Kooperativer Bibliotheksverbund

UID:

Format: 1 Online-Ressource (XV, 266 p. 1 illus).

Edition: 1st ed. 2023

ISBN: 978-981-9947-80-5

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-79-9

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-81-2

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-82-9

Language: English

DOI: 10.1007/978-981-99-4780-5

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XV, 266 p. 1 illus).

Edition: 1st ed. 2023

ISBN: 978-981-9947-80-5

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-79-9

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-81-2

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-82-9

Language: English

DOI: 10.1007/978-981-99-4780-5

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XV, 266 p. 1 illus)

Edition: 1st ed. 2023

ISBN: 9789819947805

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-79-9

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-81-2

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-82-9

Language: English

DOI: 10.1007/978-981-99-4780-5

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: XII, 377 p. 1 illus. , online resource.

Edition: 1st ed. 2022.

ISBN: 9789811689574

Content: This book reviews the role of the lung microbiome in the development and progression of lung diseases. It deals with the role of microbiota dysbiosis in influencing host defense and immunity leading to resistance, colonization, and disease exacerbation. The book delineates the complex interaction between pathogen and lung residual microbiota during disease conditions. It further highlights the potential role of lung microbiota as the key modulator of lung carcinogenesis and immune response against cancer cells. Lastly, it reviews technological developments for unraveling the lung microbiome that profoundly impacts clinical diagnostics. This book is an essential resource for the scientists working in pulmonary diseases, pharmaceutical & clinical sciences, and pulmonary clinicians.

Note: Introduction to Lung Diseases -- Introduction to Microbiome -- Role of Microbiome in Inflammation -- The interplay of microbiome, inflammation, and immunity in inflammatory lung diseases -- Microbiome in Asthma -- Microbiome in Chronic Obstructive Pulmonary Disease -- Microbiome in Asthma-COPD Overlap syndrome (ACO) -- Microbiome in ARDS (Acute Respiratory Distress Syndrome) -- Role of brain-gut- microbiome axis in Depression co-morbid with COPD or Asthma -- Microbiome in Lung Cancer -- Microbiome in Pulmonary Tuberculosis -- Lung Microbiome: Friend or Foe of Mycobacterium tuberculosis -- Microbiome in Idiopathic Pulmonary Fibrosis. Microbiome in SARS-Cov2 (Covid-19) -- Status of the microbiome in SARS-Cov2 (Covid-19) -- Microbiome in Influenza-A Virus Infection -- Microbiome in Upper Respiratory Tract Infection (URTI) -- Challenges in understanding the lung microbiota -- Microbiome in Inflammatory Lung Diseases: Challenges and Future Prospects -- Microbiota targeted via nanotechnology for lung cancer therapy: Challenges and future perspectives.

In: Springer Nature eBook

Additional Edition: Printed edition: ISBN 9789811689567

Additional Edition: Printed edition: ISBN 9789811689581

Additional Edition: Printed edition: ISBN 9789811689598

Language: English

DOI: 10.1007/978-981-16-8957-4

URL: https://doi.org/10.1007/978-981-16-8957-4

URL: lizenzpflichtig

URL: Cover

UID:

Format: XV, 266 p. 1 illus. , online resource.

Edition: 1st ed. 2023.

ISBN: 9789819947805

Content: This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.

Note: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Introduction to Epigenetics -- Chapter 3._Epigenetic mechanisms in Inflammation -- Chapter 4. Epigenetic regulator of inflammatory gene expression -- Chapter 5. Epigenetics of Asthma -- Chapter 6_. Epigenetic optimization in chronic obstructive pulmonary disease (COPD -- Chapter 7. Epigenetics of Lung Cancer -- Chapter 8. Epigenetics of Pulmonary Tuberculosis -- Chapter 9. Epigenetics of Idiopathic Pulmonary Fibrosis -- Chapter 10. Epigenetics of influenza-A virus infection -- Chapter 11. Epigenetics of rhinovirus -- Chapter 12. Epigenetics of SARS-Cov2 (Covid-19) -- Chapter 13. Epigenetics of Haemophilus Influenzae -- Chapter 14. Future Prospects and Challenges -- Chapter 15. Targeting epigenetics in pulmonary arterial hypertension.

In: Springer Nature eBook

Additional Edition: Printed edition: ISBN 9789819947799

Additional Edition: Printed edition: ISBN 9789819947812

Additional Edition: Printed edition: ISBN 9789819947829

Language: English

DOI: 10.1007/978-981-99-4780-5

URL: https://doi.org/10.1007/978-981-99-4780-5

URL: lizenzpflichtig

UID:

Format: 1 Online-Ressource (XII, 377 p. 1 illus)

Edition: 1st ed. 2022

ISBN: 9789811689574

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-56-7

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-58-1

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-59-8

Language: English

DOI: 10.1007/978-981-16-8957-4

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 online resource (506 p.)

ISBN: 1-280-63655-6 , 9786610636556 , 0-08-046466-1

Series Statement: Methods in enzymology ; v. 411

Content: Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techni

Note: Description based upon print version of record. , Cover Page; Table of Contents; Contributors to Volume 411; Volumes in Series; Chapter 1: RNA Extraction for Arrays; Introduction; Blood as a Biological Specimen; Overview of the LeukoLOCK Procedure for Isolation of RNA from Whole Blood Samples; Use of Solid Tissues for Gene Expression Analysis; RNA Quality Measurements for Microarray Analysis; Conclusion; Acknowledgments; References; Chapter 2: Analyzing Micro-RNA Expression Using Microarrays; Introduction; Micro-RNAs Are Important Factors in Human Cancer; Focus of This Chapter; Microarray Platforms , miRNA Preparation for Analysis on Microarrays Analysis of miRNA Microarray Results; Methods of Normalization for miRNA Microarray Experiments; Case Study: miRNA Microarray Expression Analysis of Human Lung and Placental Tissues; Scanning and Data Extraction; Sample Size Calculation; Calculation of Array-Specific Thresholds; Global Normalization; Statistical Differential Analysis; Hierarchical Clustering; Conclusion; Acknowledgments; References; Chapter 3: Troubleshooting Microarray Hybridizations; Introduction; General Considerations; Printing; Sample Preparation and Labeling , Background Fluorescence Hybridization Quality Assessment; Concluding Remarks; Acknowledgments; Internet Resources; References; Chapter 4: Use of External Controls in Microarray Experiments; Introduction; Description and Availability of External Controls; Assessment of Array Performance Using External RNA Controls; Methods for Synthesis and Utilization of External RNA Controls; Evaluation of Data Analysis Methodology Using Spike-In Data Sets; Concluding Remarks; Acknowledgments; References; Chapter 5: Standards in Gene Expression Microarray Experiments; Introduction; Variability , A Digression: Traceability, Validation, and Uncertainty Standards in Traceability, Validation, and Uncertainty for DNA Microarray Gene Expression Profiles; Data Exchange Standards; Standards in the Gene Expression Process Model; The Future; References; Chapter 6: Scanning Microarrays: Current Methods and Future Directions; Introduction; Overview of the Scanning Process; User-Controlled Parameters; Instrumentation/Hardware Effects; Alternative Scanning Technologies Provide Advantages; Specific Considerations for Multiple Slide, Multiple Scanner, and/or Multiple Laboratory Experiments , Conclusions Acknowledgments; References; Chapter 7: An Introduction to BioArray Software Environment; Introduction; Getting Started; The Basics of BASE; Working with BASE; References; Chapter 8: Bioconductor: An Open Source Framework for Bioinformatics and Computational Biology; Introduction: Bioconductor in Brief; Technical Details; Array Preprocessing; Addressing Multiple Comparisons; Conclusions: Data Analysis for High-Throughput Biology and Bioconductor; Acknowledgment; References; Chapter 9: TM4 Microarray Software Suite; Introduction; MADAM; Spotfinder; Spotfinder Protocol Description , MIDAS , English

Additional Edition: ISBN 0-12-182816-6

Language: English

UID:

Format: 1 Online-Ressource (XII, 377 p. 1 illus).

Edition: 1st ed. 2022

ISBN: 978-981-1689-57-4

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-56-7

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-58-1

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-59-8

Language: English

DOI: 10.1007/978-981-16-8957-4

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XV, 266 p. 1 illus).

Edition: 1st ed. 2023

ISBN: 978-981-9947-80-5

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-79-9

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-81-2

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-9947-82-9

Language: English

DOI: 10.1007/978-981-99-4780-5

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XII, 377 p. 1 illus).

Edition: 1st ed. 2022

ISBN: 978-981-1689-57-4

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-56-7

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-58-1

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1689-59-8

Language: English

DOI: 10.1007/978-981-16-8957-4

URL: Volltext  (URL des Erstveröffentlichers)