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  • 1
    Book
    Book
    San Diego [u.a.] : Academic Press
    UID:
    b3kat_BV013277507
    Format: XXII, 788 S. , Ill., graph. Darst.
    ISBN: 0125680481
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Biomolekül ; Reaktionskinetik ; Biomolekül ; Enzymkinetik ; Wörterbuch
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  • 2
    Online Resource
    Online Resource
    San Diego, Calif. :Elsevier Academic,
    UID:
    almafu_BV042300285
    Format: 1 Online-Ressource (XXI, 892 S.) : , Ill., graph. Darst.
    ISBN: 1-282-73796-1 , 978-1-282-73796-9
    Note: Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. - Historical analysis of kinetic principles including advanced enzyme science - Provides both theoretical and practical measurements tools - Coverage of single molecular kinetics - Examination of force generation mechanisms - Discussion of organic and inorganic enzyme reactions
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-0-12-380924-7
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 0-12-380924-X
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
    RVK:
    RVK:
    RVK:
    Keywords: Enzymkinetik ; Enzymkatalyse ; Electronic books ; Electronic books
    URL: Volltext  (Connect to full text)
    URL: Volltext  (Connect to full text)
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  • 3
    UID:
    almahu_9947366650602882
    Format: 1 online resource (915 p.)
    ISBN: 1-282-73796-1 , 9786612737961 , 0-12-380925-8
    Content: Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also
    Note: Includes index. , Front Cover; Enzyme Kinetics:Catalysis & Control; Copyright; Contents; Preface; Chapter 1An Introduction to Enzyme Science; CATALYSIS; BIOLOGICAL CATALYSIS; DEVELOPMENT OF ENZYME KINETICS; THE CONCEPT OF A REACTIONMECHANISM; EXPLAINING THE EFFICIENCY OF ENZYME CATALYSIS; PROSPECTS FOR ENZYME SCIENCE; FURTHER READING; Chapter 2Active Sites and their Chemical Properties; ENZYME ACTIVE SITES; FORCES AFFECTING ENZYME STRUCTURAL STABILITY AND INTERACTIONS; ACTIVE-SITE DIVERSIFICATION; ADDITIONAL FUNCTIONAL GROUPS IN ENZYME ACTIVE SITES; METAL IONS IN ENZYME ACTIVE SITES , ACTIVE SITES OF ENZYMES ACTING ON POLYMERIC SUBSTRATESBASIC ORGANIC CHEMISTRYOF ENZYME ACTION; DETECTING COVALENT INTERMEDIATES IN ENZYME REACTIONS; BASICS OF ENZYME STEREOCHEMISTRY; ELECTRON TRANSFER REACTIONS; FURTHER READING; APPENDIX: ACCESSING ENZYMESTRUCTURES; Chapter 3Fundamentals of Chemical Kinetics; TIMESCALE OF CHEMICAL PROCESSES; THE EMPIRICAL RATE EQUATION; REACTION RATE, ORDERAND MOLECULARITY; BASIC STRATEGIES FOR EVALUATING RATE PROCESSES; COMPOSITE MULTI-STAGE (MULTI-STEP) MECHANISMS; THERMAL ENERGY: THE BOLTZMANN DISTRIBUTION LAW; SOLUTION BEHAVIOR OF REACTING MOLECULES , TRANSITION-STATE THEORYCHEMICAL CATALYSIS; REACTION COORDINATE DIAGRAMS; THERMODYNAMIC PRINCIPLES; CONCLUDING REMARKS; FURTHER READING; Chapter 4Practical Aspects of Measuring Initial Rates and Reaction Parameters; DESIGN OF INITIAL-VELOCITY ENZYME ASSAYS; ENZYME PURIFICATION; COUPLED (OR AUXILIARY) ENZYME ASSAYS; BASIC UV/VISIBLE ABSORPTION SPECTROSCOPY; BASIC FLUORESCENCE SPECTROSCOPY; MEASURING REACTION RATESWITH ISOTOPES; MULTISUBSTRATE KINETICSAND INHIBITOR KINETICS; ANALYSIS OF ENZYME RATE DATA; WORKING WITH ATP-DEPENDENT ENZYMES; REGENERATING NUCLEOSIDE59-TRIPHOSPHATE SUBSTRATES , EQUILIBRIUM CONSTANT DETERMINATIONSCONCLUDING REMARKS; FURTHER READING; Chapter 5Initial-Rate Kinetics of One-Substrate Enzyme-Catalyzed Reactions; MICHAELIS-MENTEN TREATMENT; THE BRIGGS-HALDANE STEADY-STATE TREATMENT; CATALYSIS INVOLVING TWOOR MORE INTERMEDIATES; ADDITIONAL COMMENTS ON FUNDAMENTAL KINETIC PARAMETERS; REACTION PROGRESS CURVE ANALYSIS; RIBOZYME KINETICS; PROTEASOME KINETICS; ISOMERIZATION MECHANISMS; SIMULTANEOUS ACTION OF AN ENZYME ON DIFFERENT SUBSTRATES; ENANTIOMERIC ENRICHMENTAND ANOMERIC SPECIFICITY; SIMULTANEOUS ACTION OF TWO ENZYMES ON THE SAME SUBSTRATE , INDUCED-FIT MECHANISMSKINETICS OF ENZYMES ACTINGON POLYMERIC SUBSTRATES; CONCLUDING REMARKS; FURTHER READING; Chapter 6Initial-Rate Kinetics of Multi-Substrate Enzyme-Catalyzed Reactions; BISUBSTRATE KINETIC MECHANISMS; DERIVATION STEADY-STATE BISUBSTRATE RATE EQUATIONS; DERIVATION OF RAPID EQUILIBRIUM BISUBSTRATE RATE EQUATIONS; PING PONG BI BI MECHANISM; GRAPHICAL AND QUANTITATIVE ANALYSIS OF BISUBSTRATE KINETICS; THREE-SUBSTRATE ENZYME KINETICS; MULTISUBSTRATE ''ISO'' MECHANISMS; KINETIC PROPERTIES OF ENZYMESEXHIBITING BRANCHED TRANSFERPATHWAYS; CONCLUDING COMMENTS , APPENDIX: ENZYMES WITH DEFINEDMULTISUBSTRATE KINETIC MECHANISMS , English
    Additional Edition: ISBN 0-12-380924-X
    Language: English
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  • 4
    UID:
    b3kat_BV000085476
    Format: XXI, 830 S.
    ISBN: 0121819647
    Series Statement: Methods in enzymology 87
    In: C
    Language: English
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  • 5
    UID:
    almahu_BV014124698
    Format: IX, 929 S. : , graph. Darst.
    ISBN: 0-12-568041-4
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Enzym ; Nomenklatur ; Enzym ; Wörterbuch ; Wörterbuch
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  • 6
    Book
    Book
    New York, NY [u.a.] : Acad. Press
    UID:
    gbv_028314387
    Series Statement: Methods in enzymology ...
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Enzymkinetik ; Enzymkatalyse ; Enzymologie ; Enzymkatalyse ; Energetik ; Aufsatzsammlung
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  • 7
    Book
    Book
    New York, NY [u.a.] : Acad. Press
    UID:
    gbv_184844495
    Format: XXV, 662 S. , Ill., graph. Darst.
    ISBN: 0121821501
    Series Statement: Enzyme kinetics and mechanism / ed. by Daniel L. Purich Pt. D
    Additional Edition: Erscheint auch als Online-Ausgabe Enzyme kinetics and mechanism ; Pt. D: Developments in enzyme dynamics New York, NY [u.a.] : Acad. Press, 1995 ISBN 9780121821500
    Language: English
    Subjects: Biology
    RVK:
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  • 8
    UID:
    almahu_9947366360402882
    Format: 1 online resource (551 p.)
    ISBN: 1-281-05330-9 , 9786611053307 , 0-08-048938-9
    Series Statement: Methods in enzymology ; v. 354
    Content: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today?truly an essential publication for researchers in all fields of life sciences.Key Features* Spectroscopic Detection of Reaction Intermediates* Isotopic and Kenetic Dete
    Note: Description based upon print version of record. , Cover; Table of Contents; CONTRIBUTORS TO VOLUME 354; Preface; Volumes in Series; Chapter 1. Covalent Enzyme-Substrate Compounds: Detection and Catalytic Competence; Chapter 2. Rapid Mix-Quench MALDI-TOF Mass Spectrometry for Analysis of Enzymatic Systems; Chapter 3. Pre-Steady-State Kinetics of Enzymatic Reactions Studied by Electrospray Mass Spectrometry with On-Line Rapid-Mixing Techniques; Chapter 4. Trapping of α-Glycosidase Intermediates; Chapter 5. Trapping Covalent Intermediates on β-Glycosidases , Chapter 6. 2-Hydroxy-6-keto-nona-2,4-diene 1,9-Dioic Acid 5,6-Hydrolase: Evidence from 18O Isotope Exchange for gem-Diol IntermediateChapter 7. Nucleoside-Diphosphate Kinase: Structural and Kinetic Analysis of Reaction Pathway and Phosphohistidine Intermediate; Chapter 8. Galactose-1-Phosphate Uridylyltransferase: Kinetics of Formation and Reaction of Uridylyl- Enzyme Intermediate inWild-Type and Specifically Mutated Uridylyltransferases; Chapter 9. Kinetic Evidence for Covalent Phosphoryl- Enzyme Intermediate in Phosphotransferase Activity of Human Red Cell Pyrimidine Nucleotidases , Chapter 14. Transaldolase B: Trapping of Schiff Base Intermediate between Dihydroxyacetone and ε-Amino Group of Active-Site Lysine Residue by Borohydride ReductionChapter 15. T4 Endonuclease V: Use of NMR and Borohydride Trapping to Provide Evidence for Covalent Enzyme-Substrate Imine Intermediate; Chapter 16. Detection of Covalent Tetrahedral Adducts by Differential Isotope Shift 13C NMR: Acetyl- Enzyme Reaction Intermediate Formed by 3-Hydroxy-3-methylglutaryl-CoA Synthase , Chapter 17. Detection of Intermediates in Reactions Catalyzed by PLP-Dependent Enzymes: O-Acetylserine Sulfhydrylase and Serine-Glyoxalate AminotransferaseChapter 18. Protein Tyrosine Phosphatases: X-Ray Crystallographic Observation of Cysteinyl-Phosphate Reaction Intermediate; Chapter 19. GTP:GTP Guanylyltransferase: Trapping Procedures for Detecting and Characterizing Chemical Nature of Enzyme-Nucleotide Phosphoramidate Reaction Intermediate; Chapter 20. γ-Glutamyl Thioester Intermediate in Glutaminase Reaction Catalyzed by Escherichia coli Asparagine Synthetase B , Chapter 21. γ-Glutamyltranspeptidase and γ-Glutamyl Peptide Ligases: Fluorophosphonate and Phosphonodifluoromethyl Ketone Analogs as Probes of Tetrahedral Transition State and γ-Glutamyl- Phosphate Intermediate , English
    Additional Edition: ISBN 0-12-182257-5
    Language: English
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  • 9
    UID:
    almafu_9959327503202883
    Format: 1 online resource (xii, 283 pages, 4 unnumbered pages of plates) : , illustrations (some color)
    ISBN: 9780470123195 , 0470123192
    Series Statement: Advances in enzymology ; volume 73
    Note: Classics in enzymology: the kinetics of the enzyme-substrate compound of peroxidase / Britton Chance -- Rethinking fundamentals of enzyme action / Dexter B. Northrop -- Adenylosuccinate synthetase: recent developments / Richard B. Honzatko, Mark M. Stayton and Herbert J. Fromm -- Nucleoside momophosphate kinases: structure, mechanism and substrate specificity / Honggao Yan and Ming-Daw Tsai -- Enzymology of NAD synthesis / Giulio Magni [and others] -- Solution structure and mechanism of MutT pyrophosphohydrolase / A.S. Mildvan, D.J. Weber and C. Abeygunawardana -- The enyzmes of glutathione synthesis: [gamma]-glutamylcysteine synthetase / Owen W. Griffith and R. Timothy Mulcahy.
    Additional Edition: ISBN 0470123192
    Additional Edition: ISBN 0471246441
    Additional Edition: ISBN 9780470123195
    Additional Edition: ISBN 9780471246442
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books.
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  • 10
    UID:
    almafu_9959329063002883
    Format: 1 online resource : , illustrations
    ISBN: 9780470123201 , 0470123206
    Series Statement: Advances in enzymology ; volume 74
    Note: Past editor: Professor F.F. Nord (Founding Editor) volumes 1-34: Professor Alton Meister 35-71.
    Additional Edition: Print version: Advances in enzymology and related areas of molecular biology. volume 74. Hoboken, N.J. ; New York : John Wiley & Sons, 1941 ISBN 0471246441
    Additional Edition: ISBN 9780471246442
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books.
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