIES; DIAGNOSIS BASED ON STRUCTURE OF THE GENE AND MUTATIONS; EPIDEMIOLOGY; ETHNIC DIVERSITY AND CLUSTERS OF THE DEFECT; PSYCHOENDOCRINE ABNORMALITIES RESULTING FROM THE ENZYMATIC DEFECT; TREATMENT: MEDICAL AND SURGICAL; LONG-RANGE OUTCOME: MEDICAL AND PSYCHOLOGICAL (GENDER, COGNITION); LIFE CAREERS; PRISMATIC CASES , PRENATAL DIAGNOSIS AND TREATMENT , English

Additional Edition: ISBN 0-12-416006-9

Additional Edition: ISBN 1-299-81919-2

Language: English

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Format: 1 online resource (239 pages) : , illustrations (some color)

ISBN: 9781597567008 (e-book)

Additional Edition: Print version: Weinstein, Gregory S. TransOral robotic surgery (TORS). San Diego : Plural Pub., [2012] ISBN 9781597560740

Language: English

Keywords: Electronic books.

URL: Click to View

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Format: XV, 364 S , Ill., graph. Darst

ISBN: 0123124115

In: 1

Language: Undetermined

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Format: XIV, 404 S , Ill., graph. Darst

ISBN: 012181940X

Series Statement: Hormone action / ed. by Bert W. O'Malley ... Pt. E

Note: Literaturangaben

Additional Edition: Online-Ausg. Hormone action ; Pt. E: Nuclear structure and function New York, NY [u.a.] : Academic Press, 1975 ISBN 9780121819408

Language: English

URL: Inhaltsverzeichnis

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Format: XVI, 463 S. , graph. Darst.

ISBN: 012181937X

Series Statement: Hormone action / ed. by Bert W. O'Malley ... Pt. B

Note: Literaturangaben

Additional Edition: Online-Ausg. Hormone action ; Pt. B: Peptide hormones New York, NY [u.a.] : Academic Press, 1975 ISBN 9780121819378

Language: English

URL: Inhaltsverzeichnis

UID:

Format: XVII, 365 S. : Ill., graph. Darst.

Series Statement: (UCLA symposia on molecular and cellular biology 26)

Note: Literaturangaben

Language: Undetermined

UID:

Language: Undetermined

UID:

Format: 458 S.

ISBN: 0306390361

Series Statement: Advances in experimental medicine and biology 36

Note: Literaturangaben

Language: English

Subjects: Chemistry/Pharmacy , Biology

Keywords: Fortpflanzung ; Hormonrezeptor ; Konferenzschrift ; Konferenzschrift

UID:

Format: 1 online resource (xiii, 392 pages, 16 unnumbered pages of plates) : , illustrations (some color), maps

ISBN: 0-12-391467-1

Series Statement: Gale eBooks

Content: This is a comprehensive book addressing steroid disorders from hormonal, genetic, psychological, and surgical perspectives. It is meant to educate adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It will assist these specialists in the diagnosis and treatment of steroid disorders. The book is written for postgraduate and faculty-level physicians. The content consists of steroid disorders, genetic bases for the disorder and case presentations of each disorder. 〈ul

Note: Description based upon print version of record. , Front Cover; Genetic Steroid Disorders; Copyright; Dedication; Contents; Preface; Contributors; Chapter 1 - Introduction; References; Chapter 2 - Adrenal Development; INTRODUCTION; ADRENAL ORGANOGENESIS; MOLECULAR MECHANISMS THAT REGULATE ADRENAL DEVELOPMENT; ADRENAL DISEASES; References; Chapter 3A - Congenital Adrenal Hyperplasia Owing to 21-Hydroxylase Deficiency; INTRODUCTION; ENDOCRINE FUNCTION OF THE ADRENAL CORTEX; THE ADRENAL CORTEX AS TWO GLANDS; PATHOGENESIS OF 21-HYDROXYLASE DEFICIENCY; CLASSICAL CAH; NON-CLASSICAL CAH; DIAGNOSIS (HORMONAL AND GENETIC) , MOLECULAR MECHANISMS CREATING CYP21A2 GENETIC DEFECTSCLINICAL FEATURES; TREATMENT; PRENATAL DIAGNOSIS AND TREATMENT; References; Chapter 3B - The History of Prenatal Diagnosis of Congenital Adrenal Hyperplasia; INTRODUCTION; HORMONAL MEASUREMENTS IN AMNIOTIC FLUID; MOLECULAR GENETICS; DEXAMETHASONE TREATMENT AND CONTROVERSY; NON-INVASIVE PRENATAL DIAGNOSIS; FETAL SEX DETERMINATION; FUTURE DIRECTIONS; SUMMARY; References; Chapter 3C - Growth Hormone Therapy to Improve Adult Height in Patients with Congenital Adrenal Hyperplasia; INTRODUCTION; ADULT HEIGHT IN CAH , FACTORS AFFECTING ADULT HEIGHT IN CAHSTUDIES WITH GROWTH HORMONE TREATMENT TO IMPROVE ADULT HEIGHT IN CAH; CONCLUSION; References; Chapter 3D - Steroid 11β-Hydroxylase Deficiency and Related Disorders; INTRODUCTION; BIOCHEMISTRY OF ADRENAL STEROID BIOSYNTHESIS; GENETICS OF STEROID 11Β-HYDROXYLASE ISOZYMES; STEROID 11Β-HYDROXYLASE DEFICIENCY; ALDOSTERONE SYNTHASE (CORTICOSTERONE METHYLOXIDASE) DEFICIENCY; GLUCOCORTICOID-SUPPRESSIBLE HYPERALDOSTERONISM; Acknowledgments; References; Chapter 3E - Ambiguous Genitalia in Newborns; INTRODUCTION; TYPICAL SEX DETERMINATION AND DIFFERENTIATION , DISORDERS OF SEX DEVELOPMENT (DSD)OTHER CATEGORIES OF AMBIGUOUS GENITALIA; WORK-UP OF NEWBORNS WITH AMBIGUOUS GENITALIA; DIFFERENTIAL DIAGNOSIS; GENDER OF REARING; PARENTS AND CAREGIVERS OF CHILDREN WITH AMBIGUOUS GENITALIA; CONCLUSIONS; References; Chapter 3F - 3β-Hydroxysteroid Dehydrogenase Deficiency; THE 3Β-HSD FAMILY: AMINO ACID SEQUENCES AND ACTIVITIES; EPIDEMIOLOGY; CLINICAL FORMS; BIOLOGICAL DIAGNOSIS; MOLECULAR DIAGNOSIS; RELATIONSHIP BETWEEN GENOTYPE AND PHENOTYPE OF PATIENTS; PUBERTY AND FERTILITY; STRUCTURE-FUNCTION RELATIONSHIP; TREATMENT; References , Chapter 3G - Genetic Deficiencies of Cytochrome P450c17 (CYP17A1): Combined 17-Hydroxylase/17,20-Lyase Deficiency and Isolated 17,20-Lyase DeficiencySTRUCTURE OF THE GENE AND MAPPING IN THE HUMAN GENOME; GENETIC DEFECTS - MUTATION; HORMONAL ABNORMALITIES; DIAGNOSIS BASED ON STRUCTURE OF THE GENE AND MUTATIONS; EPIDEMIOLOGY; ETHNIC DIVERSITY AND CLUSTERS OF THE DEFECT; PSYCHOENDOCRINE ABNORMALITIES RESULTING FROM THE ENZYMATIC DEFECT; TREATMENT: MEDICAL AND SURGICAL; LONG-RANGE OUTCOME: MEDICAL AND PSYCHOLOGICAL (GENDER, COGNITION); LIFE CAREERS; PRISMATIC CASES , PRENATAL DIAGNOSIS AND TREATMENT , English

Additional Edition: ISBN 0-12-416006-9

Additional Edition: ISBN 1-299-81919-2

Language: English